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Lea Gaucherand

@leagaucherand.bsky.social
271 followers 75 following 1 posts

Bats 🦇 Viruses 🦠 RNA 🧬 Immunity ♥️ Postdoc with Sébastien Pfeffer @CNRS Strasbourg studying bat antiviral immunity | PhD with Marta Gaglia @Tufts Boston studying influenza PA-X. she/her.

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Reposted by Lea Gaucherand
Lucie Etienne @lucievirevolte.bsky.social · 31/08/2026
Insights into longevity & virus-driven adaptation from Myotis bat genomes International & fantastic collab. with @psudmant.bsky.social @denard.bsky.social Labs ! Major credit to the 2 leading scientists: Juan Vazquez & @lauterbur.bsky.social now with their own labs! You 2 rock! (1/n)
nature.com
Insights into longevity and virus-driven adaptation from Myotis bat genomes - Nature
Comparative and functional analyses of Myotis bats uncover unique patterns of adaptation in virus-interacting proteins and longevity-associated pathways, linking two hallmarks of bat biology.
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Reposted by Lea Gaucherand
Lucie Etienne @lucievirevolte.bsky.social · 26/01/2026
📣 *Abstract submission by January 31st* "Host adaptations to viral infections” International Meeting May 10th-13th 2026 @cnrs.fr Station Biologique Roscoff, Brittany, France Register & Join us +amazing international speakers! #CNRS @cnrsbiologie.bsky.social #IRP www.insb.cnrs.fr/fr/evenement...
insb.cnrs.fr
Rapid host adaptations in response to viral infections
Viruses threaten all living organisms leading to molecular conflicts which have shaped hosts over evolutionary timescales. This meeting seeks to gather scientists from diverse disciplines including genomics, population genetics, innate immunology, virology, and beyond, to explore the evolution, diversity, molecular basis, and dynamics of these conflicts.
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Reposted by Lea Gaucherand
David Enard @denard.bsky.social · 23/10/2025
Come join us in beautiful Britanny, France in May 2026 for a workshop that I am organizing with @lucievirevolte.bsky.social and @psudmant.bsky.social on Rapid host adaptations to infections: sites.google.com/berkeley.edu...
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Lea Gaucherand @leagaucherand.bsky.social · 23/12/2025
Our latest paper on bat Dicer! 🦇 we show that Dicer antiviral RNAi activity is context-dependent also in bats 👩‍🔬 Specifically in Myotis myotis nasal epithelial cells, Dicer relocalizes to sites of viral replication upon alphavirus infection, which correlates with a proviral activity of Dicer 🦠
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Reposted by Lea Gaucherand
American Society for Virology @amersocvirology.bsky.social · 13/02/2025
Vaccines work! As measles cases have recently been reported in Alaska, Georgia, New York, Rhode Island and Texas, it's important to remember that prior to the introduction of the measles vaccine in 1963, measles killed 400-500 people and resulted in ~48,000 hospitalizations per year.
Graph showing that prior to 1963 when the measles vaccine was introduced, there were around 300,000-700,000 measles cases per year. Within a few years of the vaccine, the number of cases fell below 20,000/year. There were a blips where cases rose, but shortly after the second vaccine dose was recommended in 1989, annual cases have generally been well below 1,000 cases. In 2000, measles elimination was declared in the US. Now we have sporadic outbreaks that typically spread among unvaccinated people. Chart is from Center for American Progress and is based on CDC data on measles cases.
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Liz Neeley @lizneeley.bsky.social · 01/02/2025
Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences. Every Friday, I debrief you over a drink at buttondown.com/liminalcreat...
buttondown.com
Making Sense of It All
Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...
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Reposted by Lea Gaucherand
Charles Ornstein @charlesornstein.bsky.social · 01/02/2025
And more: Data on the CDC's website are being removed to comply with the Trump administration’s ongoing attempt to scrub federal agencies of any mention of gender, DEI, and accessibility, @katherinejwu.com reports. 9/x
theatlantic.com
CDC Data Are Disappearing
The agency has already removed scientific data from public view. More could follow.
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Reposted by Lea Gaucherand
Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 17/01/2025
📢Job alert We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
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Reposted by Lea Gaucherand
Petr Svoboda @svobodalab.bsky.social · 21/01/2025
1/n So, this is out in NAR, finally. The longest, the most expensive and the most challenging project in the lab. Sparked by controversy concerning mammalian antiviral RNAi and our identification of Dicer variant, which is sufficient to increase RNAi. doi.org/10.1093/nar/...
doi.org
Enhanced RNAi does not provide efficient innate antiviral immunity in mice
Abstract. In RNA interference (RNAi), long double-stranded RNA is cleaved by the Dicer endonuclease into small interfering RNAs (siRNAs), which guide degra
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