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Richelle Sepulveda

@richellesepulveda.bsky.social
3.2K followers 1.5K following 3.6K posts

Long Covid, MECFS, ADHD, etc. Patient-led research is my jam. A bit obsessed with GIP.

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Reposted by Richelle Sepulveda
Anna Holmes @annabookwriter.bsky.social · 4h
Some things I wish I had known when I was a new writer: Being accepted by traditional publishers has less to do with skill than whether they think they can sell it. Just because publishers aren’t ready for a story doesn’t mean readers aren’t. Writing the book is the easy part. 🧵
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Anna Holmes @annabookwriter.bsky.social · 4h
Self publishing is not easier than trad publishing. It’s also not for vain people. You aren’t, so you’ll get frustrated by people insinuating your books are vanity projects. You don’t want a billion fans. You want like five people who deeply understand what you wrote, and even one is a blessing.
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jackheathwriter 📚 @jackheathwriter.bsky.social · 23h
And this one, from 1975:
The Rape of Mr. Smith 
In the following situation, a holdup victim is asked questions by a lawyer. 
“Mr. Smith, you were held up at gunpoint on the corner of First and Main?” 
“Yes” 
“Did you struggle with the robber?” 
“No.” 
“Why not?” 
“He was armed.” 
“Then you made a conscious decision to comply with his demands rather than resist?” 
“Yes.” 
“Did you scream? Cry out?” 
“No, I was afraid.” 
“I see. Have you ever been held up before?” 
“No.” 
“Have you ever GIVEN money away?” 
“Yes, of course.” 
“And you did so willingly?” 
“What are you getting at?” 
“Well, let’s put it like this, Mr. Smith. You’ve given money away in the past. In fact, you have quite a reputation for 
philanthropy. How can we be sure that you weren’t CONTRIVING to have your money taken from you by force?” 
“Listen, if I wanted –“ 
“Never mind. What time did this holdup take place, Mr. Smith?” 
“About 11:00 P.M..” 
“You were out on the street at 11:00 P.M.? Doing what?” 
“Just walking.” 
“Just walking? You know that it’s dangerous being out on the street that late at night. Weren’t you aware that 
you could have been held up?” 
“I hadn’t thought about it.” 
“What were you wearing at the time, Mr. Smith?” 
“Let’s see … a suit. Yes, a suit.” 
“An EXPENSIVE suit?” 
“Well – yes. I’m a successful lawyer, you know.” 
“In other words, Mr. Smith, you were walking around the streets late at night in a suit that practically advertised 
the fact that you might be good target for some easy money, isn’t that so? I mean, if we didn’t know better, Mr. 
Smith, we might even think that you were ASKING for this to happen, mightn’t we?”
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It's ME(Jaime) @exceedhergrasp1.bsky.social · 9h
Babe 😭 (Genuinely, read this right now. It's excellent.)
To be fair, I’m not doing so great with men. I told my most recent date that I was working on a novella. “Because you’re Mexican?” he asked. I asked what he meant. “Isn’t a novella a Mexican novel?” Before him was the guy who confessed over drinks that he didn’t “believe in Helen Keller,” because there was “no way she actually flew that plane.” I asked if he meant Amelia Earhart. “Who?” I slept with both of them.
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Charlie Warzel @cwarzel.bsky.social · 12h
There is a moment at the very very end of Abdul El-Sayed's podcast with Ezra Klein (book recommendation section) where he talks about the idea of "speaking truth to pain" and this will be staying with me for an extremely long time. www.nytimes.com/2026/09/25/o...
But there’s also something about truth to pain. We talk a lot about truth to power, but I think it’s actually a lot harder to speak truth to pain. I say that as someone who went to medical school, realizing that in a lot of our politics right now, we’ve got to get a lot better at speaking truth to pain if we’re going to get through some of these challenges that we have.

What does “truth to pain” mean?

It’s one thing to look power in the eye and say: You’re wrong about this. But there’s a way in which pain is very difficult to reason with. Because when somebody is in their pain, they’re in their trauma. They see that pain, and they may not see what’s causing it.

I remember just very explicitly being in a trauma ward with a gunshot wound patient and watching this big guy with his hand on his gunshot wound. All the folks are trying to pull his hand off his pain, that point of his gunshot wound, this clear vulnerability.

And this emergency room doctor had the presence of mind to be like: Everyone, stop. And she looks him in the eyes, and she’s like: I get that really hurts, and I’m so sorry that you’re here. You don’t want to be here. We don’t want you to be here. But if you don’t let us fix this, you could die. So I’m going to take your hand, and I’m going to move it off, OK? Because I need to get there so that you can live.

