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The plasticity of synaptic connections is critical to the functioning of local circuits as it is thought to underlie information processing and storage in th...

Learning and memory were long thought to be the domains of neurons and neural networks, but recent work across brain systems has established that astrocytes pla...

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Long known for different circuit roles, parvalbumin and somatostatin interneurons are shown by Morabito et al.,1 in this issue of Neuron, to differ in…

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Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

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The plasticity of synaptic connections is critical to the functioning of local circuits as it is thought to underlie information processing and storage in th...

Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...

In the textbook view, NMDA receptors (NMDARs) act as coincidence detectors in Hebbian plasticity by fluxing Ca2+ when simultaneously depolarized and glutamate bound. Hebbian coincidence detection requ...

Platform fosters collegial interactions among scientists, but potentially limits interactions beyond the academic community

The plasticity of synaptic connections is critical to the functioning of local circuits as it is thought to underlie information processing and storage in th...

Transient exposure to ketamine can trigger lasting changes in behavior and mood. We found that brief ketamine exposure causes long-term suppression of…

Synapse-specific connectivity and dynamics determine microcircuit function but are challenging to explore with classic paired recordings due to their low throughput. We therefore implemented optomapping, a ∼100-fold faster two-photon optogenetic method. In mouse primary visual cortex (V1), we optomapped 30,454 candidate inputs to reveal 1,790 excitatory inputs to pyramidal, basket, and Martinotti cells. Across these cell types, log-normal distribution of synaptic efficacies emerged as a principle.

The website of the International Astrocyte School :: 13th Edition :: IAS 2024

The 18th Edition of the Frontiers in Neurophotonics Summer School will take place, from June 2nd to 13th, 2025, at the CERVO Brain Research Center in Quebec City. 2024 Sponsors

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