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John Tsang

@tsanglab.bsky.social
2.4K followers 945 following 51 posts

Systems immunologist at Yale, @yalecsei.bsky.social‬, @czbiohub.bsky.social‬ Me: medicine.yale.edu/profile/john-tsang Lab: www.tsanglab.org Center: medicine.yale.edu/systems-engineeri…

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John Tsang @tsanglab.bsky.social · 09/06/2026
6th iteration of the Physics & Computation in Immunology meeting will be at Yale CSEI @yalecsei.bsky.social Sep 28–30. With Arup Chakraborty, Michael Lässig, @thearmita.bsky.social & Alex Walczak. Speakers from Princeton, Cambridge, Harvard, MSK, UCSF & more. Free. 120 spots. Deadline Sep 6.
sites.google.com
PCI VI
6th Workshop and Symposium Physics and Computation in Immunology 28 – 30 September, 2026 | Yale University
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Armita Nourmohammad @thearmita.bsky.social · 27/10/2025
excited to announce that this January we are relocating to Yale to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI): @yalecsei.bsky.social looking to hire 2 postdocs to join us in this endeavor. more details can be found here: sites.google.com/uw.edu/statp...
sites.google.com
SPE - join us
Postdoctoral position: In January 2026, we are relocating to Yale university to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI). We are looking for talented postd...
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Fusion Conferences @fusionconf.bsky.social · 08/12/2025
🎉 Big news! We’ve just released the first draft of #CancerImmuno's conference programme! Check out the website to explore what the chairs have been busy organising! Don't forget to register and submit your abstract. Click here to view the programme: bit.ly/4pZwmKQ
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Christiana Fogg @cnfogg.bsky.social · 08/12/2025
An accompanying Focus by John Tsang (@tsanglab.bsky.social) provides a broader perspective of #AI & #immunology. www.science.org/doi/10.1126/...
science.org
AI immunologists are here: Are they ready for prime time?
AI-based tools can help immunologists with a range of tasks but have limitations.
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Human Immunome Project @immunome.bsky.social · 25/11/2025
Hear from investigators including HIP Co-CSO @tsanglab.bsky.social on how AI is changing immunology research, what is necessary to move forward, the potential and the pitfalls, and what will remain unchanged as the field journeys into a new era. www.cell.com/immunity/ful...
cell.com
AI and immunology
AI is rapidly becoming part of many aspects of daily life, with an impact that reaches all fields of research. We asked investigators to share their thoughts on how AI is changing immunology research,...
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Human Immunome Project @immunome.bsky.social · 12/11/2025
Fascinating new podcast on the immune system as the body's early warning system 🧬 @tsanglab.bsky.social (HIP co-CSO) & David Ewing Duncan explain how a blood test could predict disease before you have symptoms The future of catching things early looks really promising! www.npr.org/2025/11/12/n...
npr.org
How mapping the entire immune system could revolutionize medicine : Short Wave
David Ewing Duncan has spent the last 25 years being poked and prodded in the name of science. He’s signed up for hundreds of tests because, as a journalist, he writes about emerging health breakthrou...
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Fusion Conferences @fusionconf.bsky.social · 17/11/2025
#CancerImmuno speaker list is live!📢 Join us in sunny Lisbon, July 2026. Register now and submit your talk to share your research. Early Bird Deadline: 15 Jan 2026 👉 Click here to register: bit.ly/4qZVqmd #FusionImmunology #FusionCancerResearch
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lisago @lisago.bsky.social · 15/10/2025
Notes on a compelling discussion with @tsanglab.bsky.social Genome = blueprint. Immunome = real-time sensor. The "curse of dimensionality" (millions of data points per sample!) meets AI compression. Result? We can finally map the human immune system at scale. @humanimmunomeproject 🚀
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Harmit Singh Malik @harmitmalik.bsky.social · 09/10/2025
Just saw a post which misspelled 'Machine learning' as 'Machine earning', and I wondered if that was a Freudian slip.
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John Tsang @tsanglab.bsky.social · 09/10/2025
woohoo! well done Toronto - brings back childhood memories of the back-to-back world series won by the Jays...
