University of Aberdeen PhD to study ALS neuroinflammation using human iPSC models, single cell transcriptomics and imaging to uncover disease mechanisms.

UCL Queen Square Institute of Neurology aims to be an inclusive and supportive workplace that nurtures staff and students to reach their full potential.

ALT: dolly parton is wearing a blonde wig and making a funny face .

Background : Disease-modifying therapies for neurodegenerative disorders are unlikely to succeed once symptoms emerge, as significant neuronal loss has already occurred. Accessible biomarkers that pre...

Dementia Researcher Salon - Organising your Lab for Maximum Efficiency

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

The fourth session of the 2024 European Society of Toxicologic Pathology (ESTP) Congress brought together lectures focused on the use of in vitro and in vivo mo...

The amyloid precursor protein (APP) is processed by multiple enzymes to generate biologically active peptides, including amyloid-β (Aβ), which aggregates to form the hallmark pathology of Alzheimers d...

The trip leaned on a vision of women’s empowerment that is light on substance and heavy on a childlike, girlish silliness

INTRODUCTION Sexism is prevalent in academia and is a crucial factor driving women out of the academic workforce. However, sexism in dementia research remains underexplored. This study aimed to unde.....

The prize is awarded by the German Society of Muscular Diseases.

The role of microglia in amyotrophic lateral sclerosis (ALS) is unclear. Here, the authors show that iPSC microglia from C9orf72-ALS patients are toxic to motor neurons and identify microglial MMP9 as...

Myeloid cells undergo large changes to their gene expression profile in response to inflammatory stimulation. This includes an increase in post-transcriptional modifications carried out by adenosine-t...

This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known and...

INTRODUCTION Cerebrovascular dysfunction plays a critical role in the pathogenesis of dementia and related neurodegenerative disorders. Recent omics-driven research has revealed associations between...

Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds