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Yad Ghavi-Helm

@yghavi.bsky.social
1.6K followers 707 following 66 posts

Researcher @CNRS, PI @igflyon.bsky.social, Scientific coordinator #spatialOMICs facility @Spatial_Cell_ID facility @ENSdeLyon #enhancer #transcription #development #3Dgenome #Drosophila

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Reposted by Yad Ghavi-Helm
Emília Santos @emiliapsantos.bsky.social · 14/07/2026
🎨 job alert 🐠 Come join us! We have two positions open! These are part of our @erc.europa.eu funded project on the mechanisms underpinning convergence of colour patterns in cichlid fishes! Closing date: 16th August. Postdoc: www.cam.ac.uk/jobs/researc... Technician: www.cam.ac.uk/jobs/researc...
static.klipy.com
Callipterus Cichlid Collecting Shell
ALT: Callipterus Cichlid Collecting Shell
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Yad Ghavi-Helm @yghavi.bsky.social · 13/07/2026
Due to a few last minute cancellations we have a limited number of places left. Please register before July 19th: spatial-cell-id.github.io/scid2026/reg...
spatial-cell-id.github.io
Registration & Fees
First Spatial-Cell-ID Summer Schools
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Yad Ghavi-Helm @yghavi.bsky.social · 13/07/2026
Having a great time with past, current and future PhD students! A bitter sweet feeling as we say farewell to @baalberti.bsky.social and @mmasoura.bsky.social who will soon join @halloulab.bsky.social and @nvastenhouw.bsky.social labs and welcome Emeline Gallo who was just awarded a PhD fellowship!
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Hadi Boukhatmi @muscleflylab.bsky.social · 02/07/2026
he early bird registration deadline for DrosoFrance 2026 has been extended until July 6th. Registration remains open until September 15th, but only a limited number of places are left. So if you're planning to join us for the french Fly meeting (Trégastel), don't wait too long!
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Yad Ghavi-Helm @yghavi.bsky.social · 02/06/2026
Extended deadline until June 14th. Registration is totally free of charge for CNRS employees (including PhDs and postdocs!) Special features: time for hiking around Aussois! Bring your own data to get advice from our expert bioinformaticians!
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Yad Ghavi-Helm @yghavi.bsky.social · 26/05/2026
Only few days left to apply! This event is relevant both for wet lab biologists who want to learn more about spatial OMICs and get initiated to data analysis and for bioinformaticians who want to learn about the latests developments in spatial OMICs.
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Yad Ghavi-Helm @yghavi.bsky.social · 18/05/2026
📢Join us for the Spatial-Cell-ID #spatialOMICs Summer School, September 13-18th 2026, at the Centre Paul-Langevin in Aussois, in the French Alps! You can find the full scientific program, our speakers, and the application form on our website: spatial-cell-id.github.io/scid2026/ Please share!
spatial-cell-id.github.io
SCID 2026
Using Spatial OMICs to uncover cell identity during developmental processes 13-18 September 2026 Aussois, France
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Yad Ghavi-Helm @yghavi.bsky.social · 18/02/2026
Don't miss this great opportunity!
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IGFL @igflyon.bsky.social · 17/02/2026
L’IGFL recrute un•e Professeur•e des Universités en biologie moléculaire (CNU 64), UCBL Lyon 1. Enseignement L2-M2 (Biochimie et Biologie Moléculaire) + projet en biologie moléculaire des eucaryotes au sein de l’IGFL. Détails: shorturl.at/K5Dno #Recrutement #BiologieMoleculaire
Annonce officielle de l’IGFL pour le recrutement du poste cité ci-dessus
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 16/01/2026
There is a special Current Opinion in Genetics & Development issue about genome architecture and expression and it looks great including reviews by @lennarthilbert.bsky.social @yghavi.bsky.social and @wbickmor.bsky.social www.sciencedirect.com/special-issu...
sciencedirect.com
Current Opinion in Genetics & Development | Genome Architecture and Expression (2026) | ScienceDirect.com by Elsevier
This collection summarizes key aspects of our current experimental and theoretical understanding of eukaryotic genome folding and its relationship with the molecular processes governing cell fate. Ove...
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Roland Le Borgne @leborgne.bsky.social · 06/01/2026
Happy New Year 2026! This year, Hadi Boukhatmi, Régis Giet and I are delighted to be organising the 36th French Droso Meeting in Brittany, from 5 to 8 October. A great line-up of speakers Mark the date in your diaries ! The meeting website containing all the details will be opening very soon.
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Yad Ghavi-Helm @yghavi.bsky.social · 10/11/2025
Congratulations to Dr @baalberti.bsky.social !! 🎉 And many thanks to his jury members @randersson.bsky.social @arnausebe.bsky.social @olivier-gandrillon.mastodon.social.ap.brid.gy Marie Sémon Anouck Necsulea and co-supervizor @paulvilloutreix.bsky.social
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Babis Galouzis @babisgalouzis.bsky.social · 18/10/2025
This is so cool! It’s also nice to see how careful genetic dissection of loci is still at the forefront of discovery!
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Daniel Ibrahim @danielibrahim.bsky.social · 16/10/2025
a really cool work! everyone check it out! congratulations 🎉👏🏽
