iiinova — where your digital self keeps evolving

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Keri Martinowich @martinowk.bsky.social · 07/10/2026

Really enjoyed getting to have @brainevodevo.bsky.social visit with us @lieberinstitute.bsky.social today to talk about work from his team on perturbational genomics of human 🧠 evolution, and meet with our students, fellows and investigators to talk about so many shared research interests.

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 22/09/2026

140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 07 summary lcolladotor.github.io/jhustatcompu... Guest speaker: @nick-eagles.bsky.social from @lieberinstitute.bsky.social #RStats #DataScience #PositAssistant #AIcoding #Claude

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 14/09/2026

We are excited to host @areal25.bsky.social at @lieberinstitute.bsky.social In prep, my team did a journal club on the #BigBrain project preprint "Mapping genetic effects on splicing [...]" doi.org/10.1101/2025... from the @trajnp.bsky.social & @davidaknowles.bsky.social labs youtu.be/iVyVcAgPZW8

youtu.be

[2026-09-02] Journal club on "Mapping genetic effects on splicing [...]" aka BigBrain project

YouTube video by Leonardo Collado Torres

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Bernie Mulvey @berniejmulvey.bsky.social · 11/09/2026

Excited to share work with cryostat wizard @heenadivecha.bsky.social looking at gene expression in my favorite brain region (LC) in adult postmortem brain! (Long URL to spare the trouble of identifying cars, buses, beds in 5x5 pixel imgs). (1/x) link.springer.com/epdf/10.1007...

link.springer.com

Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability

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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 11/09/2026

A little bit of what we are doing in the circuits group at @lieberinstitute.bsky.social. An Amphetamine recruited ensemble in the mPFC tagged with mCherry. Credits to Suhaas Adiraju (Grad student) and @danolivares.bsky.social. #fluorescencefriday

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Keri Martinowich @martinowk.bsky.social · 04/09/2026

For #FluorescenceFriday - some pretty human iPSC-derived neural progenitor cells being differentiated into a hindbrain fate. SOX2 in aqua, GBX2 in yellow and TH in magenta. Image credit to the Imaging Development team @lieberinstitute.bsky.social 🔬🧠

Fluorescence microscopy of human neural progenitor cells in culture stained for markers of cell types in blue, yellow and magenta

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Keri Martinowich @martinowk.bsky.social · 28/08/2026

For #FluorescenceFriday - me snooping recent server uploads - don't even know what the experiment is, but guessing its cortical neurons projecting to locus coeruleus. Whatever it is, looks pretty amazing 🤩🔬🧠. Image credit to @danolivares.bsky.social on the @lieberinstitute.bsky.social Circuits team!

Fluorescence micrograph of virally labeled green neurons in a tissue section of mouse cortex (I think)

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Simon Fisher @profsimonfisher.bsky.social · 19/08/2026

Very excited for our new project on molecular & cellular properties of language circuits, & greatly appreciate this opportunity to collaborate with @martinowk.bsky.social & @lieberinstitute.bsky.social colleagues, pioneers in neural transcriptomics.

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Keri Martinowich @martinowk.bsky.social · 19/08/2026

Super excited to have @gokberkalagoz.bsky.social joining our teams @lieberinstitute.bsky.social as a Visiting Scientist for a few months to work on a collaborative project with @profsimonfisher.bsky.social lab on a cross species spatial transcriptomics project related to language processing.

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Vinny Costa @vincentcostaphd.bsky.social · 28/08/2026

Like I have mentioned before spatial neurobiology is very hard. @svitlanabach.bsky.social makes the impossible seem routine.

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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 14/08/2026

Coming back from another amazing GRC frontal cortex. So proud of Suhaas Adiraju who presented some of the work we are doing at @lieberinstitute.bsky.social about Amphetamine ensembles within the mPFC.

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Keri Martinowich @martinowk.bsky.social · 12/08/2026

With expansion of several stem cell based initiatives @lieberinstitute.bsky.social - we are hiring! We are looking for a Staff Scientist with expertise in hiPSCs and iPSC-derived neuronal models to join our Stem Cell Core, directed by @tsawada1.bsky.social recruiting.paylocity.com/recruiting/j...

