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Modern amphibians are characterized by an aquatic larval stage that ends abruptly with a period of widespread tissue remodeling (metamorphosis) upon transition to terrestrial adulthood. A transient la...

The color palette viridis is replacing rainbow color schemes in scientific figures, for good reason.

The 2027 Gordon Research Conference on Developmental Biology will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

Polaritons can be optically driven into nonlinear states such as vortices and solitons, with properties like quantized phase jumps and stable shapes, that enable applications in information processing...

Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...

An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill switch holds potential for controlling ...

In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...

Building a mechanistic understanding of cell fate decisions remains a fundamental goal of developmental biology, with implications for stem cell therapies, regenerative medicine and understanding dise...

Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...

The Moon formed from a giant impact of a planetary body, called Theia, with proto-Earth. It is unknown whether Theia formed in the inner or outer Solar System. We measured iron isotopes in lunar sampl...

Researchers have revealed how a genetic circuit may have helped the evolution of insect wings.

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Protein synthesis and clearance are major regulatory steps of gene expression, but their in vivo regulatory roles across the cells comprising complex tissues remains unexplored. Here, we systematicall...