Andrew Boyce @andrewboyce.bsky.social · 09/01/2026Fun day building a ´basic’ fiber photometry setup for green fluorescent biosensors with rotating student Lauryn! (🥹 Please excuse the lack of mounted equipment happening, this was a rough-in). As you can see by the number of LED drivers, the end result of this build will be less ‘basic’. 000
Reposted by Andrew BoyceCiaran Murphy-Royal @murphyroyallab.org · 05/01/2026🚨 PI position in dept. of Neuroscience with lab located the @crchum.bsky.social Hiring at assistant/associate prof level in the fields of neural regeneration, stem cells and spinal-associated pathologies can-acn.org/professor-re...can-acn.orgProfessor-researcher (assistant or associate) in Neuroscience related to neural regeneration, stem cells and spinal-associated pathologies – Université de Montréal – Canadian Association for Neuroscie... 11013
Andrew Boyce @andrewboyce.bsky.social · 16/12/2025Very much enjoyed my visit to Bonn & Michael Wenzel’s group for a chance to share some new data and discuss together future directions in hippocampal SD research. Excited to work together! (Also great to catch up over lunch with Martin Fuhrmann!) 000
Andrew Boyce @andrewboyce.bsky.social · 13/12/2025Dream come true last night - Rachelle surprised me on our flight over to ICSD with tickets for Radiohead in Berlin! 060
Andrew Boyce @andrewboyce.bsky.social · 24/11/2025Extremely New Mexico view from my front porch this morning: 000
Andrew Boyce @andrewboyce.bsky.social · 21/11/2025Excited to share the first publication out of my lab! www.jove.com/t/69418/simu... We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core. 3183
Andrew Boyce @andrewboyce.bsky.social · 07/11/2025So great to have you for a visit! Looking forward to staying in touch. 010
Reposted by Andrew BoyceFPbase @fpbase.org · 04/11/2025The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/fpbase.orgFPbase Fluorescence Spectra ViewerAn interactive fluorescence spectra viewer to evaluate the spectral properties of fluorescent proteins, organic dyes, filters, and detectors. 511336
Reposted by Andrew BoyceJoachim Goedhart @joachimgoedhart.bsky.social · 26/10/2025www.nature.com/articles/d41...nature.comWhat makes PhD students happy? Good supervisionSupervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research. 13113
Reposted by Andrew BoyceDavid @dav1dcg.bsky.social · 19/10/2025Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering. www.nature.com/articles/s41...nature.comRapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice - Nature CommunicationsThe authors present the adaptive optics system MD-FSS, which allows high-resolution brain imaging in awake mice with rapid aberrations correction against motion. It reveals differences in brain functi... 064
Reposted by Andrew BoyceWendy Xin @droligo.bsky.social · 10/10/2025Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair! (see also - gorgeous astrocytes for fluorescence Friday) www.sciencedirect.com/science/arti... 1308
Andrew Boyce @andrewboyce.bsky.social · 04/10/2025Experienced Albuquerque’s balloon fiesta for the first time today! Very cool. 2131
Andrew Boyce @andrewboyce.bsky.social · 22/09/2025Really fun weekend exploring Southern NM - stopped in at a roastery in Hatch (home of the chile) & camped near White Sands National Park - this state is so cool! 000
Andrew Boyce @andrewboyce.bsky.social · 04/09/2025I’m in the market for a fanless solid state (DPSS) 561 nm laser & both companies I’ve purchased from in the past seem to have either vanished or aren’t replying to my inquiries & quote requests 👻 anyone have a good source? 000
Reposted by Andrew BoyceCraig Brown @craigedbrown.bsky.social · 27/05/2025Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...journals.sagepub.comRetrograde and anterograde trans-synaptic viral tracing of neuronal connections reveals local and distant effects of ischemic stroke on dendritic spines - Myrthe Van Sprengel, Jenna Butterworth, Patri...Focal stroke leads to complex neurological disturbances with variable recovery. One explanation for this variability is that stroke disrupts local and remote ne... 1105
