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Adriano Bolondi

@adrianobolondi.bsky.social
359 followers 474 following 38 posts

La Caixa Junior Leader Fellow @crg.eu, previous MeissnerLab @molgen.mpg.de. Interested in how cells and genes make embryos. Previous #EMBO & #MSCA fellow

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Reposted by Adriano Bolondi
Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 28/09/2026
The ovary actively 'counts' its eggs, preparing the same proportion for ovulation, at different stages of life 📹 Arturo D’Angelo et al @bokelab.bsky.social @crg.eu in @nataging.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers
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Meng Zhu @zhumeng123.bsky.social · 24/09/2026
Two years since the 1st submission, our work on limb heterochrony is finally out! 🎉🎊 @cellcellpress.bsky.social Delayed hindlimb dev vs forelimb is a widely conserved trait in mammals. We show that maternal O2 regulates this phenotype 👉🏻 shorturl.at/MGrwl
shorturl.at
Shifts in embryonic oxygen levels cue heterochrony in limb initiation
Mammalian embryos see a substantial increase in available oxygen once the placenta forms. This increase in oxygen exposure serves as a trigger for initiating the development of the hindlimb, thus cont...
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Reposted by Adriano Bolondi
Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 17/09/2026
Huge interest in our "Women Shaping STEM" event with group leader @julianeg.bsky.social – co-hosted with @cibss.bsky.social. Great insights into her personal journey and decision-making moving from Paris → Berlin → Freiburg, while climbing the career ladder from PhD to PI! 🪜 Thank you!
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Marta Shahbazi @marta-shahbazi.bsky.social · 11/09/2026
Really happy and honoured! Thank you so much!
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Joe Bowness @joebowness.bsky.social · 01/09/2026
Very happy to share the first pre-print from my postdoc work with @larsplus.bsky.social (which we also presented at the excellent @isehsociety.bsky.social Annual Meeting last weekend). Here we performed a CRISPRi Perturb-seq screen targeting >500 transcriptional regulators in ex vivo mouse HSPCs.
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Manuel Irimia @mirimiam.bsky.social · 03/09/2026
🚨🚨🚨 As part of the MSCA-DN DECODES, we're looking for a PhD student to study splicing programs in beta cells and diabetes at @melisupf.bsky.social @crg.eu Join 14 other PhD students across Europe to decipher the splicing code in human disease. More info below 👇 www.findaphd.com/phds/project...
findaphd.com
DECODES at University of Santiago de Compostela on FindAPhD.com
PhD Project - DECODES at University of Santiago de Compostela, listed on FindAPhD.com
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Reposted by Adriano Bolondi
MwahahahahahadScientist @mads100tist.bsky.social · 29/08/2026
Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)
biorxiv.org
FOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopy
Understanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar...
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Reposted by Adriano Bolondi
Kristina Stapornwongkul @kstapornwongkul.bsky.social · 06/08/2026
First published teamwork of the lab 🎉! We wrote a review about emerging concepts of how metabolism promotes, regulates and changes during gastrulation. We hope it will be useful for anyone interested in the emerging field of developmental metabolism. www.sciencedirect.com/science/arti...
sciencedirect.com
A metabolic view of gastrulation: Coordinating signalling, epigenetics and morphogenesis
Gastrulation is the morphogenetic process by which the single-layered pluripotent epiblast is reorganised into the three germ layers and the basic bod…
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Reposted by Adriano Bolondi
Christopher Thomas @ovarylab.bsky.social · 27/07/2026
Check out our new review in Reproduction! 💥🥚🔬 In “The explosion of life”, @anitabichisecchi.bsky.social, @petramikec.bsky.social and I explore how live imaging has shaped our understanding of ovulation, revealing the cellular and tissue dynamics that drive egg release. doi.org/10.1093/repr...
Seeing is believing: historical snapshots of ovulation. Representative stills from landmark live-imaging studies capturing periovulatory
dynamics and follicle rupture.
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Reposted by Adriano Bolondi
Miquel Anglada-Girotto @m1quelag.bsky.social · 28/07/2026
1/ We’ve been working on making it easier to fine-tune AlphaGenome on new RNA-seq samples, with a focus on one of my favourite regulatory layers: splicing! Blog post: genomicsxai.github.io/blogs/2026-0...
genomicsxai.github.io
Beyond coverage tracks: fine-tuning AlphaGenome's splicing heads from scratch
Summary DeepMind has released AlphaGenome’s code and model weights, and the community has since developed alphagenome_ft and alphagenome-pytorch to enable seamless fine-tuning in both JAX and PyTorch....
