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PessoaBrain

@pessoabrain.bsky.social
9.9K followers 695 following 2.6K posts

Luiz Pessoa, University of Maryland, College Park Neuroscientist interested in cognitive-emotional brain Author of The Entangled Brain, MIT Press, 2022 Author of The Cogitive-Emotional Brain, MIT Press, 2013 Neuroscience & Philosophy Salon (YouTube)

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PessoaBrain @pessoabrain.bsky.social · 21/09/2026
𝗥𝗲𝗰𝗼𝗿𝗱𝗶𝗻𝗴 𝗮𝗰𝗿𝗼𝘀𝘀 𝗯𝗿𝗮𝗶𝗻 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘀 𝗯𝗿𝗮𝗶𝗻𝘄𝗶𝗱𝗲 𝗿𝗲𝗽𝗿𝗲𝘀𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻𝘀 Neuroscientists now recording across the brain are finding what fMRI revealed in humans. Signals are not localized but often all over the brain. (NB: non, it's not everything, everywhere) #neuroskyence www.biorxiv.org/content/10.6...
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PessoaBrain @pessoabrain.bsky.social · 19/09/2026
𝗕𝗿𝗮𝗶𝗻’𝘀 𝗿𝗲𝘀𝘁𝗶𝗻𝗴-𝘀𝘁𝗮𝘁𝗲 𝗶𝘀 𝗻𝗼𝘄 𝘃𝗶𝗲𝘄𝗲𝗱 𝗮𝘀 𝗱𝘆𝗻𝗮𝗺𝗶𝗰 𝗯𝘂𝘁 𝘄𝗵𝗮𝘁 𝗸𝗶𝗻𝗱 𝗼𝗳 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀? We find evidence of both smooth and sharp transitions; latter sharply altered brain dynamics in as few as 1 time step. Link below -->
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PessoaBrain @pessoabrain.bsky.social · 09/09/2026
𝗛𝗼𝘄 𝘁𝗼 𝘁𝗵𝗶𝗻𝗸 𝗼𝗳 𝗯𝗿𝗮𝗶𝗻 𝗺𝗮𝗽𝘀? It seems like a boring visualization change but quite important! fMRI maps have been thresholded for 3+ decades so as to emphasize peaks of activation. This paper argues for a different approach. rdcu.be/B4tikBETdQZa
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Ismael T. Freire @ishmajl.bsky.social · 27/08/2026
Good news if this workshop sounds like your kind of thing: we’ve extended the deadline to Sept 14 (AoE)! 🌱 At #SAB2026, “Wanting What Is Needed” asks how homeostasis shape value, motivation & adaptive behaviour. Come join us in Berlin on Oct 19!! 😊 wwin-workshop.github.io/sab2026/
wwin-workshop.github.io
Wanting What is Needed: From Homeostatic Control to Adaptive Behavior
A SAB 2026 workshop bringing together AI, robotics, neuroscience, physiology, ethology, biology and control theory around homeostasis, allostasis and adaptive behavior.
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The Transmitter @thetransmitter.bsky.social · 19/08/2026
In this episode, @braininspired.bsky.social talks with @marcofacchin.bsky.social about why computational explanations of cognition, though powerful, aren't the only game in town. #neuroskyence www.thetransmitter.org/brain-inspir...
thetransmitter.org
Marco Facchin on theories, explanations in neuroscience
Computational explanations of cognition, though powerful, aren’t the only game in town.
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Mara Mather @maramather.bsky.social · 16/08/2026
Starting September 1, I will be working with a team to start a new research center at the Max Planck Institute for Human Development in Berlin. We currently have a couple of positions posted but there will be more so if you are interested stay tuned and feel free to get in touch.
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PessoaBrain @pessoabrain.bsky.social · 08/08/2026
𝗕𝗿𝗮𝗶𝗻-𝘄𝗶𝗱𝗲 𝗶𝗻𝘁𝗲𝗿𝗮𝗰𝘁𝗶𝗼𝗻𝘀 𝗮𝗻𝗱 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 "Inferring brain-wide interactions using data- constrained recurrent neural network models" Going straight to top of to-read list! #neuroskyence doi.org/10.1016/j.ne...
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PessoaBrain @pessoabrain.bsky.social · 03/08/2026
Harrison gives the state-space modeling tutorial at CNN
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PessoaBrain @pessoabrain.bsky.social · 28/07/2026
𝗡𝗲𝘂𝗿𝗮𝗹 𝘁𝗿𝗮𝘃𝗲𝗹𝗶𝗻𝗴 𝘄𝗮𝘃𝗲𝘀 𝗶𝗻 𝗰𝗼𝗿𝘁𝗲𝘅: 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗮𝗻𝗱 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗿𝗼𝗹𝗲𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻 A must read for systems neuroscience. #neuroskyence doi.org/10.1016/j.ne...