Reposted by Andrew BoyceZach Rosenthal @zachrosenthal.bsky.social · 18/05/2025Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below! doi.org/10.1038/s414...doi.orgElectroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature CommunicationsThe underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon... 32911
Reposted by Andrew BoyceBen Kanter @beneuroscience.bsky.social · 26/04/2025As I transition over to Bluesky I have to plug our new #book. If you haven't already, check out the 2nd edition of The #Hippocampus Book! academic.oup.com/book/59509?s...academic.oup.comThe Hippocampus BookAbstract. The Hippocampus Book investigates the structure, function and pathology of the hippocampus and related cortical areas. It highlights the importan 1269
Reposted by Andrew BoyceAndrew Boyce @andrewboyce.bsky.social · 10/04/2025The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory! neurojobs.sfn.org/job/38785/po...neurojobs.sfn.orgPostdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys! 022
Reposted by Andrew BoyceLouis-Eric Trudeau @louistrudeau.bsky.social · 24/04/2025I have an opening in my lab for a postdoctoral fellow to work on projects that relate to the mechanisms of neurotransmitter release by dopamine neurons and/or on how inflammatory signals infuence the functionning of these neurons. Please share. 11313
Reposted by Andrew Boycepiatkevich.bsky.social @piatkevich.bsky.social · 18/04/2025mScarlet3-H (aka mYongHong), a highly stable monomeric red fluorescent protein, works well for long-term super-resolution imaging, rapid tissue clearing, and CLEM www.nature.com/articles/s41...nature.comA highly stable monomeric red fluorescent protein for advanced microscopy - Nature MethodsThe red fluorescent protein mScarlet3-H is bright, photostable and very robust to high temperature, chaotropic conditions and oxidative environments. mScarlet3-H works well in correlative light and el... 093
Reposted by Andrew BoyceCanadian Association for Neuroscience @canacn.bsky.social · 15/04/2025We are very proud to announce the winner of the 2025 CAN New Investigator Award: Dr. Mark Cembrowski, Associate Professor at the University of British Columbia - Read his profile here: can-acn.org/awards/new-i... 11558
Reposted by Andrew BoycePaul Frankland @franklandlab.bsky.social · 10/04/2025Thrilled to share new work from the lab, led by Adam Ramsaran: authors.elsevier.com/a/1kva73QW8S...authors.elsevier.com 2389
Andrew Boyce @andrewboyce.bsky.social · 10/04/2025The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory! neurojobs.sfn.org/job/38785/po...neurojobs.sfn.orgPostdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys! 022
Andrew Boyce @andrewboyce.bsky.social · 10/04/2025Excited to share the culmination of my postdoctoral work in the Thompson Lab out today in Nature Communications! rdcu.be/ehfWUrdcu.beContralesional hippocampal spreading depolarization promotes functional recovery after strokeNature Communications - Neural mechanisms underlying deep brain strokes are not fully understood. Here authors demonstrate that spreading depolarizations occur in the intact contralesional... 2254
Reposted by Andrew BoyceCLaE @claeneuro.bsky.social · 23/03/2025Science Hippocampal encoding of memories in human infants #neuroscience www.science.org/doi/10.1126/...science.orgHippocampal encoding of memories in human infantsHumans lack memories for specific events from the first few years of life. We investigated the mechanistic basis of this infantile amnesia by scanning the brains of awake infants with functional magne... 0113
Andrew Boyce @andrewboyce.bsky.social · 18/03/2025Please share! 👀 Postdoc opportunity in my lab at the University of New Mexico. Spreading depolarization & memory interactions. 021
Andrew Boyce @andrewboyce.bsky.social · 17/03/2025Website for the Boyce Lab is live! I couldn't help it and included a bit of a New Mexico colour scheme. www.boyceneurolab.comboyceneurolab.comThe Boyce Lab 020
