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Igor Brodsky

@brodskyigorlab.bsky.social
4.6K followers 1.3K following 459 posts

Innate immunity/host-pathogen interactions. Husband, father, former Soviet immigrant. Opinions my own.

PostsRepliesMedia
Reposted by Igor Brodsky
Jenna Norton @jenna-m-norton.bsky.social · 16h
Disruption of global research at NIH is endangering people in the United States and around the world. 27unihted.substack.com/p/disruption... Foreign collaborations have been interrupted and discouraged and foreign scientists in the United States are working in an increasingly hostile environment.
27unihted.substack.com
Disruption of global research is endangering people in the United States and around the world
Concern 8 of the Bethesda Declaration: One Year Later
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Frustrated in Utah @marshallshuman.bsky.social · 20h
youtube.com/shorts/kseTb...
youtube.com
Robert De Niro: “I Want My Country Back” 😳 #RobertDeNiro #Trump #Shorts
YouTube video by Lamont Tyson
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Catherine Rampell @crampell.bsky.social · 20h
Pennsylvania reports 5th measles-associated death as outbreak continues. Cases in the state, home to the country’s largest ongoing measles outbreak, have climbed to 943 across 39 counties. www.washingtonpost.com/health/2026/...
washingtonpost.com
Pennsylvania reports 5th measles-associated death as outbreak continues
Cases in the state, home to the country’s largest ongoing measles outbreak, have climbed to 943 across 39 counties.
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Jeremy Berg @jeremymberg.bsky.social · 30/09/2026
My quote of the day There may be times when we are powerless to prevent injustice, but there must never be a time when we fail to protest. Elie Wiesel
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The Canadian Border 🇨🇦 @canadianborder.bsky.social · 29/09/2026
Canadian automakers have developed an EV car that can travel 500+ km on a single charge, shows snow covered lane lines on your windshield on snowy highways, and heatmaps animals on the side of the road so you have a warning about deer and moose at night. This is for us. BRING IT TO MARKET!! 😍❤️🍁
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Jenna Norton @jenna-m-norton.bsky.social · 29/09/2026
A great overview of how the Trump admin cultivated fear inside NIH to force compliance, even with harmful, unethical & unlawful orders. Also covers origins of the Bethesda Declaration community. From my friend & co-organizer Dr. Wen-Ying Sylvia Chou. www.psychologicalscience.org/publications...
psychologicalscience.org
NIH Employees Lived in A Culture of Fear, So They Started Keeping Receipts
Sylvia Chou, former NIH program director, says “nobody’s OK” after massive disruptions to funding policies and infrastructure.
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Jenna Norton @jenna-m-norton.bsky.social · 29/09/2026
Please read this letter with important considerations for training the next generation of clinical trialists. Its powerful that so many organizations came together. Thanks to everyone involved. Consider commenting on the NIH RFI by the 9/30 deadline: grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-095: REQUEST FOR INFORMATION (RFI): INPUT ON POTENTIAL NIH FUNDING APPROACHES TO SUPPORT THE DEVELOPMENT OF FUTURE CLINICAL TRIAL INVESTIGATORS
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: REQUEST FOR INFORMATION (RFI): INPUT ON POTENTIAL NIH FUNDING APPROACHES TO SUPPORT THE DEVELOPMENT OF FUTURE CLINICAL ...
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God @thegodshow.com · 27/09/2026
Thou shalt not use tax dollars to pay for fascist commercials.
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Catherine Rampell @crampell.bsky.social · 27/09/2026
A federal judge has declared that the Trump administration unlawfully terminated $7 billion in grant funding for clean energy programs in disadvantaged communities. insideclimatenews.org/news/2109202...
insideclimatenews.org
Federal Judge Rules Against Trump Administration Over Canceled Clean Energy Grants - Inside Climate News
The Solar for All program was intended to provide dozens of grants for clean energy programs in underserved communities. The Trump-appointed judge said the program’s termination was unlawful.
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Igor Brodsky @brodskyigorlab.bsky.social · 27/09/2026
The power of funding fundamental discovery in driving unexpected benefits for humankind are unmatched. We should be funding more basic research not less
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UCSF @ucsanfrancisco.bsky.social · 26/09/2026
UCSF’s Kevan Shokat, PhD, just won the $1M Stephenson Global Prize for research in pancreatic cancer. He cracked KRAS, a cancer driver long considered “undruggable.” Drugs built on his work now treat lung and pancreatic cancer. ow.ly/UYuY50ZRSXg
Middle-aged man in a blue lab coat smiling while seated in a scientific laboratory setting.Hand wearing black glove holding five small glass vials with various colored liquids, including pink and orange hues.
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eLife @elife.bsky.social · 26/09/2026
Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to <i>Plasmodium</i> infection
buff.ly
Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection
TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host...
