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Helena Cocheme

@cochemelab.bsky.social
341 followers 461 following 38 posts

Group Leader @MRC LMS @Imperial College Lab studying #redox #metabolism #ageing #Drosophila

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Helena Cocheme @cochemelab.bsky.social · 10h
✨Excited to share our latest paper in Aging Cell!✨ "Direct Pharmacological Activation of AMPK Extends Lifespan in Yeast, Worms and Flies" Thanks to all the collaborators who made this multi-organism study possible! 💊🪱🪰🐁⏳ #TeamScience #Drosophila #C.elegans #S.pombe #Ageing doi.org/10.1111/acel...
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 10h
🔋 Scientists have extended lifespan in yeast, worms and flies by activating AMPK, the cells’ equivalent of an ‘energy saver’ mode. In some cases, animals lived over 25% longer. 🔗 Read the publication: onlinelibrary.wiley.com/doi/10.1111/... 🔗 Read our web story: lms.mrc.ac.uk/experts-sign...
onlinelibrary.wiley.com
Direct Pharmacological Activation of <fc>AMPK</fc> Extends Lifespan in Yeast, Worms and Flies
AMP-activated protein kinase (AMPK) is a key evolutionarily conserved sensor of energy homeostasis, which is implicated in metabolic health and disease, as well as in ageing. Here, we show that direc...
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Helena Cocheme @cochemelab.bsky.social · 16/09/2026
💚 Congrats to the lab on winning this year's #LMS #Greening competition! 💚 Thanks to everyone in the group for engaging with this initiative, particularly lab manager Andrea for leading our efforts, and postdoc Nsikan for collecting our prizes! 🌱🌵🌿 #ProudPI #Sustainability
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Helena Cocheme @cochemelab.bsky.social · 15/09/2026
📍 Looking forward to this #Redox #BiochemicalSociety Meeting! 💬 Submit your abstract by 16th Sept (23:59 UK-time) for the opportunity to be considered for an elevated talk! 🌍 Cambridge, UK 🗓️ 16-18 Nov 2026 ⏳ Earlybird deadline: 16 Sept 2026 🌐 bit.ly/Redox-26 #BiochemEvent @biochemsoc.bsky.social
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Helena Cocheme @cochemelab.bsky.social · 14/08/2026
⏰🐥 Reminder that the #SuperEarlybird deadline for registration to this #Redox #BiochemicalSociety Meeting is August 16th (23:59 UK-time) 🫵 💷💳 Save £100 🫰 🗓️📝 Final abstracts are only required by Sept 16th, so you can register now to take advantage of the discount & still submit your abstract later ✍️
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Biochemical Society @biochemsoc.bsky.social · 10/08/2026
For decades, our prestigious #BiochemAwards have recognised rising stars and esteemed scientists for their outstanding contributions to the molecular biosciences and the next generation. Consider those who have made an impact to your career or field, and nominate them: ow.ly/OaJH50ZxWlK 🧪
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Mike Murphy @mitoredox.bsky.social · 10/07/2026
I have two post doctoral positions available in my lab funded by the Wellcome Trust to develop new chemical biology approaches to studying mitochondria. Would suit those with interest in both mitochondria and chemical biology. Advert below-please forward and repost! www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Associate x 2 (Fixed Term)
The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge, wishes to appoint two post-doctoral Research Associates to join the research group of Prof. Mike Murphy at t...