She was speaking truth to pain. He understands he’s at the hospital, he needs care, but he also doesn’t want anybody to touch the wound. Which is a natural thing. And I think it is a really great metaphor for how we think about a lot of these challenges we talked about today.
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Xodanix3 @xodanix3.bsky.social · 13h
Continuing to share cuz needs don't stop 💸💕 #helpsky
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It's ME(Jaime) @exceedhergrasp1.bsky.social · 16h
If you see this, post a vampire that isn't Dracula.
Spike, from Buffy the Vampire Slayer, has pale skin and bleach-blonde, slicked-back hair with dark brows.  He's wearing a black tee shirt and is tied to a fluffy red chair at the arms and waist (very loosely).  He's ducking his head and looking up from under his brows sardonically, and giving the camera a two-fingered salute.  It looks like at one point he was wearing black nailpolish, but it's mostly picked away.
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Shiv Ramdas Mens Rice Activist @nameshiv.bsky.social · 17h
I'm kinda fully over that "the British conquered the world for spices and don't use any of them" joke because for one, you cannot recycle material for 5 straight generations and get a laugh worth a damn but also because in order to make it you have to agree with Tommy Robinson about who is British
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Pavel @spavel.bsky.social · 30/09/2026
Three Rings for Erica under the sky, Seven for Rita in their halls of stone, Nine for Monica doomed to die, One for Tina on his dark throne In the Land of Mordor where the Shadows lie. One Ring to rule them all, here I am A little bit of you marks the Fall of Man
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Em, midly @lefttheprairie.bsky.social · 29/09/2026
So excited to set up a little rodent planned parenthood in my alley
WE’RE PUTTING RATS ON BIRTH CONTROL
Yes, you read that right
AND WE NEED YOUR HELP.
Join NRC to learn about a new approach to reducing our neighborhood rat population-and sign up to become a community volunteer.
COMLUS LEO + VOLUNEER SESSON
SEPTEMBER 29 • 6PM
NRC OFFICE • 3403 W LAWRENCE, STE 301
NORTH RIVER
Albany Park & Irving Park
COMMISSION
Special Service Area 60
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GOLIKEHELLMACHINE @golikehellmachine.com · 30/09/2026
judging just by what i have seen in brief snaps on the TL today, republicans are catastrophically unprepared for what’s going to be coming at them
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Kristin Meekes @kmeekes.bsky.social · 29/09/2026
The pandemic should have led to clean indoor air, treatments for long covid and related illnesses, next gen vaccines, normalization of masking, mandatory respiratory protection in healthcare, sick leave, and a paradigm shift around what infections do to people
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Bree (half of Kit Rocha) @mostlybree.kitrocha.com · 29/09/2026
okay so I got this because of the glam kitchen lady who was making guacamole with it but it turns out that now that I have a garden this is my favorite tool in my kitchen and I use it every day idek where the other parts are I just dice everything all the time. LOL link.amazon/B01ep2Kou
the fullstar chop wizard box that basically  just has a place you put food on top of a grid of cutting blades and then you smash down the top and it dices it
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John Scalzi @scalzi.com · 29/09/2026
A thing I learned not too long ago is that when an LLM selects a token that leads it down an incorrect path (factually), it has no way to back up, or even know that it should back up, it's just on to the next likely bit. Literally every LLM is just posting their way through it. What an image.
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botanical barbie @hemingwaymuse.bsky.social · 29/09/2026
We are doing a crock pot meal drive including crock pots but are hitting a wall when it comes to crock pot donations would anyone here be interested in sponsoring some? If yes I can add some to our wishlist, I'm seeing some that start around $40 for 7qt, more for 10qt
CROCKTOBER DRIVE
Bean & Ladle is teaming up with the Cordell Blessing Box to help local families put warm, easy dinners on the table this October!
We're putting together Crocktober bundles. Each family will receive a crock pot, a box of slow cooker liners, and meals I'll prep in gallon freezer bags for them to cook at home.
Our first goal is to help 20 families with a crockpot and 10 meals and keep providing meals all winter!
Here's how you can help:
Donate a new or gently used, working crock pot
with its lid
Donate unopened slow cooker liners or gallon
freezer bags
• Donate ingredients from our meal supply list, coming soon
Give money or a grocery gift card to help
purchase meat and other ingredients
If you'd like to donate or help sponsor a bundle, send us a message. If your family could use one, please message us privately, too.
Together with the Cordell Blessing Box, let's take care of our neighbors-one crock pot meal at a time.
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Assigned Media @assignedmedia.org · 29/09/2026
Democrats seem headed for big wins, but one avenue for self-sabotage would be adopting R's framing on trans rights. @billiejsweeney.bsky.social spoke with insiders incl Lanae Erikson of Third Way and Rep. Sarah McBride for this substanial piece of new reporting. assignedmedia.org/breaking-new...
assignedmedia.org
Democrats Lose by Punching Down on Trans Issues, Strategists Say - Assigned Media
Insiders, including at centrist think tank Third Way, are cautioning Democratic candidates against echoing Republican talking points on trans rights.
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Micah @rincewind.run · 29/09/2026
third way figured out dems should stop attacking trans people? third way?!
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Micah @rincewind.run · 29/09/2026
that said, while I think having a large following means you are responsible for where you point the Eye of Sauron, it does not mean that people with a small following should be allowed to say whatever out of pocket shit they want to you and then play "I'm just a little birthday boy" if you respond
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Richelle Sepulveda @richellesepulveda.bsky.social · 29/09/2026
This is part of why there's such dismantling and disregard of academia right now. These people have such a visceral reaction to being wrong and instead of learning more so they aren't speaking of topics they know nothing about, they will attack those who DO know more.
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"Online Rent-a-Sage" Bret Devereaux @bretdevereaux.bsky.social · 29/09/2026
The angry response is what comes out so clearly to me - normal people, if they're caught out mistaking the Hawks for the Hawkeyes are going to be embarrassed and apologetic, but Schmitt's response is volcanic 'how dare you' anger. Just manifest low character, frankly.
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Captain Awkward @captainawkward.bsky.social · 29/09/2026
Even someone who absolutely meant to be an asshole is capable of reading the room (the room where you pushed back this time!) and determining that this is a tough crowd. They may still be a jerk in their hearts forever, but they might think twice about how they act around you.
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Ryan Nanni @celebrityhottub.bsky.social · 29/09/2026
listen i'm not gonna link to it but "stay at home parents would simply have no use for universal daycare" is some of the most "oh you've never actually talked to anyone" shit i've ever heard
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Annalee @flowerhorne.com · 29/09/2026
Ours is a world where "of course you show up if the neighbor is hosting a wake even if you never met the deceased" people live right next to "no you don't barge in on someone's grief" people and where both would feel certain that theirs was the respectful and appropriate choice