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Mark Histed @markhisted.org · 23/09/2026
Can confirm (see 🧵 ). But let me share some optimism. A NIH colleague said today that against all odds, NIH has been…winning. “We made this EO a necessity. We fought hard. We threw sand in all the gears. All the lowdown ways of blocking grants failed to produce the results Vought et al wanted.”
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Joshua Weitz @joshuasweitz.bsky.social · 23/09/2026
New long-form post on the proposed Executive Order that would give OMB Director Russell Vought veto power over NIH funding decisions.
joshuasweitz.substack.com
An Emperor of All Malice: Contesting Efforts to Control NIH Funding
Unilateral efforts by the White House to politicize funding decisions jeopardize discovery, health, and the economy… and demand a timely, effective response.
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Alt-NIHscience4ALL @alt-nihscience4all.altgov.info · 21/09/2026
We need help standing up TOGETHER against this Vought takeover. This means academic and biotech/pharma scientists AND institutions. We CANNOT do this alone. There is already too much political interference in science from this regime.
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themedici.bsky.social @themedici.bsky.social · 21/09/2026
Rep. Sydney Kamlager-Dove has introduced articles of impeachment against Russell Vought. Contact your representative and tell them to co-sponsor! kamlager-dove.house.gov/media/press-...
kamlager-dove.house.gov
Kamlager-Dove Introduces Articles of Impeachment Against OMB Director Russell Vought
WASHINGTON, D.C. — Today, Congresswoman Sydney Kamlager-Dove (CA-37)introduced articles of impeachment against Office of Management and Budget (OMB)Director Russell Vought after the administration
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Blasé Boylan @blazesboylan.bsky.social · 20/09/2026
Never a bad time to mention that Vought cancelled research on the disease his daughter suffers from. This is who they are. www.motherjones.com/politics/202...
motherjones.com
Project 2025 is gutting medical funding that helped Russell Vought's own kid
Its architect's daughter has cystic fibrosis—and benefits from a "miracle drug" backed by an agency he's attacking.
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Catherine Rampell @crampell.bsky.social · 20/09/2026
Not an exaggeration to say when authoritarian thugs distort scientific research toward their own petty or prejudiced tastes, economies suffer, national security is compromised, people die. Exact proportion of each of those consequences varies from one authoritarian state to another, but all happen
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Catherine Rampell @crampell.bsky.social · 20/09/2026
It really is striking how many authoritarian states have ended up in this exact same place, where the leader seizes control of scientific inquiry. Lysenkoism in the Soviet Union, Aryan Physics in the Third Reich, Great Leap Forward (also related to Lysenko) in China.
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Shooti @bambooshooti.bsky.social · 21/09/2026
#ResistanceRoots Dorothy Vaughan was born on this day in 1910 in Kansas City, Mo. She was a mathematician, human computer and computer programmer who became the first African American supervisor at NASA. Throughout her career, she fought for equal pay and advancements and promotions for women. /1
Dorothy Vaughan in 1971, the year she retired from NASA. Vaughan was a visionary pioneer for women in STEM and a foundational architect of the U.S. space program. She broke through the dual barriers of Jim Crow segregation and gender discrimination to alter the course of aerospace history. Her calculations and FORTRAN programming laid the groundwork for America’s early aerospace achievements. By becoming NACA’s first African American supervisor in 1949, Vaughan cracked open doors that had been firmly shut to women of color. She spent her tenure as Section Head fighting for equal pay, promotions and engineering assignments for both Black and white women across the agency. When electronic computers arrived, she taught herself FORTRAN and trained her staff, saving dozens of Black women from layoffs and transitioning them into high-tech careers. Vaughan stands today as a symbol of resilience, intellectual brilliance and the indispensable power of community.
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Igor Brodsky @brodskyigorlab.bsky.social · 20/09/2026
By hook or by crook Russell Vought is determined to take control of the NIH budget. This is truly Lysenkoism in our time. White House Moves to Take Control of N.I.H. Grants www.nytimes.com/2026/09/20/s...
nytimes.com
White House Moves to Take Control of N.I.H. Grants
Federal officials are drafting an executive order that would place grants under review by an outside panel, the latest effort to redirect billions of dollars in research spending.
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the corghoul from cowboy beBOO! 👻 @realqrampage.fightins.online · 20/09/2026
Philly friends - sign this petition to save the Academy of Natural Sciences!
actionnetwork.org
Petition to Keep the Academy of Natural Sciences Open to the Public
The scientific community in Philadelphia and concerned neighbors are calling on Drexel University to keep the Academy of Natural Sciences of Philadelphia’s public-facing museum open beyond their impos...
