The Life Sciences Departments in Harvard Faculty of Arts and Sciences seek to recruit a tenure-track professor whose research is at the interface of AI and life sciences, from methodological developme...

University of California, San Diego is hiring. Apply now!

Using quantitative live imaging, Green et al. show that proneural gene expression is biased by positional cues and that Notch is activated only after neuroblast selection in the Drosophila embryo. Thi...

In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing ...

You can see AI everywhere except in the productivity statistics

Protein language models have excelled at modeling individual proteins, but extending these capabilities to protein complexes remains a major challenge. MSA Pairformer, a parameter-efficient protein la...

npj Digital Medicine - Rethinking bioinformatics expertise in the era of artificial intelligence

Experiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transit...

Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

What OMB’s Proposed Federal Financial Assistance Rule Means in Practice

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Reminder Definition of Foreign Components NOT-OD-26-084. NIH

The main purpose of this job is to bring cutting-edge light microscopy research approaches to Brandeis researchers and oversee the day-to-day operations of the Brandeis light microscopy facility. The ...

NIH, NASA grantees are confused and concerned amid agencies’ piecemeal communication

Cell behaviors in multicellular organisms are coordinated via both diffusible molecules and by signals based on direct cell–cell contacts. The mode...

Here they show that, in Drosophila testes, Notch functions as a ligand to activate Draper-dependent signalling in neighboring phagocytes and eliminate germline progenitors, revealing Reverse Notch sig...

In her new book, New York Times investigative journalist Jodi Kantor has set her mind to helping young people find their life’s work. What should they, or anyone else who feels lost and overwhelmed right now, do to get started?

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Continuation of Modifications to Peer Review Practices NOT-OD-26-069. NIH

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Highlighted Article: Multisite phosphorylation is important in the regulation of the Capicua (Cic) repressor by ERK, in part because multiple phosphosites contribute to Cic protein degradation.

Here they show that extended serial somatic cell cloning imposes a threefold increase in de novo mutations compared to natural reproduction, progressively reducing birth rates and ultimately limiting ...