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Andrew Boyce

@andrewboyce.bsky.social
408 followers 392 following 50 posts

🇨🇦 Assistant Professor @UNMHSC Neurosciences Exploring spreading depolarization during seizure & stroke using optogenetics, ephys, photometry, & microscopy. Enthusiastic but mediocre runner & climber. Thompson, Nägerl & Swayne lab alumnus. (he/him)

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Andrew Boyce @andrewboyce.bsky.social · 09/01/2026
Fun day building a ´basic’ fiber photometry setup for green fluorescent biosensors with rotating student Lauryn! (🥹 Please excuse the lack of mounted equipment happening, this was a rough-in). As you can see by the number of LED drivers, the end result of this build will be less ‘basic’.
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Ciaran Murphy-Royal @murphyroyallab.org · 05/01/2026
🚨 PI position in dept. of Neuroscience with lab located the @crchum.bsky.social Hiring at assistant/associate prof level in the fields of neural regeneration, stem cells and spinal-associated pathologies can-acn.org/professor-re...
can-acn.org
Professor-researcher (assistant or associate) in Neuroscience related to neural regeneration, stem cells and spinal-associated pathologies – Université de Montréal – Canadian Association for Neuroscie...
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Andrew Boyce @andrewboyce.bsky.social · 16/12/2025
Very much enjoyed my visit to Bonn & Michael Wenzel’s group for a chance to share some new data and discuss together future directions in hippocampal SD research. Excited to work together! (Also great to catch up over lunch with Martin Fuhrmann!)
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Andrew Boyce @andrewboyce.bsky.social · 13/12/2025
Dream come true last night - Rachelle surprised me on our flight over to ICSD with tickets for Radiohead in Berlin!
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Andrew Boyce @andrewboyce.bsky.social · 24/11/2025
Extremely New Mexico view from my front porch this morning:
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Andrew Boyce @andrewboyce.bsky.social · 21/11/2025
Excited to share the first publication out of my lab! www.jove.com/t/69418/simu... We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.
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Andrew Boyce @andrewboyce.bsky.social · 07/11/2025
So great to have you for a visit! Looking forward to staying in touch.
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FPbase @fpbase.org · 04/11/2025
The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/
fpbase.org
FPbase Fluorescence Spectra Viewer
An interactive fluorescence spectra viewer to evaluate the spectral properties of fluorescent proteins, organic dyes, filters, and detectors.
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Joachim Goedhart @joachimgoedhart.bsky.social · 26/10/2025
www.nature.com/articles/d41...
nature.com
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
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David @dav1dcg.bsky.social · 19/10/2025
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering. www.nature.com/articles/s41...
nature.com
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice - Nature Communications
The authors present the adaptive optics system MD-FSS, which allows high-resolution brain imaging in awake mice with rapid aberrations correction against motion. It reveals differences in brain functi...
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Wendy Xin @droligo.bsky.social · 10/10/2025
Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair! (see also - gorgeous astrocytes for fluorescence Friday) www.sciencedirect.com/science/arti...
Fluorescently labeled astrocytes at varying distances from cortical or white matter stroke infarct border
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Andrew Boyce @andrewboyce.bsky.social · 04/10/2025
Experienced Albuquerque’s balloon fiesta for the first time today! Very cool.
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Andrew Boyce @andrewboyce.bsky.social · 22/09/2025
Really fun weekend exploring Southern NM - stopped in at a roastery in Hatch (home of the chile) & camped near White Sands National Park - this state is so cool!
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Andrew Boyce @andrewboyce.bsky.social · 17/09/2025
Hippocampal SD on the cover of STM! 😍
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Andrew Boyce @andrewboyce.bsky.social · 04/09/2025
I’m in the market for a fanless solid state (DPSS) 561 nm laser & both companies I’ve purchased from in the past seem to have either vanished or aren’t replying to my inquiries & quote requests 👻 anyone have a good source?
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Craig Brown @craigedbrown.bsky.social · 27/05/2025
Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Retrograde and anterograde trans-synaptic viral tracing of neuronal connections reveals local and distant effects of ischemic stroke on dendritic spines - Myrthe Van Sprengel, Jenna Butterworth, Patri...
Focal stroke leads to complex neurological disturbances with variable recovery. One explanation for this variability is that stroke disrupts local and remote ne...
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Zach Rosenthal @zachrosenthal.bsky.social · 18/05/2025
Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below! doi.org/10.1038/s414...
doi.org
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature Communications
The underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon...
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Ben Kanter @beneuroscience.bsky.social · 26/04/2025
As I transition over to Bluesky I have to plug our new #book. If you haven't already, check out the 2nd edition of The #Hippocampus Book! academic.oup.com/book/59509?s...
academic.oup.com
The Hippocampus Book
Abstract. The Hippocampus Book investigates the structure, function and pathology of the hippocampus and related cortical areas. It highlights the importan
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Andrew Boyce @andrewboyce.bsky.social · 10/04/2025
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory! neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org
Postdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...
Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys!
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Louis-Eric Trudeau @louistrudeau.bsky.social · 24/04/2025
I have an opening in my lab for a postdoctoral fellow to work on projects that relate to the mechanisms of neurotransmitter release by dopamine neurons and/or on how inflammatory signals infuence the functionning of these neurons. Please share.
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piatkevich.bsky.social @piatkevich.bsky.social · 18/04/2025
mScarlet3-H (aka mYongHong), a highly stable monomeric red fluorescent protein, works well for long-term super-resolution imaging, rapid tissue clearing, and CLEM www.nature.com/articles/s41...
nature.com
A highly stable monomeric red fluorescent protein for advanced microscopy - Nature Methods
The red fluorescent protein mScarlet3-H is bright, photostable and very robust to high temperature, chaotropic conditions and oxidative environments. mScarlet3-H works well in correlative light and el...
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Canadian Association for Neuroscience @canacn.bsky.social · 15/04/2025
We are very proud to announce the winner of the 2025 CAN New Investigator Award: Dr. Mark Cembrowski, Associate Professor at the University of British Columbia - Read his profile here: can-acn.org/awards/new-i...
Mark Cembrowski
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Paul Frankland @franklandlab.bsky.social · 10/04/2025
Thrilled to share new work from the lab, led by Adam Ramsaran: authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com
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Andrew Boyce @andrewboyce.bsky.social · 10/04/2025
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory! neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org
Postdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...
Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys!
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Andrew Boyce @andrewboyce.bsky.social · 10/04/2025
Excited to share the culmination of my postdoctoral work in the Thompson Lab out today in Nature Communications! rdcu.be/ehfWU
rdcu.be
Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Nature Communications - Neural mechanisms underlying deep brain strokes are not fully understood. Here authors demonstrate that spreading depolarizations occur in the intact contralesional...
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CLaE @claeneuro.bsky.social · 23/03/2025
Science Hippocampal encoding of memories in human infants #neuroscience www.science.org/doi/10.1126/...
science.org
Hippocampal encoding of memories in human infants
Humans lack memories for specific events from the first few years of life. We investigated the mechanistic basis of this infantile amnesia by scanning the brains of awake infants with functional magne...
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Andrew Boyce @andrewboyce.bsky.social · 18/03/2025
Please share! 👀 Postdoc opportunity in my lab at the University of New Mexico. Spreading depolarization & memory interactions.
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Andrew Boyce @andrewboyce.bsky.social · 17/03/2025
Website for the Boyce Lab is live! I couldn't help it and included a bit of a New Mexico colour scheme. www.boyceneurolab.com
boyceneurolab.com
The Boyce Lab
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Igor Brodsky @brodskyigorlab.bsky.social · 13/03/2025
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
forbes.com
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
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Andrew Boyce @andrewboyce.bsky.social · 28/02/2025
Fun day combining work & a hike in San Lorenzo Canyon with colleagues Sam, David, & visiting speaker @olsenlab-vt.bsky.social
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Caroline Menard @caromenard666.bsky.social · 27/02/2025
So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳 Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI www.nature.com/articles/s41...
nature.com
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature Neuroscience
The mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri...
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Andrew Boyce @andrewboyce.bsky.social · 21/02/2025
It’s now the end of week 3 after opening my lab here at UNM.edu - It’s an understatement to say that it’s a weird time to be a Canadian starting a lab in the US. 🫠 Yet, I’ve felt so welcome and supported here. On top of that, a colleague just brought me this cool mug 😎 Psyched to get things going!
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Milene Vandal @milenevandal.bsky.social · 31/01/2025
I am pleased to share our work showing a new role for the Alzheimer’s disease risk factor CD2AP in brain endothelial cells now published in @cp-neuron.bsky.social. www.sciencedirect.com/science/arti...
sciencedirect.com
Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction
Polymorphisms in CD2-associated protein (CD2AP) predispose to Alzheimer’s disease (AD), but the underlying mechanisms remain unknown. Here, we show th…
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Caroline Menard @caromenard666.bsky.social · 09/01/2025
PhD student? Postdoc? Staff scientist? It's your chance to learn more about fancy 🧠 neuroscience 🧪 imaging techniques, microscopes 🔬 and hangout in Quebec City 🇨🇦 for 2 weeks in June 😎 (no snow I promise 🤞☃️😆) Please share, deadline is January 17 and link to apply is below
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Andrew Boyce @andrewboyce.bsky.social · 31/12/2024
A year ago today, Rachelle & I got married. It’s been a wild & fun year with so many changes. As scientists, particular during big transitions, we don’t make it easy on our partners. Rachelle is so supportive & game for (or creating her own) crazy ideas. So excited for our future together in ABQ!
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Jonas Wietek @jwietek.bsky.social · 29/12/2024
www.biorxiv.org/content/10.1... @piatkevich.bsky.social
biorxiv.org
Genetically Encoded Red Fluorescent Indicators for Imaging Intracellular and Extracellular Potassium Ions
Potassium ion (K+) dynamics are vital for various biological processes. However, the limited availability of detection tools for tracking intracellular and extracellular K+ has impeded a comprehensive...
