Reposted by MRC-LMB Cell Biology DivisionStefano Giandomenico @sgiando.bsky.social · 30/09/2026Can a brain organoid grown in a dish build synapses that resemble the real thing at the molecular level? 🧠 We grew mouse forebrain organoids for 35 days and compared their synaptic proteome to that of the adult mouse cortex 🧪 www.biorxiv.org/content/10.6... 🧵 1/5 12111
Reposted by MRC-LMB Cell Biology DivisionMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 01/10/2026Interested in cerebral organoids? 🧠 Don’t miss the latest episode of Unexpected Elements from BBC World Service, featuring @apadonovan.bsky.social, Postdooctoral Fellow in @lancasterlab.bsky.social’s group in @cellbiol-mrclmb.bsky.social. Catch it here: www.bbc.co.uk/sounds/play/... #LMBintheNewsbbc.co.ukUnexpected Elements - An identity crisis - BBC SoundsA case of mistaken identity inspires us to explore the science of getting things wrong. 051
Reposted by MRC-LMB Cell Biology DivisionMatthew Freeman @mjafreeman.bsky.social · 30/09/2026Yet another opportunity @dunnschool.bsky.social! We are looking for an Associate Professor If you have exciting research plans, @dunnschool.bsky.social is a great place: excellent science (and lovely people, obvs) www.path.ox.ac.uk/vacancy/asso...path.ox.ac.ukAssociate Professorship of Cancer Biology - Sir William Dunn School of Pathology in association with the Queen’s College. - Dunn SchoolWe are seeking to appoint an Associate Professor working in the area of the cellular and/or molecular biology of cancer, to be based in Oxford University’s Sir William Dunn School of Pathology. The ro... 01828
Reposted by MRC-LMB Cell Biology DivisionMathilda Lennartz @mathilda95.bsky.social · 30/09/2026UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....nature.comQuantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell BiologyLennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ... 711246
Reposted by MRC-LMB Cell Biology DivisionJez Carlton @jezcarlton.bsky.social · 28/09/2026Hey! Submit your papers, and spread the word, this will be great! Thanks for inviting us @jcellsci.bsky.social and great to work with @pihanson.bsky.social on this issue! 02324
Reposted by MRC-LMB Cell Biology DivisionBuzz Baum @buzzbaum.bsky.social · 22/09/2026We are looking for a research assistant! Come join the team: www.jobs.ac.uk/job/DSZ826/r...jobs.ac.ukResearch Support Officer | Cell Biology | Dr Buzz Baum | LMB 2904 at MRC Laboratory of Molecular BiologyStart your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top... 02846
Reposted by MRC-LMB Cell Biology DivisionMartin Pacesa @martinpacesa.bsky.social · 21/09/2026ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi... 4292142
Reposted by MRC-LMB Cell Biology DivisionFelix Campelo @felixmendu.bsky.social · 16/09/2026This is tomorrow (thursday, 5pm CET)! Join us for the first session of the #membranetrafficking seminars after the break :) 055
Reposted by MRC-LMB Cell Biology DivisionMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 16/09/2026How do cells remove abnormal glycogen? Led by Matthew Yip, using mouse models, cell engineering & cryo-ET, Felix Randow's group found that RNF213 ubiquitylates aberrant glycogen to trigger autophagy. mrclmb.ac.uk/news-events/articles/h… #LMBResearch 03017
Reposted by MRC-LMB Cell Biology DivisionIn Preparation @inprep.bsky.social · 15/09/2026inpreparation.substack.comHHMI Launches Initiative To Support Scientists Who Attended Second-Tier IviesCHEVY CHASE, MD—In a landmark effort to expand opportunity in the biomedical sciences, the Howard Hughes Medical Institute announced Tuesday a new $200 million initiative to support scientists from… 2142
Reposted by MRC-LMB Cell Biology DivisionCell Biology J-Club @cellclub.bsky.social · 15/09/2026New on CLN8 - a previously defined ER-cargo receptor: The Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis www.nature.com/articles/s41...nature.comThe Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis - Nature Cell BiologyTwo studies show that the endoplasmic reticulum-associated protein CLN8 catalyses the acyl CoA-dependent acylation of glycerophosphoglycerol, producing lysophosphatidylglycerol, which is then converte... 063
