Thea Jacobs @theajacobs.bsky.social · 01/10/2026A patient has been successfully treated with his own CRISPR-modified stem cells and does not rely on regular blood transfusions anymore. This is so cool! 010
Reposted by Thea JacobsFocalPlane @focalplane.bsky.social · 10/09/2026🔬🔦Our latest Imaging spotlight highlights FOCUS-3D, a tool for segmenting cells from 3D fluorescence images from Qinghua Zhang, @mads100tist.bsky.social, @gqyu.bsky.social & team. They tell us what’s different about FOCUS-3D and what makes it so useful and usable for biologists.focalplane.biologists.comImaging spotlight: FOCUS-3D - FocalPlaneImaging spotlight: FOCUS-3D - News 02911
Thea Jacobs @theajacobs.bsky.social · 14/08/2026Things that sound weird if you are not a scientist: Look I found @maikbischoff.bsky.social ‘s testis (or the muscles that surround them)! 061
Reposted by Thea JacobsFocalPlane @focalplane.bsky.social · 12/08/2026Last few days to apply for a JCS-FocalPlane Training Grant! You can apply for a grant to attend a microscopy/bioimage analysis training course taking place up to 6 months after the deadline. These grants are open to ECRs in cell biology. 🗓️14 August 2026 www.biologists.com/grants/jcs-f... 086
Thea Jacobs @theajacobs.bsky.social · 07/08/2026Happy #FluorescenceFriday ! I have cuticula-shedding office company at the moment, so I took the opportunity to take some cool autofluorescent images of Flossis cuticula! (Plus an image of Flossi herself!) 0276
Reposted by Thea JacobsYichen Luo 骆奕辰 @camellyc.bsky.social · 03/08/20261/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6... 411943
Reposted by Thea JacobsBabli Adhikary @babliadhikary.bsky.social · 20/07/2026Thrilled to share my first publication from my PhD is now out in Journal of Cell Biology!!!! 😇 💖 Have you ever wondered how multicellular vertices are maintained and remodeled in an epithelia? 💭 Here, we investigate the role of junctional kinase PAK4 in vertex maintenance and remodeling! 1176
Reposted by Thea JacobsDiana Khoromskaia @dianakhorom.bsky.social · 13/07/2026Two days left to apply for a PhD position in our group, see below! 067
Reposted by Thea JacobsJosh Currie @joshcurrie.bsky.social · 13/07/2026I love these funky basal epithelial cells in axolotl. Looks just like plant pavement cells 06411
Reposted by Thea JacobsStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 12/06/2026🌈 At a time when progress can't be taken for granted, I 'm especially proud to share this @natcellbio.nature.com Q&A piece. I had the pleasure to discuss with @gunawanlab.bsky.social about his inspiring journey as an LGBTQIA+ immigrant. #PrideInSTEM 👉 rdcu.be/fnXQ6 www.nature.com/articles/s41...nature.comA scientist can come from anywhere - Nature Cell BiologyThis June, we celebrate Pride by discussing with Felix Gunawan, assistant professor at the University of Toronto and co-affiliate group leader at the University of Münster, about his personal and acad... 06421
Reposted by Thea JacobsSociety for Developmental Biology @socdevbio.bsky.social · 22/05/2026✨ Serving egg-cellent organization and fluorescent elegance 🥚 Partial Drosophila 🪰 ovariole with WGA staining of nuclear envelopes 🔬 📸 Image by Michelle Giedt #FluorescenceFriday 🐣 2279
Reposted by Thea JacobsLaura Rustarazo-Calvo @laura-rustarazo.bsky.social · 19/02/2026Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....doi.orgTissue phase transitions in development: more than just mechanicsSummary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall... 27526
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 18/02/2026Registration is now open! Secure your spot for the @sfb1348.bsky.social International Meeting “Mechanochemical signals at cellular interfaces” @uni-muenster.de from May 27–29, 2026! More informationen and registration: www.uni-muenster.de/SFB1348/en/m... 073
Thea Jacobs @theajacobs.bsky.social · 18/02/2026New work from our group now online @biorxiv-devbio.bsky.social 🤩 093
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 14/01/2026Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026. Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w @uni-muenster.de 01714
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 05/01/2026Looking forward to an exciting @sfb1348.bsky.social seminar with Lucia Baldauf @ucl.ac.uk on January 8, 2026. She will speak about "Illuminating Forces in Living Tissues". More info: www.uni-muenster.de/SFB1348/en/i... Everyone's welcome! 084
