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pilarcossio.bsky.social

@pilarcossio.bsky.social
322 followers 104 following 33 posts
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pilarcossio.bsky.social @pilarcossio.bsky.social · 30/09/2026
*Job alert*: Postdoc position at the Flatiron Institute to work on biophysical inference and cryo-EM. ❄️ 🔬Applications are welcome! apply.interfolio.com/193799
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Jerelle Joseph @jerelleaj.bsky.social · 08/09/2026
📣There is still time to nominate someone for a #BPS theory and computation subgroup award! See more details here: drive.google.com/file/d/17aUc...
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 08/09/2026
In 2017 I co-organized a BPS thematic meeting on Conformational Ensembles from Experimental Data and Computer Simulations We're back in Berlin Aug 2027 with Biomolecular Dynamics: Integrating Experiments and Computation with a great line-up (to be revealed soon) www.biophysics.org/upcoming-the...
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pilarcossio.bsky.social @pilarcossio.bsky.social · 05/09/2026
🧨🥵🥵Don’t miss the deadline for the @biophysicalsoc.bsky.social Theory & Computation Awards Sept 15! 🥵🥵🚀 The award will recognize outstanding Postdocs, Early Career and Mid-Career scientists in the field of computational biophysics. www.biophysics.org/Awards-Funding
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pilarcossio.bsky.social @pilarcossio.bsky.social · 05/09/2026
Very excited to share my first blog post with @minhuanli.bsky.social @emilthomasen.bsky.social 🎉 Can we capture an ensemble? Lessons learned from averages and single-molecule measurements in structural biology. rs-station.github.io/2026/08/31/a...
rs-station.github.io
Are We Capturing the Ensemble? | RS Station
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pilarcossio.bsky.social @pilarcossio.bsky.social · 07/08/2026
⚡ Time is running out! ⚡ The deadline for the @biophysicalsoc.bsky.social Theory & Computation Awards is Sept 15! 🧬💻 Recognizing outstanding research across: 🎓 Postdocs 🌱 Early Career 🚀 Mid-Career Nominate a student or colleague! 🧪✨ 👇 Details: www.biophysics.org/Awards-Fundi...
biophysics.org
Subgroup Awards - The Biophysical Society
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Reciprocal Space Station @rs-station.bsky.social · 21/07/2026
1/ We're excited to announce that @rs-station.bsky.social is joining the Open Molecular Software Foundation @omsf.io!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 17/06/2026
*Preprint Alert*: How do we measure resolution when biomolecules won't sit still? 🔬 Estimating it for a static cryo-EM reconstruction is standard. But what about a conformational ensemble? arxiv.org/abs/2606.14449 with the amazing henryhmattingly.bsky.social and @lukeevanshandle.bsky.social #cryoEM
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Simons Foundation @simonsfoundation.org · 28/04/2026
@flatironinstitute.org senior research scientist Pilar Cossio builds crucial tools to reveal how environmental changes alter the behavior of RNA: bit.ly/48rCAg2 #science #biology
bit.ly
Pilar Cossio: Reconstructing RNA’s Shapeshifting Behavior
Flatiron Institute researcher Pilar Cossio builds tools to analyze experimental measurements and reveal how environmental changes alter the behavior of RNA molecules.
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pilarcossio.bsky.social @pilarcossio.bsky.social · 29/04/2026
Very excited to share MIMIC: check it out! An amazing team effort!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 25/04/2026
Excited so share our theoretical work on cryo-EM vitrification and recovering ensemble distributions!!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 13/04/2026
*postdoc job alert* Are you interested in theory and experiment for time-resolved cryo-EM? If so see below 👇 a collaboration between the Crick and the Flatiron Institutes 💻🔬
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Flatiron Institute @flatironinstitute.org · 05/04/2026
#FlatironCCM researchers have developed a new tool called ROCKET that extends the capabilities of AlphaFold by directly learning from raw experimental data: bit.ly/4dUTZkG #science #math
simonsfoundation.org
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Data
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Data on Simons Foundation
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pilarcossio.bsky.social @pilarcossio.bsky.social · 25/03/2026
Celebrating #BiophysicsWeek T&C partnered with Phase Space Invaders podcast: Robert Best @sonyahanson.bsky.social @xuhuihuangchem.bsky.social and host @milosz-wieczor.bsky.social Episode 32: Driving the Future of Biophysics: What’s Next in Theory and Computation? www.buzzsprout.com/2313153/epis...
