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Miguel Branco

@brancolab.bsky.social
1.9K followers 1.1K following 164 posts

Transposons and epigenetics. brancolaboratory.com

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Reposted by Miguel Branco
Maya Voichek @mayavoichek.bsky.social · 24/09/2026
Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)
AI-generated illustration of the soma-to-germline transmission of retrotransposons described in our work
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Leonid Schneider @forbetterscience.bsky.social · 22/09/2026
A Book That Will Never Be Read forbetterscience.com/2026/09/22/a...
forbetterscience.com
A Book That Will Never Be Read
“I cannot shake the feeling that we find ourselves in a publisher-papermill complex, powered largely by public funding. ” – Michal Wojcik
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Nature Reviews Genetics @natrevgenet.nature.com · 17/09/2026
New online! Gene regulatory mechanisms downstream of DNA methylation
dlvr.it
Gene regulatory mechanisms downstream of DNA methylation
Nature Reviews Genetics, Published online: 17 September 2026; doi:10.1038/s41576-026-01008-3In this Review, Buckley et al. discuss how DNA methylation is interpreted in mammals and plants, focusing on the reader proteins and transcription factors that bind to methylated DNA and the downstream mechanisms by which they regulate transcriptional and epigenetic states.
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Dr Radu Zabet @raduzabet.bsky.social · 11/09/2026
Happy to share the peer-reviewed version of this manuscript now published in Bioinformatics Journal. Briefly, we developed HiCPotts, a novel method to better detect 3D DNA contacts from HiC/microC data. doi.org/10.1093/bioi... bioconductor.org/packages/HiC... For a summary, see original post.
doi.org
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Antoine Molaro @antoinemolaro.bsky.social · 09/09/2026
Hello World ! Reminder about our open postdoc position 🧪🧬 Reviewing applications until October - get in touch to know more about what's hot in the lab these days ! Application details in the post below 👇👇 #EvoEpi #MolaroLab #watwat #ERC
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Johann Confais @johannconfais.bsky.social · 07/09/2026
📢 We (@clementgoubert.bsky.social @ritarebollo.bsky.social) are happy to share our new mini-review: “Computational Tools and Lessons Learned from Annotating Transposable Elements in Insect Genomes” doi.org/10.1016/j.co... #TransposableElements #TEannotation #InsectGenomics #Bioinformatics #TEsky 🧵👇
doi.org
Redirecting
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 03/09/2026
wait, wait, what ????? protein-coding chimeric mRNAs 🤯 www.nature.com/articles/s41...
nature.com
Functional chimeric mRNAs encode proteins in mammalian immunity - Nature
Inflammation induces interchromosomal DNA interactions that bring parent genes into close proximity, facilitating the formation of chimeric mRNAs that encode physiologically relevant, functional prote...
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Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Geula Hanin @geula.bsky.social · 07/08/2026
🚨 We're hiring! Join the Hanin Lab @ Cambridge as a Research Assistant/In-vivo Scientist. We're looking for someone with molecular and in-vivo experience to study how lactation & early-life nutrition shape lifelong health. Apply by 16 Aug: www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Assistant (In-vivo Scientist) (Fixed Term)
The Hanin Lab, based in the Department of Physiology, Development and Neuroscience at the University of Cambridge, investigates the molecular basis of lactation and early nutrition to understand how m...
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Stefan Schoenfelder @stefanschoenfelder.bsky.social · 07/08/2026
Very happy to see this story finally out in @natbiotech.nature.com: www.nature.com/articles/s41... Fantastic collaboration with @lancasterlab.bsky.social on how to identify and ‘fix’ differentiation-compromised human pluripotent stem cells. @babrahaminst.bsky.social @mrclmb.ac.uk 🧵 below
nature.com
Reversible epiblast regionalization determines differentiation potential of human pluripotent stem cells - Nature Biotechnology
The differentiation variability of human pluripotent stem cell lines is diagnosed and corrected.
