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Yehu Moran

@yehumoran.bsky.social
662 followers 597 following 112 posts

Evolutionary and molecular biology seasoned with ecology www.yehumoran.com Using mostly sea anemones and other cnidarians as my experimental model organisms. University Professor at HUJI and academic editor for EMBO Press. Opinions are my own.

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Yehu Moran @yehumoran.bsky.social · 25/08/2026
I love watching American Football 🏈, but I'm done watching the NFL. The finding that at least 1/4 former NFL players who died in 2016-21 had confirmed degenerative brain disease (CTE) crosses a line for me. I can't really enjoy a sport knowing that. www.nytimes.com/2026/08/25/u...
nytimes.com
At Least 1 in 4 NFL Players Gets CTE, Major New Study Finds
The actual prevalence, researchers said, may be much higher.
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Yehu Moran @yehumoran.bsky.social · 30/06/2026
Humbled and incredibly grateful to have been elected to the @embo.org Membership. Many thanks to everyone who has supported me throughout this journey, Mentors, Collaborators and Trainees alike. Special thanks to @odedrechavi.bsky.social for proposing my nomination. It is a tremendous honor. 🙏
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Yehu Moran @yehumoran.bsky.social · 26/06/2026
1/3 I'm so happy to see this one finally out! Ton Sharoni's years-long quest to characterize the antiviral role of a novel protein, CARDIB, is out in @natecoevo.nature.com The link appears in the following post. This protein is conserved in all anthozoans (sea anemones and 🪸) -->
static.klipy.com
Cardi B's Playful Dance Mood
ALT: Cardi B's Playful Dance Mood
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Yehu Moran @yehumoran.bsky.social · 01/05/2026
A very nice piece about our latest paper published in Open Biology by @royalsocietypublishing.org It's about how venom-producing stinging cells use chromatic modifications to determine their biochemical identity: royalsociety.org/blog/2026/04...
royalsociety.org
The secret life of stinging cells: chromatin regulation in sea anemones | Royal Society
This Open Biology study uncovers how specialised stinging cells used for prey capture and defence, are regulated at a deeper level than ever before.
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Yehu Moran @yehumoran.bsky.social · 16/03/2026
Today the EMBO Journal special issue on molecular ecology and evolution is finally published. It was a pleasure coordinating this collection together with @berndpulverer.bsky.social and many outstanding authors. Editorial: link.springer.com/article/10.1... Cover art by @munafomarzia.bsky.social
link.springer.com
EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal
The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...
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The EMBO Journal @embojournal.org · 18/02/2026
Read how @embopress.org is expanding its focus on molecular ecology and evolution as central underpinnings of functions/interactions/diversification of biological systems – by @yehumoran.bsky.social, @berndpulverer.bsky.social, and our new team of Editorial Advisors link.springer.com/article/10.1...
link.springer.com
EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal
The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...
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Yehu Moran @yehumoran.bsky.social · 18/02/2026
Editor perspective: finding 2–3 reviewers often means sending >20 invites. The peer-review system doesn’t run on magic. Worth remembering before clicking “decline” and later complaining about extremely slow reviews.
media.tenor.com
a man holding a cell phone with the word decline on his shirt
ALT: a man holding a cell phone with the word decline on his shirt
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Yehu Moran @yehumoran.bsky.social · 06/02/2026
#Tel_Aviv still has a few things going for it in February.
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Yehu Moran @yehumoran.bsky.social · 06/01/2026
1/3 🚨New paper from our lab!🔥 Most textbooks will tell you that invertebrates employ #RNAi as antiviral mechanism. Yet, do 🪸🪼 actually do it? Well, the answer is complicated. We show that in #Nematostella dsRNA induces RNAi 🧵 journals.plos.org/plosbiology/...
journals.plos.org
Characterization of RNA interference in the cnidarian Nematostella vectensis reveals partial target silencing but lack of small RNA amplification
RNA interference is an ancestral antiviral mechanism that degrades viral RNA through siRNAs, but its role in cnidarians has been unclear. This study shows that Nematostella vectensis likely possesses ...
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Yehu Moran @yehumoran.bsky.social · 25/11/2025
1/5 🚨🚨 preprint alert! 🚨🚨 I wish to introduce CARDIB, not the singer, but the protein. CARDIB=CARD Inhibitory Binding protein. In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals. www.biorxiv.org/content/10.1...
biorxiv.org
An ancient anthozoan protein reveals an alternative evolutionary path of antiviral signaling
How antiviral immunity first arose in animals is a central question in evolutionary biology. Using the sea anemone Nematostella vectensis, we identify CARDIB, a previously uncharacterized gene located...
