Aquaporin-4 (AQP4) water channels support the glymphatic system, a brain-wide pathway that clears cerebral waste products. Here, we use AQP4 gene expression to reconstruct a whole-brain glymphatic-rel...

This is a Perspective covering a Python toolbox for neuroscience research that enables users to fetch datasets, construct networks and null models, estimate graph metrics, fit statistical models and v...

Frequently ignored bodily rhythms may be skewing neuroscience experiments

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Human brain architecture is guiding brain-inspired artificial intelligence (AI) and has been treated as an optimal template, whose deviations could ma…

Pagani et al. used cross-species fMRI to reveal two autism subtypes, characterized by lower and higher brain connectivity and linked to synaptic and immune-related pathways, respectively.

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

In his new book, Brette pushes back against theories that describe the brain as a “biological computer.” In this excerpt from Chapter 4, he challenges equating brain evolution with programming…

Despite rapid exploitation of the opportunities that contextualization of brain maps affords, potential limitations have received little attention. In this Roadmap, Royer et al. provide practical guid...

Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...

Brain network architecture may balance cooperation and competition across circuits. Here the authors use computational whole-brain modeling across three species to show that models with competition ar...

Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of sing…

Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia in humans, macaques, marmosets and mice.

The complexity of the brain is increasingly mirrored by the complexity of the neuroscientific literature, yet no individual mind can fully grasp the diversity of scales, methodologies and model organi...

We recognize the outstanding achievements of 25 neuroscientists who stand to shape the field for years to come.