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Niakan Lab @niakanlab.bsky.social · 04/08/2026
We have a postdoc position available in the lab and would like to spread the word. Please apply if you are interested! www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Associate (Fixed Term)
We seek a highly motivated Postdoctoral Research Associate to join the laboratory of Professor Kathy Niakan. We are based in the Loke Centre for Trophoblast Research (LCTR), in the Department of Physi...
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Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 13/07/2026
Big conferences are impressive. But how often do you actually meet someone there? 🤔 The Epigenetics Meeting was created differently. We have a great line-up of speakers with exciting research topics, ample time for discussion, and very familiar setting. Join us now: events.ie-freiburg.mpg.de
A dark blue poster with yellow and white text announces the Max Planck Freiburg 8th Epigenetics Meeting, scheduled for 2–4 December 2026 at the MPI of Immunobiology & Epigenetics. The top section features a stylized DNA strand in yellow and blue. The main content is organized in columns, listing speakers, keynote, registration details, and the scientific organizer. Speaker names and affiliations are grouped under 'Speakers' and 'Keynote.' The registration start date is 1 April 2026, with a deadline of 1 September 2026. The bottom left corner contains a QR code and a web address. The background includes subtle DNA helix graphics.
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Claudia Köhler @claudiakohler11.bsky.social · 01/07/2026
Our lab @mpi-mp-potsdam.bsky.social is hiring two postdoctoral researchers to join our ERC-funded GRAFT project on mobile small RNAs in plants. 🔗 Details: jobs.mpimp-golm.mpg.de/jobposting/b... 📅 Deadline: July 31, 2026 Please share!
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The Royal Society @royalsociety.org · 30/06/2026
We are very happy to announce the six titles shortlisted for the Royal Society Trivedi Science Book Prize 2026. From health misinformation to the fishing industry, these mind-growing reads represent the best of science writing from the past year. #SciBooks bit.ly/4vgp5Zm
bit.ly
Shortlist unveiled for Royal Society Trivedi Science Book Prize 2026 | Royal Society
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Job Dekker @jobdekker.bsky.social · 01/07/2026
Frank Grosveld has been a giant in the field of long-range gene regulation. Inspirational to me and I am sure for many others. Rest in peace.
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Clément Goubert @clementgoubert.bsky.social · 25/06/2026
Major development in the #Transposon world! Repbase is joining the Dfam project and becomes open-access! link.springer.com/article/10.1...
link.springer.com
Unifying Repbase and Dfam: a new open foundation for transposable element research - Mobile DNA
Repbase and Dfam, the two foundational resources for transposable element annotation, are being unified into a single, fully open access framework, with Repbase released under CC-0 and its core curati...
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Helen Zenner @helenzsci.bsky.social · 25/06/2026
The 1% from QED has made for an interesting debate here! My initial thoughts - Highlighting research esp preprints is a good thing - Lists are good, rankings maybe not so much - What does a ranking even mean? - Can the LLM read the figures? Isn’t looking at the data how we evaluate research!?
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Miguel Branco @brancolab.bsky.social · 23/06/2026
open.substack.com
Opinion: I Was Not Allowed To Type Prompts Into ChatGPT During My Chalk Talk And This Is Discrimination
By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University
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Ted Pavlic (he/him/his) @tedpavlic.bsky.social · 22/06/2026
The #Rstats development team receives some well-deserved recognition! "As part of the prize, the R team - who have thus-far been unpaid [for R work] - will get to split $1m (£755,000) between them." "The Oxford professor making sense of the world's data" www.bbc.com/news/article...
bbc.com
Prof Brian Ripley on developing R to manage the world's data
Prof Brian Ripley has spent the past three decades working on a computer software that analyses data.
