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Panos Roussos

@panosroussos.bsky.social
275 followers 85 following 6 posts

Genomics. Neuroscience.

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Panos Roussos @panosroussos.bsky.social · 26/09/2026
Thrilled to see the PsychAD package published! 🧠 Launched in 2019: 60+ investigators, 8 institutions, 1,494 human brains—illuminating brain aging and disease. Supported by NIA. Deeply grateful to all donors and families. psych-ad.org www.nature.com/collections/...
psych-ad.org
PsychAD
The PsychAD Consortium builds population-scale, single-cell models of the human brain to uncover the molecular mechanisms behind neuropsychiatric symptoms in Alzheimer’s disease, related dementias, an...
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Panos Roussos @panosroussos.bsky.social · 12/08/2026
Excited to share our new work from #CDNeurogenomics at @sinaibrain.bsky.social @sinaigenetics.bsky.social #MountSinaiPsych, published in @natgenet.nature.com. We map human microglial states across aging and Alzheimer’s disease. Paper: nature.com/articles/s41... PDF: rdcu.be/fzdIr
nature.com
Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease - Nature Genetics
Molecular profiling of myeloid cells from the prefrontal cortex of 1,607 donors with varying degrees of Alzheimer’s disease neuropathology delineates distinct myeloid subtypes and identifies changes associated with aging and disease progression.
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Reposted by Panos Roussos
Nature @nature.com · 27/01/2026
Nature research paper: Biological insights into schizophrenia from ancestrally diverse populations go.nature.com/4pMhb7f
go.nature.com
Biological insights into schizophrenia from ancestrally diverse populations - Nature
Genome-wide association studies incorporating data for populations of African ancestry provide an expanded view of the genetic basis of schizophrenia, which has previously been studied mainly in European and East Asian cohorts.
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Panos Roussos @panosroussos.bsky.social · 21/01/2026
Now out in @nature.com: Biological insights into schizophrenia from ancestrally diverse populations. @sinaibrain.bsky.social @sinaigenetics.bsky.social cs.bsky.social @timbigdeli.bsky.social #CDNeurogenomics #MountSinaiPsych #MillionVeteranProgram and many collaborators Read: rdcu.be/eZ7he
rdcu.be
Biological insights into schizophrenia from ancestrally diverse populations
Nature - Genome-wide association studies incorporating data for populations of African ancestry provide an expanded view of the genetic basis of schizophrenia, which has previously been studied...
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Panos Roussos @panosroussos.bsky.social · 11/03/2025
Congrats @jack-humphrey.bsky.social for isoMiGA now published in @naturegenet.bsky.social @sinaibrain.bsky.social ain.bsky.social @sinaigenetics.bsky.social s.bsky.social @trajnp.bsky.social np.bsky.social #CDNeurogenomics #MountSinaiPsych www.nature.com/articles/s41...
nature.com
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing - Nature Genetics
This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known and...
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Panos Roussos @panosroussos.bsky.social · 11/03/2025
Big congrats to Tereza Clarence for “Multiomic single-cell profiling identifies critical regulators of postnatal brain” now published in @naturegenet.bsky.social @sinaibrain.bsky.social @sinaigenetics.bsky.social #CDNeurogenomics #MountSinaiPsych www.nature.com/articles/s41588-025-02083-8
nature.com
Multiomic single-cell profiling identifies critical regulators of postnatal brain - Nature Genetics
Simultaneous profiling of RNA and chromatin accessibility in single nuclei isolated from human postnatal brain regions from infancy to late adulthood identifies key cellular regulators and nominates t...
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