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Nicole Bedera @nbedera.bsky.social · 29/09/2026
Studies dating back to the 80s have found that men are not just “confused” about consent. They just don’t prioritize consent over things like power, domination, and sexual gratification. Men participating in a gang rape know they don’t have the victim’s consent.
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Colette Delawalla, PhD @cdelawalla.bsky.social · 29/09/2026
Knowledge is NOT politically neutral. The scientific method is a tool for deriving knowledge. So why then, are we telling the arbiters of the scientific method and developers of knowledge to be politically neutral? Are scientists supposed to forsake knowledge for politics sake?
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mal @malorienilson.com · 28/09/2026
Hello, Idaho friends who are concerned about the recently proposed data center on public land outside of Boise! It would be so helpful if you can plan to attend the public hearing (virtually or in-person, as you are able) to give comment. Please share! www.nwcouncil.org/meeting/publ...
nwcouncil.org
Public hearing on draft Ninth Power Plan (Idaho Falls) | Northwest Power and Conservation Council
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Robin Bradford @tuphlos.bsky.social · 29/09/2026
That was some version! The anthem works better for me as instrumental. And they played the heck out of that.
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Anna Holmes @annabookwriter.bsky.social · 29/09/2026
I’m disabled and an assault survivor and I see allegations of fakery for both the same way. The public attention, stigma, and violence that follow us around is far more intense than any benefit one might illicitly gain. Nobody would ever invite this level of scrutiny and judgment without cause.
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Reuters @reuters.com · 29/09/2026
Scientists studying the strongest genetic ‌risk factor for Alzheimer's disease say they have new clues to how it works and how its damaging effects on the brain could potentially be reversed. 📩 Reuters Health Rounds explains: reut.rs/4e3rtMZ
reut.rs
NEWSLETTER: Genetic discovery yields clues toward reversal of Alzheimer's brain damage
Today we highlight a discovery with potentially important implications for future Alzheimer's research and treatments. We also report on an experimental Gilead therapy showing great promise ​against a...
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s. e. smith @sesmith.lol · 28/09/2026
Given both the literal and figurative climate, the number of counties banning renewable energy generation is wild!
dailyyonder.com
A Rural Idaho County Banned Renewables. It’s Having Second Thoughts | The Daily Yonder
This article was co-published with Canary Media, a newsroom covering clean energy. Jeff Hough did not pull any punches. What his fellow Republican county
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Richelle Sepulveda @richellesepulveda.bsky.social · 28/09/2026
He's at the dental surgeon now. Should be a couple of hours. I wonder how much hardware he will have while he heals? I guess we will see soon!
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Richelle Sepulveda @richellesepulveda.bsky.social · 28/09/2026
Kitty is at the dental surgeon now. They were able to get him in this morning, and the projected cost is not near as much as I feared it would be. Surgeon says he seems pretty well hydrated, so he's been lapping water in very small doses when I'm not looking, apparently.
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It's ME(Jaime) @exceedhergrasp1.bsky.social · 26/09/2026
I'm working on a project to educate emergency doctors right now. There's stuff to do and use! Even simple things like saline are helpful for an orthostatic crisis, for example
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Xalavier Nelson Jr. @writnelson.bsky.social · 28/09/2026
WE'RE MAKING A SHELVING SIM WHERE YOU USE THE DEWEY DECIMAL SYSTEM IN A LIBRARY THAT'S HAUNTED AS FUCK BECAUSE A BILLIONAIRE WAS STUFFING CORPSES IN THE WALLS TO GENTRIFY HIS CITY WISHLIST "SOMETHING IS WRONG WITH THE LIBRARY" TODAY store.steampowered.com/app/3971340/...
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Tom Kindlon @tomkindlon.bsky.social · 28/09/2026
The Severe & Very Severe ME Research Registry has been created. It gives people with severe and very severe ME from Germany, Austria, & Switzerland the opportunity to participate in research through home visits severe-me-registry.de #SevereME #MEcfs #CFS #PwME #VerySevereME #ChronicFatigueSyndrome
severe-me-registry.de
Severe & Very Severe ME Research Registry
Das Severe and Very Severe ME Research Registry verbindet ME Schwer- und Schwerstbetroffene mit biomedizinischer, häuslicher Forschung.
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Tom Kindlon @tomkindlon.bsky.social · 28/09/2026
“I look fine, but dealing with chronic illness is my full-time job” (Pittsburgh's Public Source) www.publicsource.org/pots-long-co... First person account about coping with chronic illness triggered by COVID infection. #LongCovid #invisibleillness #hiddenillness #chronicillness
publicsource.org
I look fine, but dealing with chronic illness is my full-time job
Jennifer McCalla doesn't look sick, but living with long COVID and POTS is a full-time job. She writes about invisible illness and the fight to be believed.
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Jen the Tired RN @jenthetiredrn.bsky.social · 27/09/2026
A warning for my fellow celiacs:
PRODUCT RECALL
UNDECLARED WHEAT
BROWN SUGAR & POWDERED SUGAR RECALLED DUE TO PRESENCE OF WHEAT
"Certain light brown and powdered sugar products sold under the United, Good & Gather and Crystal Sugar brand names have been recalled due to "Potential Wheat Kernel contamination." Sold in IA, IL, IN, KS, MN, OH PA, TX. See Caption for affected lotsLight Brown Sugar - Packaged in the follow configurations:
1. United, Net Wt. 50 Ibs., (22.68kg). Item Number
810051. Distributed By: United Sugar Producers & Refiners, Minneapolis, MN 55439.
2. Good & Gather (Target), Net Wt 2 lb. (32 oz) 907g Item Number 817773. UPC 0 85239-08454 0. Dist.
By Target Corp.,
Batch numbers -
United Brown Sugar 1. MHD26223, MHD26224, MHD26225, MHD26226, MHD26227, MHD26228, MHD26229, MHD26223, MHD26225, MHD26226, MHD26223, MHD26225, MHD26226.
2. Good & Gather Batch Numbers: MHD26223, MHD26224, MHD26225, MHD26226, MHD26227, MHD26228, MHD26229.Powdered Sugar
1. United 6X, Net Wt. 50 Ibs. ((22.68kg), Item Number 810087. UPC 7 85921-07090 4. Distributed by: United Sugar Producers & Refiners, Minneapolis,
MN 55439.
2. Crystal Sugar, Net Wt. 25 Ibs. (11.3 kg), Item Number 810097. UPC 0 70090-08090 9. Distributed by Crystal Sugars Corporation, Moorhead, MN
3. Good & Gather, Net Wt 2 Ib. (32oz) 907g. Item Number 817774. UPC 0 85239-08455 7. Dist. By Target Corp. Minneapolis, MN 55403.
Batch Numbers
1. United Batch Numbers: MHD26223, MHD26224, MHD26225, MHD26226, MHD26227, MHD26229.
2. Crystal Sugar Batch Numbers: MHD26230
3. Good & Gather Batch Numbers: MHD26223, MHD26224, MHD26225, MHD26226, MHD26227, MHD26228, MHD26229.
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Richelle Sepulveda @richellesepulveda.bsky.social · 27/09/2026
It's really hard to get nutrients and fluids and meds into a cat when you can't grasp his jaw and/or open his mouth. Pretty sure we are going to need a feeding tube, because he just isn't getting enough food and water into him.
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Coyote & Crow Games @coyoteandcrow.bsky.social · 27/09/2026
We've got so many cool ideas for the Between Earth And Sky RPG that we're working on. I think folks who've read the books will be thrilled, and RPG fans will discover some fun concepts and mechanics they haven't seen elsewhere. Plus, look at that cover!
Draft 3d Render of the cover for the Between Earth and Sky roleplaying game.  Art by Raul Cruz.