Reposted by Andrew BoyceIgor Brodsky @brodskyigorlab.bsky.social · 13/03/2025In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...forbes.comNIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New ReportNational Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research. 4193106
Andrew Boyce @andrewboyce.bsky.social · 28/02/2025Fun day combining work & a hike in San Lorenzo Canyon with colleagues Sam, David, & visiting speaker @olsenlab-vt.bsky.social 010
Reposted by Andrew BoyceCaroline Menard @caromenard666.bsky.social · 27/02/2025So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳 Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI www.nature.com/articles/s41...nature.comAstrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature NeuroscienceThe mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri... 2011535
Andrew Boyce @andrewboyce.bsky.social · 21/02/2025It’s now the end of week 3 after opening my lab here at UNM.edu - It’s an understatement to say that it’s a weird time to be a Canadian starting a lab in the US. 🫠 Yet, I’ve felt so welcome and supported here. On top of that, a colleague just brought me this cool mug 😎 Psyched to get things going! 050
Reposted by Andrew BoyceMilene Vandal @milenevandal.bsky.social · 31/01/2025I am pleased to share our work showing a new role for the Alzheimer’s disease risk factor CD2AP in brain endothelial cells now published in @cp-neuron.bsky.social. www.sciencedirect.com/science/arti...sciencedirect.comLoss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunctionPolymorphisms in CD2-associated protein (CD2AP) predispose to Alzheimer’s disease (AD), but the underlying mechanisms remain unknown. Here, we show th… 9195
Reposted by Andrew BoyceCaroline Menard @caromenard666.bsky.social · 09/01/2025PhD student? Postdoc? Staff scientist? It's your chance to learn more about fancy 🧠 neuroscience 🧪 imaging techniques, microscopes 🔬 and hangout in Quebec City 🇨🇦 for 2 weeks in June 😎 (no snow I promise 🤞☃️😆) Please share, deadline is January 17 and link to apply is below 063
Andrew Boyce @andrewboyce.bsky.social · 31/12/2024A year ago today, Rachelle & I got married. It’s been a wild & fun year with so many changes. As scientists, particular during big transitions, we don’t make it easy on our partners. Rachelle is so supportive & game for (or creating her own) crazy ideas. So excited for our future together in ABQ! 020
Reposted by Andrew BoyceJonas Wietek @jwietek.bsky.social · 29/12/2024www.biorxiv.org/content/10.1... @piatkevich.bsky.socialbiorxiv.orgGenetically Encoded Red Fluorescent Indicators for Imaging Intracellular and Extracellular Potassium IonsPotassium ion (K+) dynamics are vital for various biological processes. However, the limited availability of detection tools for tracking intracellular and extracellular K+ has impeded a comprehensive... 0144
Reposted by Andrew BoyceMarc Somssich @somssich.bsky.social · 20/05/2024Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇 3288150
Reposted by Andrew BoyceMackenzie Weygandt Mathis @trackingactions.bsky.social · 20/12/2024What a year! #DLC3🔥 is up tested by many of you (👀 watch out for a paper in 2025), we hit 750K downloads, and have over 120 contributors to the code! @deeplabcut.bsky.social ❄️⛷just dropped: new human pose models & high perf. models! 4509
Andrew Boyce @andrewboyce.bsky.social · 24/12/2024Recently submitted a revised version of our study on contralesional hippocampal spreading depolarizations during acute focal ischemic stroke & it’s now available on bioRxiv just in time for Christmas!biorxiv.orgContralesional hippocampal spreading depolarization promotes functional recovery after strokeIschemic stroke, brain tissue infarction following obstructed cerebral blood flow, leads to long-term neurological deficits and death. While neocortex is a commonly affected region with established pr... 020