Reposted by Thea Jacobsmyosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 02/01/2026www.science.org/doi/10.1126/...science.orgActomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organizationIn vitro reconstitution shows how mechanosensitive adherens junction proteins link actomyosin contractility to actin assembly. 2259
Thea Jacobs @theajacobs.bsky.social · 15/12/2025Interested in working in an exciting project on morphogenesis, in a great environment for imaging? 🪰🔬 020
Reposted by Thea JacobsMaik Bischoff @maikbischoff.bsky.social · 25/11/2025Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰 We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila. I’ll soon hire my first #PhD student — feel free to reach out! #juniorPI #Science #devbio 2510522
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 21/11/2025Dynamic cellular interfaces reloaded!🎉 Happy and excited to receive extended funding @sfb1348.bsky.social @uni-muenster.de @mpi-muenster.bsky.social and to push our collaborative science forward in the next 4 years! Big thanks @dfg.de, reviewers, and everyone else involved for the continued support! 54511
Reposted by Thea JacobsStefan Luschnig @luschnig.bsky.social · 12/11/2025Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp 02734
Reposted by Thea JacobsSara Wickstrom @sarawickstrom.bsky.social · 06/11/2025Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support! 2412714
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 27/10/2025Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m... 04832
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 16/09/2025Approximately 14,000 visitors attended the “Lange Nacht der Universitätsmedizin Münster”, which marked the highlight of the anniversary year celebrating 100 years of the Faculty of Medicine and the University Hospital. www.uni-muenster.de/Cells-in-Mot... @sfb1348.bsky.social @uni-muenster.deuni-muenster.dePhoto gallery: “Lange Nacht der Universitätsmedizin” – Impressions from the Multiscale Imaging CentreOn September 12, 2025, the University and University Hospital Münster opened their doors to the public during the “Lange Nacht der Universitätsmedizin”. At the Multiscale Imaging Centre, many visitors... 032
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 09/09/2025Besuchen Sie uns zur „Langen Nacht der Unimedizin Münster“ am 12. September 2025! Zahlreiche Forschungsgruppen aus der Zell-Dynamik- und Imaging-Community der @uni-muenster.de und @sfb1348.bsky.social öffnen ihre Labore für die Öffentlichkeit! lange-nacht-muenster.delange-nacht-muenster.deLange Nacht der Universitätsmedizin Münster - Lange Nacht - 100 Jahre Universitätsmedizin MünsterÜber 12.000 Menschen aus 100 Ländern, 150 Berufe, mehr als 30 Ausbildungsgänge – willkommen in der lebendigen Welt der Universitätsmedizin. Willkommen zur Entdecken Sie die Universitätsmedizin Münster... 0117
Reposted by Thea JacobsKatja Röper @katjaroeper.bsky.social · 27/08/2025Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/... 16324
Reposted by Thea JacobsEmily Kolenbrander Ho @emkolen.bsky.social · 22/07/2025pYtags - our in vivo biosensors for receptor tyrosine kinases - in all their beauty on the cover of Cell Reports! Read more here: www.cell.com/cell-reports... 59120
Reposted by Thea JacobsJuan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 15/07/2025🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social 25320
Reposted by Thea JacobsUniversität Münster @uni-muenster.de · 11/07/2025Using a simple model – #FruitFly eggs – biologist @theajacobs.bsky.social is investigating how cells build connections, and thus form tissues that only allow certain substances or cells to pass through. Here, she provides insight into her day-to-day research. @sfb1348.bsky.social uni.ms/d3ry0uni.msHow does the yolk get into the egg? Studies on the fruit fly | Thea JacobsCells build connections in organisms, and thus, form tissues that only allow certain substances or cells to pass through. In her doctoral thesis, biologist Thea Jacobs has carried out investigations o... 0106
Reposted by Thea JacobsUniversität Münster @uni-muenster.de · 11/07/2025Neurobiologist Bente Winkler @b-wink.bsky.social investigates how the brain reacts to #neuroinflammation. For this, she is using genetically modified #Drosophila flies that enable an artificial activation of the immune system. Read more: uni.ms/48q7kuni.msInflammation in the brain: My research on the fruit fly | Bente WinklerNeurobiologist Dr Bente Winkler is investigating how fruit fly brains react to inflammation. To do this, she is using genetically modified fruit flies in which a reaction of the immune system can be a... 094