Monte Cook Shanna Germain Kenna Alexander Rebecca Roanhorse Native Indigenous First Nations RPG TTRPG games gaming tabletop fantasy
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letithappenalreadymama @pnutsmama.bsky.social · 27/09/2026
one of the worst things i realized about higher education is that our population turns over every year/every four years it’s completely new students w zero institutional knowledge and WOW does the school use that to their advantage in these cases
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Ken Burnside @kenburnside.bsky.social · 27/09/2026
It didn't work as a game, because knowing how to do calligraphy is a big ask of people in the 21st Century. I showed this to a colleague who did wargame development for the DoD, and watched his eyes _widen_. He said "Next time you're in DC, bring this, I'm introducing you to someone."
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Ken Burnside @kenburnside.bsky.social · 27/09/2026
As @jfzeigler.bsky.social says, a lot of game and instructional design is "find the simplest model that describes a behavior or set of interactions, and does so robustly." We're great simplifiers. The phase of adding and removing things from games in development is vital.
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Tom Kindlon @tomkindlon.bsky.social · 27/09/2026
From @meresearchuk.bsky.social Exciting research funded by ME Research UK was showcased at the ISLC-PAIS 2026 conference! Discover more about the presentations here: tinyurl.com/246rj47b #mecfs #cfs #pwme #longcovid
RESEARCH UK 
ISLC-PAIS 2026: ME Research UK-funded research highlights 
ME Research UK-funded research presented at ISLC-PAIS 2026 covered topics including: 