Andrew Boyce @andrewboyce.bsky.social · 22/12/2024Yesterday - on my last run before the holidays - I passed my yearly distance goal. It’s been a fun running year. In July, I finished my first ultramarathon, but also realized the value of run commuting for clear thinking during a rather busy period of my work life. Can’t wait for more in New Mexico! 080
Reposted by Andrew BoycePaul Frankland @franklandlab.bsky.social · 17/12/2024Scientist position at The Hospital for Sick Children in Toronto. We are looking for neuroscientists with interests in the molecular and cellular bases of cognition. The position is open-rank, and the successful candidate will also be appointed at U Toronto. Deadline is Feb 15th. Come join us!career.sickkids.ca 38063
Reposted by Andrew Boyceadamezracohen.bsky.social @adamezracohen.bsky.social · 12/12/2024If some calcium enters a dendrite, how far does it diffuse? Rebecca Frank Hayward (who is on the job market!) measured this. www.sciencedirect.com/science/arti... She combined a blue light-activated Ca++ channel with a red-fluorescent Ca++ sensor. The length constant is about 5 microns.sciencedirect.comAll-optical mapping of Ca2+ transport and homeostasis in dendritesCalcium mediates many important signals in dendrites. However, the basic transport properties of calcium in dendrites have been difficult to measure: … 2144
Reposted by Andrew BoycePaul Frankland @franklandlab.bsky.social · 11/12/2024Coming soon: We have a Scientist position in the Neuroscience & Mental Health Program at SickKids. Should post details later this week. Stay tuned. 04823
Reposted by Andrew BoyceCedric Boeckx @cedricboeckx.bsky.social · 08/12/2024Such a nice, comprehensive review by @marcvoo.bsky.social and @erin-schuman.bsky.social on the molecular diversity of synapses (h/t @djabaudon.bsky.social): www.nature.com/articles/s41...nature.comUnderstanding the molecular diversity of synapses - Nature Reviews NeuroscienceThe set of proteins present at synapses determines their heterogeneous functions and properties. In this Review, van Oostrum and Schuman describe the molecular mechanisms that contribute to the d... 08123
Reposted by Andrew BoyceAlice Ting @aliceyting.bsky.social · 04/12/2024Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation.. 33434138
Andrew Boyce @andrewboyce.bsky.social · 04/12/2024A “lab manual” is such a great idea. Looking forward to building my own! 020
Andrew Boyce @andrewboyce.bsky.social · 03/12/2024Just cracked the spine on At The Helm (thanks for the recommendation @ciaranmr.bsky.social !) - what other resources should I be checking out now that it’s T-2 months til I open my lab? 242
Reposted by Andrew BoyceCraig Brown @craigedbrown.bsky.social · 28/11/2024Congrats to the team! Here we directly image and quantify cerebral #angiogenesis and pruning in vivo. Found interesting regional differences and dependence on #notch signalling. Where you look does matter! www.cell.com/cell-reports...cell.comAngiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent mannerThe angiogenic capacity of the mature healthy brain and its underlying mechanisms are unclear. Raudales et al. show that rates of cerebral angiogenesis follow regional gradients and are regulated by e... 2379
Reposted by Andrew BoyceJesper Sjöström @pjsjostrom.bsky.social · 22/11/2024The call for participating in the Summer School Frontiers in Neurophotonics June 2nd to 13th, 2025 in Quebec City, Canada is now open! One of my trainees went last year and had a great experience, so I wanted to recommend it! neurophotonics.ca/frontiers-in...neurophotonics.caFrontiers in Neurophotonics Summer School - Neurophotonics CentreThe 18th Edition of the Frontiers in Neurophotonics Summer School will take place, from June 2nd to 13th, 2025, at the CERVO Brain Research Center in Quebec City. 2024 Sponsors 044
Reposted by Andrew BoyceJoachim Goedhart @joachimgoedhart.bsky.social · 21/11/2024Nice work from Yasushi Okada and colleagues on the development of fluorescence lifetime biosensors for ATP, cAMP, citrate, and glucose using mTurquoise2 www.cell.com/cell-reports... 36116