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Stephanie Staszko @sstaszko.bsky.social · 30/07/2026

Studying norepinephrine? Have cool results to share? Want to join an online community of norepinephrine researchers? We are organizing our fall schedule for the Blue Spot Slack! We have monthly virtual seminars where you can share your work and get feedback in a supportive environment. Apply/join ⬇️

Immunohistochemical staining showing noradrenergic neurons of the locus coeruleus

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Olivia Drake @odrake.bsky.social · 30/07/2026

Our new preprint from @daylab.bsky.social characterizes Chst9-MSNs, a specialized NAc population with high Oprm1 expression and opioid sensitivity that is required for fentanyl reward learning. Excited to share this work! 🧠🧬 www.biorxiv.org/content/10.6...

biorxiv.org

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Keri Martinowich @martinowk.bsky.social · 31/07/2026

Congratulations @robinmagnard.bsky.social @daiannaglez.bsky.social and everyone involved from @kr-maynard.bsky.social @triciajanak.bsky.social @lcolladotor.bsky.social teams! Excited to see you all get this paper published and excited for the next steps and follow up studies!

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Keri Martinowich @martinowk.bsky.social · 31/07/2026

Congrats @jorge-miranda.bsky.social! I'm so excited for you and proud of all you have accomplished since joining @lieberinstitute.bsky.social - we are lucky to have you and your collaborative spirit on our teams! Also, what's with all the lab good news? Maybe I should go on vacay more often ;)

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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 30/07/2026

I am so thrilled to share that i was selected to received the 2026 BBRF young investigator grant from the @bbrfoundation.bsky.social. This is meaningful for me. Thanks so much to @martinowk.bsky.social and the @lieberinstitute.bsky.social for all the support.

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Robin Magnard @robinmagnard.bsky.social · 30/07/2026

🧠🧬 What are the effects of intravenous fentanyl self-administration on the habenula and amygdala transcriptomes? In our new Addiction Biology paper, we addressed this question using a chronic long-access model in rats! Here are some highlights 🧵👇 Paper 👉 dx.doi.org/10.1111/adb....

dx.doi.org

Transcriptional Response to Chronic Long‐Access Fentanyl Self‐Administration in Rat Habenula and Amygdala

Chronic intravenous long-access fentanyl self-administration in rats produced transcriptional remodeling in the habenula and amygdala. Bulk RNA-sequencing identified 453 habenula and 3,041 amygdala d...

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Keri Martinowich @martinowk.bsky.social · 10/07/2026

For #FluorescenceFriday - human induced pluripotent stem cells trying to differentiate into locus coeruleus-like neurons... pretty pink one on their way and stained for tyrosine hydroxylase 🔬🤩🧠. Image credits to @lieberinstitute.bsky.social Stem Cell core and Imaging Development team. So excited!

Microscopy image of cells in a dish that are stained different colors for cell type markers

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Keri Martinowich @martinowk.bsky.social · 16/07/2026

Was HOT 🌞 yesterday for long standing @lieberinstitute.bsky.social annual 🦀 feast tradition. Thanks to everyone on our teams who came out to celebrate another year of accomplishments, community and great science!

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Prashanthi Ravichandran @prashanthi-ravi.bsky.social · 02/07/2026

(1/10) We’re excited to share our recently published study www.sciencedirect.com/science/arti... which uncovers the spatiomolecular landscape of the human NAc, a key reward structure by integrating snRNA-seq with Visium spatial transcriptomics. 🧠 #NAcLIBD #snRNAseq #10xVisium

sciencedirect.com

Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

The nucleus accumbens (NAc) is a key component of the mesolimbic dopamine system that is implicated in several neuropsychiatric disorders. The NAc con…

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Kristen Maynard @kr-maynard.bsky.social · 02/07/2026

Excited to share our new study characterizing spatial gene expression in the human NAc led by @prashanthi-ravi.bsky.social @svitlanabach.bsky.social @rphillips3.bsky.social in collaboration with @martinowk.bsky.social @stephaniehicks.bsky.social @alexisbattle.bsky.social @lcolladotor.bsky.social.

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Keri Martinowich @martinowk.bsky.social · 16/06/2026

Thanks @vincentcostaphd.bsky.social - truly appreciate the respect for what our teams @lieberinstitute.bsky.social are doing on the spatial data generation front - they're amazing. I can't take the credit, so I'm going to use this as an excuse to give a shout out to the people running that engine.

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Keri Martinowich @martinowk.bsky.social · 10/06/2026

Was stoked to host @debbysilver.bsky.social at @lieberinstitute.bsky.social today! Fantastic talk on her lab's work on molecular features that make the human 🧠 unique and how RNA localization shapes early neurodevelopment. Great conversations + exciting ideas for future collaborations - thx Debby!