buzzsprout.com
Episode 32 - Robert Best, Sonya Hanson, Xuhui Huang: Driving the Future of Biophysics. What’s Next in Theory and Computation? - Phase Space Invaders (ψ)
With the convergence of data, computing power, and new methods, computational biology is at its most exciting moment. At PSI, we're asking the leading researchers in the field to discover where we're ...
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pilarcossio.bsky.social @pilarcossio.bsky.social · 22/02/2026
Check out our Flatiron team @BPS2026!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 20/02/2026
How can we extract unbiased transition rates from ligand-unbinding Random Acceleration MD (RAMD) simulations? Our new paper lays out the theoretical framework behind RAMD. Take a look! doi.org/10.1063/5.03... @benoitroux.bsky.social @yiweiding.bsky.social & Alessia Ghidini #MD #drugdiscovery
doi.org
A theoretical framework for random acceleration molecular dynamics simulations
The dissociation of a ligand bound to a receptor is a rare event occurring on a timescale that is far longer than can be afforded by standard simulation methodo
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pilarcossio.bsky.social @pilarcossio.bsky.social · 10/02/2026
#BPS2026 The T&C subgroup is hosting a fun event on Saturday evening, Feb 21st 🎉 Open bar for 2 hours + food! Tickets are selling fast, so sign up soon: www.biophysics.org/2026meeting/...
biophysics.org
BPS2026 Annual Meeting Subgroup Dinners| Biophysical Society
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Miro Astore @miroastore.bsky.social · 04/02/2026
Go use cryojax ! It's awesome! I can't wait to see what people do with it.
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pilarcossio.bsky.social @pilarcossio.bsky.social · 24/01/2026
I finally made my webpage, check it out: pilarcossio.org
pilarcossio.org
Dr. Pilar Cossio - Research Scientist
Senior Research Scientist at Flatiron Institute. Research in computational biology and biophysics.
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pilarcossio.bsky.social @pilarcossio.bsky.social · 03/01/2026
Happy new year!!🎆 & checkout our new preprint exploring optimal transport for cryoEM parameter optimization:
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pilarcossio.bsky.social @pilarcossio.bsky.social · 05/12/2025
Happy to share our cryoEM Ensemble Optimization method! 🎉It infers optimal structures and their weights directly from individual cryoEM images - no maps just physics! with David Sliva-Sánchez, @erikhthiede.bsky.social & Roy Lederman www.biorxiv.org/content/10.6...
biorxiv.org
Cryo-electron microscopy ensemble optimization using individual particles and physical constraints
Biomolecules are inherently dynamic, and understanding their conformational ensemble distributions is essential for understanding their dynamics and biological roles. Cryo-electron microscopy (cryo-EM...
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pilarcossio.bsky.social @pilarcossio.bsky.social · 15/11/2025
Checkout our cryo-EM simulator in JAX: paving the way for cryo-EM probabilistic modelling & statistical structural biology #cryoEM with @m0bri3n.bsky.social @miroastore.bsky.social + Harvard, Flatiron & Cornell!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 22/10/2025
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: pcossio@flatironinstitute.org
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pilarcossio.bsky.social @pilarcossio.bsky.social · 21/10/2025
Submit your BPS T&C subgroup nominations::!!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 19/09/2025
*Job Alert*: postdoc positions available @flatironinstitute.org in Computational Mathematics: apply.interfolio.com/173401
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pilarcossio.bsky.social @pilarcossio.bsky.social · 24/07/2025
Check out our latest preprint for the first community #cryoEM heterogeneity challenge 🎆🎇 @sonyahanson.bsky.social @miroastore.bsky.social + method developers and participants! @flatironinstitute.org
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pilarcossio.bsky.social @pilarcossio.bsky.social · 10/07/2025
#BPS2026 submit your nomination for the Theory and computation awards!!!
