Reposted by Diana KhoromskaiaClaire Dessalles @clairedessalles.bsky.social · 23/09/2026NeMo is finally out! 🐟 We present our new method to peel cellular layers and extract their nematics. If you're wondering what a fish has to do with curved nematics, check out the thread and the publication 👀👇🏼 arxiv.org/html/2609.12... 25224
Reposted by Diana KhoromskaiaStefan Luschnig @luschnig.bsky.social · 09/09/2026Interested in combining #Drosophila genetics, advanced imaging, and modeling to study inter-organ transport and epithelial dynamics? Apply now for #PhD position @uni-muenster.de, integrated in @sfb1348.bsky.social Graduate School. Learn more tinyurl.com/5n86bmsf and tinyurl.com/ypx74a5d 01610
Diana Khoromskaia @dianakhorom.bsky.social · 13/07/2026Two days left to apply for a PhD position in our group, see below! 067
Diana Khoromskaia @dianakhorom.bsky.social · 06/07/2026🚨Job Alert: PhD in Theoretical Biophysics 🚨 we are looking for a PhD student to join our group at Uni Münster to work on models of multi-layered active materials @uni-muenster.de More details here: stellen.uni-muenster.de/jobposting/6... Please share and contact me if interested!stellen.uni-muenster.deDoctoral Research Associate (Wissenschaftliche*r Mitarbeiter*in, salary level E 13 TV-L, 67%) 033
Reposted by Diana KhoromskaiaJames Briscoe @jamesbriscoe.bsky.social · 01/07/2026New in @dev-journal.bsky.social: how tissue shape tells cells what to become Using human stem-cell neuruloids, we show how that physical boundaries encode positional information that drives cell fate patterning in a model of trunk formation A thread 🧵 journals.biologists.com/dev/article/...journals.biologists.comBoundary constraints can determine pattern emergenceSummary: A reaction-diffusion mechanism recapitulates pattern emergence in an in vitro model of neuromesodermal progenitors under a variety of boundary and geometrical perturbations. 25216
Reposted by Diana KhoromskaiaBiophysical Journal @biophysj.bsky.social · 09/06/2026#OPENACCESS: Cells don’t just communicate through calcium waves; nematic cell alignment shapes how information propagates. Winterstrain et al. show that nematic defects can desynchronize signaling, with calcium waves traveling fastest when perpendicular to tissue orientation.cell.comNematic cell alignment directs calcium waves in an epithelial monolayerTissues rely on supracellular signals to coordinate their cells over a long range. Two such tissue-scale cues are calcium waves and patterns of cell-cell alignment or nematic order. During wound… 0164
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 03/06/2026This year’s @sfb1348.bsky.social meeting @uni-muenster.de has come to a close. 3 days of inspiring science, stimulating discussions, and valuable exchange made it a truly rewarding event. Many thanks to all participants - we’re already looking forward to the next one! Photos © Michael Kuhlmann 0115
Reposted by Diana KhoromskaiaNature Cell Biology @natcellbio.nature.com · 01/06/2026🍰Read also the Research Briefing: 👉https://rdcu.be/flTlO bit.ly/4wWf0CFbit.lyTissue organization and morphogen gradients dynamically tune one another - Nature Cell BiologyDuring embryogenesis, morphogen signalling is known to pattern tissues as they remodel. Using genetic and optogenetic perturbations, together with theoretical frameworks of phase transitions and bioch... 093
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 27/05/2026in the starting blocks ... Excited to open the meeting today! Mechanochemical Signals at #CellularInterfaces @sfb1348.bsky.social @uni-muenster.de www.uni-muenster.de/SFB1348/en/m... 0114
Reposted by Diana KhoromskaiaCamilla Autorino @cami-autorino.bsky.social · 18/05/2026💫 Our paper is now published at @natcellbio.nature.com! So excited about this work done during my PhD at @embl.org in the group of @nicolettapetridou.bsky.social along with our great collaborators! 🐟🎉 0288
