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Meike van der Heijden

@meikeesther.bsky.social
2.3K followers 1.5K following 560 posts

Thinking about work, life, and balance. Looking for answers in the cerebellum. Assistant Professor @ Virginia Tech www.vanderheijdenlab.com

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Reposted by Meike van der Heijden
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/09/2026
Cerebellar mitochondrial dysfunction coincides with structural and behavioral abnormalities in 3q29Del mice www.biorxiv.org/content/10.64898/20…
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Meike van der Heijden @meikeesther.bsky.social · 01/10/2026
Intrigued by the cerebellum? Curious about CNVs? Interested in neurodevelopmental disorders? Excited about mitochondria? Don’t miss May’s first preprint! 👇👇👇
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Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 28/09/2026
New from @meikeesther.bsky.social !
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Meike van der Heijden @meikeesther.bsky.social · 17/06/2026
New Preprint: Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation -- Join the ride for some developmental neuroscience, stay for some pretty pictures. doi.org/10.64898/202...
doi.org
Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation
Many neural circuits undergo competitive input selection, a process in which supernumerary connections compete for innervation territory on target cells. This process can create atypical circuits when...
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Meike van der Heijden @meikeesther.bsky.social · 22/09/2026
How I feel when my kids grant me six hours of uninterrupted sleep:
static.klipy.com
Superwoman: I've Got This!
ALT: Superwoman: I've Got This!
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Reposted by Meike van der Heijden
Sweta Agrawal @hokuba.bsky.social · 16/09/2026
Towards this end, Wayne developed a novel behavioral assay, informally referred to as the "Hokie Pokie." Flies are tethered and flying in the dark, and then we raise a platform to contact their legs and see what happens.
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Meike van der Heijden @meikeesther.bsky.social · 05/09/2026
The final challenge in this show is making a meal for ten toddlers. But you can’t make mac&cheese, chicken nuggets, or pizza. Each meal has to have a starch, a protein, and a vegetable. Most food eaten decides the winner.
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Meike van der Heijden @meikeesther.bsky.social · 05/09/2026
A cooking show but instead of a mystery ingredient you have two children crawling around in the kitchen trying to open all the kabinets and climb on the stove.
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Meike van der Heijden @meikeesther.bsky.social · 25/08/2026
This description is the most accurate description of my feelings after my miscarriages. Five years and two babies later, I still sometimes mourn the loss of that initial potential.
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Reposted by Meike van der Heijden
Piali Sengupta @senguptalab.bsky.social · 18/08/2026
Journals: Submit your initial manuscript in any format - yay. Also journals - enter what each author ate for breakfast today, enter names of all the pets they have ever had, and also enter all the other information in the manuscript paragraph by paragraph.
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Meike van der Heijden @meikeesther.bsky.social · 10/08/2026
So when will we see all the ads for jobs for experimentalists that can generate a lot of high quality data? All those AI/ML experts ultimately will need some kind of new data to train different models, right?
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Meike van der Heijden @meikeesther.bsky.social · 10/07/2026
How soon after a paper was sent out for review is too soon to see whether the reviewer’s comments are in? Asking for a friend.
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Meike van der Heijden @meikeesther.bsky.social · 26/06/2026
Very proud of Viviana Hernández-Castañón, postdoc in my lab, for receiving a @dystoniafoundation.bsky.social fellowship. She studies how brain signals evolve in dystonia, a debilitating movement disorder. @fralinbiomed.bsky.social @vtneuroscience.bsky.social news.vt.edu/articles/202...
news.vt.edu
Predicting the onset of a debilitating neurological disorder
Viviana Hernández-Castañón, a postdoctoral associate at the Fralin Biomedical Research Institute at VTC, will use a fellowship from the Dystonia Medical Research Foundation to investigate brain activi...
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Meike van der Heijden @meikeesther.bsky.social · 25/06/2026
Looking forward to presenting our new work at the Hopkins Cerebellum Seminar. DM me for a link if you want to join.
