Reposted by Audrey Desgrange
New publication, new insights into left-right patterning in mice.
We revisit the role of the node, from a left-right organiser to one biasing factor among others.
www.science.org/doi/10.1126/...
science.org
Wnt and Nodal asymmetries stratify mouse laterality phenotypes in the absence of node flow
Asymmetry establishment without node flow reveals an alternative symmetry-breaking event in the mesoderm involving WNT signaling.