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the corghoul from cowboy beBOO! 👻 @realqrampage.fightins.online · 20/09/2026
there’s also more you can do to save the Academy! you can write to your reps, put the pressure on Drexel’s president, and volunteer to educate others in Philly
save-the-academy.org
Save the Academy of Natural Sciences
Don't mourn — organize. The museum's last public day is Sunday, Sept 27. Ten things you can do today.
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Igor Brodsky @brodskyigorlab.bsky.social · 19/09/2026
www.cnn.com/2026/09/18/p... AI wouldn’t even have to actively do anything to start a war that could destroy humanity. It can just feed the wrong information to the wrong people and let things play out. We are way way past the time for guardrails.
cnn.com
Exclusive: US military had close call after using AI for false intelligence report, sources say | CNN Politics
The episode shows the risks of using this new, relatively poorly understood technology in the middle of the Iran war
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Ed Yong is offline @edyong209.bsky.social · 17/09/2026
Briefly popping my head back in to unveil the cover of my upcoming book, LIFE BEYOND MEASURE: Nature's Hidden Wonders at Every Scale. It’ll be out on April 6 in the U.S. and April 29 in the U.K. and you can pre-order it right now! www.penguinrandomhouse.com/books/757705... 1/
A book cover featuring a beautiful closely cropped portrait of an Anna's hummingbird. The cover says LIFE BEYOND MEASURE: Nature's Hidden Wonders at Every Scale, by Ed Yong. The image also says US: 4/06/27 and UK: 4/29/27
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Igor Brodsky @brodskyigorlab.bsky.social · 16/09/2026
The extent to which this administration’s policies are negatively impacting America’s present and future compettitveness in the world is totally mind blowing. If you were running a race this is the equivalent of breaking your own ankles and also putting weights on your back.
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Jennifer N. Victor @jenvictor.bsky.social · 16/09/2026
Banger of a piece from @donmoyn.bsky.social on US-China, science, and higher ed. Trump isn’t just killing US dominance in science & technology, he’s handing it to China. donmoynihan.substack.com/p/china-than...
donmoynihan.substack.com
China: “Thank Trump”
The big winner of Trump’s assault on higher ed is America’s chief geopolitical rival
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Bernard Kim @bernardkim.bsky.social · 15/09/2026
Princeton EEB is running a very broad faculty search at the Assistant Professor level. Please consider applying to join us! This is a wonderful, collaborative, cohesive department with diverse interests and amazing colleagues. apply.interfolio.com/193474
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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The Last Mile with USAID @thelastmilewithusaid.substack.com · 15/09/2026
Well written.
pennlive.com
What America lost when it shut down foreign aid | Opinion
A former USAID mission director reflects on decades of soft power diplomacy dismantled in months, and the human cost now surfacing worldwide.
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Gerry Carter @gerrycarter.bsky.social · 15/09/2026
Please help us spread the word: Princeton University’s Dept of Ecology and Evolutionary Biology is hiring an Assistant Professor! I ❤️ this collegial and collaborative department full of inspiring people: eeb.princeton.edu/people Apply here: apply.interfolio.com/193474
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Kumaran Ramamurthi @ramamurthilab.bsky.social · 15/09/2026
How do proteins localize in bacteria? Usually by binding to a prelocalized protein-but how does that protein localize? @vanipande.bsky.social found a #Bacillus subtilis protein that localizes via a lipid cue,undecaprenyl phosphate,that guides it to sites of PG synthesis www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Igor Brodsky @brodskyigorlab.bsky.social · 13/09/2026
“We are witnessing a general threat to intellectual work, with misalignment between the outcome of the use of AI & its initial purpose….years of training have traditionally served not only to produce a final answer…but also to develop understanding and the ability to formulate new questions & ideas”
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Terence Tao @teorth.bsky.social · 11/09/2026
A group of 25 Fields Medalists, including myself, have made a joint declaration on Math and AI: mathandai.org . We welcome additional signatories. See also this article in the Economist announcing the declaration: www.economist.com/science-and-...
mathandai.org
Declaration — Math and AI
Read the declaration and add your name.
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Greg Folkers @gregfolkers.bsky.social · 05/09/2026
ASM: Congress Must Reject Siphoning of NIH Funds to DoW bit.ly/4xKYUfo
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Gregg Gonsalves @gregggonsalves.bsky.social · 05/09/2026
Just remember, there were a handful of useful idiots in academia and elsewhere that championed Jay Bhattacharya for NIH director.
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Rep. Dr. Jasmine Clark @jasmineclarkforga.bsky.social · 30/08/2026
When babies in a daycare come in contact with measles, they are particularly vulnerable because children cannot be fully vaccinated until age 4 or 5. This is why RFK, Jr.’s anti-vax rhetoric is so dangerous! This is why we need science voices in Congress.
