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Diana Khoromskaia

@dianakhorom.bsky.social
252 followers 361 following 12 posts

Theoretical physics of living matter, cell and tissue morphogenesis Juniorprofessor @uni-muenster.de Prev: Postdoc @TheCrick @UCL Physics| PhD @WarwickUni| MSc @UniHeidelberg‬

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Reposted by Diana Khoromskaia
Claire Dessalles @clairedessalles.bsky.social · 23/09/2026
NeMo is finally out! 🐟 We present our new method to peel cellular layers and extract their nematics. If you're wondering what a fish has to do with curved nematics, check out the thread and the publication 👀👇🏼 arxiv.org/html/2609.12...
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Stefan Luschnig @luschnig.bsky.social · 09/09/2026
Interested in combining #Drosophila genetics, advanced imaging, and modeling to study inter-organ transport and epithelial dynamics? Apply now for #PhD position @uni-muenster.de, integrated in @sfb1348.bsky.social Graduate School. Learn more tinyurl.com/5n86bmsf and tinyurl.com/ypx74a5d
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Diana Khoromskaia @dianakhorom.bsky.social · 13/07/2026
Two days left to apply for a PhD position in our group, see below!
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Diana Khoromskaia @dianakhorom.bsky.social · 06/07/2026
🚨Job Alert: PhD in Theoretical Biophysics 🚨 we are looking for a PhD student to join our group at Uni Münster to work on models of multi-layered active materials @uni-muenster.de More details here: stellen.uni-muenster.de/jobposting/6... Please share and contact me if interested!
stellen.uni-muenster.de
Doctoral Research Associate (Wissenschaftliche*r Mitarbeiter*in, salary level E 13 TV-L, 67%)
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James Briscoe @jamesbriscoe.bsky.social · 01/07/2026
New in @dev-journal.bsky.social: how tissue shape tells cells what to become Using human stem-cell neuruloids, we show how that physical boundaries encode positional information that drives cell fate patterning in a model of trunk formation A thread 🧵 journals.biologists.com/dev/article/...
journals.biologists.com
Boundary constraints can determine pattern emergence
Summary: A reaction-diffusion mechanism recapitulates pattern emergence in an in vitro model of neuromesodermal progenitors under a variety of boundary and geometrical perturbations.
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Biophysical Journal @biophysj.bsky.social · 09/06/2026
#OPENACCESS: Cells don’t just communicate through calcium waves; nematic cell alignment shapes how information propagates. Winterstrain et al. show that nematic defects can desynchronize signaling, with calcium waves traveling fastest when perpendicular to tissue orientation.
cell.com
Nematic cell alignment directs calcium waves in an epithelial monolayer
Tissues rely on supracellular signals to coordinate their cells over a long range. Two such tissue-scale cues are calcium waves and patterns of cell-cell alignment or nematic order. During wound…
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SFB 1348 @sfb1348.bsky.social · 03/06/2026
This year’s @sfb1348.bsky.social meeting @uni-muenster.de has come to a close. 3 days of inspiring science, stimulating discussions, and valuable exchange made it a truly rewarding event. Many thanks to all participants - we’re already looking forward to the next one! Photos © Michael Kuhlmann
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Reposted by Diana Khoromskaia
Nature Cell Biology @natcellbio.nature.com · 01/06/2026
🍰Read also the Research Briefing: 👉https://rdcu.be/flTlO bit.ly/4wWf0CF
bit.ly
Tissue organization and morphogen gradients dynamically tune one another - Nature Cell Biology
During embryogenesis, morphogen signalling is known to pattern tissues as they remodel. Using genetic and optogenetic perturbations, together with theoretical frameworks of phase transitions and bioch...
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SFB 1348 @sfb1348.bsky.social · 27/05/2026
in the starting blocks ... Excited to open the meeting today! Mechanochemical Signals at #CellularInterfaces @sfb1348.bsky.social @uni-muenster.de www.uni-muenster.de/SFB1348/en/m...
