Internship - Pönisch Lab

The force-activated ion channels underlie the senses of touch and proprioception. Now scientists are using them as a tool to explore molecular mechanisms at work in internal organs…

Tissue stiffness mediated by Piezo1 is shown to regulate the expression of diffusive guidance cues in the developing Xenopus laevis brain, revealing a crosstalk between mechanical signals and long-ran...

The pioneer factor Zelda activates a specific set of developmental and structural genes to end tissue regeneration.

How developmental processes are coordinated in time and space to ensure the robust formation of complex, functional patterns during embryogenesis remains an outstanding question. Investigating this in...

The 2025 Developmental Biology Gordon Research Seminar (GRS) was held on March 29-30 2025. This year, the GRS co-chairs Ana R. Hernandez Rodriguez and

Alongside Research Articles, eLife also publishes scientific discoveries in the form of Tools and Resources papers, Research Advances and Short Reports.

Adult zebrafish possess the ability to regenerate injured hearts through a complex orchestration of molecular and cellular activities. Here, the authors present a single cell and spatially-resolved at...

Mui and team show hyaluronic acid deposition and a soft ECM promote digit regeneration in mice.

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare ...

Tomohisa Toda, Professor für neurale Epigenomik an der Friedrich-Alexander-Universität Erlangen-Nürnberg, erhält den Joseph-Altman-Award.

This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...

Dingare et al. identified a critical role for mannose-dependent glycosylation during early mesoderm specification both in mouse embryonic stem-cell-derived gastruloids and in gastrulating mouse embryo...