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Yehu Moran @yehumoran.bsky.social · 13/11/2025
www.science.org/doi/10.1126/...
media.tenor.com
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ALT: a boy is riding on the back of a white dog with the words " it 's a never ending story " on the bottom
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Yehu Moran @yehumoran.bsky.social · 04/11/2025
Very happy and honored for being invited to give a keynote lecture at the 5th ISFSI conference in beautiful Tainan (and no, sea anemones are not fish or shellfish, but they are certainly marine invertebrates and have a fascinating immune system).
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Yehu Moran @yehumoran.bsky.social · 07/10/2025
1/3 🔥🚨 We have a new @biorxiv-evobio.bsky.social #preprint from our lab! Itamar Kozlovski, an excellent PhD student, established CUT&TAG in #Nematostella. He used this technique to map the transcriptional activation mark H3K27ac in two stinging cell populations www.biorxiv.org/cgi/content/...
biorxiv.org
Epigenomic and transcriptomic analyses reveal cnidocyte specialization in a sea anemone
Cnidarians, including corals, hydras, jellyfish, and sea anemones, possess specialized stinging cells called cnidocytes that function in prey capture and defense. These cells represent a striking evol...
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Yehu Moran @yehumoran.bsky.social · 03/10/2025
My first ever non-peer reviewed science-related piece. Together with Howard Wolinsky and Holger Breithaupt @embopress.org It's about how scientists critical of de-extinction are targeted by dark PR tactics: www.embopress.org/doi/full/10....
embopress.org
Scientists targeted by dark PR tactics: Several academic scientists critical of de-extinction projects have become the targets of anonymous smear articles and weaponized copyright infringement claims:...
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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Yehu Moran @yehumoran.bsky.social · 16/09/2025
There’s a reason no one remembers philosophers from Sparta: they had none. Athens valued ideas, Sparta only force. A 21st-century leader dreaming of a “super-Sparta” isn’t being visionary, he’s showing deeply flawed judgement. Oh, my country, what a train wreck you’ve become.
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Yehu Moran @yehumoran.bsky.social · 15/09/2025
I'm super proud of this guy!!! 👇
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Yehu Moran @yehumoran.bsky.social · 08/09/2025
Our paper about the interplay between heat stress, viral and antiviral response in sea anemones and #corals 🪸 is finally out! #OpenAccess Collaboration between my lab, Maoz Fine and @reefgenomics.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Heat Stress Drives Rapid Viral and Antiviral Innate Immunity Activation in Hexacorallia
The class Hexacorallia, encompassing stony corals and sea anemones, plays a critical role in marine ecosystems. Coral bleaching, the disruption of the symbiosis between stony corals and zooxanthellat...
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Yehu Moran @yehumoran.bsky.social · 07/09/2025
Very interesting results and a technical breakthrough in gene silencing in Trichoplax: Dissecting a peptidergic signaling pathway in Trichoplax adhaerens by gene silencing: Current Biology www.cell.com/current-biol...
cell.com
Dissecting a peptidergic signaling pathway in Trichoplax adhaerens by gene silencing
The simple marine animal Trichoplax adhaerens provides a unique window into early metazoan evolution. Li et al. develop an efficient RNAi-based gene knockdown method and uncover how neuropeptide-recep...
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Yehu Moran @yehumoran.bsky.social · 05/09/2025
A journal drags our review process for months over months. Even the final round after "accepted in principle" with some light text editing drags for weeks. Then the proofs come in, in the least convenient time possible, "we expect you to return your comments within 48 hours" 😖
media.tenor.com
two men are standing next to each other with blood on their faces . one of the men is wearing a plaid shirt .
ALT: two men are standing next to each other with blood on their faces . one of the men is wearing a plaid shirt .
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Luisa Cochella @lcochella.bsky.social · 03/09/2025
Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...
science.org
An ancient and essential miRNA family controls cellular interaction pathways in C. elegans
A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.
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Yehu Moran @yehumoran.bsky.social · 13/08/2025
We sent a paper to a "posh" journal. Waited for more than a month, Finally today the editor rejects the paper without external review. The logic is as follows: "I wanted 🍕, but you sent me a 🍔, and despite my expectations, there was no 🍕! I admit it's a fine 🍔, but where is the 🍕 I was expecting?"