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Darío Lupiáñez @dariloops.bsky.social · 21/07/2026
🚨 Job Alert - Please share 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! ✅ 4 years fully funded PhD position 💻🧪 Experimental or computational backgrounds welcome 👇 Details below #PhDPosition #PhDOpportunity #AcademicJobs
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Jesse Veenvliet @jesseveenvliet.bsky.social · 08/07/2026
Just approved an order for standard lab consumables. Prices have nearly doubled since starting the lab. Meanwhile, the bar for publishing keeps rising, requiring ever more costly experiments, while grant budgets barely changed. Hard to see how this is a sustainable trajectory for academic research.
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Matthew L. Kraushar @matthewkraushar.bsky.social · 06/07/2026
We face great challenges, but our resolve is greater & vision clearer for the future of neuroscience. The @young-pi-neuro26.bsky.social network is stronger than ever. Thanks co-organizers, speakers @tjryan.bsky.social, @drosostalis.bsky.social, @anne-schreiter.bsky.social, & our core ➡️ participants!
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Matthew L. Kraushar @matthewkraushar.bsky.social · 06/07/2026
A special thanks to our hosts @adrianobolondi.bsky.social and the lovely @crg.eu Barcelona. This was an official @fens.org Satellite Event, and we thank our many sponsors: youngpisymposium2026.com
youngpisymposium2026.com
Young PI Symposium 2026
Visit the post for more.
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Reposted by Adriano Bolondi
Centre de Regulació Genòmica (CRG) @crg.eu · 06/07/2026
Catalan centers and universities obtain 14 out of the 29 ERC Advance grants awarded in Spain this year, including a record 4th consecutive one for the CRG's Luis Serrano. Here's a deep dive in @ara.cat
en.ara.cat
Catalonia plays in the European research Champions League
Catalan centers and universities obtain 14 of the 29 grants awarded in Spain. Luis Serrano chains a fourth consecutive Advanced Grant and Eduard Batlle, a third
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Young PI Neuroscience Symposium'26 @young-pi-neuro26.bsky.social · 05/07/2026
Here we go!
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Adriano Bolondi @adrianobolondi.bsky.social · 04/07/2026
We at @crg.eu and @prbb.org are very much looking forward to host this vibrant community! A great day of science and reflection ahead!
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Silvia Viana da Silva @silviaviansilva.bsky.social · 04/07/2026
On my way✈️
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Matthew L. Kraushar @matthewkraushar.bsky.social · 04/07/2026
Hola 👋 On my way ✈️ Looking forward to seeing you there
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Nikos Konstantinides @nkonst4.bsky.social · 04/07/2026
So much looking forward to this!
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Young PI Neuroscience Symposium'26 @young-pi-neuro26.bsky.social · 04/07/2026
Our @fens.org Satellite meeting is tomorrow! #FENS2026 Check out our updated program👇 youngpisymposium2026.com/program/ We are all super excited to have everyone joining! Safe travels everyone 🚅 ✈️ 🚲 See you in Barcelona 🔆😎
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Christopher Thomas @ovarylab.bsky.social · 20/04/2026
How does an ovarian follicle remodel in space and time to release an egg? 💥🥚 We have an exciting PhD project combining follicle culture, advanced imaging and quantitative analysis to understand the cellular dynamics of ovulation. 🔬 Co-supervised by me and @guignardlab.bsky.social. Please share! 🌱
An ovarian follicle poised for ovulation, with the oocyte at its centre. Cell membranes are shown in orange and DNA in blue.
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Matthew L. Kraushar @matthewkraushar.bsky.social · 16/06/2026
Let's step inside a neuron together, and ask, "how did all this get here?" 🤔 In this review, I trace the history and transformations of a neuron's molecules, pay homage to major discoveries in brain development ... and make a call to action for neuroscience. www.annualreviews.org/content/jour...
annualreviews.org
The Translation of Genetic Information in Neurodevelopment
Neurodevelopment is the transformation of genetic information into diverse neuronal phenotypes. Developmental signals initiate patterns of gene transcription and translation that drive progenitors tow...
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Cedric Feschotte @cedricfeschotte.bsky.social · 29/05/2026
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com
thefeschottelabatcornell.com
The Feschotte Lab at Cornell
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Aydan Bulut-Karslioglu @bulutkarslioglu.bsky.social · 03/05/2026
Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...
biorxiv.org
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Meng Zhu @zhumeng123.bsky.social · 30/04/2026
Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩
mzhulab.com
Meng Zhu Lab
We study how development measures time and how timing matters in development, evolution and ageing.
