The prion concept postulates that seeded aggregation results in the recruitment of soluble protein monomers and their assembly into amyloid filaments with the same structures as those of the seeds. He...

The Baumgarten Lab at the Institute Pasteur in Paris, France, is looking for a PhD student to join our “Parasite RNA Biology” research group. The position is intended for a student holding a MSc degre...

At first glance, the Cornell University looks like a picture-perfect college brochure. But students say the mood on campus has turned somber amid allegations of sexual assault at a fraternity house.

PDB-101: Training, Outreach, and Education portal of RCSB PDB

Acanthamoeba castellanii, a pathogenic amoeba, belongs to an evolutionary branch distinctly removed from humans and fungi. Cryo-EM of the organism’s ATP synthase enzyme using raw mitochondrial lysates...

This study explores the use of graphene reservoirs formed over perforated supporting films as a method to precisely control ice thickness during cryo-EM sample preparation.

It's International Ataxia Awareness Day.

In eukaryotes, ribosome biogenesis initiates within the nucleolus, a hallmark multilayered compartment of the nucleus. Structures of pre-ribosomes have been characterized ex situ, but their assembly p...

Researchers have uncovered new details about a key norovirus protein. They provide a new framework for future research into the virus and antiviral drugs.

Postdoctoral Scientist Salary £42,694 per annum Fixed term, 3 years MRC Laboratory of Molecular Biology, Cambridge, UK To work in the group of Dr M...

SUMOylation is an essential eukaryotic ubiquitin-like post-translational modification that plays a central role in the regulation of various nuclear processes and stress responses. It canonically occu...

YouTube video by Sholto David

eBIC (Diamond light source) has partnered with the Astbury Biostructure Lab (University of Leeds), the Scottish Centre for Macromolecular Imaging (University of Glasgow), Midlands Regional Cryo-EM Fac...

Concept Life Sciences seeks a Principal Scientist to lead structural biology projects, specialising in X‑ray crystallography and Cryo‑EM. The role is hands‑on, client‑focused, and involves mentoring, ...

<p>The EMBL Imaging Centre in collaboration with the Heidelberg University is offering a 5-day autumn school covering all aspects of the single particle cryo-EM workflow. The autumn school will focus…

Nature Structural & Molecular Biology, Published online: 01 September 2026; doi:10.1038/s41594-026-01870-zProteasomes are essential for male fertility. Kolata, dos Santos, Dendooven and colleagues show large nuclear proteasomal assemblies segregated from DNA in human sperm, forming after meiosis and with a unique α4s isoform. A native substrate is bound at the 20S catalytic site.