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Meike van der Heijden @meikeesther.bsky.social · 22/06/2026
👀 when connectivity doesn't predict activity news.vt.edu/articles/202...
news.vt.edu
‘A cautionary tale’: Study challenges assumption about brain activity in movement disorders
Meike van der Heijden found that studying activity in Purkinje cells in the cerebellum is not a reliable substitute for understanding activity in connected but less accessible deep cerebellar nuclei c...
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Reposted by Meike van der Heijden
wenchangyue.bsky.social @wenchangyue.bsky.social · 17/06/2026
10 colour palettes I reach for in research charts — curated, and most are colourblind-safe. Categorical + sequential: Okabe-Ito, Paul Tol, Tableau 10, viridis, cividis, magma. Skip default tab10 and rainbow/jet. Which do you swear by? Anything I'm missing? #DataViz #ColorPalette #SciComm
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Meike van der Heijden @meikeesther.bsky.social · 17/06/2026
New Preprint: Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation -- Join the ride for some developmental neuroscience, stay for some pretty pictures. doi.org/10.64898/202...
doi.org
Competitive Olivocerebellar Input Selection Promotes Resilient Circuit Formation
Many neural circuits undergo competitive input selection, a process in which supernumerary connections compete for innervation territory on target cells. This process can create atypical circuits when...
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Reposted by Meike van der Heijden
Fralin Biomedical Research Institute @fralinbiomed.bsky.social · 12/06/2026
Ataxia affects balance, coordination, and mobility. 🧠 @virginiatech.bsky.social researcher Alyssa Lyon is studying whether targeted brain stimulation can improve symptoms by restoring neural communication. See how this work out of @meikeesther.bsky.social's lab could advance ataxia treatment 👇
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Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 09/06/2026
We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/
Congratulations to the 2026 Zara Weinberg Leading Edge Fellows! 
Airi Yoshimoto, Yijun Yang, Alexandra Wells, Simran Virdi, Archana Venkataraman, Emery Usher, Marianna Tannus Ruckert, Wenzhi Song, Kathryn Shelley, Selin Schamiloglu, Julia Peloggia de Castro, Ines Patop, Ruhi Patel, Suranjana Pal, Bernie Simone Owusu Yaw, LaShae Nicholson, Sivapratha Nagappan Chettiar, Dallas Mould, Jessica Moore, Deka Mohamed, Sierra Marable, Annie Ly, Xi (Lucy) Lu, Deirdre Logsdon, Anna Lipkin, Ellen Lesser, Mia Konjikusic, Veronika Kondev, Cayla Jewett, Lucia Ichino, Erin Huiting, Maggie Horst, Isabella Gaeta, Martha Echevarria-Andino, Natasha Claxton, Sarah Cherkaoui, Nikita Bhalerao, Merci Best, Meenakshi Asokan, Alicer Andrew
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Meike van der Heijden @meikeesther.bsky.social · 06/06/2026
Now here’s a useful study 👀
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The Journal of Physiology @jphysiol.bsky.social · 25/05/2026
In this recent study, Alyssa M Lyon from @fralinbiomed.bsky.social and colleagues found that steady-state #Purkinje cell activity has limited predictive power for #cerebellar output in disease 🧠 🔎 Read the research 👇️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
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Meike van der Heijden @meikeesther.bsky.social · 22/05/2026
Incredibly proud of Alyssa Lyon, the first grad student in my lab, for receiving a fellowship from the @ataxiafoundation.bsky.social. Alyssa will record and modulate neurons to investigate how we can make a sick brain better. Read more about Alyssa and her project: news.vt.edu/articles/202...
news.vt.edu
Examining a debilitating neurological disease with brain stimulation
Alyssa Lyon, a doctoral candidate in the Translational Biology, Medicine, and Health Graduate Program, will explore how neuromodulation changes communication between neurons in ataxia, a condition tha...
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Meike van der Heijden @meikeesther.bsky.social · 22/05/2026
Oh like this one: - mentoring students and working with them to make new discoveries - thoroughly thinking about complex problems so we can make a difference for patients health - communicating science within and outside the field in a way that boost understanding of complex ideas
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Dr Kathleen Millen @neurodevkathy.bsky.social · 20/05/2026
🚨🧪🧵URGENT INPUT NEEDED: NIH asks input for next strategic plan-including emphasis on non-animal models (NAMs) to replace animals. Per NIH insider, anti-animal responses now outnumber scientists 200-700x. Please please provide input. Deadline: May 26, 11:59 PM ET. grants.nih.gov/news-events/...
grants.nih.gov
NIH Seeks Input on Framework for Next NIH-Wide Strategic Plan | Grants & Funding
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aric @aghastronaut.com · 17/05/2026
Alien: And how did you run out of water? Earthling: Machines drank it. Alien: Machines. Earthling: We had to feed machines the water. Aliens: So the machines were holding your planet hostage for water. Earthling: No, we made the thirsty machines. They worked for us. Alien: End communication.
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Meike van der Heijden @meikeesther.bsky.social · 15/05/2026
Very excited that Viviana, post-doc extraordinaire in my lab, is an awardee of a DMRF fellowship 🤩
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Reposted by Meike van der Heijden
David Solecki @so-lets-kilab70.bsky.social · 05/05/2026
Hey y’all 👋 repost magic appreciated. The Solecki lab is recruiting multiple postdocs at St. Jude for a chromatin imaging project at the edge of live-cell imaging, neuronal cell biology, chromatin regulation, and quantitative image analysis. Ever dreamed of touring chromatin like this? We CAN 🔥
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Sam Wang @samwang.bsky.social · 05/05/2026
Reminds me of an old piece we wrote on how to avoid spreading falsehoods. Lead with the truth, don't repeat the falsehood, and make sure there's something to fill the void. The neuroscience is all still same enough that it holds true today: www.nytimes.com/2008/06/27/o...
nytimes.com
Opinion | Your Brain Lies to You (Published 2008)
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Meike van der Heijden @meikeesther.bsky.social · 05/05/2026
Our daughter’s favorite plushy is a duck. Terrified we’d ever loose duck, we bought back-up duck for 3X market price. Today our daughter saw 1 cm of back-up duck’s orange foot, recognized it as duck, and demanded to play with it. Needless to say, back-up duck needs to hide better.
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Meike van der Heijden @meikeesther.bsky.social · 02/05/2026
Our 2 year old daughter is very confused their her 3 months old brother’s clothes has pockets but hers don’t. So here I’m teaching a 2yo about the patriarchy.
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Meike van der Heijden @meikeesther.bsky.social · 30/04/2026
Sleep deprived. Married to a Brian and mother to an Oliver, I now study brian cells in the inferior oliver.
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Meike van der Heijden @meikeesther.bsky.social · 24/04/2026
So if you ever run into a nursing mom at a conference. Get her something nice: A coffee A water A glass of wine A cookie with lots of chocolate Tell her her hair looks nice and her outfit looks fire Thank you
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Meike van der Heijden @meikeesther.bsky.social · 24/04/2026
Shortly after posting this my pump broke. Everyone at this meeting now knows I’m a nursing mom. I found a pump. It’s okay. But also everyone I’m talking to tomorrow is going to think about my milk producing qualities…
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Meike van der Heijden @meikeesther.bsky.social · 23/04/2026
Whispering a quiet prayer for the milk I pumped and dumped in the airport nursing station.
media.tenor.com
a man in a suit is holding a container and says sorry to interrupt dairy queen
ALT: a man in a suit is holding a container and says sorry to interrupt dairy queen
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Meike van der Heijden @meikeesther.bsky.social · 23/04/2026
Whispering a quiet prayer for the milk I pumped and dumped in the airport nursing station.
media.tenor.com
a man in a suit is holding a container and says sorry to interrupt dairy queen
ALT: a man in a suit is holding a container and says sorry to interrupt dairy queen
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Meike van der Heijden @meikeesther.bsky.social · 22/04/2026
Truly amazing paper Those reviewer comments 👀
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Melissa Cooper, PhD @melcooperphd.bsky.social · 22/04/2026
Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!
nature.com
Astrocytes connect specific brain regions through plastic networks - Nature
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.