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Yehu Moran @yehumoran.bsky.social · 12/07/2025
Achievement unlocked! Now, I can finally rest 🤪
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Yehu Moran @yehumoran.bsky.social · 12/07/2025
Hello, old friend. Didn't expect to meet you here... #Berlin #aquarium #Anemonia
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Yehu Moran @yehumoran.bsky.social · 21/06/2025
1/2 The new impact factor numbers are out. No sane person should use them as a proxy for anything, multiple organizations and institutes signed DORA, and still many people rely on them: I'll make it short and sweet: everything that carries "Nature" in its title went up. Sometimes crazily so -->
media.tenor.com
a man with a mustache says nature is amazing in a store
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Petr Svoboda @svobodalab.bsky.social · 18/06/2025
#TCTeAC ... what's more than organizing one conference? Two conferences! This one is more Day Science on biology of Argonaute proteins from prokaryotes to Metazoa. Great line up of invited speakers. Some special fun included!
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Julius Brennecke @juliusbrennecke.bsky.social · 17/06/2025
The fascinating work spearheaded by Kirsten Senti on the diversification and adaptation of endogenous retroviruses in the host gonad 'ecosystem'' is officially published.
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Yehu Moran @yehumoran.bsky.social · 12/06/2025
After more than 11 years, a long-due "postdocs reunion" with @xxxmichixxx.bsky.social at the @fmiscience.bsky.social Many thanks for the invitation, Michi! It was great meeting you and your colleagues and catching up on some cool science!
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Asaf Levy @asaflevylab.bsky.social · 11/06/2025
Our new paper is online in Genome Biology: "Plasmids, prophages, and defense systems are depleted from plant microbiota genomes" genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com
Plasmids, prophages, and defense systems are depleted from plant microbiota genomes - Genome Biology
Plant-associated bacteria significantly impact plant growth and health. Understanding how bacterial genomes adapt to plants can provide insights into their growth promotion and virulence functions. He...
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Yehu Moran @yehumoran.bsky.social · 01/06/2025
Peer Review can be of great value when done properly and awful when done badly. We waited 3.5 months for the decision, Reviewer #2: "Looking on the figures, I get the feeling their antibody is not specific". That's so insightful & informative! It was worth waiting just for this!!! 🙏🤪🤦😱
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Iana V. Kim @ianakim.bsky.social · 07/05/2025
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
nature.com
Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature
The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...
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Yehu Moran @yehumoran.bsky.social · 05/05/2025
I'm starting a short sabattical of 4 months at @embopress.org today! I hope we can achieve some good things for the molecular eco-evo community and science publishing during this time! #heidelberg
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Leah Houri-Zeevi @leahhouri.bsky.social · 20/04/2025
✨🦟✨HOW DO MOSQUITOES HAVE SEX? ✨🦟✨ Join us for a wild journey into hidden female control, rapidly evolving stimulation devices, fierce species competition, and DEADLY MOSQUITOES! www.biorxiv.org/content/10.1...
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Kaia Mattioli @kaiamattioli.bsky.social · 10/03/2025
born too late to get a two Western blot Nature paper, born too early to be a science TikTokker, born just in time to start a postdoc during a global pandemic and look for faculty positions during a historic hiring freeze
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Yehu Moran @yehumoran.bsky.social · 22/02/2025
Excellent work (as usual!) from the Genikhovich group! Highly recommended read.
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Vengamanaidu Modepalli @venky-vnm.bsky.social · 17/02/2025
Woohoo! Our image made the cover! 🎉 @jexpbiol.bsky.social The image captures photosymbiotic Anemonia viridis pointing it's tentacles towards the light. journals.biologists.com/jeb
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Yehu Moran @yehumoran.bsky.social · 12/02/2025
Happy Darwin day, everyone! Charles is 216 years old today. He is not here anymore, but his theory is still alive and well!
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Yehu Moran @yehumoran.bsky.social · 08/02/2025
Elon Musk trying to fix the grant overhead system in US academia is like a brain surgeon performing an operation on a patient using a sledgehammer... 🤦 BTW, the ones who are going to suffer the most from this are state universities, not the Ivy League... www.science.org/content/arti...
science.org
NIH slashes overhead payments for research, sparking outrage
Move to cut indirect cost rate to 15% could cost universities billions of dollars
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Yehu Moran @yehumoran.bsky.social · 01/02/2025
1/3 🎬 film review: I am very bad in working and sleeping on 🛩. So flying to Colorado and back on multiple Delta/Air France flights enabled me to fill quite some gap in recent movies (I love cinema but have no time). My impressions: Killers of the Flower Moon: Breathtaking and heartbreaking. 5⭐️ 🧵
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Yehu Moran @yehumoran.bsky.social · 28/01/2025
1/4 🚨 a brand new @biorxiv preprint from the lab! We charcterized both transcriptionally, morphologically and functionally (phagocytosis) immune cells from #Nematostella! We are convinced that our data supports the existence of such specialized cells! www.biorxiv.org/content/10.1... 🧵
biorxiv.org
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Yehu Moran @yehumoran.bsky.social · 27/01/2025
Transferring flights at Paris CDG as part of my long journey to @keystonesymposia.bsky.social on Non-coding #RNA. I'm very excited to attend this cool event for the first time! (and also visiting beautiful Colorado would be a 1st for me. Ummm, but temperatures look a bit scary! 🥶).
