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Richelle Sepulveda

@richellesepulveda.bsky.social
3.2K followers 1.5K following 3.6K posts

Long Covid, MECFS, ADHD, etc. Patient-led research is my jam. A bit obsessed with GIP.

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Reposted by Richelle Sepulveda
Dr. Johnathan Flowers, Bisexual of the Blade (Alt-text or DIE) @shengokai.blacksky.app · 15m
Help Juno
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Micah @rincewind.run · 5h
“how much shit can you deny yourself? cheese, gender, the fuck’s next?” truly humanity is a rich text
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Prisonculture @prisonculture.bsky.social · 14h
Everything we've been warning about for years re: policing is playing out globally.
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Adam @abrokenbattery.bsky.social · 16h
“You’re fighting the illness, but then you’re fighting every health professional.” Hannah was struggling to digest food and losing weight, but healthcare professionals thought she had an eating disorder. 8 years later, this is still happening to people with severe #MECFS.
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J. Offir, PhD @joffirphd.bsky.social · 07/10/2026
Lol - social psychologists for the win: nothing is immutable, & situational factors matter. (Gift 🎁 link) Excerpts: "Rather than being fixed in the sky at birth, two decades of research suggests personality is far less static than once believed. 'People always retain the... 🧵 wapo.st/4i60RNK
wapo.st
Column | Birth order doesn’t predict your personality. Here’s what does.
New research is challenging assumptions about what determines our personality — and showing that you can change it.
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🌈Dr. Frizzle @swilua.bsky.social · 06/10/2026
In other news, I spent a couple hours learning about the math involved in large language models and I AM SO MAD! IT IS LITERALLY JUST SPICY AUTOFILL IDKY I THOUGHT THE DIP$h!+s IN MY OLD PROGRAMMING CLASSES WOULD BE SMARTER THAN THEY ARE THEY ARE LITERALLY JUST WORSHIPPING A REFLECTION OF HUMANITY
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Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 07/10/2026
A limited number of crab and frog facts advent calendars are now available at SquidFacts.net! These need to be made by hand, so we’ve been phasing them out but I was very lucky to have some help this week making some more in the lead up to December. Get ‘em while they’re here! SquidFacts.net
Two sparkly shiny advent calendars, one with frogs one with crabs
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cursedthing @cursedthing.bsky.social · 06/10/2026
Currently home with Pneumonia after a severe sinus infection. Tested often, wasn't covid/flu for me. But it is THE SUCK. Wear your mask and VOTE EARLY in case you are too sick to vote on Eday!!!
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Claire Willett @clairewillett.bsky.social · 06/10/2026
nothing is more LinkedIn-pilled than assessing the ROI of fun
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Adam @abrokenbattery.bsky.social · 03/10/2026
“ME/CFS patients are deeply inconvenient.” George Monbiot on how people with #MECFS need long term support, but governments and insurers have an incentive to “brush it away” and dismiss patients leaving them “massively mistreated, maligned” and “blamed for their illness”.
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Kim Hu @kim-hu.com · 06/10/2026
dumb things I wish to make for myself
shoddy doodle of a skull with strong arms and legs; text says “this is my gym shirt I am getting strong”
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✊🏼Indigiqueer Hummingbird @riotousmuse.bsky.social · 06/10/2026
Truly.
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Rabbi Danya Ruttenberg @theradr.bsky.social · 06/10/2026
Israeli Finance Minister Bezalel Smotrich, absolute genocidal ghoul, sitting there with a fucking smug smile on his face Please get him, Hague. Every word that comes out of his mouth just adds to his already extensive file. Vile rasha/ evil human being.
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Amanda Finley Digs All the Spooky Things @rubyslippahs.bsky.social · 05/10/2026
A Missouri mom is standing up to data centers -- and they are trying to bury her. Don't let them. Share EVERYWHERE. We don't have deep pockets, but we have social capital. www.gofundme.com/f/support-ka... I'm so sorry, but alt text is not cooperating right now.
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Johnnie Jae @johnniejae.bsky.social · 06/10/2026
Next week is Indigenous Peoples' Day and also my birthday. I have several wishes this year. 1. Federal recognition of Indigenous Peoples' Day. 2. A robot body because mine is not holding up so well these days. 3. To get my ko-fi fully funded cuz see #2. ko-fi.com/johnniejae/g...
ko-fi.com
Support Johnnie Jae ❤️
Indigenous stories, media, and art by Johnnie Jae! Your support helps share Native perspectives with the world and keeps the lights on at home.
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Krista Koeller @kristalerista.bsky.social · 06/10/2026
When I was forced out of my lab, I was able to continue researching because of Morphosource. I would not be a scientist right now if it wasnt for this incredible resource.
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🌈Dr. Frizzle @swilua.bsky.social · 06/10/2026
I very much want to believe this is a magic library full of occult books and they keep misfiring and desperately need an appropriate caretaker to calm them and make the magic accessible for witchcraft again, but the existence of Magic needs to stay secret hence the NDA it’s prob just porn though
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Brendel @brendelbored.bsky.social · 19/06/2026
Getting blocked by the mens wear guy because you keep sending him this picture and asking “thoughts?”
Tidus from Final Fantasy 10
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Jessica Price @delafina777.bsky.social · 05/10/2026
This should be so obvious that it doesn’t need to be said, but given what kind of weekend it’s been on here, apparently it does: If you don’t want old rapists running the world, in office, in the board room, making decisions for all of us get comfortable with “ruining” young rapists’ lives
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Ghostly Bree @mostlybree.kitrocha.com · 05/10/2026
Ok not that much growth we just came up with an idea lol
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Joshua Foust 🪖🎮 @joshuafoust.com · 05/10/2026