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Karen Hao @karenhao.bsky.social · 20/05/2026
On the one-year anniversary of EMPIRE OF AI, I am so, so excited to announce The AI Resist List, a new project that documents examples of resistance to the AI empires around the world 😍 airesistlist.org
The gorgeous AI Resist List homepage
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Rafal Mostowy @rafalmostowy.bsky.social · 04/05/2026
Polish phage science meets Polish visual storytelling 🇵🇱🦠 To celebrate our last paper, we collaborated with an artist who previously worked on The Witcher 3 — to create a comic about phages and why understanding them matters in the fight against antibiotic-resistant bacteria. Comic below 👇
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Simon Hammann @simonhammann.bsky.social · 20/04/2026
Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
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Miguel Branco @brancolab.bsky.social · 23/04/2026
scRNA-seq has partly ruined murmurations for me...
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Rakyan Lab @rakyanlab.bsky.social · 10/04/2026
Super happy to share the published version of our study: “Germline sequence variation within the ribosomal DNA is associated with human complex traits” in Cell Genomics www.cell.com/cell-genomic...!
cell.com
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Sasha Gusev @sashagusevposts.bsky.social · 01/04/2026
Monthly median Received to Accepted time (days) at Nature Genetics
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Charlène Boumendil (She/Her) @charleneboumendil.bsky.social · 20/03/2026
We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...
igh.cnrs.fr
Join IGH as Group Leader - IGH
The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...
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Mark A. Hanson @hansonmark.bsky.social · 15/03/2026
I appreciate someone took the time to write this. I profoundly disagree with their view, but if I take the spirit of what they're saying as a good faith attempt to raise a mental issue, there's at least a conversation to be had. Let's have it 1/🧵 www.science.org/content/arti... #AcademicChatter
science.org
Why I may ‘hire’ AI instead of a graduate student
“It can competently perform a lot of the work I need immediately,” this professor writes
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Maxim Greenberg @maxvcg.bsky.social · 09/03/2026
Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/
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Sara R Heras @herassr.bsky.social · 05/03/2026
Graphical abstract from our new paper in Nucleic Acids Research with @saramaciasrna.bsky.social 🧬 DGCR8 prevents accumulation of endogenous dsRNA derived from Alu elements within mRNAs, avoiding aberrant activation of the interferon response. academic.oup.com/nar/article/...
academic.oup.com
Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8
Abstract. The type I interferon (IFN) response is the main innate immune pathway against viruses in mammals. This pathway must be tightly regulated to prev
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Reposted by Miguel Branco
Hadley Wickham @hadley.nz · 05/03/2026
These captchas just keep getting harder #rstats
A digital CAPTCHA verification window titled "Select all squares with PIPES" against a plain white background. The window contains a 3×3 grid of numbered squares, mixing literal hardware, smoking pipes, and programming syntax.
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Dr Radu Zabet @raduzabet.bsky.social · 05/03/2026
Excited to share our latest publication on interindividual variation of DNA methylation in human whole blood, spearheaded by the amazing Olivia Grant and co-led with @leo-schalkwyk.bsky.social and Meena Kumari. link.springer.com/article/10.1...
link.springer.com
Systematic investigation of interindividual variation of DNA methylation in human whole blood - Genome Biology
Background Interindividual genetic variability is well characterised, but we still lack a complete catalogue of loci displaying variable and stable epigenetic patterns. Results Here, we report a catal...
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QMUL Centre for Epigenetics @qmulepigenetics.bsky.social · 04/03/2026
We're excited to announced that our 2nd Annual QMUL Centre for Epigenetics Conference is happening on June 18th, 2026 at Mile End! To find out more and book your ticket, please follow this link: www.qmul.ac.uk/epigenetics/... The deadline to book your tickets is Monday, June 8th 2026.