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 13/05/2026The @sfb1348.bsky.social Meeting “Mechanochemical Signals at Cellular Interfaces” is just around the corner! We are excited to welcome an outstanding lineup of international speakers to #Münster for three days of inspiring scientific exchange and discussion. @uni-muenster.de 13113
Reposted by Diana KhoromskaiaNicoletta Petridou @nicolettapetridou.bsky.social · 15/05/2026Glad to see this out in its final form! www.nature.com/articles/s41... What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏nature.comTissue rigidity phase transition shapes morphogen gradients - Nature Cell BiologyAutorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l... 712944
Reposted by Diana KhoromskaiaStefan Luschnig @luschnig.bsky.social · 13/05/2026This is going to be marvellous — looking forward to three inspiring days of exchange and discussion on #cellularinterfaces @sfb1348.bsky.social @uni-muenster.de 0103
Reposted by Diana KhoromskaiaClaire Dessalles @clairedessalles.bsky.social · 22/04/2026All you ever wanted to know about how to analyse the nematic nature of cellular tissues is right here 👀👇🏼! Bonus #1: we did it for many cell types and uncovered unexpected defect behavior 🐌 Bonus #2: for theoreticians looking for parameter values for your simulation🧑🏼💻 tinyurl.com/2s399yen 44418
Reposted by Diana KhoromskaiaPau Guillamat @pauguillamat.bsky.social · 16/04/2026Just published in @science.org 🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials! www.science.org/doi/10.1126/...science.orgScience | AAAS 88433
Reposted by Diana KhoromskaiaBiophysical Journal @biophysj.bsky.social · 08/04/2026New study on topological defects develops a mechanochemical model integrating morphogen concentration and hydrodynamic flow, reproducing experimental collective motility and revealing viscosity, activity, and alignment strength as key factors governing defect-mediated transport.cell.comMechanochemical coupling regulates defect dynamics in active nematicsActive nematics offer a versatile continuum framework for nonequilibrium collective phenomena, such as collective cell migration and tissue morphogenesis. However, the dynamic evolution of active… 043
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 16/03/2026The CiM-IMPRS PhD program in #Münster is offering 16 #PhD positions in Life and Natural Sciences! Perform cutting-edge resesearch in a vibrant international setting and lively city! Apply by May 1st, 2026 - see www.uni-muenster.de/CiM-IMPRS/ap... @uni-muenster.de @mpi-muenster.bsky.social 01112
Reposted by Diana KhoromskaiaBiology-UNIGE @biology-unige.bsky.social · 24/03/2026Congratulations Guillaume #Salbreux and collaborator @aikmi.bsky.social groups for your latest publication in @cellcellpress.bsky.social: Deciphering #mechanical determinants of morphological #evolution @genevunige.bsky.social @sciencesunige.bsky.social #UNIGE 👉 www.cell.com/cell/fulltex...cell.comDeciphering mechanical determinants of morphological evolutionA comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m... 074
Reposted by Diana KhoromskaiaEMBL @embl.org · 23/03/2026A sea anemone looks very different from a coral, despite belonging to the same broad biological group. A new study from EMBL researchers and their colleagues sheds new light on how diversity arises in body shapes in the animal world. www.embl.org/news/science... 0299
Reposted by Diana KhoromskaiaEMBL DB unit @embldbunit.bsky.social · 20/03/2026🔥Exciting new paper from the Ikmi group @embl.org! The authors identified a set of mesoscale mechanical modules that can be used to predict species-specific shapes by combining a comparative analysis of cnidarian larval morphogenesis with active surface theory #morphogenesis #cnidaria 073
Diana Khoromskaia @dianakhorom.bsky.social · 20/03/2026Amazing to see this study finally out! Proud to have contributed to the active surface modelling of cnidaria morphogenesis across species and huge congrats to Richard, Nicolas, and all authors! #morphogenesis #activematter #nematicorder #evolution 1202