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Camilla Autorino @cami-autorino.bsky.social · 18/05/2026
💫 Our paper is now published at @natcellbio.nature.com! So excited about this work done during my PhD at @embl.org in the group of @nicolettapetridou.bsky.social along with our great collaborators! 🐟🎉
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SFB 1348 @sfb1348.bsky.social · 13/05/2026
The @sfb1348.bsky.social Meeting “Mechanochemical Signals at Cellular Interfaces” is just around the corner! We are excited to welcome an outstanding lineup of international speakers to #Münster for three days of inspiring scientific exchange and discussion. @uni-muenster.de
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Nicoletta Petridou @nicolettapetridou.bsky.social · 15/05/2026
Glad to see this out in its final form! www.nature.com/articles/s41... What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏
nature.com
Tissue rigidity phase transition shapes morphogen gradients - Nature Cell Biology
Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...
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Stefan Luschnig @luschnig.bsky.social · 13/05/2026
This is going to be marvellous — looking forward to three inspiring days of exchange and discussion on #cellularinterfaces @sfb1348.bsky.social @uni-muenster.de
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Claire Dessalles @clairedessalles.bsky.social · 22/04/2026
All you ever wanted to know about how to analyse the nematic nature of cellular tissues is right here 👀👇🏼! Bonus #1: we did it for many cell types and uncovered unexpected defect behavior 🐌 Bonus #2: for theoreticians looking for parameter values for your simulation🧑🏼‍💻 tinyurl.com/2s399yen
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Pau Guillamat @pauguillamat.bsky.social · 16/04/2026
Just published in @science.org 🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials! 🫆 www.science.org/doi/10.1126/...
science.org
Science | AAAS
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Biophysical Journal @biophysj.bsky.social · 08/04/2026
New study on topological defects develops a mechanochemical model integrating morphogen concentration and hydrodynamic flow, reproducing experimental collective motility and revealing viscosity, activity, and alignment strength as key factors governing defect-mediated transport.
cell.com
Mechanochemical coupling regulates defect dynamics in active nematics
Active nematics offer a versatile continuum framework for nonequilibrium collective phenomena, such as collective cell migration and tissue morphogenesis. However, the dynamic evolution of active…
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SFB 1348 @sfb1348.bsky.social · 16/03/2026
The CiM-IMPRS PhD program in #Münster is offering 16 #PhD positions in Life and Natural Sciences! Perform cutting-edge resesearch in a vibrant international setting and lively city! Apply by May 1st, 2026 - see www.uni-muenster.de/CiM-IMPRS/ap... @uni-muenster.de @mpi-muenster.bsky.social
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Biology-UNIGE @biology-unige.bsky.social · 24/03/2026
Congratulations Guillaume #Salbreux and collaborator @aikmi.bsky.social groups for your latest publication in @cellcellpress.bsky.social: Deciphering #mechanical determinants of morphological #evolution @genevunige.bsky.social @sciencesunige.bsky.social #UNIGE 👉 www.cell.com/cell/fulltex...
cell.com
Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m...
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EMBL @embl.org · 23/03/2026
A sea anemone looks very different from a coral, despite belonging to the same broad biological group. A new study from EMBL researchers and their colleagues sheds new light on how diversity arises in body shapes in the animal world. www.embl.org/news/science...