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PessoaBrain @pessoabrain.bsky.social · 16/07/2026
𝗧𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗮𝗻𝗱 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻 Neuroscience & Philosophy Salon discussion now online. Lively debate on @romainbrette.bsky.social 's position. #neuroskyence youtu.be/XV6kCsiq0g0?...
youtu.be
Romain Brette discusses brains and computations
YouTube video by Neuroscience & Philosophy Salon
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PessoaBrain @pessoabrain.bsky.social · 09/07/2026
Join the discussion today! #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 06/07/2026
Don't forget our Salon with Romain Brett discussing 𝘄𝗵𝗮𝘁 𝗯𝗿𝗮𝗶𝗻𝘀 𝗱𝗼 𝗮𝗻𝗱 𝗱𝗼 𝗻𝗼𝘁 𝗱𝗼... July 9. Open to all but you need to register (personal-free/academic zoom account is necessary) #neuroskyence
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Louis Pezon @lpezon.bsky.social · 30/06/2026
Both brains and RNNs can re-use components of computation across similar tasks or contexts. But what exactly are those “shared components”? How can they be used to solve several tasks? We address these questions in a new preprint with @avm.bsky.social! Link: www.biorxiv.org/content/10.6...
biorxiv.org
Interpretable compositional computation with recurrent neural networks
Flexible cognition utilizes reusable components to enable rapid adaptation of behavior to different contexts or tasks. Analysis of artificial neural networks trained on multiple tasks suggested that t...
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Ricard Solé @ricardsole.bsky.social · 27/06/2026
What makes a new kind of mind possible? In this @royalsocietypublishing.org paper, the authors explain why cognitive transitions are not just moments when animals became smarter, but evolutionary shifts that opened new spaces of cognition. @eplantec.bsky.social pmc.ncbi.nlm.nih.gov/articles/PMC...
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Ran Blekhman @blekhman.bsky.social · 27/06/2026
I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...
open.substack.com
My Peer Review of The 1%
I wanted to like QED's new 1% ranking. I don't.
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PessoaBrain @pessoabrain.bsky.social · 27/06/2026
NIH grants?? Now counting on wishes...
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PessoaBrain @pessoabrain.bsky.social · 26/06/2026
*Are rodents a good model of the amygdala?* Probably not. Important comparative anatomy findings by Freixes, Medina, Desfilis. At the VI international Congress of Psychobiology, Seville, Spain.
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PessoaBrain @pessoabrain.bsky.social · 26/06/2026
*Hippocampus: action at a distance* Really beautiful talk by Lynn Nadel about the hippocampus and how it supports acting based on past and future information. At the VI international Congress of Psychobiology, Sevilla, Spain.
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PessoaBrain @pessoabrain.bsky.social · 15/06/2026
𝗪𝗵𝗮𝘁 𝗮𝗿𝗲 𝗯𝗿𝗮𝗶𝗻𝘀, 𝗮𝗴𝗮𝗶𝗻?? Biological systems unlike computers, but what does that mean? Join us in the Neuroscience & Philosophy Salon discussion with Romain Brette of his great book. July 9, noon (USA-EST) Open to all; registration required. umd.zoom.us/meeting/regi... #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 13/06/2026
𝗖𝗮𝗻 𝘀𝗼𝗺𝗲𝗼𝗻𝗲 𝗿𝗲𝗺𝗶𝗻𝗱 𝗺𝗲 𝗮𝗴𝗮𝗶𝗻 𝘄𝗵𝘆 𝘄𝗲 𝗽𝘂𝗯𝗹𝗶𝘀𝗵 𝗽𝗮𝗽𝗲𝗿𝘀 𝘁𝗵𝗲 𝘄𝗮𝘆 𝘄𝗲 𝗱𝗼 and not just deposit what we think is cool work in an archive and move on? Moving on could/should also include going back and improving the work, adding some notes about problems with previous version(s), etc. #bringfunbacktoscience
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PessoaBrain @pessoabrain.bsky.social · 13/06/2026
𝗟𝗲𝗮𝗿𝗻𝗶𝗻𝗴 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝗮𝗹 𝘀𝘆𝘀𝘁𝗲𝗺𝘀 𝗶𝘀 𝗵𝗮𝗿𝗱 But lots of progress being made; this one looks very interesting. arxiv.org/abs/2604.24662
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Yogi Jaeger @yoginho.spore.social.ap.brid.gy · 11/06/2026
RE: spore.social/@yoginho/1159181171092… An updated version of my "Re-Engineering Wimsatt for Limited Beings" is available: zenodo.org/records/20647108 It includes the revisions that were requested during peer-review. Wimsatt is the most important philosopher of science […]
spore.social
Original post on spore.social
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PessoaBrain @pessoabrain.bsky.social · 11/06/2026
𝗕𝗿𝗮𝗶𝗻 𝗮𝘁𝘁𝗿𝗮𝗰𝘁𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Does it support a modular and hierarchical organization as the author support? Not really. Highly distributed and multifunctional findings even in the context of a binary task! #neuroskyence doi.org/10.1038/s415...