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/06/2026

New team photos! 2026 version with @mbarse.bsky.social, @lahuuki.bsky.social, @nick-eagles.bsky.social ^^. We also have remote member contributors 🗺️ (@daiannaglez.bsky.social, @melo-mq99.bsky.social, @gabrielramirezv.bsky.social, from LCG UNAM). Thank you @martinowk.bsky.social for hosting us!

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Keri Martinowich @martinowk.bsky.social · 29/05/2026

For #FluorescenceFriday, highlighting exploration of a brand new region for us in the human 🧠 - BA11, orbitofrontal cortex. The laminar structure across the gyrification here is really just amazing to look at. Image credit to RA Shreya Joshy in Stephanie Page's group @lieberinstitute.bsky.social

Fluorescence microscopy image of a section of human brain tissue in the orbitofrontal cortex with different layers of the cortical structure labeled in red, yellow and purple and the white matter in green.

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Robin Magnard @robinmagnard.bsky.social · 15/05/2026

Thrilled about our new @janaklab.bsky.social paper now out in @npp-journal.bsky.social🧠⚡ Action-sequence termination cues evoke mesolimbic dopamine activity that drives habit-like behavior. Thanks to Tricia Janak, @younavandaele.bsky.social, and @yfcheng.bsky.social! www.nature.com/articles/s41...

nature.com

Sequence termination cues drive automated habit-like strategy via dopamine-mediated processes - Neuropsychopharmacology

Neuropsychopharmacology - Sequence termination cues drive automated habit-like strategy via dopamine-mediated processes

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Keri Martinowich @martinowk.bsky.social · 18/05/2026

Made it to Montreal for #CAN2026 @canacn.bsky.social after a road-trip adventure :) Excited to be sharing work from our @lieberinstitute.bsky.social teams at the meeting - today at @theneuro.bsky.social to participate in the spatial transcriptomics pre-mtg satellite 🔬🧠👩‍🔬

Keri in the atrium of The Neuro at McGill

Spatial transcriptomics satellite meeting at the Canadian Neuroscience meeting

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Molly Schumer @mollyschumer.bsky.social · 08/05/2026

@gpreising.bsky.social is a long read rock star and is looking for postdocs or industry positions! bsky.app/profile/lcol...

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 08/05/2026

Megan D. Schertzer from @davidaknowles.bsky.social’s lab invites us to use « perplexity » from Ecology to measure isoform diversity (or other molecular units). Very thought provoking! 🤔 More at doi.org/10.1101/2025... #BoG2026 @cshlmeetings.bsky.social

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 07/05/2026

Boxiang @boxiangliu.bsky.social showcased #ISAAC for computing splicing QTLs #sQTLs using single cell data They applied it to DLPFC 🧠 data from 722 donors github.com/boxiangliula... #BoG2026 @cshlmeetings.bsky.social

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 07/05/2026

Did you miss #BoG2026 or want to share your work or want to keep learning about great computational biology? Mike @mikeschatz.bsky.social invites us to #BDS26 later this year in November Check bit.ly/cshl-biodata26 for all the details! @cshlmeetings.bsky.social

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 07/05/2026

Mike @mikeschatz.bsky.social paid tribute to James P. Taylor who was one of the main champions of #OpenScience @jxtxfoundation.bsky.social carries on. Mike introduced the winners of the scholarship to attend #BoG2026 this year (sponsored by @pacbio.bsky.social this yr) 👏🏽 @cshlmeetings.bsky.social

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/05/2026

Lifan Liang is going beyond eQTL to study brain 🧠 disorders Lots of single cell multiomic data from human iPSC-derived neurons. Leads to many chromatic accessibility (ca)QTLs upon neuron stimulation. Could help interpret non-coding 🧬 variation in 🧠 #BoG2026 @cshlmeetings.bsky.social

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/05/2026

Sasha @sashagusevposts.bsky.social (author of #FUSION-TWAS and much more) gets the honor of starting day 2 of #BoG2026 @cshlmeetings.bsky.social Time to think about genetics 🧬, statistics, common variants, et al related to complex disorders

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/05/2026

Yoav @ygilad.bsky.social kickstarts #BoG2026 at @cshlmeetings.bsky.social by asking us to be open minded and think beyond biology defined by means. To think about the dispersion / variance.

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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 24/04/2026

Yesterday I had the privilege to give a virtual talk to undergrad and graduate students in Mexico about some of our work at @lieberinstitute.bsky.social. It was great to connect with the community, and giving it in spanish felt so special. #cienciaenespañol!