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Ella Preger 🎗️ @ella-pbn.bsky.social · 15/01/2025
It was a pleasure to host the awesome @yehumoran.bsky.social in our Developmental Genetics Club and learn about toxins and their role in modulating complex predation interactions!
Yehu Moran
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Yehu Moran @yehumoran.bsky.social · 13/01/2025
1/3 🚨 new preprint from our lab! For many years, it was unclear if and how RNAi contributes to antiviral immunity in Cnidaria. Sure, it is a key component in flies and nematodes, but these are protostomes. Yael Admoni finally tested this with help from 🧵 www.biorxiv.org/content/10.1...
biorxiv.org
Characterization of RNA interference in the model cnidarian Nematostella vectensis reveals partial target silencing but lack of small RNA amplification
RNA interference (RNAi) is an antiviral mechanism based on processing of viral double-stranded RNA (dsRNA) into short interfering RNAs (siRNAs) leading to dsRNA destruction. It is considered as an anc...
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Camille Curantz @camillectz.bsky.social · 08/01/2025
New insight on gonad morphogenesis ! Our new paper reveals how germ & somatic cells interact through TGF-Beta feedback loop to drive gonad morphogenesis in Hydractinia. Check out the full paper in Science Advances ! tinyurl.com/245rw699
tinyurl.com
A positive feedback loop between germ cells and gonads induces and maintains sexual reproduction in a cnidarian
Cnidarian germ cells secrete TGF-β to induce gonad development, and gonads induce germ cells by activating Tfap2 in stem cells.
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Yehu Moran @yehumoran.bsky.social · 03/01/2025
1/3 Our paper about miRNA target complementarity in Cnidaria is finally published in @emboreports.bsky.social This work was led by the talented Yael Admoni with help from Arie and Rubi in collaboration with the labs of @thecocodium.bsky.social and Michal Rabani www.embopress.org/doi/full/10....
embopress.org
miRNA-target complementarity in cnidarians resembles its counterpart in plants | EMBO reports
imageimagemiRNAs in plants and cnidarian animals operate similarly by binding their targets with nearly-full complementarity, in contrast to miRNAs in bilaterian animals that bind via a short seed-mat...
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Yehu Moran @yehumoran.bsky.social · 22/12/2024
1/3 I am very excited to tell you about our latest work where we looked not only into sea anemones but also 🪸 We find in #Nematostella that stress induces not immunity, but also viral replication, actually much faster than the immune response! 🧵 www.biorxiv.org/content/10.1...
biorxiv.org
Heat stress drives rapid viral and antiviral innate immunity activation in Hexacorallia
The cnidarian class Hexacorallia, encompassing stony corals and sea anemones, plays a critical role in marine ecosystems. Coral bleaching, the disruption of the symbiosis between stony corals and zoox...
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Yehu Moran @yehumoran.bsky.social · 13/12/2024
We went today to visit my parents, and this is what we came back to...
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Oded Rechavi @odedrechavi.bsky.social · 05/12/2024
Scared to share this after 10 freaking years of waiting, but here we go: We found that temperature *perception* can change the biology of the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance! www.biorxiv.org/content/10.1...
biorxiv.org
Perception of Temperature Even in the Absence of Actual Change is Sufficient to Drive Transgenerational Epigenetic Inheritance
Can processes occurring in one individuals nervous system influence the physiology of the descendants? Here we explored the provocative hypothesis that parents sensation or perception of environmental...
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Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · 06/12/2024
1/12 1. I’m very excited to share the first piece of my postdoc work! www.biorxiv.org/content/10.1...
biorxiv.org
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Yehu Moran @yehumoran.bsky.social · 04/12/2024
התראיינתי היום לשרון קנטור ב-"כאן תרבות" בנוגע לארס בעלי חיים 🐍🪸🪼🦂🕷 החל מ-1:37:10. מוזמנים להאזין! (My interview in Hebrew on the national radio about animal venom). www.kan.org.il/content/kan/...
kan.org.il
4.12.2024-שלושה שיודעים
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Yehu Moran @yehumoran.bsky.social · 01/12/2024
Anyone has experience with the Illumina NextSeq P4 50 bp kit (1.8 billion reads) for RNA-seq? Did it work well for your needs?
media.tenor.com
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