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Christa Buecker @chribue.bsky.social · 16/10/2025
super cool to see this out! looking forward to now read the details! Congratulations, Yad and @mmasoura.bsky.social
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Yad Ghavi-Helm @yghavi.bsky.social · 16/10/2025
A must read! Check out @blanka-majchrzycka.bsky.social and @danielibrahim.bsky.social 's latest work
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Deevitha Balasubramanian @deevithab.bsky.social · 16/10/2025
Check out our new story on how broad enhancer inputs are restricted into tissue-specific gene expression 🧬 Hint: Promoter-proximal regions are the key!
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Daniel Ibrahim @danielibrahim.bsky.social · 16/10/2025
you must check out @yghavi.bsky.social and @mmasoura.bsky.social's story, who found a similar mechanism in Drosophila. it's so cool if two works align!! www.biorxiv.org/content/10.1...
biorxiv.org
Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
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Yad Ghavi-Helm @yghavi.bsky.social · 16/10/2025
Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by @mmasoura.bsky.social, to find out! www.biorxiv.org/content/10.1...
biorxiv.org
Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
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Yad Ghavi-Helm @yghavi.bsky.social · 25/09/2025
In the starting blocks for #EDRC2025! Come see our work at posters 100 and 155 and during the Gene expression in the 3D nuclear space workshop!
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Yad Ghavi-Helm @yghavi.bsky.social · 28/07/2025
Merci au @cnrsbiologie.bsky.social de mettre en avant notre travail! @baalberti.bsky.social @paulvilloutreix.bsky.social @igflyon.bsky.social @ensdelyon.bsky.social
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Yad Ghavi-Helm @yghavi.bsky.social · 23/07/2025
📢 We are recruiting! Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies. Please share and RT 🙏
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Baptiste Alberti @baalberti.bsky.social · 23/07/2025
🚨 Our paper is out! 🚨 Check how spatial-scERA can predict enhancer activity in a virtual Drosophila embryo. Very proud of this first step in the research world published in @narjournal.bsky.social Thanks to @yghavi.bsky.social, @paulvilloutreix.bsky.social and all the scientists who made it real!
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Yad Ghavi-Helm @yghavi.bsky.social · 23/07/2025
Now available in its final form @narjournal.bsky.social ! doi.org/10.1093/nar/... Find out how we can reconstruct enhancer activity in vivo in the Drosophila embryo using scRNAseq data and Optimal Transport.
doi.org
Spatial-scERA: a method for reconstructing spatial single-cell enhancer activity in multicellular organisms
Abstract. Enhancers play an essential role in developmental processes by regulating the spatiotemporal expression of genes. Characterizing their spatiotemp
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Bon Pote @bonpote.com · 19/07/2025
300 000 signatures dont plus de 200000 en moins de 48h ! L’objectif des 500 000 signatures est possible d’ici dimanche soir, afin d’obtenir un vrai débat à l’Assemblée nationale sur la loi Duplomb.
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Yad Ghavi-Helm @yghavi.bsky.social · 02/04/2025
Honored and extremely grateful to see our project in collaboration with @hilaryashe.bsky.social and @hilsawh.bsky.social awarded an #HFSPReseachGrant @hfspo.bsky.social Stay tuned for exciting job offers!
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Yad Ghavi-Helm @yghavi.bsky.social · 23/01/2025
Thanks @evodevogenomeub.bsky.social @criscanestro.bsky.social for having us and showing us all the secrets of beautiful Oikopleura!! 😍
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Yad Ghavi-Helm @yghavi.bsky.social · 21/01/2025
Lovely day at @biom-banyuls.bsky.social So much exciting science on cool marine species!
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Paul Villoutreix @paulvilloutreix.bsky.social · 12/12/2024
Poster #5 is a collaboration with @yghavi.bsky.social led by Baptiste Alberti where we propose a method for reconstructing of the spatial single-cell enhancer activity in a multicellular organism www.biorxiv.org/content/10.1...
biorxiv.org
Spatial reconstruction of single-cell enhancer activity in a multicellular organism
Enhancers play an essential role in developmental processes by orchestrating the spatial and temporal regulation of gene expression. However, mapping the location of these regulatory elements in the g...
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Yad Ghavi-Helm @yghavi.bsky.social · 18/11/2024
On my way to Heidelberg @EMBL #EMBLOmics to present our work. Looking forward!!!
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Yad Ghavi-Helm @yghavi.bsky.social · 18/11/2024
🚨Preprint alert! tinyurl.com/2zkmynsd Did you ever dream of reconstruction #spatial single-cell #enhancer activity in a multicellular organism using massively parallel enhancer-reporter assays? Then Spatial-scERA is the method for you! #spatialOMICs
tinyurl.com
Spatial reconstruction of single-cell enhancer activity in a multicellular organism
Enhancers play an essential role in developmental processes by orchestrating the spatial and temporal regulation of gene expression. However, mapping the location of these regulatory elements in the g...
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