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Keri Martinowich @martinowk.bsky.social · 17/04/2026

For #FluorescenceFriday, labeled neurons in the mouse frontal cortex (vague as all get out just for @markgbaxter.bsky.social 😉) that project to the ventral tegmental area. Image credit to RA Daniel Olivares on the Circuits team @lieberinstitute.bsky.social 🔬🧠

Fluorescence microscopy image showing neurons virally labeled in red in a slice of mouse brain tissue at the level of the frontal cortex that are projecting to the ventral tegmental area

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Centro de Neurociencias Cajal @cncajal-csic.bsky.social · 22/04/2026

🧠 CNC Scientific Seminar 📆 April 27 | 12:30 PM 👉 Dr. Evgeny Shlevkov(@lieberinstitute.bsky.social @jhu.edu ) 🎙️ “Genetics to Therapeutics: Mapping Druggable Mechanisms in Brain Disorders ” ⚡️ Organized by: TP-1 Organoids 📍 CNC, Alcalá de Henares (Madrid)

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The Friedman Brain Institute @sinaibrain.bsky.social · 31/03/2026

PRESS RELEASE! Study, co-led by Michael S. Breen & Joseph Buxbaum, in collab w @lieberinstitute.bsky.social, Medical University of Sofia & @uarizona.bsky.social, has ID'd biological process that may help explain how brain develops diff in people w #DownSyndrome. 👉 www.mountsinai.org/about/newsro...

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Jenn Kim @drjennkim.bsky.social · 26/03/2026

@libdrstats.bsky.social videos and blog posts continue to be a great resource for me as I delve into snRNAseq analyses, and for lots of other bioinformatics-related topics! Learn more here: research.libd.org/rstatsclub/

research.libd.org

LIBD rstats club

Continuous rstats learning

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Jenn Kim @drjennkim.bsky.social · 26/03/2026

Check out my first @libdrstats.bsky.social presentation on one strategy our team @lcolladotor.bsky.social at @lieberinstitute.bsky.social is taking to deal with doublets during quality control for single nucleus RNA-sequencing data: www.youtube.com/watch?v=SMA-...

youtube.com

[2026-02-27] Strategy to drop doublets during snRNAseq QC steps

YouTube video by Leonardo Collado Torres

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 05/03/2026

Thanks to all my @lieberinstitute.bsky.social and external colleagues who helped me with my first 🇺🇸 National Institutes of Health (NIH) R01 grant resubmission ^^ and those who wrote support letters for it Hopefully it’ll do well on this second round! Fingers crossed 🤞🏽 #ESI

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 20/02/2026

Talk submission video for Posit Conf 2026 #RStats «Organizing your data science team to be efficient, adaptive to new developments, and resilient to turnover rate» URLs: 1. lcolladotor.github.io/bioc_team_ds/ 2. research.libd.org/rstatsclub/ 3. github.com/LieberInstit... #OpenSource #Bioconductor

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Keri Martinowich @martinowk.bsky.social · 20/02/2026

New postdoctoral opportunity @lieberinstitute.bsky.social working w/ @tsawada1.bsky.social and our Molecular Neurogenetics team using human induced pluripotent stem cells to investigate molecular, cellular and neuroendocrine mechanisms by which impaired placental function impacts brain development

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Sang Ho (Sangho) Kwon @shkwon-bcmbneuro.bsky.social · 18/02/2026

We sincerely thank #NIMH #NIGMS & @lieberinstitute.bsky.social for supporting this work and are deeply grateful to the donors and their families, whose generosity made this research possible. Again, we’re very excited to share this work with the community and look forward what comes next 🤩 (9/9)

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Sang Ho (Sangho) Kwon @shkwon-bcmbneuro.bsky.social · 18/02/2026

FIRST post here on Bluesky - we’re excited to share that our large spatial transcriptomics study of the human dlPFC in schizophrenia is now available on bioRxiv📄: www.biorxiv.org/content/10.6... (1/9)

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Keri Martinowich @martinowk.bsky.social · 06/02/2026

For #FluorescenceFriday - unmistakably the blue spot 🔵 (locus coeruleus) - here labeled in a section of the mouse brain in pink with tyrosine hydroxylase (TH) 🔬🧠🧪 Image credit to the @lieberinstitute.bsky.social Circuits team - @jorge-miranda.bsky.social @rehg-j.bsky.social

Microscopy image showing pink fill in neurons stained for tyrosine hydroxylase in a section of mouse brain tissue

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