Reposted by MRC-LMB Cell Biology DivisionSjors Scheres @sjorsscheres.bsky.social · 15/09/2026Michel Goedert and myself are looking for two postdocs to work on #cryoEM and #masspec of #alphasynuclein filaments from neurodegenerative disease. Come join our bubbly and friendly team at the @mrclmb.ac.uk in lovely Cambridge, UK. www.nature.com/naturecareer...nature.comPostdoctoral Scientist | Neurobiology | Dr Michel Goedert | LMB 2842 - Cambridgeshire job with MRC Laboratory of Molecular Biology | 12864505Postdoctoral Scientist Salary £42,694 per annum Fixed term, 3 years MRC Laboratory of Molecular Biology, Cambridge, UK To work in the group of Dr M... 01628
Reposted by MRC-LMB Cell Biology DivisionAlex Ludwig @alexludwig.bsky.social · 14/09/2026How do epithelial cells make a lumen as they polarize? We have some exciting new answers to this long standing question. Check out our new paper in which we show that lumen initiation is driven by large vacuoles that deliver a pre-assembled apical cortex to the AMIS: www.nature.com/articles/s41...nature.comBulk delivery of a preassembled apical surface initiates epithelial lumen formation - Nature CommunicationsEpithelial lumen formation is fundamental to organ development, yet how apical surfaces first emerge remains unclear. Ghosh, Martin, and Chen et al., show that lumen initiation is driven via bulk deli... 03312
Reposted by MRC-LMB Cell Biology DivisionMarta Shahbazi @marta-shahbazi.bsky.social · 11/09/2026Really happy and honoured! Thank you so much! 8627
Reposted by MRC-LMB Cell Biology DivisionMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 11/09/2026Ready to take the next step in your research career? The LMB is now accepting applications for PhD placements starting in October 2027. Deadline: 08 December 2026 (allow time for reference submission). Discover what we offer here: mrclmb.ac.uk/careers-and-people/phd… 034
Reposted by MRC-LMB Cell Biology DivisionAlex von Tunzelmann @alexvont.bsky.social · 10/09/2026If you feel like donating to the RNLI, here’s a link. I just have. Their minimum donation is £2: I think it might be nice for them to receive a lot of donations this week, even if they’re mostly very modest. Just so they know a lot of people out here appreciate their work. rnli.org/support-us/g...rnli.orgDonate to the RNLI and help save lives at seaYour donations really make a difference. We depend on your generosity to educate people to stay safe and prevent tragedies on and offshore. Donate here. 4920921254
Reposted by MRC-LMB Cell Biology DivisionMatthew Freeman @mjafreeman.bsky.social · 08/09/2026Feels like an interesting one... oh, wait...! 0145
Reposted by MRC-LMB Cell Biology DivisionAntoine Molaro @antoinemolaro.bsky.social · 09/09/2026Hello World ! Reminder about our open postdoc position 🧪🧬 Reviewing applications until October - get in touch to know more about what's hot in the lab these days ! Application details in the post below 👇👇 #EvoEpi #MolaroLab #watwat #ERC 0416
Reposted by MRC-LMB Cell Biology DivisionPedro Beltrao @pedrobeltrao.bsky.social · 09/09/2026I made a presentation to other faculty about recent progress in general AI, to facilitate the discussion around the impact for research and teaching in biology. It could be that the slides are useful for others trying to do that same. Feel free to re-use. docs.google.com/presentation...docs.google.comgeneralAI_for research_intro.pptxRecent AI developments and what they mean for us Quick primer on general AI models* State-of-the-art in AI agent capabilities AI agents in biology (examples) Discussion - what does this mean for our r... 79026
Reposted by MRC-LMB Cell Biology DivisionCell Biology J-Club @cellclub.bsky.social · 08/09/2026The rhomboid-like pseudoprotease TMEM115 defines a two-factor mechanism for Rab6A effector recruitment www.biorxiv.org/content/10.6...biorxiv.orgThe rhomboid-like pseudoprotease TMEM115 defines a two-factor mechanism for Rab6A effector recruitmentProtein trafficking and organelle identity depends on precise localisation of membrane proteins, anchored by small GTPases that bind to specific cellular compartments. Here we show that the rhomboid-l... 062