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Daniel MK Lee @dannimklee.bsky.social · 24/04/2026
New Preprint alert!🚨 Super excited to share my postdoc work now on BioRxiv. How does PRC2 loss lead to developmental failures? We combined rapid protein degradation with TLS embryoid models to uncover temporal and lineage-specific dependencies 🧬. Preprint: doi.org/10.64898/2026.04.18.719361
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 16/04/2026
A new study shows how different regulatory genetic elements control when a key developmental gene is active in the body. The findings could explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown.
lms.mrc.ac.uk
Waves of regulation control an important developmental gene
In a new study published in Genes & Development, research led by Dr Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for Mo...
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FMI science @fmiscience.bsky.social · 15/04/2026
In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv. www.fmi.ch/news-events/...
fmi.ch
Curiosity, cell clearance, and improv: A chat with Julia Batki
In this interview, Julia Batki, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us un...
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Jesse Veenvliet @jesseveenvliet.bsky.social · 09/04/2026
📣 New Perspective out in @natcellbio.nature.com! With an interdisciplinary team of scientists, ethicists & lawyer we propose embedded ethics as a framework for navigating the complex ethics of human stem cell–based embryo models. www.nature.com/articles/s41... Free full text link: rdcu.be/fckmY 🧵
nature.com
A guide to using embedded ethics in human stem-cell-based embryo model research - Nature Cell Biology
This Perspective proposes the use of an integrative embedded ethics approach to evaluate human stem-cell-based embryo models and outlines a nested benchmarking strategy to periodically evaluate their scientific and ethical status.
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canaztekin.bsky.social @canaztekin.bsky.social · 10/04/2026
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo
science.org
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...
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Adriano Bolondi @adrianobolondi.bsky.social · 08/04/2026
Honored to receive a La Caixa Junior Leader Fellowship @caixaresearch.bsky.social at @crg.eu. This recognition will support our research on oocyte dormancy and proteostasis for the next three years🥚! Big thanks to previous funders @embo.org & MSCA @ec.europa.eu and to @bokelab.bsky.social @prbb.org!
La Caixa Foundation Award Ceremony 2026 - Barcelona
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Miquel Anglada-Girotto @m1quelag.bsky.social · 01/04/2026
Many regulatory layers modulate splicing factors at the same time impacting their activity. How can we quantify it? Apparently "functional" target exons give us a hint and uncover two cancer programs. Have a look at our solution: www.nature.com/articles/s41...
nature.com
Exon inclusion signatures enable accurate estimation of splicing factor activity - Nature Communications
Splicing factors shape how genes are stitched into RNA, but their activity is hard to measure. Here, the authors benchmark network methods and show exon-inclusion signatures infer splicing factor acti...
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Joshua Frenster @joshifrenster.bsky.social · 01/04/2026
🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...
nature.com
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
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Jesse Veenvliet @jesseveenvliet.bsky.social · 25/03/2026
🎉 Very happy, stoked & honored to have been awarded an @hfspo.bsky.social Research Program Grant for a dream project conceived w/ Eric Glowacki @ceitec.eu & @bernasozen.bsky.social 🥳 Thanks @hfspo.bsky.social for funding bold ideas & projects that aim to push across boundaries 🙏 #stuffthatmatters
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Adriano Bolondi @adrianobolondi.bsky.social · 05/03/2026
🚨JOB ALERT🚨PLEASE SPREAD and RT Searching for a motivated Master’s student @bokelab.bsky.social @crg.eu @prbb.org to investigate how proteostasis in oocytes influences dormancy and fertility. Reach out to me (adriano.bolondi@crg.es) to join us in sunny Barcelona! See details below👇
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Adriano Bolondi @adrianobolondi.bsky.social · 30/03/2026
Tomorrow will be the last day to apply! Send your applications to join us!
