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Bratislav Misic

@misicbata.bsky.social
842 followers 581 following 178 posts

Montreal Neurological Institute - McGill University netneurolab.github.io

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Reposted by Bratislav Misic
Golia Shafiei @goliashf.bsky.social · 8h
So excited that our work is now published in PLOS Biology!! 🎉 Check out the final version here: doi.org/10.1371/jour... And for a bit more context and what we found, here’s our earlier thread: bsky.app/profile/goli...
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Francesco Poli @francescopoli.bsky.social · 27/09/2026
I can't overstate the importance of this toolbox & this paper! Really amazing stuff
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Bratislav Misic @misicbata.bsky.social · 25/09/2026
Spatial organization of AQP4 water channel expression in the human brain | doi.org/10.1126/scia... Aquaporins are a key component of the glymphatic system. How are they distributed + how do they relate to brain function and dysfunction? ⤵️
doi.org
Spatial organization of AQP4 water channel expression in the human brain
Aquaporin-4 (AQP4) water channels support the glymphatic system, a brain-wide pathway that clears cerebral waste products. Here, we use AQP4 gene expression to reconstruct a whole-brain glymphatic-rel...
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Bratislav Misic @misicbata.bsky.social · 24/09/2026
netneurotools: a trainee-oriented approach to network neuroscience | doi.org/10.1038/s415... Our lab’s internal toolkit for accomplishing everyday tasks in brain imaging @natprot.nature.com ⤵️
doi.org
netneurotools: a trainee-oriented approach to network neuroscience - Nature Protocols
This is a Perspective covering a Python toolbox for neuroscience research that enables users to fetch datasets, construct networks and null models, estimate graph metrics, fit statistical models and v...
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Rosy Favicchio @rosyf.bsky.social · 15/09/2026
netneurotools is a Python toolkit that has been continuously developed by lab trainees as a set of tools to navigate the complex informatics ecosystem of brain imaging. @natprot.nature.com @misicbata.bsky.social 🧪 🧠 #imaging
nature.com
netneurotools: a trainee-oriented approach to network neuroscience - Nature Protocols
This is a Perspective covering a Python toolbox for neuroscience research that enables users to fetch datasets, construct networks and null models, estimate graph metrics, fit statistical models and v...
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PLOS Biology @plosbiology.org · 16/06/2026
#Aging drives changes in the #brain and #metabolism, but how independent are these effects? This study by @asafarahani.bsky.social, @misicbata.bsky.social &co identifies two axes of brain-body associations, each primarily related to age or metabolic health. 🧪#AcademicSky plos.io/4eoIu3L
A series of brain maps, showing the association between one of the identified biomarkers relating sub-regional brain features to physiological, functional, and structural factors.
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PLOS Biology @plosbiology.org · 16/06/2026
#Aging drives changes in the #brain and #metabolism, but how independent are these effects? This study by @asafarahani.bsky.social, @misicbata.bsky.social &co identifies two axes of brain-body associations, each primarily related to age or metabolic health. 🧪#AcademicSky plos.io/4eoIu3L
A series of brain maps, showing the association between one of the identified biomarkers relating sub-regional brain features to physiological, functional, and structural factors.
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Reposted by Bratislav Misic
Alex Fornito @alexfornito.bsky.social · 07/06/2026
Our latest, led by @ivaili.bsky.social out now in Nature Mental Health using normative modelling to understand the heterogeneity of atypical FC in autism. Peep the thread...
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Armin Raznahan @bogglerapture.bsky.social · 28/05/2026
Do humans show sex differences in brain activation? If so, are these task-specific or general — and do they relate to sex differences in brain anatomy and behavior? We dove deep into these questions in a new paper just out in Nature Communications | tinyurl.com/3rdrb524
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Andrea Luppi, PhD @loopyluppi.bsky.social · 20/05/2026
Delighted that our paper about benchmarking gene expression 🧬 in macaque brain 🐒🧠(www.science.org/doi/10.1126/...) was selected for this year's Brain Star Award of the Canadian Neuroscience Association 🇨🇦 - what an honour to be named among such talented scientists!
science.org
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Leon Lotter @leondlotter.de · 07/05/2026
My most recent and biggest work so far is finally out as a preprint! 🧠🧵 *Linking human brain functional connectivity to underlying neurotransmission* doi.org/10.64898/202... 1/n TL;DR below ↓ #neuroskyence #neuroimaging #MedSky #PsySciSky
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/04/2026
Benchmarking spatial interpolation methods for brain maps www.biorxiv.org/content/10.64898/20…
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Alain Dagher @alaindagher.bsky.social · 17/04/2026
Comparative anatomy of brain metabolism in human and macaque (and other species). The dichotomy between glucose as fuel and glucose for tissue building is conserved across species. @moohebatpe.bsky.social and @misicbata.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
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Thomas Yeo @bttyeo.bsky.social · 09/04/2026
We develop a new TMS targeting algorithm and test it in an open label trial in a treatment-resistant depression population with high comorbidities. Preprints by @rubykong92.bsky.social Phern-Chern Tor 1. doi.org/10.1101/2025... 2. doi.org/10.64898/202... Our new approach ...
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Marc L Seal @parkvillegeek.bsky.social · 08/04/2026
👀 Structure-function coupling in the human brainstem | bioRxiv www.biorxiv.org/content/10.6...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 07/04/2026
Structure-function coupling in the human brainstem www.biorxiv.org/content/10.64898/20…
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Thomas Yeo @bttyeo.bsky.social · 27/03/2026
Do you censor high motion frames in fMRI? In two preprints by @twktan.bsky.social @mandymejia.bsky.social, we find that we may be censoring too much! doi.org/10.64898/202... arxiv.org/html/2603.07... Strict censoring leads to worse personalized TMS targets than no censoring, even with high motion!
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Laura Lewis @lauradata.bsky.social · 20/03/2026
Our lab has an opening for a full-time research assistant, to work on human neuroimaging techniques and the neuroscience of sleep! To apply: massgeneralbrigham.wd1.myworkdayjobs.com/en-US/MGBExt...
massgeneralbrigham.wd1.myworkdayjobs.com
Clinical Research Coordinator
Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to adva...
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Eric Ceballos @cebric.bsky.social · 18/03/2026
Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function #neuroskyence #compneuro #neuroscience
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Alessandro Gozzi @gozziale.bsky.social · 18/03/2026
📢 New preprint from the lab🧠 ▶️doi.org/10.64898/2026.03.12.710517 What does fMRI connectivity actually reflect at the neural level? The natural intuition is: more neural activity = more connectivity! Using cortical perturbations we show this is not necessarily the case: sometimes less is more! 👇🧵
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Alessandro Gozzi @gozziale.bsky.social · 17/03/2026
Our work on gene therapy for creatine transporter deficiency is now online in #Brain ➡️https://doi.org/10.1093/brain/awaf275 In this study we (i) characterize network-level and behavioral alterations in a common form of monogenic #autism and (ii) test whether gene therapy can rescue these deficits 🧵
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Randy McIntosh @ar0mcintosh.bsky.social · 16/03/2026
The program is coming together well for the Brain Connectivity Workshop www.bcw2026.org/program. This will be our 25th year! Consider coming just before the #OHBM annual meeting. #Neuroscience
bcw2026.org
Program — BCW 2026: June 10-12
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Bratislav Misic @misicbata.bsky.social · 17/03/2026
Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️
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Andrea Luppi, PhD @loopyluppi.bsky.social · 13/03/2026
Just out in @natneuro.nature.com! 🧠 “Competitive interactions shape mammalian brain network dynamics and computation” www.nature.com/articles/s41... Is large-scale brain communication purely cooperative — or is competition a core organizing principle? We built 🧠 models to find out: read on🧵👇
nature.com
Competitive interactions shape mammalian brain network dynamics and computation - Nature Neuroscience
Brain network architecture may balance cooperation and competition across circuits. Here the authors use computational whole-brain modeling across three species to show that models with competition ar...
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Alessandro Gozzi @gozziale.bsky.social · 12/03/2026
🚀 We are hiring: a PhD position is available in my lab (gozzilab.it) at @iitalk.bsky.social, Italy. Project: large-scale brain network mapping in behaving mice using functional ultrasound imaging (FUSI). 📅 Deadline: March 31 🔗 tinyurl.com/4jtetxa9 Reshares appreciated 😊
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Bratislav Misic @misicbata.bsky.social · 11/03/2026
Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/jour... How do diverse synapses relate to the spatial patterning of whole-brain dynamics? Justine Hansen explores @plosbiology.org ⤵️
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Bratislav Misic @misicbata.bsky.social · 11/03/2026
Spatial organization of AQP4 channels in the human brain: links with perfusion, edema, and disease vulnerability | doi.org/10.64898/202... Aquaporins are a key component of the brain’s glymphatic system. How are they distributed and how do they relate to healthy brain function and dysfunction? ⤵️
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Rick Betzel @richardfbetzel.bsky.social · 05/03/2026
🚨Another new one from the lab! Cascades and convergence: Dynamic signal flow in a synapse-level brain network We simulate sensory cascades in a bona fide biological neural network. With Caio Seguin, Maria Grazia Puxeddu, and @misicbata.bsky.social! journals.plos.org/complexsyste...
journals.plos.org
Cascades and convergence: Dynamic signal flow in a synapse-level brain network
Author summary To understand how the brain processes and merges information from our senses, we need more than just a “wiring map” of its connections; we need to see how signals actually travel throug...
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Alessandro Gozzi @gozziale.bsky.social · 05/03/2026
fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs) But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995 🧵1/n
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Rick Betzel @richardfbetzel.bsky.social · 28/02/2026
🚨 New Paper: Controlling the Human Connectome with Spatially Diffuse Input Signals Now in press at Communications Biology! www.nature.com/articles/s42...
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Mallar Chakravarty @mallarchak.bsky.social · 24/02/2026
New preprint 📣 Do you use the @alleninstitute.org mouse brain connectome? In work led by Vikram Nathan we found issues with existing connectome representations, fixed them, showed the impact on connectome measures. Do you wonder what they are? Do you wonder what they do? tinyurl.com/5y9mft4e
media.tenor.com
a man wearing headphones is sitting in front of a microphone .
ALT: a man wearing headphones is sitting in front of a microphone .
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 20/02/2026
Spatial organization of AQP4 channels in the human brain: links with perfusion, edema, and disease vulnerability www.biorxiv.org/content/10.64898/20…
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Andreas Horn @andreashorn.org · 20/02/2026
"You see what you look for, and you look for what you know." We are proud to release FOCUS: a 100 μm deformable human subcortical atlas precisely registered to MNI space. www.biorxiv.org/content/10.6...
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Alessandro Gozzi @gozziale.bsky.social · 17/02/2026
🚨Do we need a large, expensive MRI scanner to map whole-brain networks in the mouse? Not necessarily! In our new preprint ▶️ tinyurl.com/3a2h4r9f we show that transcranial functional ultrasound (fUSI) can map connectome-scale networks with striking agreement to fMRI 🧵👇
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Bratislav Misic @misicbata.bsky.social · 13/02/2026
Inter-individual variability of neurotransmitter receptor and transporter density in the human brain | doi.org/10.1007/s004... How do neuroreceptor distributions vary across people?
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PLOS Biology @plosbiology.org · 13/02/2026
How do diverse synapses relate spatially to whole-brain dynamics? @misicbata.bsky.social &co map ~1 billion synaptic puncta from a single mouse brain onto #hemodynamic features, revealing links between #synapse features, #brain networks & synaptic engagement @plosbiology.org 🧪 plos.io/4rmeef6
Synapse type density in the mouse brain.  PSD95 and SAP102, two postsynaptic scaffolding proteins expressed at excitatory synapses, were fluorescently imaged at single-punctum resolution across the whole mouse brain. Top row: Axial, coronal, and sagittal view of the 137-region parcellation used for analyses involving tract-tracing data (left) and the 88-region parcellation used for analyses involving fMRI data (right). Regions are coloured and labeled according to ontological structure. Other roaws show axial, coronal, and sagittal views of mean long-lifetime PSD95 synapse density, mean short-lifetime PSD95 synapse density, and mean SAP102 synapse density, mapped to both 137- and 88-region parcellations.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 03/02/2026
Integrating Functional Transdiagnostic Dimensions of Psychopathology with Cortical Organization www.biorxiv.org/content/10.64898/20…
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PLOS Biology @plosbiology.org · 02/02/2026
How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8
Left:  Pathways involved in brain energy metabolism. Energy metabolism refers to processes involved in energy production from nutrient molecules. Glucose is the main energy source in the brain under normal physiological conditions. Glucose entering brain cells can be utilized in three parallel pathways. It can be processed through glycolysis to produce 2 ATP and 2 pyruvate molecules (blue). Lactate dehydrogenases catalyze the interconversion of lactate and pyruvate (purple). Pyruvate is transported into mitochondria, where it enters the TCA cycle to generate high-energy electron carriers NADH and FADH2 (green), driving the complete oxidation of glucose through the mitochondrial electron transport chain (red). Glucose entering the brain can also enter the PPP. PPP is an anabolic pathway that uses glucose to produce 5-carbon sugars and NADPH, an essential co-factor used in nucleotide and lipid biosynthesis (yellow). Glucose can also be stored in the form of glycogen via glycogen synthase, a process mainly active in astrocytes. Right: Energy pathway maps. Colors show z-scored mean expression values across all genes in each pathway. ppp, pentose phosphate pathway; tca, tricarboxylic acid cycle; oxphos, oxidative phosphorylation; lactate, lactate metabolism and transport.
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Giulia Baracchini @giuliaabaracc.bsky.social · 30/01/2026
Now in press one of my last PhD projects! We traced the neurobiological profile of fMRI BOLD signal variability, a measure that has been related to age, behaviour, disease status, but had not yet been fully contextualised within the brain's multiscale architecture. www.nature.com/articles/s41...
nature.com
The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization - Nature Communications
Baracchini et al. reveal that temporal variability in fMRI brain signals encodes biologically meaningful information across spatial and temporal scales, highlighting its role in healthy brain function...
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Annie G. Bryant @anniegbryant.bsky.social · 27/01/2026
The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...
Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.
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Alex Fornito @alexfornito.bsky.social · 26/01/2026
Our latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out: www.biorxiv.org/content/10.6... For a full thread, see: x.com/_victorbarne...
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Alex Fornito @alexfornito.bsky.social · 08/01/2026
🔥🔥Exciting news!!!🔥🔥 The invited speaker schedule for the 2026 Noosa Brain Workshop has been finalised! Commuter registrations are still available, but close Feb 1. 3 more weeks to get in!!! Register here: www.monash.edu/turner-insti...
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Joëlle Bagautdinova @joelleba.bsky.social · 05/01/2026
Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels? Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202... Thread below 🧵
doi.org
Anatomical White Matter Tracts Span the Cortical Hierarchy to Support Cognitive Diversity
Long-range white matter (WM) tracts support cognition by enabling communication between distant cortical regions, which are organized along a hierarchy defined by the sensorimotor-to-association (S-A)...
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Bratislav Misic @misicbata.bsky.social · 18/12/2025
netneurotools: a trainee-oriented approach to network neuroscience | doi.org/10.1101/2025... Our lab’s internal toolkit for accomplishing everyday tasks in brain imaging ⤵️
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Alain Dagher @alaindagher.bsky.social · 11/12/2025
Cortical expansion and genetic risk for PD. Led by Houman Azizi and Nooshin Abbasi. With @ptenigma.bsky.social @misicbata.bsky.social @yasharneuro.bsky.social @ndrewvo.bsky.social and many others www.medrxiv.org/content/10.6...
medrxiv.org
Brain size links neurodevelopment to neurodegeneration in Parkinson's disease
Genetic studies have advanced our understanding of Parkinson's disease (PD) pathogenesis, establishing a role for autophagy and lysosomal dysfunction. However, how genetic risk translates into neurona...
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Alex Fornito @alexfornito.bsky.social · 11/12/2025
Come and join our team! We are looking for a Research Officer to help with recruitment and assessment on a large-scale human brain imaging study: careers.pageuppeople.com/513/cw/en/jo...
careers.pageuppeople.com
Job Search
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Andrea Luppi, PhD @loopyluppi.bsky.social · 08/12/2025
🧠 Excited to share our latest preprint: Automated Brain Mapping with AI Experts!🤖 www.biorxiv.org/content/10.6... Ever wanted to summarise the cognitive/systems neuroscience literature beyond MRI and PET? Ever wished we could do the same for macaque 🐒 and mouse 🐭 ? Read on! 🧵👇
biorxiv.org
Cognitive cartography of mammalian brains using meta-analysis of AI experts
The complexity of the brain is increasingly mirrored by the complexity of the neuroscientific literature, yet no individual mind can fully grasp the diversity of scales, methodologies and model organi...
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Department of Engineering, University of Cambridge @eng.cam.ac.uk · 03/12/2025
Dr Andrea Luppi is one of 25 early-career researchers recognised for their outstanding scientific contributions and commitment to mentoring and community-building in neuroscience. @thetransmitter.bsky.social @stjohnscollege.bsky.social www.eng.cam.ac.uk/news/dr-andr...
eng.cam.ac.uk
Dr Andrea Luppi named ‘Rising Star in Neuroscience 2025’
Dr Andrea Luppi is among 25 researchers worldwide to be recognised by The Transmitter – a US-based publication for the neuroscience community. Rising Stars in Neuroscience 2025 honours early-career re...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 03/12/2025
Cognitive cartography of mammalian brains using meta-analysis of AI experts www.biorxiv.org/content/10.64898/20…
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Sylvain Baillet @sylvainbaillet.bsky.social · 28/11/2025
Please repost: another kind of Black-Friday deal!
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