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Alexis Barr @alexisbarr.bsky.social · 21/05/2026
We're looking for a new Roving Research @mrc-lms.bsky.social A unique post for those who love research, learning new techniques & working across different teams. Must be a great communicator & well organised! Apply by 21 June: fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com
Investigator Scientist Roving Researcher
Investigator Scientist (Roving Researcher) (LMS 2369) Salary £42,159 – 44,801 plus London Allowance (£5,560) per annum | 2 years fixed term | Full time | Closing Date: 21 June
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Helena Cocheme @cochemelab.bsky.social · 15/05/2026
📍 Registration is now open for this #Redox #BiochemicalSociety Meeting! Excellent invited speakers, plus many slots for elevated talks from abstracts, including #ECRs 🫵 🌍 Cambridge, UK 🗓️ 16-18 Nov 2026 ⏳ Super early bird deadline: 16 Aug 2026 🌐 bit.ly/Redox-26 #BiochemEvent @biochemsoc.bsky.social
bit.ly
Redox – The Good, The Bad and The Unexpected
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 29/04/2026
Are you in human physiology and thinking about starting your own research group? This is a great chance to take that next step at the LMS! 👇 📅 Deadline: 4 May Please share with anyone who might be interested! #HumanPhysiology #AcademicJobs #ResearchCareers #STEM
lms.mrc.ac.uk
Programme Leader Track - MRC Laboratory of Medical Sciences
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Helena Cocheme @cochemelab.bsky.social · 17/03/2026
📢 Calling all #Redox #ECRs! 🗓️ Submit your abstract to the upcoming #GRS 2026 by April 5th to be considered for a talk! 👇 #Thiol #Signaling #GordonResearch
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Mothers in Science @mothersinsci.bsky.social · 16/03/2026
Applications are open for our Caregiver Travel Grant 2026! Apply now for a chance to receive flexible funding to cover caregiving expenses while attending an in-person scientific conference! Apply: www.mothersinscience.com/caregiver-… 📅 Deadline: April 26, 2026 #WomenInSTEM
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Daphne Jackson Trust @daphnejacksontr.bsky.social · 26/02/2026
Thank you for sharing your Daphne Jackson Fellowship journey, Dr Julia Riedl. Her return to crucial research wouldn't be possible without the support of her host; MRC Laboratory of Medical Sciences (LMS), and her funders The Royal Society. #ResearchReturners
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Helena Cocheme @cochemelab.bsky.social · 01/12/2025
✨Featuring our very own Claudia @claudialennicke.bsky.social from the Cochemé lab! ✨ #Redox #Ageing #ProudPI
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 20/11/2025
📣 We’re hiring 6 new Team Science postdocs! Our Team Science approach brings together interdisciplinary researchers to tackle questions no single field can solve alone. Find out more and download our brochure below
lms.mrc.ac.uk
MRC Postdoctoral Research Scientists x 6 - MRC Laboratory of Medical Sciences
Team Science Project
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Michelle Arbeitman @marbeitman.bsky.social · 20/11/2025
The FlyBoard is happy to announce the call for nominations for the Drosophila Community Service Award. Please submit your nomination by 01/16/2026 by email to: drosophilaserviceaward@gmail.com. Please repost.
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 19/11/2025
We’re excited to share that we’ve been awarded £1 million from the Medical Research Council to strengthen partnerships between researchers and industry – helping turn discovery science into real-world health innovations. #LifeSciences #Innovation #LondonLifeSciencesWeek
lms.mrc.ac.uk
LMS awarded £1m to boost life science partnerships in White City
The Medical Research Council (MRC) has made a major investment in a series of industry collaborations with eight diverse teams from the MRC Laboratory of Medical Sciences (LMS) to accelerate innovatio...
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Nature @nature.com · 29/10/2025
Funders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake go.nature.com/47zrzYZ
go.nature.com
From MRI to Ozempic: breakthroughs that show why fundamental research must be protected
In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.
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SFRR-E_ ECRs @sfrre-ecr.bsky.social · 26/10/2025
⚡️PhD Relay Race is coming! Ready to submit your abstract? 🗣️Your flashtalk = 5 min → keep it punchy, clear & exciting. 🎯Think of it as your pitch to the redox crowd! 🚨Deadline: Friday 31 Oct #phd #science #redox #abstract #tips
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Helena Cocheme @cochemelab.bsky.social · 21/10/2025
'Reaffirming the value of model organisms in training scientific minds' Comment by M. Yang & Z. Du, published in @natcellbio.nature.com doi.org/10.1038/s415...
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Mothers in Science @mothersinsci.bsky.social · 21/10/2025
Join us tomorrow to hear Dr Isabel Torres speaking live on maternity bias in STEMM. 📢 Spread the word & share your story anonymously to help us raise awareness: forms.gle/y99a5RnBCD879c1P6 Register now👇https://www.mothersinscience.com/scimomchats #BreaktheBiasSTEMM
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SFRR-E_ ECRs @sfrre-ecr.bsky.social · 17/10/2025
🎯✨ ECR Webinar: Career Transitions 🗓 Tue 21 Oct | 15:00 CEST 📍 Zoom | ID: 864 6973 1540 | PW: 433382 🔬💼 Hear diverse career stories from researchers! 🚨 Save the date & join us! #SFRRIWebinars #ECR #ScienceCareers
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Alberto Sanz @albertosanzmon1.bsky.social · 17/10/2025
There is a PhD Studentship in my laboratory starting in March 2026. Please contact me if you are interested. www.findaphd.com/phds/project...
findaphd.com
FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow on FindAPhD.com
PhD Project - FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow, listed on FindAPhD.com
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Nils Burger @nilsburger.bsky.social · 16/10/2025
Excited to share that we are hiring a research assistant for my lab at UTSW in Dallas (www.nils-burger-lab.com). Please share with your mentees. utsw.taleo.net/careersectio... We are also looking for motivated, curious, and enthusiastic postdoctoral fellows!
utsw.taleo.net
Research Assistant I, Pharmacology
Click the link provided to see the complete job description.