Reposted by MRC-LMB Cell Biology DivisionbioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 08/09/2026The rhomboid-like pseudoprotease TMEM115 defines a two-factor mechanism for Rab6A effector recruitment www.biorxiv.org/content/10.64898/20… 032
Reposted by MRC-LMB Cell Biology DivisionJournal of Cell Biology @jcb.org · 07/09/2026Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis. From Samantha K. Dziurdzik, Vaishnavi Sridhar, @lizconibear.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode 053
Reposted by MRC-LMB Cell Biology DivisionIshier Raote @ishier.bsky.social · 07/09/2026Membrane Trafficking Seminar Series 2026 fall season is here! An exciting programme: membrane traffic, organelle biogenesis, lipid transport, endomembrane evolution, we have it all! Save the dates and join us for fun science and discussions. Details at felixcampelo.wixsite.com/membranetraf... 22725
Reposted by MRC-LMB Cell Biology DivisionJournal of Cell Biology @jcb.org · 07/09/2026The cell biologist’s guide to detecting and modulating membrane #phospholipids. A review by Worcester, @gerryhammond.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode 01611
Reposted by MRC-LMB Cell Biology DivisionMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 03/09/2026The complete #connectome of the adult Drosophila male CNS has allowed researchers, inc @jefferis.bsky.social’s group, to compare male & female brains at synaptic-resolution for the first time. Read more here: mrclmb.ac.uk/news-events/... #LMBResearch 1/2 18129
Reposted by MRC-LMB Cell Biology DivisionFlyBase @flybase.bsky.social · 02/09/2026As you may know, NIH abruptly terminated funding to FlyBase curators based in the United Kingdom. Please help us retain these curators and thereby enable ongoing curation of bibliographic, genetic and phenotypic data by contributing annually (tinyurl.com/4jw65mbb). Thank you. #FlyBasetinyurl.comFlyBase:Contribute to FlyBase - FlyBase Wiki 02723
Reposted by MRC-LMB Cell Biology DivisionThe EMBO Journal @embojournal.org · 25/08/2026How are perforin-2 immune functions in attacking bacteria & in antigen cross-presentation coordinated? @patrycja-kozik.bsky.social et al find its extensive proteolytic processing, but antigen trafficking in dendritic cells selectively requires the full-length form link.springer.com/article/10.1...link.springer.comAnchoring of perforin-2 via the transmembrane domain is required for antigen escape into the cytosol - The EMBO JournalPerforin-2 is a pore-forming protein localised to the endocytic compartments of dendritic cells and macrophages. It is reported to perform two distinct functions during immune responses: attacking int... 043
Reposted by MRC-LMB Cell Biology DivisionRobert Arkowitz @robertarkowitz.bsky.social · 01/09/2026🔬🧪🦠 An exciting opportunity to work at the interface of Fungal Cell Biology & Biophysics in Nice, FR in a collaborative project on roles of cytoplasmic crowding in fungal pathogen morphogenesis, antifungal responses and host interaction. ibv.unice.fr/news/postdoc... Please share/retweet 2713
MRC-LMB Cell Biology Division @cellbiol-mrclmb.bsky.social · 28/08/2026Great tribute to the discovery by Barbara Pearce of clathrin, the first protein found to act in membrane traffic, along with her mentoring and support of the pioneers (many of whom were other women) who revealed the workings of this key player in cellular function. 03419
Reposted by MRC-LMB Cell Biology DivisionMothers in Science @mothersinsci.bsky.social · 28/08/2026Join our team! 📣 If you are passionate about creating a more equitable system for mothers & caregivers in STEMM, can commit 2h per week & have experience in writing or content creation, we'd love to hear from you! Apply now👇https://tinyurl.com/yc3kx4m8 001