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🐭 Danielle Williams 🐹 @okaydaniellle.bsky.social · 17/05/2026
the original hexagon does not include AI, it includes computer science. the 1978 report explicitly defined the connections. (1) doesn’t work when you swap CS for AI. idk where the AI one came from but it can’t be used interchangeably with the one that came from the Sloan Foundation special report.
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PessoaBrain @pessoabrain.bsky.social · 03/06/2026
𝗜𝘀 𝘁𝗵𝗲𝗿𝗲 𝗮𝗻 𝗮𝗹𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝘃𝗲 𝘁𝗼 𝘁𝗵𝗲 𝘁𝗿𝗮𝗱𝗶𝘁𝗶𝗼𝗻𝗮𝗹 𝘃𝗶𝗲𝘄 𝗼𝗳 "𝗲𝗻𝗰𝗼𝗱𝗶𝗻𝗴" 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻? philosophymindscience.org/index.php/ph... #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 03/06/2026
Intervening in complex complex systems
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PessoaBrain @pessoabrain.bsky.social · 02/06/2026
𝗖𝗮𝘂𝘀𝗮𝗹 𝗮𝗻𝗱 𝗱𝗶𝗿𝗲𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗲𝗹𝗲𝗺𝗲𝗻𝘁𝘀 𝗼𝗳 𝗴𝗹𝗼𝗯𝗮𝗹 𝗯𝗿𝗮𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 + 𝗜𝗻𝘁𝗿𝗶𝗻𝘀𝗶𝗰 𝘀𝗽𝗮𝗰𝗲-𝘁𝗶𝗺𝗲 𝗰𝗼𝘂𝗽𝗹𝗶𝗻𝗴𝘀 𝗴𝗼𝘃𝗲𝗿𝗻𝗶𝗻𝗴 𝗺𝘂𝗹𝘁𝗶-𝘀𝗰𝗮𝗹𝗲 𝗰𝗼𝗿𝘁𝗶𝗰𝗮𝗹 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Brain dynamics must-reads by Deisseroth team. www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6... #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 31/05/2026
**How to communicate science to the public?** Angela Potochnik from the Center for Public Engagement with Science leads this workshop. Part of The Society for Philosophy & Neuroscience activities @socphilneuro.bsky.social
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PessoaBrain @pessoabrain.bsky.social · 29/05/2026
So a brain outsider had to say it...
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PessoaBrain @pessoabrain.bsky.social · 27/05/2026
What is the minimal machinery needed for complex, cognition-like behavior? Very cool.
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PessoaBrain @pessoabrain.bsky.social · 22/05/2026
𝗦𝗼 𝗺𝗮𝗻𝘆 𝗯𝗼𝗼𝗸𝘀 𝘁𝗼 𝗿𝗲𝗮𝗱 I've shared book suggestions on the brain, conceptual foundations of biology, and much more. Check out the collection from past years. (interface not perfect at this point). sparkling-trifle-93b8c9.netlify.app
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PessoaBrain @pessoabrain.bsky.social · 17/05/2026
If you use AI to help you peer review a paper, consider that >10 major concerns might be on the excessive side... In my view the reviewer's job is not to tell the authors what to do, but to evaluate the paper in front of them. If it's problematic, reject it!
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PessoaBrain @pessoabrain.bsky.social · 16/05/2026
𝗥𝗲𝗰𝗼𝗻𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝗻𝗴 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝗮𝗹 𝘀𝘆𝘀𝘁𝗲𝗺𝘀 Looking forward to diving into this one. By Durstewitz et al. arxiv.org/abs/2602.16864
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Martin Hebart @martinhebart.bsky.social · 16/05/2026
Finally, today is the day: Josefine Zerbe will present and release our new multi-echo 7T fMRI dataset LAION-fMRI during #VSS2026, with >30 fMRI session per subject and unprecedented stimulus diversity. Come to Talk Room 1 (Scene perception) today at 5:15. Details will follow in a separate thread!