Pictured are cross sections of larvae from Nematotstella (left) and Aiptasia (right), with the sliders underneath representing the mechanical modules which combine to give rise to an organism's mechanotype. Credit: Daniela Velasco/EMBL
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EMBL DB unit @embldbunit.bsky.social · 20/03/2026
🔥Exciting new paper from the Ikmi group @embl.org! The authors identified a set of mesoscale mechanical modules that can be used to predict species-specific shapes by combining a comparative analysis of cnidarian larval morphogenesis with active surface theory #morphogenesis #cnidaria
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Diana Khoromskaia @dianakhorom.bsky.social · 20/03/2026
Amazing to see this study finally out! Proud to have contributed to the active surface modelling of cnidaria morphogenesis across species and huge congrats to Richard, Nicolas, and all authors! #morphogenesis #activematter #nematicorder #evolution
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Cell - a Cell Press journal @cp-cell.bsky.social · 20/03/2026
Now online! Deciphering mechanical determinants of morphological evolution
dlvr.it
Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these modules reprograms morphology, revealing how variation in tissue-scale mechanics underlies morphological diversity.
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Development @dev-journal.bsky.social · 20/02/2026
Tissue phase transitions in development: more than just mechanics In this Review, @nicolettapetridou.bsky.social, @laura-rustarazo.bsky.social and @karengrace12.bsky.social discuss tissue phase transitions during development: doi.org/10.1242/dev....
•	Figure 1 of the article: Fig. 1. Phase diagram of tissue material phase transitions and examples. (A) Schematic diagram showing how continuous changes in microscopic dynamics (control parameter) lead to abrupt, drastic, and non-linear shifts in macroscopic properties that define the material response (order parameter). (Aa-Ab) Exemplary phase transitions as traditionally described in non-living matter, e.g. for water (Aa), as well as in living matter, e.g. for embryonic tissues (Ab). Yellow areas indicate fluid-like tissues and regimes. Blue areas indicate solid-like tissues and regimes. Magenta dashed line depicts the critical point. Orange line marks particle and cell trajectories.
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Nicoletta Petridou @nicolettapetridou.bsky.social · 19/02/2026
We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)
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Laura Rustarazo-Calvo @laura-rustarazo.bsky.social · 19/02/2026
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....
doi.org
Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
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Stefan Luschnig @luschnig.bsky.social · 18/02/2026
New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila See tinyurl.com/yhbwd9xh @sfb1348.bsky.social
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Henry De Belly @henrydebelly.bsky.social · 13/02/2026
My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology! We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior. Come do cool science with me! lnkd.in/gKEXWUGy
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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@physicsoflifeuk @physicsoflifeuk.bsky.social · 10/02/2026
Join us today 2-3pm online. Sign up for the Zoom link here: forms.gle/Mt3y7HQXetrb...
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epithelial mechanics fan club @epimechfc.bsky.social · 16/01/2026
Isasti-Sanchez, J., Münz-Zeise, F., Lancino, M., & Luschnig, S. (2021). Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis. Developmental Cell, #EpithelialMechanics doi.org/10.1016/j.de...
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SFB 1348 @sfb1348.bsky.social · 14/01/2026
Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026. Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w @uni-muenster.de
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Guillaume Charras @gcharras.bsky.social · 18/12/2025
How does signalling control cortical tension? Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling. More here: www.biorxiv.org/content/10.6... Super work by Pierre Bohec with Guillaume Salbreux and @dianakhorom.bsky.social
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Diana Khoromskaia @dianakhorom.bsky.social · 06/01/2026
New preprint out! We use optogenetics, AFM, and active surface modelling to link signalling ⚡ → mechanics ⚙️ → cell shape 🔵
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SFB 1348 @sfb1348.bsky.social · 05/01/2026
Looking forward to an exciting @sfb1348.bsky.social seminar with Lucia Baldauf @ucl.ac.uk on January 8, 2026. She will speak about "Illuminating Forces in Living Tissues". More info: www.uni-muenster.de/SFB1348/en/i... Everyone's welcome!
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myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 18/12/2025
www.biorxiv.org/content/10.6...
biorxiv.org
Control of cellular cortical tension and shape by RhoGTPase signalling
Shape changes are ubiquitous in biology, from cytokinesis at the single cell scale to tissue-scale morphogenesis involving coordinated changes in hundreds of cells. In all cases, morphogenesis is powe...