Reposted by MRC-LMB Cell Biology DivisionMark Peifer (He, him) @peiferlabunc.bsky.social · 26/08/2026Pro tip: Most of these @dshb-antibodies.bsky.social Abs are documented in dozens of publications and are also substantially cheaper. 15529
Reposted by MRC-LMB Cell Biology DivisionKurianlab @kurianlab.bsky.social · 26/08/2026dshb.biology.uiowa.edu We should support and make better use of hybridoma bank Maintained by a small team at the University of Iowa’s Developmental Studies Hybridoma Bankdshb.biology.uiowa.eduDevelopmental Studies Hybridoma Bank - DSHBHigh quality, low cost antibodies. 12315
Reposted by MRC-LMB Cell Biology DivisionMary Munson @marymunson4.bsky.social · 26/08/2026Structural biology postdoctoral position open in my lab--apply now! For more information about the lab, see www.umassmed.edu/munsonlab/. Interested candidates should apply through the University of Massachusetts Chan Medical School jobs portal (www.ummsjobs.com/job/11668/).umassmed.eduMunson Lab | Home | BMB | UMass Chan Medical SchoolThe Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me... 12744
Reposted by MRC-LMB Cell Biology DivisionAndré Nadler @nadlerlab.bsky.social · 21/08/2026Rocket science. The NMR part is a true stunner. Let me put it very kindly: We ain't there yet & burning through god knows how much compute time to achieve something that "the operating software of the spectrometer" does automatically & instantly... www.anthropic.com/research/Cla...anthropic.comHow Claude is accelerating protein design and analytical chemistryIn this post, we share two results that show how Claude can help life scientists increase the pace of their research. In the first, we tested Claude’s ability to design protein binders from scratch, a... 1102
Reposted by MRC-LMB Cell Biology DivisionFlyBase @flybase.bsky.social · 20/08/2026Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...nature.comTreat biological databases as infrastructure, not projectsLetter to the Editor 17645
Reposted by MRC-LMB Cell Biology DivisionThe Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · 18/08/2026An extra vid today 🙌 Lister Fellow @kellythd-nguyen.bsky.social shares her research on telomerase. Using cryo-electron microscopy, she's been able to see the structure of this enzyme and make sense of many disease mutations. 👀 www.youtube.com/watch?v=ciP2... 📖 www.eppendorf.com/gb-en/compan...youtube.comThe balance at the ends of our chromosomes - Kelly Nguyen on Telomerase, Aging and BalanceOne of the rarest molecules in the human body is the enzyme complex telomerase. Yet it can decide our fate, in terms of ageing, cancer and some inherited diseases. Kelly Nguyen studies how the… 062
Reposted by MRC-LMB Cell Biology DivisionCell Biology J-Club @cellclub.bsky.social · 18/08/2026Architecture and mechanism of the human p24 cargo receptor | PNAS www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 022
Reposted by MRC-LMB Cell Biology DivisionMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 18/08/2026Exciting plans for a new national hub at @scicambridge.bsky.social to advance novel alternative methodologies for disease models. @lancasterlab.bsky.social will co-lead neuroscience models, including brain organoids. Read more: www.bbc.co.uk/news/article... #LMBintheNews @cellbiol-mrclmb.bsky.socialbbc.co.ukPlans for £20m hub in Cambridge to develop new medicines using AIThe hub is funded by the Medical Research Council and based at Cambridge Biomedical Campus. 074
Reposted by MRC-LMB Cell Biology DivisionIn Preparation @inprep.bsky.social · 18/08/2026inpreparation.substack.comPI Who Took Credit For Paper Clarifies Fraud Was Student’s Independent WorkBOSTON, MA—In a statement released Monday following the retraction of a high-profile Nature paper, Whitehead Institute principal investigator Dr. 2167
Reposted by MRC-LMB Cell Biology DivisionJon Humphries @jdhl18.bsky.social · 16/08/2026And here's the direct link to the JCS at a glance archive: journals.biologists.com/jcs/search-r...journals.biologists.comValidate User 065
