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Thea Jacobs

@theajacobs.bsky.social
267 followers 443 following 8 posts

Postdoc in the Luschnig lab. Flyologist 🪰 here to share my excitement about actomyosin. Check out how contractility controls paracellular permeability here: shorturl.at/Wnb2n

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Reposted by Thea Jacobs
FocalPlane @focalplane.bsky.social · 10/09/2026
🔬🔦Our latest Imaging spotlight highlights FOCUS-3D, a tool for segmenting cells from 3D fluorescence images from Qinghua Zhang, @mads100tist.bsky.social, @gqyu.bsky.social & team. They tell us what’s different about FOCUS-3D and what makes it so useful and usable for biologists.
focalplane.biologists.com
Imaging spotlight: FOCUS-3D - FocalPlane
Imaging spotlight: FOCUS-3D - News
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Thea Jacobs @theajacobs.bsky.social · 14/08/2026
Things that sound weird if you are not a scientist: Look I found @maikbischoff.bsky.social ‘s testis (or the muscles that surround them)!
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Reposted by Thea Jacobs
FocalPlane @focalplane.bsky.social · 12/08/2026
Last few days to apply for a JCS-FocalPlane Training Grant! You can apply for a grant to attend a microscopy/bioimage analysis training course taking place up to 6 months after the deadline. These grants are open to ECRs in cell biology. 🗓️14 August 2026 www.biologists.com/grants/jcs-f...
Microscopy Training Grants
Supporting microscopy training for early-career researchers in cell biology
Apply for a grant of up to £1,000
Cartoon of a person looking down a microscope, which is next to a computer
Journal of Cell Science logo and FocalPlane logo
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Thea Jacobs @theajacobs.bsky.social · 07/08/2026
Happy #FluorescenceFriday ! I have cuticula-shedding office company at the moment, so I took the opportunity to take some cool autofluorescent images of Flossis cuticula! (Plus an image of Flossi herself!)
Color-coded Z-projection of Triops cuticula, mouth region.Color-coded Z-projection of Triops cuticula, some appendage on the thorax.Color-coded Z-projection of Triops cuticula, some appendage on the abdomen.Flossi (a Tripos) in her aquarium.
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Yichen Luo 骆奕辰 @camellyc.bsky.social · 03/08/2026
1/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6...
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Babli Adhikary @babliadhikary.bsky.social · 20/07/2026
Thrilled to share my first publication from my PhD is now out in Journal of Cell Biology!!!! 😇 💖 Have you ever wondered how multicellular vertices are maintained and remodeled in an epithelia? 💭 Here, we investigate the role of junctional kinase PAK4 in vertex maintenance and remodeling!
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Diana Khoromskaia @dianakhorom.bsky.social · 13/07/2026
Two days left to apply for a PhD position in our group, see below!
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Josh Currie @joshcurrie.bsky.social · 13/07/2026
I love these funky basal epithelial cells in axolotl. Looks just like plant pavement cells
basal squamous epithelial cells in the axolotl expressing a membrane-localized fluorescent protein
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Thea Jacobs @theajacobs.bsky.social · 03/07/2026
Great scientist, even better person 💕
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Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 12/06/2026
🌈 At a time when progress can't be taken for granted, I 'm especially proud to share this @natcellbio.nature.com Q&A piece. I had the pleasure to discuss with @gunawanlab.bsky.social about his inspiring journey as an LGBTQIA+ immigrant. #PrideInSTEM 👉 rdcu.be/fnXQ6 www.nature.com/articles/s41...
nature.com
A scientist can come from anywhere - Nature Cell Biology
This June, we celebrate Pride by discussing with Felix Gunawan, assistant professor at the University of Toronto and co-affiliate group leader at the University of Münster, about his personal and acad...
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Society for Developmental Biology @socdevbio.bsky.social · 22/05/2026
✨ Serving egg-cellent organization and fluorescent elegance 🥚 Partial Drosophila 🪰 ovariole with WGA staining of nuclear envelopes 🔬 📸 Image by Michelle Giedt #FluorescenceFriday 🐣
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Laura Rustarazo-Calvo @laura-rustarazo.bsky.social · 19/02/2026
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....
doi.org
Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
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Reposted by Thea Jacobs
SFB 1348 @sfb1348.bsky.social · 18/02/2026
Registration is now open! Secure your spot for the @sfb1348.bsky.social International Meeting “Mechanochemical signals at cellular interfaces” @uni-muenster.de from May 27–29, 2026! More informationen and registration: www.uni-muenster.de/SFB1348/en/m...
