Excited to share our latest work - a collaboration with the Cowell lab at UAB and many others. A shout out Sushmita, Alana, Ray, Xiaraon and many others for their hard work...
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Novel Roles for the Ectoenzyme CD38 in the Maintenance of Transcriptional and Metabolic Homeostasis in Astrocytes
CD38 deficiency influences brain NAD/NAM metabolism.
Global CD38 deficiency drives changes in astrocyte mitochondrial, metabolic, senescence, and neurodegenerative-related genes.
CD38 deficiency...