Comparative and functional analyses of Myotis bats uncover unique patterns of adaptation in virus-interacting proteins and longevity-associated pathways, linking two hallmarks of bat biology.

Jeff Coller, a pioneering RNA biologist, has spent the past year vehemently advocating for the lifesaving promise of research in the face of federal cuts

Plus d’un demi-million de Français ont signé la pétition appelant les députés à voter contre la proposition de loi sur les « formes renouvelées de l’antisémitisme », portée par la macroniste Caroline Yadan. À gauche, on espère que la mobilisation citoyenne influencera les élus lors de l’examen du texte la semaine prochaine.

Nature - Viral ribonucleoprotein–viral protein networks form pre-replication centres that nucleate viral factories and drive respiratory syncytial virus replication.

Author summary Bats are important to study as they are reservoirs for many viruses that can cause severe disease in humans. Notably, bats often show no clinical symptoms when infected with these virus...

L'Agence nationale de la recherche fête ses 20 ans dans un contexte de grandes tensions budgétaires. Sa présidente Claire Giry revient sur son bilan et décrypte les enjeux du moment.

Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...

La reconduction de Sébastien Lecornu à Matignon, cinq jours après sa démission, est stupéfiante parce qu’insensée. Le président de la République a définitivement renoncé à aligner ses décisions sur les aspirations populaires. Seule compte à présent la conservation du pouvoir.

Once they win elections, it's already too late.

Interferon-inducible Myxovirus resistance 1 (MX1) proteins are known to restrict influenza A virus (IAV) transcription/replication process. Herein,...

The genome carries information across generations, ensuring species survival. To preserve faithful transmission of genetic information, RNA-directed mechanisms safeguard the genome integrity in diver…

A resource of human RNA-protein associations is produced using a sequencing-based method.

A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.

This study reveals that ADAR1, an RNA-editing enzyme, fine-tunes immune responses in the placenta by preventing the accumulation of immunogenic double-stranded RNAs (dsRNAs) from interferon-stimulate...

Depuis quelques années, certains scientifiques explorent les liens inattendus entre les protéines humaines impliquées dans la défense de l’organisme et certains mécanismes immunitaires bactériens. C’e...

Bats are reservoirs for many viruses that frequently cause epidemics in humans and animals. It is thus critical to better understand their immune system and mechanisms of antiviral immunity. Despite a...

In mammalian cells, the presence of double-stranded RNA (dsRNA) in the cytoplasm is a danger signal indicative of viral infection. Cells establish and maintain an antiviral state via the production of...

There is no life without RNA or lipids. But could there be life with only RNA and lipids? The discovery that RNA can catalyse reactions in addition to encoding information opened new directions for...

Kellner et al. develop respiratory and intestinal organoids from Rousettus aegyptiacus to show elevated basal expression of interferon-ε (IFNε) and IFN-stimulated genes, along with robust, self-amplifying type III IFN responses that drive antiviral defense against zoonotic RNA viruses.