What makes each cell in an individual different despite having the same DNA? Inferring Gene Regulatory Networks (GRNs) for single cells provides an answer, but are the GRN models right? Simple answer: similar cells should have similar networks. #networkmedicine
www.biorxiv.org/content/10.6...
biorxiv.org
FERRET: Framework to Evaluate Robustness in Regulatory Networks Using Heterogeneous Cell Types
Techniques for evaluating gene regulatory network (GRN) inference methods typically focus on recovering small ground-truth networks or on benchmarking against simulated data. However, both approaches ...