Reposted by Diana KhoromskaiaCell - a Cell Press journal @cp-cell.bsky.social · 20/03/2026Now online! Deciphering mechanical determinants of morphological evolutiondlvr.itDeciphering mechanical determinants of morphological evolutionA comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these modules reprograms morphology, revealing how variation in tissue-scale mechanics underlies morphological diversity. 0134
Reposted by Diana KhoromskaiaDevelopment @dev-journal.bsky.social · 20/02/2026Tissue phase transitions in development: more than just mechanics In this Review, @nicolettapetridou.bsky.social, @laura-rustarazo.bsky.social and @karengrace12.bsky.social discuss tissue phase transitions during development: doi.org/10.1242/dev.... 0244
Reposted by Diana KhoromskaiaNicoletta Petridou @nicolettapetridou.bsky.social · 19/02/2026We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔) 0319
Reposted by Diana KhoromskaiaLaura Rustarazo-Calvo @laura-rustarazo.bsky.social · 19/02/2026Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....doi.orgTissue phase transitions in development: more than just mechanicsSummary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall... 27526
Reposted by Diana KhoromskaiaStefan Luschnig @luschnig.bsky.social · 18/02/2026New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila See tinyurl.com/yhbwd9xh @sfb1348.bsky.social 48729
Reposted by Diana KhoromskaiaHenry De Belly @henrydebelly.bsky.social · 13/02/2026My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology! We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior. Come do cool science with me! lnkd.in/gKEXWUGylnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 01410
Reposted by Diana Khoromskaia@physicsoflifeuk @physicsoflifeuk.bsky.social · 10/02/2026Join us today 2-3pm online. Sign up for the Zoom link here: forms.gle/Mt3y7HQXetrb... 021
Reposted by Diana Khoromskaiaepithelial mechanics fan club @epimechfc.bsky.social · 16/01/2026Isasti-Sanchez, J., Münz-Zeise, F., Lancino, M., & Luschnig, S. (2021). Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis. Developmental Cell, #EpithelialMechanics doi.org/10.1016/j.de... 071
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 14/01/2026Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026. Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w @uni-muenster.de 01714
Reposted by Diana KhoromskaiaGuillaume Charras @gcharras.bsky.social · 18/12/2025How does signalling control cortical tension? Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling. More here: www.biorxiv.org/content/10.6... Super work by Pierre Bohec with Guillaume Salbreux and @dianakhorom.bsky.social 05611
Diana Khoromskaia @dianakhorom.bsky.social · 06/01/2026New preprint out! We use optogenetics, AFM, and active surface modelling to link signalling ⚡ → mechanics ⚙️ → cell shape 🔵 081
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 05/01/2026Looking forward to an exciting @sfb1348.bsky.social seminar with Lucia Baldauf @ucl.ac.uk on January 8, 2026. She will speak about "Illuminating Forces in Living Tissues". More info: www.uni-muenster.de/SFB1348/en/i... Everyone's welcome! 084
Reposted by Diana Khoromskaiamyosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 18/12/2025www.biorxiv.org/content/10.6...biorxiv.orgControl of cellular cortical tension and shape by RhoGTPase signallingShape changes are ubiquitous in biology, from cytokinesis at the single cell scale to tissue-scale morphogenesis involving coordinated changes in hundreds of cells. In all cases, morphogenesis is powe... 082
Reposted by Diana KhoromskaiaAgathe Chaigne @agathechaigne.bsky.social · 18/12/2025My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch! 35966
Reposted by Diana KhoromskaiaMaik Bischoff @maikbischoff.bsky.social · 15/12/2025🚨 PhD Position Available 🚨 I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany. www.bischofflab.com/jobs Fully funded ✅ #Cellbio #Morphogenesis #Microscopy #Drosophila #PhD (Details Below) Original Posting: stellen.uni-muenster.de/jobposting/d... 24635
