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Fabrice Jean-Pierre

@fabricejpierre.bsky.social
3.7K followers 538 following 229 posts

Assistant Professor @USherbrooke | Polymicrobial biofilms, interactions & mechanisms of recalcitrance | he/him www.fjplab.com scholar.google.ca/citations?user=N5…

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Reposted by Fabrice Jean-Pierre
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 01/10/2026
Work by Kaitlyn Barrack, my former PhD student, was featured on the Small Things Considered blog: smallthingsconsidered.blog/schaechter/2... Here's the link to the paper: pubmed.ncbi.nlm.nih.gov/42262087/ @asm.org #JBacteriol
smallthingsconsidered.blog
Col­ibactin (cont.)
Noteworthy — Now, a link between colibactin production and intestinal dysbiosis in cystic fibrosis patients.
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 02/10/2026
New in JB: Baker, Nizet et al. explore the role of monounsaturated fatty acid biosynthesis in the ability of Streptococcus to deal with envelope homeostasis and stress - highlighting species and context dependence. pubmed.ncbi.nlm.nih.gov/42565831/ @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 02/10/2026
Excited to be part of another collaboration with my colleague Mark Sundrud exploring the impact of bile on immune regulation. This study is lead by Mark's postdoc, Zhiping Xiao. pubmed.ncbi.nlm.nih.gov/42779649/
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 30/09/2026
JB Editor's Pick: Park and Sauer show that the chemosensory protein BdlA relocates to the flagellar pole during dispersion of P. aeruginosa from a biofilm, linking cdG regulation and restored motility. pubmed.ncbi.nlm.nih.gov/42584418/ @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 26/09/2026
Pls share: Two tenure-track positions in Molecular Microbiology at Virginia Tech. I had a great visit there a couple of years ago! jobs.apply.vt.edu/jobs/assista...
jobs.apply.vt.edu
Assistant/Associate Professor - Blacksburg, Virginia, United States
Job Description The Department of Biological Sciences in the College of Science at Virginia Tech seeks applicants for two (2) tenure-track research and teaching positions at the Assistant/Associate ...
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 27/09/2026
Last day of the 2026 UCI World Championships. Allez MVDP!!! #2026UCIchampionships #montreal
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 26/09/2026
Amazing cycling finale. Bravo Demi Vollering!
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 24/09/2026
New in JB: Thanks to all the authors who contributed to the meeting report covering the 10th American Society for Microbiology Conference on Biofilms! Check it out. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Centre SÈVE @centre-seve.bsky.social · 21/09/2026
📢Prolongation de la soumission de résumé 📢Abstract deadline extended 📅2 octobre /October 2nd
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 21/09/2026
New in JB: Ficarrotta, Papin et al. combine 'omics & modeling, plus experiments, to predict and test the metabolism of P. aeruginosa persistors, which are characterized by up-regulation of central metabolism. pubmed.ncbi.nlm.nih.gov/42474335/ @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 15/09/2026
Pls share: Princeton has an open rank faculty search in the areas of cancer biology, cancer prevention, and cancer-relevant computational science, including connections between cancer and immunology or metabolism. apply.interfolio.com/191852
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 11/09/2026
This is nuts! "Antibody data manipulation extends to thousands of images across 15 suppliers" www.chemistryworld.com/news/antibod... #imagemanipulation #imageduplication #theregoesourgrantmoney
chemistryworld.com
Antibody data manipulation extends to thousands of images across 15 suppliers
Sleuths discover widespread, systematic alteration of Western blots and other antibody data
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 09/09/2026
JB Editor's Pick: Guo, Jung et al. show acetic acid and other SCFA, key molecules in the gut, via the tRNA-modifying MnmG/MnmE pathway, are potent inducers of the glutamate-dependent acid resistance system in E. coli. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 11/09/2026
Really important from @ellinoralseth.bsky.social & @brownlab.bsky.social - a framework for defense as an evolved adaptation, in a world where ‘defense’ & ‘immune’ are often used to mean anti-infection The bacterial immune system: identifying evolved defense adaptations www.cell.com/trends/micro...
cell.com
The bacterial immune system: identifying evolved defense adaptations
Recent years have witnessed a rapid expansion in bacterial defense mechanisms. Alongside established defenses against molecular parasites, hundreds of novel mechanisms are being described annually, co...