Reposted by MRC-LMB Cell Biology DivisionMill_lab @cilialab.bsky.social · 16/08/2026Join us for the 56th BSCB GenSoc UK Cilia & Centrosome Network e-symposium! 🧪Free & for all! /1 🗓️ AUGUST 25th 2026 ⌚ 15:00-17:30 BST | 16:00-18:30 CEST | 10:00-12:30 EDT ukcilianetwork.bsky.social gensocuk.bsky.social @bscb-official.bsky.social Register once: www.eventbrite.co.uk/e/bscb-genso...eventbrite.co.ukBSCB GenSoc UK Cilia and Centrosome Network e-Symposia SeriesBSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series 175
Reposted by MRC-LMB Cell Biology DivisionLori Passmore @lapassmore.bsky.social · 14/08/2026Ben Nicholson at the CRUK Cambridge Institute is recruiting a new postdoc to investigate piRNA biology. This is a collaborative project with my group at MRC Laboratory of Molecular Biology (LMB). Interested? Apply or get in touch to discuss! tinyurl.com/y25z8wkncam.ac.ukPostdoctoral Research Associate (piRNA Team) (Fixed Term)The Cancer Research UK Cambridge Institute is situated on the Biomedical Campus in Cambridge, UK. As part of the University of Cambridge, the institute's research ranges from basic biology through tra... 0127
Reposted by MRC-LMB Cell Biology DivisionCell Biology J-Club @cellclub.bsky.social · 11/08/2026www.biorxiv.org/content/10.6...biorxiv.orgCornichon receptors couple membrane adaptation to cargo selection during ER exportSelective export of membrane proteins from the endoplasmic reticulum (ER) is fundamental for eukaryotic cell biology, yet how trafficking receptors coordinate cargo recognition with membrane adaptatio... 032
Reposted by MRC-LMB Cell Biology DivisionHeran Darwin, PhD @heran.bsky.social · 10/08/2026BlueSky doesn't seem to spread the word around as effectively as that other app so I'm reposting this incredible opportunity again (and again!). Please repost and spread the word to strong candidates. Thank you! 0511
Reposted by MRC-LMB Cell Biology DivisionIn Preparation @inprep.bsky.social · 07/08/2026inpreparation.substack.comPharma Executives Confident China Cycle That Has Happened To Every Other Industry Will Not Happen To PharmaCAMBRIDGE, MA—Expressing calm assurance that the pattern of technology transfer, appropriation, and eventual displacement that has occurred in manufacturing, solar panels, semiconductors, telecommunications,... 0136
Reposted by MRC-LMB Cell Biology Divisiondshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 05/08/2026What antibody question keeps coming up in your lab? The DSHBlog shares practical guidance, research stories, and the knowledge behind widely used reagents—so what works at the bench is easier to find and share. dshb.biology.uiowa.edu/blogdshb.biology.uiowa.edublog 001
Reposted by MRC-LMB Cell Biology DivisionHeran Darwin, PhD @heran.bsky.social · 03/08/2026Please don't miss this opportunity to work with a brilliant, patient and rigorous scientist!! 043
Reposted by MRC-LMB Cell Biology DivisionLiz Miller @lizmillercu.bsky.social · 31/07/2026Job alert! I'm recruiting a new post-doc to work on mechanisms of co-translational quality control in the ER. Looking for expertise in ribosome biology and yeast genetics/cell biology. Please reach out to me with any questions. www.dundee.ac.uk/work-for-us/...dundee.ac.ukPostdoctoral Research Assistant - UOD2336Closing date: Thursday 27 August 2026, 23:59 01425
Reposted by MRC-LMB Cell Biology DivisionJournal of Cell Science @jcellsci.bsky.social · 29/07/2026Igor Yakunin, Sean Munro @cellbiol-mrclmb.bsky.social and colleagues find that the Golgi vesicle tether p115 can bind directly to the ER exit site organiser Sec16A. #OpenAccess #ReadandPublish journals.biologists.com/jcs/article/... 0126
Reposted by MRC-LMB Cell Biology DivisionJulian Sale @juliansalelab.bsky.social · 27/07/2026Growing up in the Northwest, Jodrell Bank helped inspire my interest in science. To hear of its funding being cut by @ukri.org is extremely sad, and an act of monumental vandalism that diminishes UK science in so many ways, including its ability to excite little kids... www.bbc.co.uk/news/article...bbc.co.ukJodrell Bank's Lovell telescope faces axe in science cuts, BBC understandsAstronomers warn it would tear the heart out of UK science, and leave a generation untrained. 094