Most of what is known about the genetics of Parkinson's disease comes from people of European ancestry — a gap that limits how well genetic tests and future therapies will work for everyone else. The largest multi-ancestry genetic study of Parkinson's disease to date, published in The Lancet Neurology, analysed genome and exome sequencing data from more than 99,000 people across 11 genetically inferred ancestries. The study identified causal and risk variants whose frequency differs substantially between populations; roughly 29% of participants with Parkinson's disease came from under-represented, non-European ancestries largely absent from earlier research. Ancestral diversity in Parkinson's disease research is needed to improve diagnostic accuracy and help ensure equitable access to emerging genetically informed therapies. Read the full article by Lange LM, Fang Z-H, Makarious MB, et al, on behalf of the Global Parkinson's Genetics Program (GP2) in The Lancet Neurology here: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(26)00198-5/fulltext?dgcid=youtube_video_vabs_laneur_tln Visit The Lancet at https://www.thelancet.com/?dgcid=youtube_video_vabs_laneur_tln #TheLancet #TheLancetNeurology #ParkinsonsDisease #Genetics #PrecisionMedicine #VideoAbstract * * * Continue this conversation on social! Follow us today at… https://bsky.app/profile/thelancet.com https://Facebook.com/TheLancetMedicalJournal https://Instagram.com/TheLancetGroup https://LinkedIn.com/company/The-Lancet

GP2 hosted a meeting and bioinformatics workshop in Bangkok for 80 clinicians and researchers, strengthening Asian Parkinson’s genetics research by fostering local collaborations, establishing patient cohorts, and training researchers in genetic data analysis.