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Helena Cocheme @cochemelab.bsky.social · 06/10/2025
Great to participate at #EDRC2025, which gathered together an impressive 750 researchers from 40 countries! 🌍🪰🔬 With strong representation from the #LMS by Nsikan, Miriam & Isabel ⭐ #Drosophila #Redox #Ageing #Cancer #DiseaseModels
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 02/10/2025
The LMS has achieved Gold LEAF accreditation for sustainability! 🏅 From smart lab booking systems to energy-saving tech and zero-waste practices, we’re working hard to cut our environmental footprint while supporting world-class research! 🌍 #Sustainability #LEAF #GoldAward
lms.mrc.ac.uk
LMS receives gold award for sustainability
Achieving Gold LEAF accreditation marks a significant milestone in our commitment to making research at the MRC Laboratory of Medical Sciences (LMS) more sustainable and signals the start of an ongoin...
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SFRR-E_ ECRs @sfrre-ecr.bsky.social · 01/10/2025
🚨 Call for Abstracts! 🎓 3rd PhD Symposium: Redox Relay Race 🧬 PhD students in redox biology – apply now! 🎤 5-min flashtalk + 2-min Q&A 📅 Online: 18 Nov 2025 📧 Send abstract (max 300 words) to ecr@sfrr-europe.org by 24 Oct #RedoxBiology #PhDSymposium
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David Weinkove @dweinkove.bsky.social · 29/09/2025
Please help spread the word about our inaugural public lecture on Wednesday. Sign up and if you are in the ageing field it’s a great opp for your family to finally understand what you do! 😀 Thanks for your support 🙏 bsra.org.uk/events/bsra-...
bsra.org.uk
BSRA Online Public Seminar Series - BSRA
In our new Understanding Ageing: Meet the Scientists series, we’ve invited experts in their field to talk about their research and what it means for each of us as we get older. You don’t need any scie...
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Helena Cocheme @cochemelab.bsky.social · 26/09/2025
✨ #Postdoc Nsikan Nsek giving an excellent presentation of his research on #Drosophila #Ageing #Cancer at the #EDRC2025! ✨ #RoyalSocietyCDF #LMSonTour #ProudPI @mrc-lms.bsky.social @royalsociety.org
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Helena Cocheme @cochemelab.bsky.social · 25/09/2025
Arrived in Alicante, and excited for this year’s #EDRC2025! 🪰🧪🔬🧫🥼🧬🪰 The #LMS is well represented at the meeting - catch us at our talk/poster presentations! #Drosophila #Redox #Ageing #DiseaseModels #Cancer #Obesity @mrc-lms.bsky.social
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Helena Cocheme @cochemelab.bsky.social · 16/09/2025
"Microbial allies: bacteria help fight against cancer" ✨ News story from #LMS @mrc-lms.bsky.social, covering the beautiful study led by #postdoc Daniel Martinez @dmartimarti.bsky.social - congrats! ✨ #PostdocAppreciationWeek #PAW2025 #Cancer #Microbiome #Chemotherapy lms.mrc.ac.uk/microbial-al...
lms.mrc.ac.uk
Microbial allies: bacteria help fight against cancer
An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated w...
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FlyBase @flybase.bsky.social · 16/09/2025
The FlyBase situation has made the national news www.nbcnews.com/science/scie...
nbcnews.com
Trump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit fly
This spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard.
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 12/09/2025
Can microbes enhance chemotherapy? A new paper from the LMS shows how the tumour-associated microbiome can impact the efficacy of chemotherapy drugs. #medsky #cancer #biomed
cell.com
Chemotherapy modulation by a cancer-associated microbiota metabolite
Martinez-Martinez et al. combine a host-microbe-drug-nutrient screen with multi-omics to reveal how the cancer-associated microbiota modulates chemotherapy. They identify 2-methylisocitrate, a microbi...
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Helena Cocheme @cochemelab.bsky.social · 10/09/2025
🚨New paper published today on cancer bugs and drugs!🚨 “Chemotherapy modulation by a cancer-associated microbiota metabolite” Congrats to the Cabreiro lab on this exciting study! #Cancer #Microbiome #Metabolism #Chemotherapy #MRC_LMS #ImperialCollege #CECAD_Cologne www.cell.com/cell-systems...