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John Helmann @johnhelmann.bsky.social · 09/09/2026
Most cells require carbonic anhydrase and/or bicarbonate import to sustain pools of soluble inorganic carbon (SIC=CO2+HCO3-). Here, we identify proteins required for SIC homeostasis in Bacillus subtilis and identify a mutation that bypasses their requirement. www.biorxiv.org/content/10.6...
biorxiv.org
Physiological Roles of Carbonic Anhydrases and an MpsAB-like Bicarbonate Transporter in Bacillus subtilis
Carbonic anhydrase (E.C. 4.2.1.1) is an enzyme that catalyzes the reversible hydration of CO2 to carbonic acid (H2CO3), which dissociates to bicarbonate (HCO3-) at intracellular pH. Copious amounts of...
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 08/09/2026
New in JB: Rangarajan and Waters review the role of divalent metals, particularly Mn2+, Mg2+, Zn2+, Ca2+, and Fe2+, in c-di-GMP signaling, including how these metals impact DGC and PDE enzyme activity. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Johannes Cairns @jcairns.bsky.social · 06/09/2026
Wanna become professor in medical bacteriology at Uppsala? www.uu.se/en/about-uu/...
uu.se
Professor in Medical Bacteriology - Uppsala University
Professor in Medical Bacteriology, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 04/09/2026
JB Editor's Pick: Schutz, Wargo et al. used a genetic screen, coupled with clean deletions, to define the suite of genes impacting the production of the hemolytic phospholipase C/sphingomyelinase (PlcH) of P. aeruginosa. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 01/09/2026
New in JB: Cao, Ye & Pan review the role of metagenomics in tracking Abx resistance, offering a practical framework for using metagenomics as a useful tool. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 02/09/2026
JB Editor's Choice: Nies, Große et al. profile the trxnal start sites of Cupriavidus metallidurans and found that >80% of genes are transcribed by RpoD-dependent RNA polymerases, & up to 65% of genes impacted by metals. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 02/09/2026
Our special issue on the social lives of bacteria is out today 🎉 it was a pleasure to edit this collection over the last year with @friendlymicrobe.bsky.social. Read our editorial here: portlandpress.com/essaysbioche...
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Patrick R. Secor @prsecor.bsky.social · 02/09/2026
This job ad is now live! Please share or apply here: jobs.montana.edu/postings/52780 Screening of applicants begins Sept 15, 2026 #MicroSky #PhageSky #ScienceJobs
jobs.montana.edu
Postdoctoral Researcher - Lyme Disease Bacteriophage Biology
The Secor Lab seeks a postdoctoral researcher to investigate bacteriophage biology in the Lyme disease spirochete Borrelia burgdorferi. The successful candidate will help define how phiBB-1 controls h...
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 01/09/2026
There are days when trainees walk into your office saying their project is not working/going nowhere, and days where they show up to your door with amazing data. Today was definitely the latter scenario!
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ASM @asm.org · 31/08/2026
#MicrobiologyMonday: 150 years ago, Robert Koch identified Bacillus anthracis as the cause of anthrax. However, the first mention of the word "anthrax" to describe the disease appeared much earlier—around 400 BCE. Learn more in #MMBRJournal: asm.social/349
Observations of the B. anthracis capsule by John M’Fadyean. Figure from reference 127. Original legend: “Blood from the tail of a cow dead of anthrax. The greenish-blue bodies are the nuclei of leucocytes; the anthrax bacilli are stained dark blue, and between them is seen the reddish-purple or violet material.”
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 30/08/2026
Pls share: We have a new position for an Assistant Professor of Evolutionary Biology at UNLV. tinyurl.com/4uhpav4j
tinyurl.com
Assistant Professor in Evolutionary Biology, School of Life Sciences [R0153361]
The University of Nevada, Las Vegas (UNLV) appreciates your interest in employment. We ask that you keep in mind the following when completing your application: Once you start the application process ...