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Human Immunome Project @immunome.bsky.social · 06/10/2025
Big news: We've announced the largest #systemsimmunology collaboration in history! Ten world-class research institutes are joining @immunome.bsky.social in a pioneering plan to understand human immune response variability. www.humanimmunomeproject.org/news/human-i... @tsanglab.bsky.social
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Yale Center for Systems and Engineering Immunology @yalecsei.bsky.social · 10/07/2025
Thank you #CZBiohubNY Mini Workshop presenters and attendees! Great talks by @czbiohub.bsky.social and @yaleschoolofmed.bsky.social scientists. Grateful to #CZI and @tsanglab.bsky.social for bringing us together. Thank you Susan Rosenthal, Elizabeth Ferris and Lital Manor for superb event logistics.
Picture of some of our amazing workshop presenters.
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Yale Center for Systems and Engineering Immunology @yalecsei.bsky.social · 09/07/2025
Exciting lineup at today's #CZBiohubNY Mini Workshop hosted by @yalemedicine.bsky.social, @tsanglab.bsky.social and @yalecsei.bsky.social. Thrilled to welcome @czbiohub.bsky.social and @chanzuckerberg.bsky.social investigators and team members to Yale for this day of science and interaction.
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Ivan Zanoni @lozanzi.bsky.social · 01/07/2025
What an amazing work @iannaconelab.bsky.social &friends just out @natimmunol.nature.com, it was really cool to have a preview of this fantastic work at the 2025 ENII EFIS EJI Summer School! Many congrats Matteo &co! Check it out here 👉 www.nature.com/articles/s41... & here 😉 👇👇👇
nature.com
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming - Nature Immunology
Here the authors show that CD4+ effector T cells prevent or reverse CD8+ T cell dysfunction by licensing Kupffer cells to trigger IL-27 production, defining a liver-specific immune circuit and a poten...
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Ardem Patapoutian @ardemp.bskyverified.social · 25/06/2025
So important! Please contact your Republican senators, especially Sen. Susan Collins (R-ME), Sen. Shelley Moore Capito (R-WV), Sen. Bill Cassidy (R-LA), Sen. Katie Britt (R-AL), and Sen. Dave McCormick (R-PA). 🙏 amplify!
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John Tsang @tsanglab.bsky.social · 22/06/2025
Added a bunch of new folks. Let me know if anyone wants to be added.
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Adrian Liston @labliston.bsky.social · 21/06/2025
Pre-print time! Our new study on #systemsimmunology analysis of #Alzheimers patients is out now on @medrxivpreprint.bsky.social. This is the culmination of a long collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8 www.medrxiv.org/content/10.1...
medrxiv.org
A systems immunology analysis of Alzheimer’s disease reveals an age- and environmental exposure-independent disturbance in B cell maturation
Alzheimer’s disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal models, and clinica...
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oZgun Gokce @gokcegroup.bsky.social · 15/06/2025
Atul Butte’s talk introduced me to systems biology—I was presynapse scientist and opened my horizon to "biomedical moments, thawing frozen discoveries in data". Ideas that changed my career. Thank you for the science, the spirit, and the inspiration. You will be remembered.
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John Tsang @tsanglab.bsky.social · 15/06/2025
Atul has been a constant inspiring force. He is perpetually optimistic and never stops to empower the world with more data and motivate all of us to dig deeper and be more innovative with data. I miss his energy and our conversations. RIP - May memories of Atul continue to inspire us all.
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 05/06/2025
Senate hearing on the FY26 NIH budget with Jay Bhattacharya June 10, 10am ET www.appropriations.senate.gov/hearings/a-r...
appropriations.senate.gov
A Review of the President’s Fiscal Year 2026 Budget Request for the National Institutes of Health | United States Senate Committee on Appropriations
United States Senate Committee on Appropriations
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Calli McMurray @callimcflurry.bsky.social · 04/06/2025
FlyBase, a crucial resource for drosophila research, has lost its funding because its grant is awarded to Harvard. The team is scrambling to find other sources of funds, including donations from labs. Read more: www.thetransmitter.org/community/fl... @flybase.bsky.social
thetransmitter.org
FlyBase funding squashed amid Harvard grant terminations
The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.