Muscle abnormalities 

Gene regulation 
Fat metabolism Cellular waste Q=1, • •• • e _ 

Blood vessel Post Subtle exertional changes in abnormalities malaise brain tissue 
Together, the studies illustrated the range of biological differences being identified in ME/CFS, and in long COVID, while also highlighting important questions for future research. 
INFORM. INFLUENCE. INVEST. 
SCO36942
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Faine Greenwood @faineg.com · 27/09/2026
sorry you had to find out this way
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Faine Greenwood @faineg.com · 26/09/2026
like I suspect many of you on This Website, I think a core reason why I find Eliezer Yudkowsky and his rationalist and effective altruist satellites so intensely annoying is because I had a VERY similar “being a super weird, pretentious, hyper-literate kid” experience - I just, you know, grew up.
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Scott 𐚁 Cataloochee Hogtoe 𐚁 Cave @hellabarnes.bsky.social · 26/09/2026
cf.
femalepope c
Follow My deepest darkest fantasy is that I collapse on the street and I am rushed to the hospital. They perform a bunch of tests and find out I am severely deficient in some kind of vitamin. Then I start taking the vitamin and I become the happiest cleverest person alive because all my problems
were caused by this one deficiency
caracalliope Moreover, everyone gathers around to be tremulously compassionate and discreetly admiring: all this time, you lacked the Vitamin? And
yet you persevered?
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R.S.A. Garcia (BUY THE NIGHTWARD) @rsagarcia.bsky.social · 25/09/2026
I know I haven't updated in a while. There's been a lot going on. - My calcium levels are still worrying. - My eye scans aren't good. - I have to get a CT scan soon. I need help to pay for everything to be done privately. Any amount would be helpful. Thanks. www.gofundme.com/f/help-r-s-a...
gofundme.com
Donate to Help R. S. A. Garcia Pay for Cancer Expenses, organized by Arula Ratnakar
Hi everyone, I'm Rhonda, also known as R. S. A. Garcia, a speculative … Arula Ratnakar needs your support for Help R. S. A. Garcia Pay for Cancer Expenses
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Chuck Tingle @chucktingle.bsky.social · 26/09/2026
what percentage of supposed 'centrist' goofs who long ago accused folks of TROMP DERANGEMENT SYNDROME will ever actually address their own misread? address that actually everyone who said it would be very bad was not 'deranged', but much more in tune than they were. i have yet to see it happen once
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