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Marc Somssich @somssich.bsky.social · 20/05/2024
Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇
A profile picture of Douglas Prasher from Martin Chalfie's Nobel Lecture
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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 20/12/2024
What a year! #DLC3🔥 is up tested by many of you (👀 watch out for a paper in 2025), we hit 750K downloads, and have over 120 contributors to the code! @deeplabcut.bsky.social ❄️⛷just dropped: new human pose models & high perf. models!
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Andrew Boyce @andrewboyce.bsky.social · 24/12/2024
Recently submitted a revised version of our study on contralesional hippocampal spreading depolarizations during acute focal ischemic stroke & it’s now available on bioRxiv just in time for Christmas!
biorxiv.org
Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Ischemic stroke, brain tissue infarction following obstructed cerebral blood flow, leads to long-term neurological deficits and death. While neocortex is a commonly affected region with established pr...
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Andrew Boyce @andrewboyce.bsky.social · 22/12/2024
Yesterday - on my last run before the holidays - I passed my yearly distance goal. It’s been a fun running year. In July, I finished my first ultramarathon, but also realized the value of run commuting for clear thinking during a rather busy period of my work life. Can’t wait for more in New Mexico!
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Paul Frankland @franklandlab.bsky.social · 17/12/2024
Scientist position at The Hospital for Sick Children in Toronto. We are looking for neuroscientists with interests in the molecular and cellular bases of cognition. The position is open-rank, and the successful candidate will also be appointed at U Toronto. Deadline is Feb 15th. Come join us!
career.sickkids.ca
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adamezracohen.bsky.social @adamezracohen.bsky.social · 12/12/2024
If some calcium enters a dendrite, how far does it diffuse? Rebecca Frank Hayward (who is on the job market!) measured this. www.sciencedirect.com/science/arti... She combined a blue light-activated Ca++ channel with a red-fluorescent Ca++ sensor. The length constant is about 5 microns.
sciencedirect.com
All-optical mapping of Ca2+ transport and homeostasis in dendrites
Calcium mediates many important signals in dendrites. However, the basic transport properties of calcium in dendrites have been difficult to measure: …
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Paul Frankland @franklandlab.bsky.social · 11/12/2024
Coming soon: We have a Scientist position in the Neuroscience & Mental Health Program at SickKids. Should post details later this week. Stay tuned.
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Cedric Boeckx @cedricboeckx.bsky.social · 08/12/2024
Such a nice, comprehensive review by @marcvoo.bsky.social and @erin-schuman.bsky.social on the molecular diversity of synapses (h/t @djabaudon.bsky.social): www.nature.com/articles/s41...
nature.com
Understanding the molecular diversity of synapses - Nature Reviews Neuroscience
The set of proteins present at synapses determines their heterogeneous functions and properties. In this Review, van Oostrum and Schuman describe the molecular mechanisms that contribute to the d...
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Alice Ting @aliceyting.bsky.social · 04/12/2024
Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation..
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Andrew Boyce @andrewboyce.bsky.social · 04/12/2024
A “lab manual” is such a great idea. Looking forward to building my own!
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Andrew Boyce @andrewboyce.bsky.social · 03/12/2024
Just cracked the spine on At The Helm (thanks for the recommendation @ciaranmr.bsky.social !) - what other resources should I be checking out now that it’s T-2 months til I open my lab?
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Craig Brown @craigedbrown.bsky.social · 28/11/2024
Congrats to the team! Here we directly image and quantify cerebral #angiogenesis and pruning in vivo. Found interesting regional differences and dependence on #notch signalling. Where you look does matter! www.cell.com/cell-reports...
cell.com
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner
The angiogenic capacity of the mature healthy brain and its underlying mechanisms are unclear. Raudales et al. show that rates of cerebral angiogenesis follow regional gradients and are regulated by e...
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Jesper Sjöström @pjsjostrom.bsky.social · 22/11/2024
The call for participating in the Summer School Frontiers in Neurophotonics June 2nd to 13th, 2025 in Quebec City, Canada is now open! One of my trainees went last year and had a great experience, so I wanted to recommend it! neurophotonics.ca/frontiers-in...
neurophotonics.ca
Frontiers in Neurophotonics Summer School - Neurophotonics Centre
The 18th Edition of the Frontiers in Neurophotonics Summer School will take place, from June 2nd to 13th, 2025, at the CERVO Brain Research Center in Quebec City. 2024 Sponsors
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Joachim Goedhart @joachimgoedhart.bsky.social · 21/11/2024
Nice work from Yasushi Okada and colleagues on the development of fluorescence lifetime biosensors for ATP, cAMP, citrate, and glucose using mTurquoise2 www.cell.com/cell-reports...
Construction, characterization, and validation of qmTQ2-ATP biosensor
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