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Agathe Chaigne @agathechaigne.bsky.social · 18/12/2025
My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
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Maik Bischoff @maikbischoff.bsky.social · 15/12/2025
🚨 PhD Position Available 🚨 I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany. www.bischofflab.com/jobs Fully funded ✅ #Cellbio #Morphogenesis #Microscopy #Drosophila #PhD (Details Below) Original Posting: stellen.uni-muenster.de/jobposting/d...
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Manuel Thery @manuelthery.bsky.social · 05/12/2025
#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.
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Claire Dessalles @clairedessalles.bsky.social · 02/12/2025
📢Internships on cellular nematics! 🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis. 📧Feel free to DM or email me with any questions.
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Claire Dessalles @clairedessalles.bsky.social · 02/12/2025
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Maik Bischoff @maikbischoff.bsky.social · 28/11/2025
2/2 If you’re into #cellbio, cellular interfaces, #mechanobiology, #membranes, anything related, come to Münster, Germany, May 27–29! www.uni-muenster.de/SFB1348/en/i... Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it. #Science
The historc city center of Münster, famous for the Peace of Westphalia!
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Erwin Frey @physicsoflifelmu.bsky.social · 27/11/2025
🧪 Geometry beats chemistry: we show that self-assembly can be controlled by tuning large-scale geometric parameters rather than molecular binding energies. PNAS: doi.org/10.1073/pnas... Video summary: www.youtube.com/watch?v=6FS3... #SelfAssembly #Biophysics #PhysicsOfLife
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Universität Münster @uni-muenster.de · 21/11/2025
Große Freude! Die @dfg.de richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert den etablierten Verbund @sfb1348.bsky.social. Insgesamt fließen rund 24 Millionen Euro an die Universität Münster.
uni-muenster.de
24 Millionen Euro für zwei Sonderforschungsbereiche
Die Deutsche Forschungsgemeinschaft richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert einen etablierten Verbund zu zellulären Grenzflächen. Insgesamt fließe...
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SFB 1348 @sfb1348.bsky.social · 21/11/2025
Dynamic cellular interfaces reloaded!🎉 Happy and excited to receive extended funding @sfb1348.bsky.social @uni-muenster.de @mpi-muenster.bsky.social and to push our collaborative science forward in the next 4 years! Big thanks @dfg.de, reviewers, and everyone else involved for the continued support!
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Universität Münster @uni-muenster.de · 14/11/2025
In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer „Erklärung für die Zukunft“ an die Öffentlichkeit gewandt. Die Physiker warnen eindringlich vor einer nuklearen Aufrüstung. @dpgphysik.bsky.social
uni-muenster.de
Physik-Fachgesellschaften unterzeichnen „Erklärung für die Zukunft“
In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer gemeinsamen „Erklärung für die Zukunft“ an die Öf...
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Pau Guillamat @pauguillamat.bsky.social · 12/11/2025
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps. @pnas.org @ub.edu www.pnas.org/doi/10.1073/... #ActiveMatter #Microfluidics #SoftMatter
pnas.org
Active nematic pumps | PNAS
Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alte...
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Marco Mauri @marcomauri.bsky.social · 14/11/2025
🚨 Soon at 15:30 EU (in 1h), Guillaume Salbreux (Geneva University) will present the talk From active surfaces to evo-devo-mechanobiology at the Population Dynamics Seminars. sites.google.com/view/popdyn/
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Stefan Luschnig @luschnig.bsky.social · 12/11/2025
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
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Sara Wickstrom @sarawickstrom.bsky.social · 06/11/2025
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
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SFB 1348 @sfb1348.bsky.social · 27/10/2025
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
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EMBL @embl.org · 29/09/2025
New research from EMBL scientists is shedding light on how shape transitions help tissue boundaries form during development. The results reveal a new class of adaptive material dynamics & could provide design principles for smart materials that respond to changing environments.
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