In 2010, I sat in on a patrol brief for a BCT in eastern Afghanistan that claimed “pashtunwali revenge” was responsible for why they faced so much violence. When I asked him to remind me why we were in Afghanistan in the first place, the colonel got frustrated and asked me to wait for them outside.
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Amanda Katz @katzish.bsky.social · 05/10/2026
This is absolutely incredible content, like an entire feature film about a giant zucchini competition compressed into two minutes
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Chad Loder @chadloder.dev · 04/10/2026
British banker who exposed Howard Lutnick's ties to Epstein has died, allegedly from suicide.
bbc.com
How US commerce secretary's Epstein links were uncovered by British whistleblower
Simon Andriesz made the discovery about Howard Lutnick in publicly released Epstein files.
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Marisa Kabas @marisakabas.bsky.social · 03/10/2026
this reveals SO MUCH about legacy media
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Shepherd @neolithicsheep.bsky.social · 05/10/2026
You ever have that thing where you're reading a book and you can do the lift for suspension of disbelief for the entire fantastical premise of the thing but then you hit one detail and your brain is like "absolutely not"?
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Michelle Fry @myfry.bsky.social · 02/10/2026
1/ 🧵 Two classic mitochondrial pathways the TCA cycle and OXPHOS are taught as linked but distinct pathways. I’m happy to share our new work out in @cp-cell.bsky.social showing that in Acanthamoeba they're physically linked—with a TCA enzyme incorporated in ATP synthase. www.cell.com/cell/fulltex...
cell.com
Acanthamoeba ATP synthase structure reveals the TCA cycle is tethered to OXPHOS
Acanthamoeba castellanii, a pathogenic amoeba, belongs to an evolutionary branch distinctly removed from humans and fungi. Cryo-EM of the organism’s ATP synthase enzyme using raw mitochondrial lysates...
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Jessica Pishko @jesspish.bsky.social · 05/10/2026
People in jail have the right to vote, but it's rarely accessible. I wrote about how Dallas election officials basically mocked the rights of the legally innocent. boltsmag.org/dallas-count...
boltsmag.org
Dallas County Jail Adds Election Day Polling Place After Pressure from Activists - Bolts
Last summer, Dallas County Sheriff Marian Brown sat inside her car to record a video to post on social media talking about voting inside her jail. Progressive activists had been... Read More
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🎃 Imani Gandy Corn 🎃 @angryblacklady.blacksky.app · 03/10/2026
I bought Dressmaker last night and it's definitely over for all other games. When I learn how to pattern match seams, it's over for you hoes
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Cam Regier @camregier.bsky.social · 05/10/2026
"Mistlberger, a psychology professor at Simon Fraser University, said people may think they want more sun in the evening, but the impact of starting your winter day in the dark is far-reaching."
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Cat Manning @catacalypto.bsky.social · 05/10/2026
this is my favorite genre of social media post and I am soliciting links or screenshots to your favorites
Jesse Raub @jesseraub.online
King Darius looking down at Daniel in the pit:
Norm Charlatan @normcharlatan....
Man, what are the Lions doing?
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Dr. Mike Sellraiser III: Sell on Earth @profmikesell.bsky.social · 14/09/2026
I have an unusual opportunity: I've been offered the opportunity to display the visual art of a tabletop roleplaying game in one of our campus galleries for 6 months. What game and artists (including layout designers) would you recommend? We'd need to be able to set this up quickly!
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Kelly @broadwaybabyto.bsky.social · 05/10/2026
If you’re still wearing a mask, thank you. Please know you’re not alone. Many of us still mask, test and isolate when sick. Being the lone masker can be difficult, but your long term health is worth it. As a high risk, immunocompromised person… I see and appreciate you.
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Gail Simone @gailsimone.bsky.social · 04/10/2026
You guys want to hear a short but adorable story that happened right in front of me at the baggage claim in NYC yesterday? I wasn't part of it and there are bits I didn't catch but holy crap, I can't stop thinking about it.
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Patient-Led Research Collaborative @patientled.bsky.social · 01/10/2026
A new publication is out from PLRC member Dr. Alison Cohen of UCSF! "We encourage state legislatures to pass legislation that requires all schools to make changes to their infrastructure to support cleaner air to protect students & teachers." #LongCovid
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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Prisonculture @prisonculture.bsky.social · 04/10/2026
time.com/article/2026...
time.com
Revisiting Childhood Hobbies Is a Way to Learn Who You Are as an Adult
Returning to a childhood hobby can engage the past as we remember it, the present, and the future we imagine, writes Rainesford Stauffer.
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Prisonculture @prisonculture.bsky.social · 04/10/2026
The reality in this country is that the VAST majority of people who experience sexual violence will never tell the cops. Ever. This born out by all statistics but if you've survived sexual violence you also know this from your personal experience. There are many reasons for this. But again...
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Amyville Hoyrror @amyhoy.bsky.social · 04/10/2026
famously people cannot draw an accurate bicycle so clearly nobody knows how bicycles work despite the fact that they’re a wholly human-made object and produced by several companies and all, when it comes down to it, basically interchangeable in form and function IT’S a MYSTERY
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Some Random Susan @anysusan.bsky.social · 04/10/2026
Aw, so pure and lovely
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Tom Cox @dj-acid-reflux.bsky.social · 04/10/2026
A thread about a great cat, and the post-retirement creative evolution of a great artist, in 20 images...
My late cat The Bear in a box marked Hotel California, realising he can check out but he can never leave.
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It's ME(Jaime) @exceedhergrasp1.bsky.social · 04/10/2026
Continuing at the top of Background, Section 2.
    Background
    2  A brief introduction to research design