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Meike van der Heijden @meikeesther.bsky.social · 21/04/2026
🚨 new paper alert 🚨 Anatomical connectivity does not always predict functional connectivity in disease — a cautionary tale from the cerebellum Steady-state Purkinje cell activity has limited predictive power for cerebellar output in disease 1/
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Meike van der Heijden @meikeesther.bsky.social · 17/04/2026
Pro-tip: become friends with the people with the best lab swag who also know how to pack home-made chili-crisp to survive air mail. @heatherdsnell.bsky.social
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Meike van der Heijden @meikeesther.bsky.social · 15/04/2026
The parent conundrum: when both kids are quiet and content, do you also take a break and do something for yourself or do you try to get as many chores in before chaos breaks out again?
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Dystonia Medical Research Foundation @dystoniafoundation.bsky.social · 13/04/2026
WE’RE LIVE! The DMRF Auction for Action is officially OPEN! Start bidding now on unforgettable experiences, exclusive getaways, and more—all while supporting critical dystonia research and support programs. Make your first bid today: bit.ly/4mpP1yT #dystonia #dmrf #dystoniafoundation
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Alex DiFeliceantonio @difeliceantonio.bsky.social · 13/04/2026
New preprint from the lab🧵🧪 Eating ultraprocessed foods leads to poor health outcomes, but HOW they do it isn't understood. "HOW?" is important, as "how" can allow targeted policy, reformulaiton, or recommendations to reduce harmful effects. We started to ask that question doi.org/10.64898/202...
doi.org
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Clara Jeffery @clarajeffery.bsky.social · 11/04/2026
Science is good. We should fund it.
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Meike van der Heijden @meikeesther.bsky.social · 11/04/2026
Journal at 8:58pm on Friday night: Return these proofs in 48 hours Me: nope nope nope… the next 48 hours will be dedicated to diaper changes, playgrounds, snack time, and catching up on sleep. See you on Monday 👋
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Meike van der Heijden @meikeesther.bsky.social · 10/04/2026
Lots of bubbles🥂🍾 to celebrate these super stars ✨ receiving two trainee fellowships 💰💰, getting two papers accepted 📄📄, and having two grad school acceptances 👨🏻‍🎓🧑🏼‍🎓 What a way to celebrate coming back from maternity leave 🤱
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Meike van der Heijden @meikeesther.bsky.social · 10/04/2026
I'm looking forward to attending this event in two weeks. fixel.ufhealth.org/dystonia-thi...
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Jimmy Dooley @jimmycdooley.bsky.social · 06/04/2026
tl;dr Babies twitch to learn about their bodies; adults twitch to keep their most specialized skills sharp. So next time you see a twitching paw, know that you could be watching a brain-calibration in progress. As always, check out the full paper for the deep dive! www.cell.com/current-biol...
cell.com
REM-sleep twitching in adults and the maintenance of specialized sensorimotor systems
Blumberg et al. present video evidence of twitching during adult sleep in a diverse sample of animals. Adult twitching appears to selectively involve appendages used for active sensing, mirroring thei...
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Jimmy Dooley @jimmycdooley.bsky.social · 06/04/2026
So why is this the case? We think it’s because active sensing is hard. To use a trunk or a whisker, the brain needs a perfect "internal model" to predict where that sensor is in space. We propose twitches act as biological test pulses to calibrate these models while the animal is asleep.
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Meike van der Heijden @meikeesther.bsky.social · 06/04/2026
Let’s twitch it up! Love this work ♥️
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Nicole Rust @nicolecrust.bsky.social · 04/04/2026
No doubt the ”she” applies to “he” too! fairhalllab.com/careers/how-...
fairhalllab.com
How does she do it?
Can we have it all? Here we are featuring some stories of women who have certainly managed to have a great deal: a successful scientific career and a family. How do they do it? (Note: many of our w…
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