C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.

Postacute sequelae of COVID-19 or “PASC” is a common but heterogeneous condition associated with significant morbidity. Although its pathogenesis remains poorly understood, proposed underlying mechan...

npj Vaccines - Maternal vaccination against COVID-19, influenza, pertussis, and respiratory syncytial virus: a scoping review

npj Primary Care Respiratory Medicine - Risk factors of post-COVID-19 symptoms, a cross-sectional study in patients with asthma and chronic obstructive lung disease

Introduction Although the COVID pandemic has gradually subsided, many patients have experienced complicated long-term symptoms, collectively known as “long-COVID”, which is commonly associated with pe...

Background Long COVID is a persistent contributor to population morbidity, and people with disabilities experience substantial and often avoidable health disadvantage worldwide. Whether long COVID is ...

A TOTAL of 333 people have been treated at the HSE's Long Covid clinic in Limerick since it opened in 2022.

Persistent symptoms can harm the lungs and other organs, including the brain.

Immune-based therapies have transformed the treatment of cancer and inflammatory and autoimmune diseases, but treatment is often suboptimal and the ability to predictably harness the immune system for...

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A review highlights how in vitro joint models adapted from arthritis research can be leveraged to study chikungunya virus–driven joint inflammation, immune–stromal interactions, and matrix degradation...

Emmerson et al. demonstrate that the CXCR3-CXCL10 chemokine signaling pathway is important for brain-infiltrating T cells in tau-mediated neurodegeneration. Blocking CXCR3 reduces T cell entry and pro...

Nucleoside analogs show protective and therapeutic effects in a mouse model of multiple sclerosis (MS) and association with reduced MS risk in humans.

This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. W...

Two that are promising, and one that is difficult to talk about

Complex chronic conditions represent a growing health burden that is poorly understood and inadequately managed within current health systems. This review focuses on the potential of epigenetic DNA me...

McColl et al. demonstrate that SARS-CoV-2 impairs placental iron efflux, leading to persistent iron accumulation and impaired maternal-fetal iron transfer, and activates ferroptosis signaling, which m...

The gut and lung, though anatomically distinct, are connected through a dynamic, bidirectional communication network known as the gut-lung axis, whereby intestinal microbiota, immune cells, and microb...

Estudios originales - Publicado el 23 de septiembre de 2026 | http://doi.org/10.5867/medwave.2026.08.3234

Filip et al. describe long COVID as a complex entity involving cognitive impairment linked with altered cerebral microstructure. The prominence of neuroinf

Scientific Reports - Visual functions and neuroretinal status in relation to cognitive functions and fatigue in post-COVID-19: an exploratory study

SARS-CoV-2 coronavirus infections are associated with long term vascular dysfunction, yet the drivers remain unclear. We hypothesized that remnant Betacoronavirus antigens remain in circulation and or...

Abstract. Introduction: This report presents an unusual case of sequential, pharmacologically confirmed iatrogenic bilateral Horner syndrome followed by bilateral Adie’s tonic pupil, highlighting the ...

Immunoglobulin (Ig) replacement therapy is a current treatment for patients with certain immune deficiencies. Multiple pathophysiologic mechanisms have indicated the potential benefit of Ig replacemen...

Receiving a fourth dose of COVID-19 vaccine was associated with a lower risk of being diagnosed with post COVID-19 condition compared with three doses, although the absolute risk reduction was small. ...

Long COVID, characterized by the persistence of symptoms beyond the acute phase of SARS-CoV-2 infection, affects an estimated 10-30% of individuals with COVID-19, representing around 400 million peopl...

BackgroundNeutrophil extracellular trap (NET) formation (NETosis) has been proposed as a contributor to the pathophysiology of Long COVID (LC). However, it r...

Autonomic nervous system (ANS) dysfunction is a central feature of long coronavirus disease syndrome, yet little is known about how it develops during and after severe acute respiratory syndrome coron...

Long COVID, including the difficulty in defining it and caring for patients experiencing it, is discussed by JAMA Senior Editor Derek C. Angus, MD, MPH, and E. Wesley Ely, MD, MPH, professor of medici...

Modified HIV drug reverses vision loss and paralysis in multiple sclerosis model.