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 04/09/2025
We’re seeking a highly skilled and motivated candidate to lead the LMS Bioinformatics Facility. Find out more and apply now by following the link below! #Bioinformatics #Hiring #NowHiring #CareerOpportunities #Jobs
lms.mrc.ac.uk
Head of Bioinformatics - MRC Laboratory of Medical Sciences
We are recruiting for a Head of Bioinformatics to lead our Bioinformatics facility
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Marc Dionne @marcsdionne.bsky.social · 18/08/2025
Come be my colleague! We have three open positions at the Assistant/Associate Professor level for candidates in all areas of the biological sciences. www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Ilan davis @ilandavis.bsky.social · 17/08/2025
Dear friends and scientific colleagues, (especially those of you who knew David Ish-Horowicz). Feel free to share the attached PDF widely (all the speakers are happy for the talks to be shared). Many thanks Best regards Ilan www.youtube.com/playlist?lis...
youtube.com
David Ish-Horowicz memorial symposium, Francis Crick Institute, London, 23 June 2025. - YouTube
A public symposium organised by friends, scientific colleages and David's wife Ros Diamond to cellebrate David Ish-Horowiccz's, FRS, scientific achievements,...
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Helena Cocheme @cochemelab.bsky.social · 15/08/2025
Thanks for posting these photos - really enjoyed participating at the #GERF2025 festival this summer! Our #FutureFoodLive demo featured PhD student alumnus Eliano and his research on #pH in #ageing, as well as delicious pretzels baked live on stage! 🥨👨‍🍳🥼🧪👩‍🔬
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Helena Cocheme @cochemelab.bsky.social · 12/08/2025
📢 Technician vacancy @LMS in London! Join us and support the research of 2x clinician scientists. 🗓️ Applications close 21st August
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Vicki Metzis @vmetzis.bsky.social · 01/08/2025
Application deadline for up to 5 @mrc-lms.bsky.social postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!
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Helena Cocheme @cochemelab.bsky.social · 27/07/2025
Join the #LMS! Our institute is advertising for junior #GroupLeader positions in #Physiology and #Metabolism. Closing date for applications: August 31st!
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corderolab.bsky.social @corderolab.bsky.social · 21/07/2025
Very happy and proud to share the latest work from our lab. Neuroendocrine control of intestinal regeneration through the vascular niche. www.sciencedirect.com/science/arti...
sciencedirect.com
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila
Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…
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Genetics Society of America @genetics-gsa.bsky.social · 15/07/2025
Discover how fruit flies are unlocking the secrets of human disease! 🧬 Join 2025 GSA Early Career Medal recipient Shinya Yamamoto of ‪@bcmhouston.bsky.social on July 24, 2–3 p.m. EDT, for a seminar on gene discovery & collaboration. 🔗Register now: buff.ly/nJnvoMt
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Jenny Regan @jennyregan.bsky.social · 11/07/2025
New preprint - varied routes to ⬆️ infection susceptibility over age - via bona fide immunosenescence, but also often via reduced tolerance 🪰🕰️🦠☠️ ⬆️ risk to die from infection predicts lifespan in males. Great group effort from the lab! www.biorxiv.org/content/10.1...
biorxiv.org
Different ways to die: harnessing variation in Drosophila reveals loss of tolerance and resistance over age and sex-specific association between infection susceptibility and lifespan
It is widely accepted that susceptibility to infection increases with age. The reason often invoked is the dysregulation of the immune system, which is both cause and consequence of ageing. However, w...
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 09/07/2025
A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue. A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
lms.mrc.ac.uk
Study reveals the hidden benefits of weight loss on fat tissue
Scientists from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have produced the first detailed characterisation of the changes that weight loss causes in human fat tissue by...
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delladavid-lab.bsky.social @delladavid-lab.bsky.social · 04/07/2025
We are hiring a research assistant 👉 tinyurl.com/yxebtjbj to join our lab working on healthy #ageing and protein #aggregation in C. elegans 🪱. Deadline August 4th. 🙏 RT. #proteostasis @babrahaminst.bsky.social
tinyurl.com
hireful.
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 04/07/2025
Are you a recent UK graduate without an MSc, eager to launch your career in biomedical research? Apply now for our two-year Science Technology Graduate Programme! You'll gain hands-on experience in state-of-the-art research facilities, build technical expertise and earn a competitive salary.
lms.mrc.ac.uk
Science Technology Graduate Programme - MRC Laboratory of Medical Sciences
Bioinformatics Facility - Dr George Young and Electron Microscopy Facility - Dr Ricardo Aramayo
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Vicki Metzis @vmetzis.bsky.social · 27/06/2025
Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social
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Helena Cocheme @cochemelab.bsky.social · 27/06/2025
Check out the #LMSnews story on the @mrc-lms.bsky.social website about our latest study published in @natcomms.nature.com! Illustrated by multi-talented first author #postdoc #painter @claudialennicke.bsky.social 💛 #redox #cysteine #sciart
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Helena Cocheme @cochemelab.bsky.social · 27/06/2025
🎉Excited to share our latest paper, published in Nature Communications!🎉 "Enhancing autophagy by redox regulation extends lifespan in Drosophila" #redox #metabolism #ageing #Drosophila @natcomms.nature.com @mrc-lms.bsky.social doi.org/10.1038/s414...
doi.org
Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications
Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...
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