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 07/07/2025Exciting @sfb1348.bsky.social with Katja Rust (Philipps-University Marburg) on Thursday. She will speak about "A single-cell analysis of Hh and EGFR-RAS: Independent signaling pathways prevent tumorigenesis". More information: www.uni-muenster.de/SFB1348/en/i... Everyone is welcome! 084
Thea Jacobs @theajacobs.bsky.social · 04/07/2025It’s #FluorescenceFriday again! @maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu... 04110
Reposted by Thea JacobsMackenzie Weygandt Mathis @trackingactions.bsky.social · 24/06/2025🥰 Self-supervised, label-free 3D cell imaging is here Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!). And many thanks to my other awesome co-authors🙏 elifesciences.org/articles/99848actu.epfl.chSelf-supervised, label-free 3D cell imaging is hereEPFL researchers introduce CellSeg3D, a self-supervised tool for 3D cell segmentation in fluorescence microscopy, eliminating the need for manual labeling and enhancing accessibility for various biolo... 110031
Reposted by Thea JacobsSFB 1348 @sfb1348.bsky.social · 29/04/2025Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de We can't wait to see you there! crc1348-conference.ycode.site #DynamicCellularInterfaces #Münster 0189
Reposted by Thea JacobsStefan Luschnig @luschnig.bsky.social · 24/03/2025Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely! Epithelial biology: Holding the corners together: shorturl.at/cMziC @sfb1348.bsky.social @uni-muenster.decell.comEpithelial biology: Holding the corners togetherA new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work res... 1299
Reposted by Thea Jacobsepithelial mechanics fan club @epimechfc.bsky.social · 09/03/2025This dot is a region that intersect multiple cell junctions in an epithelia. These dots act as tiny anchors of cell contacts and they’re critical for epithelial coherence during homeostasis AND development. I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices. 37030
Reposted by Thea JacobsBardin Lab @bardinlab.bsky.social · 07/03/2025Paris Now #StandUpForScience @standupforscience.bsky.social @standupforscifr.bsky.social compliments of sulekh.bsky.social one of our postdocs! 319945
Reposted by Thea JacobsAlushin Lab @alushinlab.bsky.social · 18/02/2025Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6hbit.lyAfadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvatureAfadin strengthens adherens junctions by stabilizing cadherin-catenin complex clusters on curved F-actin. 2157
Reposted by Thea JacobsBeing Liberal ®🗽🏳️🌈 @beingliberal.bsky.social · 02/03/2025#science - in the light of potential enshittification of #PubMed - Ihere's an European alternative to PubMed - www.europepmc.org It's not censored or brought down by would-be-dictators.🧪europepmc.orgEurope PMCHome - Europe PMCEurope PMC is an archive of life sciences journal literature. 722798
Reposted by Thea JacobsStefan Luschnig @luschnig.bsky.social · 17/02/2025Our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social shows how relaxation of tension, rather than active actomyosin-based force, allows opening of cell #vertices to increase #epithelial permeability shorturl.at/Wnb2n @sfb1348.bsky.social @uni-muenster.decell.comRho/Rok-dependent regulation of actomyosin contractility at tricellular junctions restricts epithelial permeability in DrosophilaCell vertices integrate forces in epithelia and play key roles in regulating barrier function. Jacobs et al. show that modulation of actomyosin contractility at cell vertices controls tricellular junc... 15614
Reposted by Thea JacobsVítor Yang @vitoryang.bsky.social · 21/01/2025It's always mesmerizing seeing how these group of cells move. ℹ️Border cells invading through nurse cells ℹ️Drosophila S9 egg chambers 1143
Thea Jacobs @theajacobs.bsky.social · 22/11/2024#fluorescentfriday with a Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta). We use the follicle epithelium as a model to study junction remodelling and barrier formation. Check out our preprint on how Rok regulates paracellular permeability: www.biorxiv.org/content/10.1... 0122
Reposted by Thea JacobsTeun Huijben @teunhuijben.bsky.social · 13/11/20245/ 🐣 With this technology at hand, we build the Virtual Embryo Zoo (virtual-embryo-zoo.sf.czbiohub.org), a showcase of cell-tracking datasets from 6 model organisms, including zebrafish and Drosophila. Explore them interactively, trace lineages, and download tracking data for further analysis! 🐠🐭 1258