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pilarcossio.bsky.social @pilarcossio.bsky.social · 30/03/2025
Check out our recent preprint 👇on counting particles to estimate populations in #cryoem: noise can bias the estimates; with Luke Evans & a great team.
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 29/03/2025
If you care about how to use cryoEM to estimate conformational ensembles and populations of different states you should read this from @pilarcossio.bsky.social and team ❄️ 🔬
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pilarcossio.bsky.social @pilarcossio.bsky.social · 20/03/2025
#APSSummit25 come to our session in generative modeling and machine learning in chem phys! Chaired with @GrantRotskoff and an amazing set of speakers 🎉 starting Thursday 11:30am room 204A
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pilarcossio.bsky.social @pilarcossio.bsky.social · 18/02/2025
#BPS2025 waiting for the national lecture 🥳 @giuliapalermo.bsky.social @labvanni.bsky.social @sriraksha.bsky.social @sesamedusa.bsky.social
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Oli Clarke @olibclarke.bsky.social · 17/02/2025
Thanks to all who attended the #BPS2025 #cryoem symposium yesterday, and the happy hour last night! We heard some superb science at the symposium and had some great discussions which were continued in the evening. And congratulations to Dr. Elizabeth Wright, our inaugural Almeida Award winner!
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Greg Bowman @drgregbowman.bsky.social · 16/02/2025
Nice time catching up with folks from @foldingathome.org at #bps2025
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Sonya @sonyahanson.bsky.social · 17/02/2025
We are hiring a Flatiron Research Fellow in the Structural Molecular Biophysics team! Experience with cryoEM and/or membrane protein simulations are a plus! Happy to chat in person with anyone at #bps2025 ! apply.interfolio.com/160227
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pilarcossio.bsky.social @pilarcossio.bsky.social · 15/02/2025
Checkout the Flatiron Institute Structural and Molecular Biophysics at #BPS2025 @sonyahanson.bsky.social @miroastore.bsky.social @samsl.io
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pilarcossio.bsky.social @pilarcossio.bsky.social · 15/02/2025
For those at #BPS2025 come to the #cryoem subgroup symposium Saturday 8:30-12:30am Room 515B. 🔬❄️There are also tickets available for the happy hour!
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 10/02/2025
Looking forward to great science and cool scientists at #BPS25 next week And before that a stopover in NYC 🍎 to give a talk at the Flatiron Institute and meet @pilarcossio.bsky.social and colleagues
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Bronwyn Lucas @bronwynalucas.bsky.social · 18/01/2025
New metric for calling significant detections of proteins in cryoEM images with 2DTM. Driven by Kexin Zhang in @grigoriefflab.bsky.social in collaboration with @pilarcossio.bsky.social
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Oli Clarke @olibclarke.bsky.social · 17/12/2024
1/ Thrilled to announce Dr. Elizabeth Wright as the inaugural winner of the June Almeida Award for #cryoem! 🎉Elizabeth’s pioneering work in both cryo-ET methods and structural virology made her a perfect fit for this award. Congrats, Elizabeth!
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Syma Khalid @sykhalid.bsky.social · 17/12/2024
As a current IDEA scholar, I can thoroughly recommend the program! Interact with bright minds, kind, inclusive scientists via visits to @flatironinstitute.org in New York City. What’s not to like?
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pilarcossio.bsky.social @pilarcossio.bsky.social · 13/12/2024
#NeurIPS2024 check out our work: Cryo-EM images are intrinsically low dimensional at the MLSB workshop with Luke Evans, Octavian-Vlad Murad @larsdingeldein.bsky.social @rocovino.bsky.social & Marina Meila www.mlsb.io/papers_2024/...
mlsb.io
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pilarcossio.bsky.social @pilarcossio.bsky.social · 07/12/2024
Happy to be part of this & my first post on 🦋 👋
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