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Paul Kristian LaFosse @lafosse.bsky.social · 15/05/2026
🚨 Ever wanted a simple way to control the activity of thousands of neurons? We introduce an all-optical raster photostimulation method to do just that! w/ @computingnature.bsky.social @marius10p.bsky.social #FluorescenceFriday #neuroskyence www.biorxiv.org/content/10.6... 1/n
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PessoaBrain @pessoabrain.bsky.social · 13/05/2026
Amazingly beautiful, let's do one of the brain+body!
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PessoaBrain @pessoabrain.bsky.social · 13/05/2026
My grant was almost funded but then rev 2 did something...
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PessoaBrain @pessoabrain.bsky.social · 12/05/2026
𝗪𝗵𝗮𝘁 𝗱𝗼𝗲𝘀 𝗮 𝗯𝗿𝗮𝗶𝗻 𝗱𝗼 𝗮𝗻𝘆𝘄𝗮𝘆? Fascinating and profound book on what brains are *not* and what they might be. Including criticism of the computational and predictive brain frameworks. You might not agree with some of it but quite thought provoking.
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PessoaBrain @pessoabrain.bsky.social · 11/05/2026
Rutgers Symposium on the Intersection of Cognitive, Sensory and Affective Neuroscience Introduction by David Zald Great talks.
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PessoaBrain @pessoabrain.bsky.social · 11/05/2026
What are some of the foundational papers in complexity science? It will be interesting to see what neuroscientists will suggest, especially outside some obvious choices (McCulloch and Pitts, etc). Survey is brief.
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Mateo Arias-Vélez @mateoarias.bsky.social · 09/05/2026
Do bonobos have social norms? In my new paper, I argue that bonobos exhibit genuine forms of normativity regulated through shared social mechanisms. Their social life may be far closer to human normativity than we usually assume critica.filosoficas.unam.mx/index.php/cr...
Photo by Cincinnati Zoo
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PessoaBrain @pessoabrain.bsky.social · 09/05/2026
To be provocative, 𝗲𝗺𝗲𝗿𝗴𝗲𝗻𝗰𝗲 might be a sleight of hand if you don't know enough math to understand what it means. There, I said it.
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PessoaBrain @pessoabrain.bsky.social · 09/05/2026
𝗟𝗲𝗮𝗿𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗳𝗿𝗼𝗺 𝗲𝘅𝗽𝗲𝗿𝘁𝘀 Don't miss our upcoming seminars: May 15 and 22 Free for members, join! (discounted for students/postdocs) Additional seminars planned for later this year on additional neuro methods. philandneuro.wildapricot.org
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PessoaBrain @pessoabrain.bsky.social · 08/05/2026
**Circuit dynamics** Yesterday I shared this paper which I believe is in the right direction needed for basic/translational neuro. Here, I outline several ways in which it also falls short. So, right direction but... #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 07/05/2026
𝗠𝗮𝗷𝗼𝗿 𝗱𝗲𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘁𝗵𝗲 𝗹𝗲𝗻𝘀 𝗼𝗳 circuit 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Finally research is considering the functional/ anatomical complexity of the brain. It's not about regions, but how circuits function dynamically. www.cell.com/neuron/abstr... #neuroskyence
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PessoaBrain @pessoabrain.bsky.social · 07/05/2026
Allowed pathways between quantum states determined not just by molecule’s internal symmetries but also its surroundings physics.aps.org/articles/v19... Question for physicists: Is this fundamentally novel; if so are implications minor/major? thanks @seanmcarroll.bsky.social @philipcball.bsky.social
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PessoaBrain @pessoabrain.bsky.social · 27/04/2026
*Complexity in Mental Health* Interplay between brain, behavior and context Organized by Igor Branchi and Francesca Culirulli. Phenomenal location in Erice, Sicily.
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PessoaBrain @pessoabrain.bsky.social · 19/04/2026
𝗣𝘂𝗿𝗽𝗼𝘀𝗲 𝗶𝗻 𝗯𝗶𝗼𝗹𝗼𝗴𝘆 Excellent paper about purposiveness in biology. Important critique of the dynamical systems approach as a "simple" solution to the computationalism approach. Highly relevant to the enactive approach too. doi.org/10.1177/1059...
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PessoaBrain @pessoabrain.bsky.social · 18/04/2026
Great talk by Nadine on perception and imagination. @nadinedijkstra.bsky.social the anterior insula region you found is dorsal or ventral? Without looking again I'm betting dorsal. We've been looking at insula subregions more extensively and finding lots of differences.
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Matthias Michel @matthiasmichel.bsky.social · 17/04/2026
Nadine Dijkstra's talk at the MIT Consciousness Club is now available here: www.youtube.com/watch?v=rciv....
youtube.com
Nadine Dijkstra - Distinguishing imagination and reality in a generative brain
YouTube video by MIT Consciousness Club
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