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Thea Jacobs @theajacobs.bsky.social · 18/02/2026
New work from our group now online @biorxiv-devbio.bsky.social 🤩
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SFB 1348 @sfb1348.bsky.social · 14/01/2026
Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026. Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w @uni-muenster.de
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SFB 1348 @sfb1348.bsky.social · 05/01/2026
Looking forward to an exciting @sfb1348.bsky.social seminar with Lucia Baldauf @ucl.ac.uk on January 8, 2026. She will speak about "Illuminating Forces in Living Tissues". More info: www.uni-muenster.de/SFB1348/en/i... Everyone's welcome!
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Reposted by Thea Jacobs
myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 02/01/2026
www.science.org/doi/10.1126/...
science.org
Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization
In vitro reconstitution shows how mechanosensitive adherens junction proteins link actomyosin contractility to actin assembly.
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Thea Jacobs @theajacobs.bsky.social · 15/12/2025
Interested in working in an exciting project on morphogenesis, in a great environment for imaging? 🪰🔬
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Maik Bischoff @maikbischoff.bsky.social · 25/11/2025
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰 We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila. I’ll soon hire my first #PhD student — feel free to reach out! #juniorPI #Science #devbio
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SFB 1348 @sfb1348.bsky.social · 21/11/2025
Dynamic cellular interfaces reloaded!🎉 Happy and excited to receive extended funding @sfb1348.bsky.social @uni-muenster.de @mpi-muenster.bsky.social and to push our collaborative science forward in the next 4 years! Big thanks @dfg.de, reviewers, and everyone else involved for the continued support!
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Stefan Luschnig @luschnig.bsky.social · 12/11/2025
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
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Sara Wickstrom @sarawickstrom.bsky.social · 06/11/2025
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
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SFB 1348 @sfb1348.bsky.social · 27/10/2025
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
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SFB 1348 @sfb1348.bsky.social · 16/09/2025
Approximately 14,000 visitors attended the “Lange Nacht der Universitätsmedizin Münster”, which marked the highlight of the anniversary year celebrating 100 years of the Faculty of Medicine and the University Hospital. www.uni-muenster.de/Cells-in-Mot... @sfb1348.bsky.social @uni-muenster.de
uni-muenster.de
Photo gallery: “Lange Nacht der Universitätsmedizin” – Impressions from the Multiscale Imaging Centre
On September 12, 2025, the University and University Hospital Münster opened their doors to the public during the “Lange Nacht der Universitätsmedizin”. At the Multiscale Imaging Centre, many visitors...
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Reposted by Thea Jacobs
SFB 1348 @sfb1348.bsky.social · 09/09/2025
Besuchen Sie uns zur „Langen Nacht der Unimedizin Münster“ am 12. September 2025! Zahlreiche Forschungsgruppen aus der Zell-Dynamik- und Imaging-Community der @uni-muenster.de und @sfb1348.bsky.social öffnen ihre Labore für die Öffentlichkeit! lange-nacht-muenster.de
lange-nacht-muenster.de
Lange Nacht der Universitätsmedizin Münster - Lange Nacht - 100 Jahre Universitätsmedizin Münster
Über 12.000 Menschen aus 100 Ländern, 150 Berufe, mehr als 30 Ausbildungsgänge – willkommen in der lebendigen Welt der Universitätsmedizin. Willkommen zur Entdecken Sie die Universitätsmedizin Münster...
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Thea Jacobs @theajacobs.bsky.social · 10/09/2025
Super cool work from our institute!
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Katja Röper @katjaroeper.bsky.social · 27/08/2025
Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...
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Emily Kolenbrander Ho @emkolen.bsky.social · 22/07/2025
pYtags - our in vivo biosensors for receptor tyrosine kinases - in all their beauty on the cover of Cell Reports! Read more here: www.cell.com/cell-reports...
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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 15/07/2025
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
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Universität Münster @uni-muenster.de · 11/07/2025
Using a simple model – #FruitFly eggs – biologist @theajacobs.bsky.social is investigating how cells build connections, and thus form tissues that only allow certain substances or cells to pass through. Here, she provides insight into her day-to-day research. @sfb1348.bsky.social uni.ms/d3ry0
uni.ms
How does the yolk get into the egg? Studies on the fruit fly | Thea Jacobs
Cells build connections in organisms, and thus, form tissues that only allow certain substances or cells to pass through. In her doctoral thesis, biologist Thea Jacobs has carried out investigations o...
