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Kasinath-Lab

@kasinath-lab.bsky.social
23 followers 12 following 2 posts
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Kasinath-Lab @kasinath-lab.bsky.social · 11/09/2026
🚨🚨Another New preprint from the lab🚨🚨 MeCP2 is a key regulator of gene silencing. Over 800 different mutations in the X-linked MECP2 gene are known to cause Rett Syndrome. We ask how MeCP2 engages with nucleosomes & how variants affect engagement with chromatin. www.biorxiv.org/content/10.6...
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Kasinath-Lab @kasinath-lab.bsky.social · 04/09/2026
🚨🚨New preprint from ***Outstanding*** graduate student Jessica Song 🚨🚨 Jessica determined several cryo-EM structures (one at 2.5 Å) capturing, for the first time, protein recognition of a pUG-fold RNA & revealing how pUG-fold RNA inhibits DNMT1 activity through multiple modes. tinyurl.com/398ukze9
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