2  A brief introduction to research design

To consult the statistician after an experiment is finished is often merely to ask him to conduct a post mortem examination. He can perhaps say what the experiment died of.

— Sir Ronald Fisher

Presidential Address to the First Indian Statistical Congress, 1938. Source: http://en.wikiquote.org/wiki/Ronald_Fisher
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Dr Sam Hirst @romgothsam.bsky.social · 04/10/2026
Acknowledge that people are interested not in reading the same thing over and over again, but in exploring one thing from an almost infinity of approaches an angles. Of exploring different facets of the thing itself. Of making a familiar thing new, of using to explore different ideas or realities.
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Nanoraptor @nanoraptor.danamania.com · 04/10/2026
Apropos of weirdos(derogatory) being weirdos again.
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Victoria Redfern @victoriaredfern.bsky.social · 04/10/2026
Kemi Badenoch saying people earning a million pounds a year shouldn't be punished for working hard, and in all my years on this earth I don't think I've ever been so naïve as to think people getting that much money are working hard.
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Richelle Sepulveda @richellesepulveda.bsky.social · 04/10/2026
Some days I start writing a post and then realize I don't have the energy to deal with replies, either positive or negative. Being perceived often carries the obligation to demonstrate you perceive your perceiver.
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Third Crow @thirdcrow.bsky.social · 04/10/2026
Some days I think, “why don’t lots of people read and like what I post”. Other days I’m more, “ah! The joy of not being perceived”. It’s the odd smushing together of wanting to share thoughts but not wanting to be visible. 🤷🏻‍♂️ Which, I guess, also explains why I am the sporadicest of posters…
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Tom Cox @dj-acid-reflux.bsky.social · 04/10/2026
Forgive me for feeling emotional seeing stuff like this. As soon as I'd finished this book my ex-publisher collapsed, took my earnings and I had no idea whether it would even come out. I got the impression everyone who read it before it was published hated it. All I knew was I felt it was my best...
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Dr Zara Bain @zaranosaur.bsky.social · 04/10/2026
Two things 1/ it’s been a rough year for all businesses and my social enterprise is no different If you have transcription needs or leads on people who do, please do get in touch for a quote 2/ guess what guess what I’ve got a surprise new epistemic injustice offer (or three?!) coming soooooon
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ceej @ceej.online · 04/10/2026
“how do we win back trump voters in 2026” we don’t. we create an environment where admitting to voting for trump is so socially embarrassing as to render them completely inert. you don’t “win back” trump voters. you demoralize them into staying home. you make it a dunce cap
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Olivia Just Wants Tech To Be Fun Again @kingdomfantasy6.bsky.social · 04/10/2026
This is what I'm talking about when I bring up that genAI bots are making it impossible for an open web to actually exist. It becomes expensive, a pain, and domain providers like cloudflare are profiting off both the people making bots and the people who don't have the tech skills to fight them off
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Pookleblinky @pookleblinky.bsky.social · 30/09/2026
And we already know from Anthropic's own code release that they do absolutely *wildly* inefficient stupid shit like "download the entire database each time you need to do a search operation, in a dozen different places"
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