Reposted by Diana KhoromskaiaManuel Thery @manuelthery.bsky.social · 05/12/2025#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January. 19312103
Reposted by Diana KhoromskaiaClaire Dessalles @clairedessalles.bsky.social · 02/12/2025📢Internships on cellular nematics! 🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis. 📧Feel free to DM or email me with any questions. 11415
Reposted by Diana KhoromskaiaMaik Bischoff @maikbischoff.bsky.social · 28/11/20252/2 If you’re into #cellbio, cellular interfaces, #mechanobiology, #membranes, anything related, come to Münster, Germany, May 27–29! www.uni-muenster.de/SFB1348/en/i... Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it. #Science 01711
Reposted by Diana KhoromskaiaErwin Frey @physicsoflifelmu.bsky.social · 27/11/2025🧪 Geometry beats chemistry: we show that self-assembly can be controlled by tuning large-scale geometric parameters rather than molecular binding energies. PNAS: doi.org/10.1073/pnas... Video summary: www.youtube.com/watch?v=6FS3... #SelfAssembly #Biophysics #PhysicsOfLife 510226
Reposted by Diana KhoromskaiaUniversität Münster @uni-muenster.de · 21/11/2025Große Freude! Die @dfg.de richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert den etablierten Verbund @sfb1348.bsky.social. Insgesamt fließen rund 24 Millionen Euro an die Universität Münster.uni-muenster.de24 Millionen Euro für zwei SonderforschungsbereicheDie Deutsche Forschungsgemeinschaft richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert einen etablierten Verbund zu zellulären Grenzflächen. Insgesamt fließe... 1187
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 21/11/2025Dynamic cellular interfaces reloaded!🎉 Happy and excited to receive extended funding @sfb1348.bsky.social @uni-muenster.de @mpi-muenster.bsky.social and to push our collaborative science forward in the next 4 years! Big thanks @dfg.de, reviewers, and everyone else involved for the continued support! 54511
Reposted by Diana KhoromskaiaUniversität Münster @uni-muenster.de · 14/11/2025In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer „Erklärung für die Zukunft“ an die Öffentlichkeit gewandt. Die Physiker warnen eindringlich vor einer nuklearen Aufrüstung. @dpgphysik.bsky.socialuni-muenster.dePhysik-Fachgesellschaften unterzeichnen „Erklärung für die Zukunft“In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer gemeinsamen „Erklärung für die Zukunft“ an die Öf... 075
Reposted by Diana KhoromskaiaPau Guillamat @pauguillamat.bsky.social · 12/11/2025Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps. @pnas.org @ub.edu www.pnas.org/doi/10.1073/... #ActiveMatter #Microfluidics #SoftMatterpnas.orgActive nematic pumps | PNASMicrofluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alte... 23413
Reposted by Diana KhoromskaiaMarco Mauri @marcomauri.bsky.social · 14/11/2025🚨 Soon at 15:30 EU (in 1h), Guillaume Salbreux (Geneva University) will present the talk From active surfaces to evo-devo-mechanobiology at the Population Dynamics Seminars. sites.google.com/view/popdyn/ 122
Reposted by Diana KhoromskaiaStefan Luschnig @luschnig.bsky.social · 12/11/2025Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp 02734
Reposted by Diana KhoromskaiaSara Wickstrom @sarawickstrom.bsky.social · 06/11/2025Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support! 2412714
Reposted by Diana KhoromskaiaSFB 1348 @sfb1348.bsky.social · 27/10/2025Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m... 04832
Reposted by Diana KhoromskaiaEMBL @embl.org · 29/09/2025New research from EMBL scientists is shedding light on how shape transitions help tissue boundaries form during development. The results reveal a new class of adaptive material dynamics & could provide design principles for smart materials that respond to changing environments. 1103