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Giselle Cheung @giselletycheung.bsky.social · 24/03/2026
🧠 There’s still time to register👇 and join the YPI community for a full day of neuroscience, skills, trainings, strategies, discussions, networking and resilience building - by the beach 🏖️! @fens.org satellite event! youngpisymposium2026.com
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Gioele La Manno @gioelelamanno.bsky.social · 24/03/2026
Thrilled to receive the 2026 Boehringer Ingelheim FENS Research Award. Exciting to see our work on brain development recognized by the European neuroscience community. Grateful to my mentors, my lab, and my family. Award lecture at FENS Forum Barcelona in July! www.fens.org/news-activit...
fens.org
Winner of the Boehringer Ingelheim FENS Research Award 2026 announced - Federation of European Neuroscience Societies
The Federation of European Neuroscience Societies (FENS) and Boehringer Ingelheim are delighted to announce the recipient of the Boehringer Ingelheim FENS Research Award 2026: Gioele La Manno.
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Adriano Bolondi @adrianobolondi.bsky.social · 20/03/2026
12 days left to apply! @bokelab.bsky.social @crg.eu @prbb.org See here: recruitment.crg.eu/content/jobs...
recruitment.crg.eu
Master’s Student position in Oocyte Biology and Cellular Dormancy | CRG Online Recruitment Portal
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Jesse Veenvliet @jesseveenvliet.bsky.social · 18/03/2026
With the human embryo model field rapidly expanding, it would be good if those venturing into it properly acknowledge the history of the field and give credit where credit's due. I doubt hTLS would be there w/o mouse gastruloids @amartinezarias.bsky.social @susannevandenbrink.bsky.social & TLS.
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Jesse Veenvliet @jesseveenvliet.bsky.social · 18/03/2026
This is now the 2nd human trunk-like-structure (TLS) paper in a row that fails to cite our work @adrianobolondi.bsky.social, which demonstrated the first TLS (mouse). Especially striking since the preprint studies (a.o.) the TBX6-KO phenotype, which we used as a proof-of-concept in mouse TLS (1/2)
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Ivano Legnini @ilegnini.bsky.social · 11/03/2026
Happy 🥲 We're now looking for a postdoc and a technician to work on this super exciting 5 years project on mRNA mtabolism and poly(A) tail length control. Links to apply here: Postdoc: careers.humantechnopole.it/job/Postdoc-... Technician: careers.humantechnopole.it/job/Technici...
careers.humantechnopole.it
Postdoc Legnini Lab (FIS3 POLARIS project)
Postdoc Legnini Lab (FIS3 POLARIS project)
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Adriano Bolondi @adrianobolondi.bsky.social · 09/03/2026
Three more weeks to apply and join us in Barcelona! Help us understanding how oocytes regulate proteostasis and fertility! Find here more detailed information on the call: recruitment.crg.eu/content/jobs... Please spread around your communities!
recruitment.crg.eu
Master’s Student position in Oocyte Biology and Cellular Dormancy | CRG Online Recruitment Portal
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Young PI Neuroscience Symposium'26 @young-pi-neuro26.bsky.social · 06/03/2026
Today we present another of our amazing speakers: @anne-schreiter.bsky.social the executive director from @gso-forresearchers.bsky.social. She will give us an interactive workshop about Leadership and Team-building. Register to our @fens.org Satellite 👉 youngpisymposium2026.com
youngpisymposium2026.com
Young PI Symposium 2026
Visit the post for more.
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Darío Lupiáñez @dariloops.bsky.social · 06/03/2026
🚨 Job Alert - Please share! 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! We’re recruiting: ✅ PhD students ✅ Postdocs 💻🧪 Experimental or computational backgrounds welcome 👇 Details below
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Adriano Bolondi @adrianobolondi.bsky.social · 05/03/2026
🚨JOB ALERT🚨PLEASE SPREAD and RT Searching for a motivated Master’s student @bokelab.bsky.social @crg.eu @prbb.org to investigate how proteostasis in oocytes influences dormancy and fertility. Reach out to me (adriano.bolondi@crg.es) to join us in sunny Barcelona! See details below👇
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ISSCR @isscr.org · 03/03/2026
The ISSCR is pleased to announce that Alexander Meissner, Director of Max Planck Institute for Molecular Genetics, Germany, has been named the recipient of the 2026 ISSCR Momentum Award, supported by BlueRock Therapeutics! Learn more: ow.ly/eUNt50YoFm3
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Young PI Neuroscience Symposium'26 @young-pi-neuro26.bsky.social · 03/03/2026
Deadline extended until end of March! Join our @fens.org Satellite 👉 youngpisymposium2026.com
youngpisymposium2026.com
Young PI Symposium 2026
Visit the post for more.
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Carlos Pérez-González @cperez-gonzalez.bsky.social · 24/02/2026
Interested in doing a PhD in tumor mechanobiology? At Université Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab. If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!
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