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Universität Münster @uni-muenster.de · 11/07/2025
Neurobiologist Bente Winkler @b-wink.bsky.social investigates how the brain reacts to #neuroinflammation. For this, she is using genetically modified #Drosophila flies that enable an artificial activation of the immune system. Read more: uni.ms/48q7k
uni.ms
Inflammation in the brain: My research on the fruit fly | Bente Winkler
Neurobiologist Dr Bente Winkler is investigating how fruit fly brains react to inflammation. To do this, she is using genetically modified fruit flies in which a reaction of the immune system can be a...
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SFB 1348 @sfb1348.bsky.social · 07/07/2025
Exciting @sfb1348.bsky.social with Katja Rust (Philipps-University Marburg) on Thursday. She will speak about "A single-cell analysis of Hh and EGFR-RAS: Independent signaling pathways prevent tumorigenesis". More information: www.uni-muenster.de/SFB1348/en/i... Everyone is welcome!
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Thea Jacobs @theajacobs.bsky.social · 04/07/2025
It’s #FluorescenceFriday again! @maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...
Confocal image of Ajuba in Drosophila follicle cells. The Protein localizes at Tricellular Junctions.
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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 24/06/2025
🥰 Self-supervised, label-free 3D cell imaging is here Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!). And many thanks to my other awesome co-authors🙏 elifesciences.org/articles/99848
actu.epfl.ch
Self-supervised, label-free 3D cell imaging is here
EPFL researchers introduce CellSeg3D, a self-supervised tool for 3D cell segmentation in fluorescence microscopy, eliminating the need for manual labeling and enhancing accessibility for various biolo...
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SFB 1348 @sfb1348.bsky.social · 29/04/2025
Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de We can't wait to see you there! crc1348-conference.ycode.site #DynamicCellularInterfaces #Münster
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Stefan Luschnig @luschnig.bsky.social · 24/03/2025
Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely! Epithelial biology: Holding the corners together: shorturl.at/cMziC @sfb1348.bsky.social @uni-muenster.de
cell.com
Epithelial biology: Holding the corners together
A new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work res...
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epithelial mechanics fan club @epimechfc.bsky.social · 09/03/2025
This dot is a region that intersect multiple cell junctions in an epithelia. These dots act as tiny anchors of cell contacts and they’re critical for epithelial coherence during homeostasis AND development. I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.
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Bardin Lab @bardinlab.bsky.social · 07/03/2025
Paris Now #StandUpForScience @standupforscience.bsky.social @standupforscifr.bsky.social compliments of sulekh.bsky.social one of our postdocs!
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Alushin Lab @alushinlab.bsky.social · 18/02/2025
Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6h
bit.ly
Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature
Afadin strengthens adherens junctions by stabilizing cadherin-catenin complex clusters on curved F-actin.
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Being Liberal ®🗽🏳️‍🌈 @beingliberal.bsky.social · 02/03/2025
#science - in the light of potential enshittification of #PubMed - Ihere's an European alternative to PubMed - www.europepmc.org It's not censored or brought down by would-be-dictators.🧪
europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
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Stefan Luschnig @luschnig.bsky.social · 17/02/2025
Our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social shows how relaxation of tension, rather than active actomyosin-based force, allows opening of cell #vertices to increase #epithelial permeability shorturl.at/Wnb2n @sfb1348.bsky.social @uni-muenster.de
cell.com
Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions restricts epithelial permeability in Drosophila
Cell vertices integrate forces in epithelia and play key roles in regulating barrier function. Jacobs et al. show that modulation of actomyosin contractility at cell vertices controls tricellular junc...
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Vítor Yang @vitoryang.bsky.social · 21/01/2025
It's always mesmerizing seeing how these group of cells move. ℹ️Border cells invading through nurse cells ℹ️Drosophila S9 egg chambers
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Thea Jacobs @theajacobs.bsky.social · 22/11/2024
#fluorescentfriday with a Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta). We use the follicle epithelium as a model to study junction remodelling and barrier formation. Check out our preprint on how Rok regulates paracellular permeability: www.biorxiv.org/content/10.1...
Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta).
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Teun Huijben @teunhuijben.bsky.social · 13/11/2024
5/ 🐣 With this technology at hand, we build the Virtual Embryo Zoo (virtual-embryo-zoo.sf.czbiohub.org), a showcase of cell-tracking datasets from 6 model organisms, including zebrafish and Drosophila. Explore them interactively, trace lineages, and download tracking data for further analysis! 🐠🐭
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