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Eric Topol @erictopol.bsky.social · 04/06/2025
My colleague and friend @scripps.edu, @ardemp.bskyverified.social, on the NYT front page today
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Michael Baym @baym.lol · 24/05/2025
I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 24/05/2025
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...
youtu.be
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
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Gc Rox @gcrox.bsky.social · 23/05/2025
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
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Djamel Nehar-Belaid @dnehar.bsky.social · 16/05/2025
7/10 In a combined analysis of infants and previously sequenced adults (generated by @tsanglab.bsky.social lab; PMID:33713619), infants display a similar ISG signature in monocytes but a markedly enhanced ISG signature in T and B cells, which is consistent with infant specific immune features.
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John Tsang @tsanglab.bsky.social · 16/05/2025
Exciting study on infant immune responses to sars-cov-2 and how they compare to adults.
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Djamel Nehar-Belaid @dnehar.bsky.social · 16/05/2025
1/10 I am very excited to share our latest study, now out in @natcomms.nature.com. We applied a multidimensional approach to decipher the immune responses to SARS-CoV-2 infection in 2-month-old hospitalized infants. We analyzed: scRNA-of PBMCs, serum cytokines and antibody responses. rdcu.be/emkNa
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Paul Krugman @pkrugman.bsky.social · 10/05/2025
So let me get this straight: masks are bad and un-American if worn to fight a pandemic, but good if worn by people claiming to be government agents when they kidnap people off the street
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John Tsang @tsanglab.bsky.social · 05/05/2025
Wonderful to catch up with friends and colleagues at #aai2025. Ofer Levy, Mercy Prabhudas, Donna Farber, me, and Bali Pulendran. Adding @lucasite-lab.bsky.social in the second one!
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John Tsang @tsanglab.bsky.social · 04/05/2025
Thanks for the highlight! Yes we are live still great talks to come - come on over to hang out with systems immunologists this morning at #aai2025!
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Jeremy Berg @jeremymberg.bsky.social · 04/05/2025
My interest in math and science was stimulated by an NSF-funded high school summer program, my PhD dissertation research was supported by an NSF fellowship, and some of my most creative research early in my independent career was supported by an NSF award. #WithoutNSF
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Senator Patty Murray @murray.senate.gov · 02/05/2025
NIH's work saves lives—& Trump is gutting it. Straight from D.C. I headed to Seattle Children's to hear from researchers & patients alike about the importance of NIH funding—it's not just about lines in a budget, it's about lifesaving discoveries. We ALL need to speak up to save it.
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John Tsang @tsanglab.bsky.social · 01/05/2025
As always, really enjoyed the science and interactions at #cshlsysimm - a meeting right at the intersection of immunobiology, systems biology, computational modeling, and immune engineering. Great also to catch up with lab alums and so great to see Candace & Kyemyung! C u in 2027 if not earlier.
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John Tsang @tsanglab.bsky.social · 30/04/2025
Excited to share our review/perspective in the Annual Review of Immunology: "Systems Human Immunology and AI: Immune Setpoint and Immune Health"! www.annualreviews.org/content/jour... Congrats to Yona Lei - an MSTP MD/PhD student and budding systems human immunologist in the lab.
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John Tsang @tsanglab.bsky.social · 20/04/2025
Nice explanation of the interactions between tariffs and other key variables www.wsj.com/finance/inve...
wsj.com
Who Will Pay the Price for Trump’s Economic Goals?
Slash the trade deficit and the net inflow of foreign money dries up. This will hit share prices and raise the cost of borrowing for companies.
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John Quackenbush @johnquackenbush.bsky.social · 17/04/2025
I'm a proud Harvard Professor, and the University stands behind academic freedom that powers discovery. Grants are not gifts; they are contracts on which we have to deliver. We work long, hard hours, train students, and return innovation and value to the US. #Harvard www.cnn.com/2025/04/17/u...
cnn.com
iPhones and GPS wouldn’t exist without research funded by the US government. What’s at stake in Trump cuts to university funding | CNN
Imagine a world without the internet, or GPS, MRNA vaccines or the touchscreen on your iPhone. The science and technology that have become integral to our daily lives may never have existed, experts s...
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Roxana Daneshjou, MD, PhD @roxanadaneshjou.bsky.social · 15/04/2025
Stanford’s president and provost release a statement supporting Harvard. stanforddaily.com/2025/04/15/l...
stanforddaily.com
Stanford president and provost back Harvard in funding fight
The president and provost said Harvard’s rejection of government demands was “rooted in the American tradition of liberty.”
