Neuropsychopharmacology - Genetic pleiotropy differentially linking brain variation to cannabis use and cannabis use disorder

Background: The biological mechanisms linking generalized anxiety disorder (GAD) and COVID-19 remain poorly understood, despite substantial evidence of their comorbidity. To address this gap, we exami...

Postdoc and postgrad positions open in Dr. Renato Polimanti’s group at the Yale University School of Medicine.

Multi-ancestry genome-wide association analyses coupled with multi-omics integration identify new risk loci for endometriosis and adenomyosis, shed light on underlying molecular mechanisms and suggest...

Postdoc and postgrad positions open in Dr. Renato Polimanti’s group at the Yale University School of Medicine.

Endometriosis, a chronic inflammatory disease that affects approximately one in ten women of reproductive age—around 190 million worldwide—remains poorly understood from a biological perspective, which has historically hindered both its accurate diagnosis and the development of effective treatments.

Nature Genetics - Multi-ancestry genome-wide association analyses coupled with multi-omics integration identify new risk loci for endometriosis and adenomyosis, shed light on underlying molecular...

Suicide is a leading cause of death globally, with disproportionately rising rates in Latin America. Despite increasing global interest in the biology of suicidal behavior, Latin American and…

Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.

WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits - Volume 55

INTRODUCTION Limited information is available regarding sex differences in the relationship of socioeconomic status and cognitive performance with Alzheimer's disease and related dementias (ADRD) fa...

Endometriosis. Experiencias traumáticas. Genética. Enfermedad inflamatoria crónica. Enfermedad sistémica.

This seminar by Renato Polimanti provides a comprehensive theoretical background regarding the integration of causal inference and human genetics.

This case-control study analyzes genotypic and phenotypic information from individual-level UK Biobank data, along with genome-wide information from a large meta-analysis and the FinnGen cohort, to determine the relationship between traumatic experiences and endometriosis.

This case-control study analyzes genotypic and phenotypic information from individual-level UK Biobank data, along with genome-wide information from a large meta-analysis and the FinnGen cohort, to de...

The University of Barcelona has participated in an international study that has found new evidence linking traumatic experiences and stressful events with endometriosis, a chronic systemic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus.