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Moohebat Pourmajidian

@moohebatpe.bsky.social
31 followers 66 following 1 posts

Phd student in Neuroscience Montreal Neurological Institute, McGill Univeristy

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Reposted by Moohebat Pourmajidian
Valentin Riedl @vavatin.bsky.social · 24/06/2026
Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Moohebat Pourmajidian @moohebatpe.bsky.social · 16/06/2026
Last day presenting our work on energy metabolism and cross species lifespan trajectories at #OHBM2026 Come by if you'd like to chat. Poster #1113 Or check out our paper and the recent preprint here: doi.org/10.1371/jour... doi.org/10.64898/202...
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Marc L Seal @parkvillegeek.bsky.social · 11/06/2026
I am spending way toooo long playing around with this wonderfully curated list of R colour palettes. Color palettes emilhvitfeldt.github.io/r-color-pale...
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Marc L Seal @parkvillegeek.bsky.social · 11/11/2025
👀 Morphogenesis and morphometry of brain folding patterns across species | bioRxiv www.biorxiv.org/content/10.1...
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Valerie Jill Sydnor @valeriejsydnor.bsky.social · 11/11/2025
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
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Alex Fornito @alexfornito.bsky.social · 26/01/2026
Our latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out: www.biorxiv.org/content/10.6... For a full thread, see: x.com/_victorbarne...
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PLOS Biology @plosbiology.org · 20/04/2026
How do #circadian clocks regulate glucose processing? By integrating human metabolite profiling with isotope-tracing in #Drosophila, this study defines daily rhythms in #glucose utilization that are influenced by circadian timing @plosbiology.org 🧪 plos.io/3Olm1M1
The Rush hour (Rush hour of glucose utilization early in the light phase when glucose if funneled into multiple biosynthetic pathways). Human (left) and fly (right), either side of a schematic showing 13C-Glucose feeding into glycolysis, pentose phosphate pathwat or TCA cycle, over a watercolour wash. Image credit Pinky Kain.
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Steven Meisler @stevenmeisler.com · 19/04/2026
Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 www.biorxiv.org/content/10.6...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 17/04/2026
Comparative lifespan trajectories of brain energy metabolism in human and macaque www.biorxiv.org/content/10.64898/20…
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Alain Dagher @alaindagher.bsky.social · 17/04/2026
Comparative anatomy of brain metabolism in human and macaque (and other species). The dichotomy between glucose as fuel and glucose for tissue building is conserved across species. @moohebatpe.bsky.social and @misicbata.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
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Will Snyder @willsnyder.bsky.social · 09/03/2026
How may rare vs. common genetic variation separately influence how our brains – and their complex folding patterns – take shape? 🧬 🧠 Check out our new preprint (and final work from my PhD!) out now! ( + thread below) www.biorxiv.org/content/10.6...
biorxiv.org
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Bratislav Misic @misicbata.bsky.social · 11/03/2026
Spatial organization of AQP4 channels in the human brain: links with perfusion, edema, and disease vulnerability | doi.org/10.64898/202... Aquaporins are a key component of the brain’s glymphatic system. How are they distributed and how do they relate to healthy brain function and dysfunction? ⤵️
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Andrea Luppi, PhD @loopyluppi.bsky.social · 13/03/2026
Just out in @natneuro.nature.com! 🧠 “Competitive interactions shape mammalian brain network dynamics and computation” www.nature.com/articles/s41... Is large-scale brain communication purely cooperative — or is competition a core organizing principle? We built 🧠 models to find out: read on🧵👇
nature.com
Competitive interactions shape mammalian brain network dynamics and computation - Nature Neuroscience
Brain network architecture may balance cooperation and competition across circuits. Here the authors use computational whole-brain modeling across three species to show that models with competition ar...
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PLOS Biology @plosbiology.org · 02/02/2026
How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8
Left:  Pathways involved in brain energy metabolism. Energy metabolism refers to processes involved in energy production from nutrient molecules. Glucose is the main energy source in the brain under normal physiological conditions. Glucose entering brain cells can be utilized in three parallel pathways. It can be processed through glycolysis to produce 2 ATP and 2 pyruvate molecules (blue). Lactate dehydrogenases catalyze the interconversion of lactate and pyruvate (purple). Pyruvate is transported into mitochondria, where it enters the TCA cycle to generate high-energy electron carriers NADH and FADH2 (green), driving the complete oxidation of glucose through the mitochondrial electron transport chain (red). Glucose entering the brain can also enter the PPP. PPP is an anabolic pathway that uses glucose to produce 5-carbon sugars and NADPH, an essential co-factor used in nucleotide and lipid biosynthesis (yellow). Glucose can also be stored in the form of glycogen via glycogen synthase, a process mainly active in astrocytes. Right: Energy pathway maps. Colors show z-scored mean expression values across all genes in each pathway. ppp, pentose phosphate pathway; tca, tricarboxylic acid cycle; oxphos, oxidative phosphorylation; lactate, lactate metabolism and transport.
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Stuart Oldham @stuartoldham.bsky.social · 25/06/2025
For those at OHBM, check out my posters and talk! Today and tomorrow I (and maybe @garedaba.bsky.social) will be presenting my poster (1012) on our work linking fetal gene expression to neonatal connectome organisation 🧬🧠👶🌐 1/2 #OHBM #OHBM2025 (preprint here www.biorxiv.org/content/10.1... )
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Neuroskeptic @neuroskeptic.bsky.social · 08/05/2025
Autonomic physiological coupling of the global fMRI signal www.nature.com/articles/s41... "The global fMRI signal is a substantial component of the arousal response governed by the autonomic nervous system."
nature.com
Autonomic physiological coupling of the global fMRI signal - Nature Neuroscience
The brain and body are necessarily connected. Here the authors show that brain blood flow and electrical activity are coupled with systemic physiological changes in the body.
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Annie G. Bryant @anniegbryant.bsky.social · 04/05/2025
🎨🧑‍🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊 anniegbryant.github.io/subcortex_vi...
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Boris Bernhardt @borismontreal.bsky.social · 30/03/2025
Study human brain structure and function with our new open access 7T MRI dataset led by superstar scientist @donnagift.bsky.social ↙️
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Audrey Luo @audreycluo.bsky.social · 20/03/2025
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1... 1/n
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Sidhant Chopra @sidchop.bsky.social · 24/03/2025
🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia" medrxiv.org/content/10.1... We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
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Alain Dagher @alaindagher.bsky.social · 18/03/2025
New: Energy use shapes brain organization and development. We use gene expression maps from the @alleninstitute.bsky.social Human Brain Atlas to map the main energy metabolism pathways in the brain. Led by @moohebatpe.bsky.social @misicbata.bsky.social @goliashf.bsky.social and Justine Hansen 🧵
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