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Rose Albert @rosemalb.bsky.social · 10/04/2025
“Investments in science and public health are essential for the future of rural southern states like Mississippi.” Read about my perspectives as a Mississippian and scientist in my recent OpEd : digital.meridianstar.com/The-Meridian...
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 12/04/2025
The Senate Committee on Appropriations is holding a hearing on Biomedical Research: Keeping America’s Edge in Innovation on April 30 at 10:30am ET, chaired by Senator Susan Collins 🧪 www.appropriations.senate.gov/hearings/bio...
appropriations.senate.gov
Biomedical Research: Keeping America’s Edge in Innovation | United States Senate Committee on Appropriations
United States Senate Committee on Appropriations
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Jordan Meier @doc-jlmeier.bsky.social · 10/04/2025
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost. www.training.nih.gov/research-tra...
training.nih.gov
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Kristian G. Andersen @kgandersen.bsky.social · 10/04/2025
I could literally quote every single sentence of this commentary, so I'm not going to - just read the whole thing. And thanks, Dr. Bieniasz, for saying it as it is and showing true leadership. We need that from more scientists and scientific leaders. www.theguardian.com/commentisfre...
theguardian.com
We are witnessing the destruction of science in America | Paul Darren Bieniasz
If we stay on this administration’s course, future life-saving medicines may never be invented
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Science Magazine @science.org · 09/04/2025
Exclusive: Weeks after President Donald Trump’s administration ordered NIH to pull $250 million in biomedical research grants to Columbia University, the agency is freezing all remaining grant money owed to the university until further notice. scim.ag/4if5Rg1
scim.ag
NIH freezes all research grants to Columbia University
Amid negotiations with Trump, the university could risk losing nearly $700 million
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John Tsang @tsanglab.bsky.social · 09/04/2025
Well said. Anything can be discussed and improved, and that’s great and the point of having an open democratic society. But Improving something with a long track record of effectiveness and success wouldn’t need to start with alarming dismantlement. edition.cnn.com/2025/04/09/h...
edition.cnn.com
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
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Roham Parsa @rohamparsa.bsky.social · 07/04/2025
Hi, we are looking for two motivated postdocs to join our group! job-boards.greenhouse.io/chanzuckerbe... job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io
Research Scholar, T cell Tissue Adaptation and Residency (Parsa Group - Biohub NY)
New York, New York, United States
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Tamara Vanderwal @vanderlab.bsky.social · 07/04/2025
Grad student applicants from the US: University of British Columbia (Vancouver, Canada) has re-opened applications for Master's and PhD programs (e.g., biomed engineering, genetics). Info sessions Apr. 15th w/ current US students: www.grad.ubc.ca/us-applicant... Stable, awesome environment!!
grad.ubc.ca
US Applicant Week
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 07/04/2025
Tenure-track Faculty position just opened up in my department! If you want to be part of a dynamic group who is excited about science, apply. For more details, visit www.usherbrooke.ca/emplois/offr... Please share in your networks! #microsky
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André Picard @picardonhealth @picardonhealth.bsky.social · 07/04/2025
Toronto’s University Health Network launches recruitment campaign for scientists. Hospital network will invest $15-million in recruiting 50 scientists as a part of its ‘Canada Leads 100 Challenge,’ by @jenniferyang.bsky.social www.theglobeandmail.com/canada/artic... via @theglobeandmail.com
theglobeandmail.com
Toronto’s University Health Network launches recruitment campaign for scientists
Hospital network will be investing $15-million in recruiting 50 scientists immediately as a part of its ‘Canada Leads 100 Challenge’
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John Tsang @tsanglab.bsky.social · 07/04/2025
Excellent piece on what is at stake: scientific and medical advances that help patients directly and now - wapo.st/42yttHQ
wapo.st
NIH scientists have a cancer breakthrough. Layoffs are delaying it.
A big step forward in cancer therapy has been slowed by layoffs and new restrictions at the National Institutes of Health, where it was developed.
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Sarah Ross @sarahhross.bsky.social · 04/04/2025
#Immunology out now @science.org Regulatory T cells inhibit pain sensing in female, but not male, mice. buff.ly/SKtHnfK By Élora Midavaine, Sakeen Kashem et al.
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