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Joanna W Jachowicz @jjachowicz.bsky.social · 02/03/2026
If you want to explore ncRNA dynamics during mammalian development, love microscopy, and are not afaraid of transposons biology, apply‼️ We are looking for a postdoc to join our team at @imbavienna.bsky.social More details 👇🏻
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Miguel Branco @brancolab.bsky.social · 26/02/2026
👇👇👇👇👇👇👇👇👇👇
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 25/02/2026
We are hiring! Join the Jachowicz lab as a postdoctoral researcher. The project focuses on understanding the dynamics of ncRNAs using high-resolution and single-molecule microscopy approaches. Link below 👇
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Hao Yin @haoyin.bsky.social · 24/02/2026
Transposable element regulation as a therapeutic target for #Aging activating Suv39h1 inhibiting KDM4A inhibiting TET CRISPRi/a to program TEs in the genome #OpenBiol 2026 royalsocietypublishing.org/rsob/article...
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Courtney Hanna @cwhanna.bsky.social · 20/02/2026
This will be a great meeting! Don't forget to register!
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Max Haase @maxhaase.bsky.social · 18/02/2026
Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14
nature.com
Ancient co-option of LTR retrotransposons as yeast centromeres - Nature
Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...
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Dr Radu Zabet @raduzabet.bsky.social · 17/02/2026
Hot off the press, our latest publication on the functional role of gene body methylation (gBM). academic.oup.com/nar/article/... Work spearheaded by Jakub Zastapilo with help from @robynemm.bsky.social and Liudmila Mikheeva and co-led by Marco Catoni and @ubechtold.bsky.social 1/3
academic.oup.com
Gene body methylation buffers noise in gene expression in plants
Abstract. Non-genetic variability in gene expression is an inevitable consequence of the stochastic nature of processes driving transcription and translati
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Komal Yasmin @komal-yasmin.bsky.social · 13/02/2026
Are you a DNMT3 enthusiast wondering how they achieve specificity at CpG islands during development? And why is DNMT3B specifically required for methylation on the inactive X? We set out to dissect the mechanism, now published in Genes & Development genesdev.cshlp.org/content/earl... [1/12]
genesdev.cshlp.org
Chromatin binding and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
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Susan Gasser @susanmgasser.bsky.social · 11/02/2026
Let’s celebrate women and girls in scientific research! Often underestimated, women drive research in biomedical sciences both intellectually and at the bench. Research should be a “gender-blind” endeavor, but rarely is. Stop bigotry ! Stop unconscious bias ! Go women & girls!
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Miguel Branco @brancolab.bsky.social · 11/02/2026
🤯
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Geula Hanin @geula.bsky.social · 09/02/2026
🎉 After a very long one (appropriately…), I’m excited to share work revealing an unexpected role for the epigenetic regulator ZFP57 - linking development, lactation, milk composition and lifelong health. Check it out: www.nature.com/articles/s41... #MammaryGlandBiology #DOHaD
nature.com
ZFP57 is a regulator of postnatal growth and life-long health - Nature Communications
Lactation is essential, but its genetic and epigenetic regulation is poorly understood. Here, Hanin et al. show that ZFP57 has an imprinting-independent role in controlling postnatal nutritional suppo...
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Miguel Branco @brancolab.bsky.social · 06/02/2026
Congrats @retrogenomics.bsky.social! Richly deserved.
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Marnie Blewitt @marnieblewitt.bsky.social · 06/02/2026
Our new preprint on SMCHD1! We’ve shown SMCHD1’s ATPase activity is critical for function in vivo, and excitingly a new DNA binding domain neighbouring the ATPase domain activates the enzymatic function, which is important for normal chromatin binding. urldefense.com/v3/__https:/...
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Sylvia Erhardt @erhardtlab.bsky.social · 03/02/2026
🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!
Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.
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Genetics Society UK @gensocuk.bsky.social · 03/02/2026
Registrations are now OPEN! Join us in Newcastle for the “RNA in Physiology and Disease” conference, an international meeting bringing together world-leading RNA biologists and emerging researchers. Early bird deadline: 1 May Abstract deadline: 30 June Register now: genetics.org.uk/events/rna-i...
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Miguel Branco @brancolab.bsky.social · 02/02/2026
New preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.
biorxiv.org
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