Nature Neuroscience - Charbonneau et al. compare how the insula is structured and functions in humans, monkeys and rodents, revealing similarities and differences across species that are likely to...

Human neurodevelopment is a continuous process that begins prenatally and extends into postnatal life. Current transcriptomic datasets are limited, fragmented across analytical frameworks, precluding ...

The human thalamus is composed of multiple nuclei that differ in structure and function. From early development onwards, these nuclei form reciprocal, nucleus-specific connections with the cerebral co...

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

The origins of the cortical connectome’s complex topology and region-specific topography remain unclear, motivating a search for underlying physical principles. A neural-field-theory model that prioritizes connections between regions that facilitate the excitation of the resonant geometric eigenmodes of the cortex and reproduces topological and topographical features of diffusion-MRI and tract-tracing connectomes across five mammalian species and multiple spatial scales, indicating a universal geometric basis for connectome architecture.

The effects of different choices on preprocessing pipelines for functional connectomics remain unclear. Here, the authors systematically evaluate a multitude of pipelines on resting-state fMRI, reveal...

We provide the first in vivo visualization of the prefrontal cortex's short-range connections by guiding diffusion tractography with past histological findings. This approach accurately reconstructs ...

National Institutes of Health (NIH) Office of Science Policy (OSP): Request for Information on Draft NIH Controlled-Access Data Policy and Proposed Revisions to NIH Genomic Data Sharing Policy

Cruddas et al. reviewed how core concepts from wave physics relate to cortical wave physiology and psychology. They examined how cortical waves emerge, how they facilitate coordinated, hierarchical, a...

Tissue stiffness mediated by Piezo1 is shown to regulate the expression of diffusive guidance cues in the developing Xenopus laevis brain, revealing a crosstalk between mechanical signals and long-ran...

Nine in 10 Australian researchers had their “ideas grant” applications rejected last year, even as Australia’s medical investment fund sits on $5 billion more than it was designed to hold.

YouTube video by Organization for Human Brain Mapping

Long-range cerebellar outputs are critical for shaping brain-wide functional architecture, influencing motor, cognitive, and affective domains. Pro...

Navigate the rise and fall of research topics over five decades using our interactive map, which is based on a semantic analysis of nearly 350,000 abstracts.

YouTube video by Stuart0193