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Tasha @toshyou.bsky.social · 30/08/2026
NO media 1000s are marching in DC to defend voting rights; 90 orgs signed on, Reuters sent photographers, but local media Bernie Sanders, AOC and Martin Luther King III attended Wa Post buried it A Black-led march is visible in DC only after somebody else reports it Repost the march they buried
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Igor Brodsky @brodskyigorlab.bsky.social · 28/08/2026
The myth of the lone genius is just that. A myth. Asking for help and collaborating are key traits of highly successful people: www.nytimes.com/2026/08/28/o...
nytimes.com
Opinion | I Study Successful People. They Have One Habit in Common. (Gift Article)
Being a successful self-starter doesn’t mean pulling yourself up by your bootstraps.
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Hiten Madhani @hitenmadhani.bsky.social · 27/08/2026
Most basic science departments at UCSF are having faculty searches this year. Biochemistry & Biophysics, Microbiology & Immunology, Cellular and Molecular Pharmacology, Physiology and more. We're looking for new and exciting science and nice people. You'll find them all at aprecruit.ucsf.edu
aprecruit.ucsf.edu
Welcome - AP Recruit
University of California, San Francisco Online Faculty Recruitment
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Jenna Norton @jenna-m-norton.bsky.social · 01/07/2026
This is an excellent essay. “Gold standard science” is a label designed to undermine science, by withholding the label from any science deemed inconvenient to the profit or power of monied interests.
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One Action a Day … @oneactionaday.bsky.social · 01/07/2026
TODAY’s ACTION ITEM: Please click on the link below and send an email or make a call to SAVE SCIENCE from these morons. And grab a friend and get them to do it too! Thanks 🔬
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Julie Pfeiffer @jkpfeiff.bsky.social · 26/06/2026
Faculty search announcement 2026: Tenure-Track Assistant Professor in Microbiology at UT Southwestern in Dallas. We seek candidates working in microbial pathogenesis (broadly defined). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Department members sit at a very long table in the hallway eating a pre-Thanksgiving potluck feast.
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Rep. Jamie Raskin @raskin.house.gov · 25/06/2026
Public health research at world-class institutions like the NIH is an important public good. Rep. Suzan DelBene, Rep. Lori Trahan and I are leading 122 of our colleagues to oppose the Trump Administration’s efforts to give partisan political appointees final say over health research grants.
thebanner.com
Raskin moves to stop ‘disastrous’ threat against medical research
Rep. Jamie Raskin seeks to stop the Trump administration from putting political appointees in charge of federal health grants.
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Mark Histed @markhisted.org · 26/06/2026
Gregg gets it correct here. “New OMB grant rule” sounds nerdy. But this is a huge and insane plan. This is the Trump admin writing down their goal of fundamentally changing the relationship between government and society. Funding for everything will be taken over. 1/
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The New York Times @nytimes.com · 21/06/2026
In Opinion The system that turned Gila monster venom into GLP-1 drugs is being dismantled through research budget cuts, Jeff Coller writes in a guest essay. “Less support for scientists means strange questions no one will get to chase. Exploring those questions is how medicine advances.”
nyti.ms
Opinion | We Need to Keep Funding Weird Science
Science turned a serendipitous finding about lizard venom into one of the most important drugs of the century, but that type of research is getting harder to do.
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Ardem Patapoutian @ardemp.bskyverified.social · 24/06/2026
Please consider doing this!
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Gregg Gonsalves @gregggonsalves.bsky.social · 23/06/2026
OK, people. It takes 2 minutes to write a letter to Congress, a few extra if you personalize it. Russ Vought's attempt to take over ALL federal grant funding is anti-democratic and dangerous. We need MORE letters. Let's tip it over 2000 today. actionnetwork.org/letters/oppo...
actionnetwork.org
Oppose OMB Proposal to Put ALL Federal Government Funding Decisions in the Hands of Political Appointees
On May 29, 2026, the Office of Management and Budget issued a Notice of Proposed Rulemaking (NPRM), OMB-2026-0034, Regulation for Federal Financial Assistance. The scope of this proposed regulation is...
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Colette Delawalla, PhD @cdelawalla.bsky.social · 22/06/2026
If researchers can’t share their findings, are we really free? THIS is what I mean when I say science is a core pillar of democracy.
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Laura Haynes👩‍🔬⚾️🐾💙 @drlaurahaynes.bsky.social · 22/06/2026
Important thread about the impact of this administration on science in America…thanks @drdind.bsky.social 👇🏽👇🏽👇🏽
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Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 21/06/2026
“Reevaluating every research grant w/ a political lens each time a new party is in power could end America’s scientific progress and leadership.” China now leads R&D investment. The EU courts US scientists w/ promises of stability that is lacking here. The threat is real. 🧪 archive.today/5T64n
statnews.com
I’ve spent 40 years in research. I have never seen a threat to science like the new grantmaking rule
“American science is too valuable to be turned into a political football,” writes David J. Skorton, president of the Association of American Medical Colleges.
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