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Reposted by Fabrice Jean-Pierre
Lauren Palmer @laurenpalmer.bsky.social · 28/08/2026
Our new paper shows AstR is required to activate ornithine catabolism for A. baumannii to compete with the microbiota in the gut reservoir Led by fantastic first authors John Geary and Xiaomei Ren! 🥳
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 27/08/2026
New in JB: Ntamubano, Parker & Kozik review the current state of Prevotella taxonomy and argue for the the need for more mechanistic studies to understand the role of this microbe in the oral, respiratory & vaginal tracts. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 25/08/2026
New in JB: Karin Sauer and colleagues update us on all the great science at the 10th American Society for Microbiology Conference on Biofilms. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 21/08/2026
Very cool resource out there! #microsky journals.asm.org/doi/10.1128/...
journals.asm.org
The iModulon framework: how x-AI reveals microbial regulatory logic | mSystems
A transcriptome can be regarded as the sum of all regulatory activities under the investigated condition. It enables us to reveal how regulatory systems and biological functions are organized and modu...
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Reposted by Fabrice Jean-Pierre
Ferric Fang, MD @fangferric.bsky.social · 20/08/2026
Prior to COVID, Raoult was one of the most cited and honored life scientists in the world. The COVID-hydroxychloroquine fiasco exposed his glaring ethical and scientific deficiencies, but what took so long? There needs to be a reckoning of the value system which elevated him to the scientific elite.
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Brian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 19/08/2026
Midwest Microbial Pathogenesis Conference Sepember 25-27, 2026 Minneapolis, MN #MicroSky 🦠🧫🧪🧬
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Jehannine (J9) Austin @j9austin.bsky.social · 12/08/2026
As head of the @ubcmedicine.bsky.social Dept of Medical Genetics, I am delighted to share that in collaboration with @bcchresearch.bsky.social we are recruiting a tenure track Assistant Professor clinician scientist: ubc.wd10.myworkdayjobs.com/ubcfacultyjo... There's 0.4FTE clinical attached!
ubc.wd10.myworkdayjobs.com
Assistant Professor (Tenure Track)
Academic Job Category Faculty Bargaining Job Title Assistant Professor (Tenure Track) Department Department of Medical Genetics | Faculty of Medicine | Provost and VP Academic (Jehannine Austin) Posti...
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Mark O. Martin @markowenmartin.bsky.social · 11/08/2026
It's Tuesday, so it is time for a new biweekly episode of #MattersMicrobial! This time, Dr. Michael DL Johnson joins the #QualityQuorum to chat about his "Trojan Horse" strategies to battle superbugs! Please spread the #GoodMicrobialWord? youtu.be/M-FEMi7M-bU?...
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 11/08/2026
New preprint from my lab with @jpcote.bsky.social! In this short report, we present new data suggesting that cystic fibrosis highly effective modulator therapy (such as Trikafta) can impact the capacity of P. aeruginosa to form high biofilm-forming communities. Check it out! #microsky
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 11/08/2026
Dr. Schweizer’s papers on P. aeruginosa genetic tools are probably among the ones that I have cited the most in my papers. Sad to hear that he passed away. #microsky asm.org/obituaries/i...
asm.org
In Memoriam: Schweizer, Herbert Paul
Herbert Paul Schweizer, a leader in bacterial genetics, antimicrobial resistance and infectious disease research, died July 6, 2026, after an exceptional scientific career spanning over 4 decades.
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 10/08/2026
Pls share: Three open posions in Bacteriology at Wisconsin: bact.wisc.edu/bacteriology...
bact.wisc.edu
Bacteriology is Hiring!
Bioeconomy Assistant Professor The Department of Bacteriology is seeking applicants at the Assistant Professor level to launch a research program in the New Bioeconomy. Applicants may be interested in...
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 10/08/2026
New in JB: Authors: Meyer, Bergkessel and DePas link antibiotic resistance the formation of biofilms by Mycobacterium smegmatis. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 10/08/2026
Interesting review!! #microsky
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 04/08/2026
Excited and nervous about this talk!!
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Julia Willett @jlewillett.bsky.social · 04/08/2026
I'm excited to be co-organizing the 2026 Midwest Microbial Pathogenesis Conference, which will take place Sept 25-27 on the UMN campus in Minneapolis! Poster abstracts due Aug 7! Submit yours & register here ➡️ mmpc2026.umn.edu
mmpc2026.umn.edu
Registration | Midwest Microbial Pathogenesis Conference 2026
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 04/08/2026
New collab paper! Lily Charpentier (a Ph.D. grad student in the Stanton lab at Dartmouth) used an in vitro polymicrobial model that we developed a few years ago to explore how polymicrobial bacterial EVs can modulate CF host responses. #microsky isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
isevjournals.onlinelibrary.wiley.com
Polymicrobial Extracellular Vesicles Reduce the Innate Immune Response of Human Cystic Fibrosis Bronchial Epithelial Cells
Chronic antibiotic-resistant cystic fibrosis (CF) lung infections are the leading cause of death in adults with CF. Despite advances in highly effective modulator therapies, microbial communities per...
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 31/07/2026
Pls share. Assistant Professor of Biological Sciences - Genetics/Genomics at Smith College. apply.interfolio.com/190342
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 31/07/2026
JB Editor's Choice: Lallement, Ploy et al. show a role for DNA damage in impacting when insertion sequences "jump". journals.asm.org/doi/10.1128/... @asm.org @microsky.bsky.social #JBacteriol
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 31/07/2026
Pls share: GRINNELL COLLEGE – BIOLOGY DEPARTMENT, TENURE-TRACK POSITION. Research and teaching interests might include but are not limited to organismal biology and ecology - apply by October 2, 2026. Please visit our application website at jobs.grinnell.edu
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 31/07/2026
My last post about the microbial diversity course talked about time in regards to Earth's history. Here is time relevant to the MD course! (Calculations based on 4 of 6 weeks, and 20 students). @mblscience.bsky.social
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Teresa O'Meara @teresaomeara.bsky.social · 29/07/2026
Bacteriology-Focused Assistant Professor Position in Microbiology and Immunology at the University of Michigan Application deadline: August 15, 2026 Come be my colleague!
Bacteriology-Focused Assistant Professor Position in Microbiology and Immunology at the University of Michigan

Application deadline: August 15, 2026

Applicants are requested to send
1) A cover letter (up to 1 page)
2) A CV
3) A description of research interests and goals (up to 2 pages)
4) A description of teaching experience and philosophy (up to 1 page)
5) Contact information including email to solicit 3 letters of recommendation.
Application materials should be combined into one PDF and addressed to the department chair, Dr. Bethany Moore, and sent via email to Sheryl Smith - sherylhs@umich.edu
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Freya Harrison @friendlymicrobe.bsky.social · 28/07/2026
I enjoyed this paper: in a dental #biofilm model, Candida albicans enhances Strep. mutans growth & extracellular matrix production. This is partly because Candida binds & concentrates glucan-producing enzymes secreted by Strep, which remain active. #MicroSky journals.asm.org/doi/10.1128/...
journals.asm.org
Symbiotic Relationship between Streptococcus mutans and Candida albicans Synergizes Virulence of Plaque Biofilms In Vivo | Infection and Immunity
ABSTRACT Streptococcus mutans is often cited as the main bacterial pathogen in dental caries, particularly in early-childhood caries (ECC). S. mutans may not act alone; Candida albicans cells are freq...
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 27/07/2026
JB Editor's Pick: Roberts, Sandkvist et al. examine the role of the GlyGly-CTERM domain in the section/membrane association of T2SS-secreted proteins. journals.asm.org/doi/10.1128/... @asm.org #JBacteriol @microsky.bsky.social
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 26/07/2026
What a finale. Bravo MVDP! #TourdeFrance
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 24/07/2026
The newest issue of JB is out! The cover image features a swimming assay with E. coli. Is there an assay that is more common in modern microbiology?? journals.asm.org/toc/jb/208/7 @asm.org #JBacteriol #MicroSky
journals.asm.org
JB Table of Contents Volume 208, Issue 7
Journal of Bacteriology: Table of Contents Volume 208, Issue 7
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