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Gabriel R. Fries, Ph.D.

@friesgabriel.bsky.social
223 followers 288 following 47 posts

Assistant Professor of Psychiatry at the University of Texas Health Science Center at Houston. Biological basis of bipolar disorders and suicide. #epigenetics #aging #bipolardisorder #suicide #metabolicpsychiatry

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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 29/09/2026
We invite you to join us for the 2026 UTHealth Houston Mood Disorders Conference: The Many Faces of Bipolar Disorder, Oct. 16–17. Join us and register today: go.uth.edu/Mood2026
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Reposted by Gabriel R. Fries, Ph.D.
ACNP @acnporg.bsky.social · 06/08/2026
Please join us in Congratulating the 2026 ACNP Travel Award Class! 👏🤩 Click Here ➡️ tinyurl.com/5bzaz8va for more information on Travel Awards. 📝
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Reposted by Gabriel R. Fries, Ph.D.
Biological Psychiatry @biologicalpsych.bsky.social · 29/07/2026
Individuals with schizophrenia, bipolar disorder, and depression are more likely to lose focus during listening but do so in unique ways: those with schizophrenia zone out, those with depression experience a distracted state with split attention, and each is linked to a unique brain signature.
biologicalpsychiatrycnni.org
Distinct Attentional Control Profiles during Language Comprehension in Major Mental Health Disorders
The current study combined behavioral and EEG measures to investigate variations in attentional state during comprehension of spoken stories in a clinical sample that included participants with…
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Reposted by Gabriel R. Fries, Ph.D.
Erik Reinbergs @ereinbergs.bsky.social · 15/04/2026
Happy first day of #SRS26! www.suicideresearchsymposium.com #suicideprevention
suicideresearchsymposium.com
SRS 2026
We are delighted to announce that the fifth annual Suicide Research Symposium will be taking place April 15-17, 2026. Like previous years, this Symposium will be free and take place virtually. This will be a place where you have the opportunity to: Present recent research findings Stay informed
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Reposted by Gabriel R. Fries, Ph.D.
Biological Psychiatry @biologicalpsych.bsky.social · 14/04/2026
There is encouraging but heterogeneous evidence linking epigenetic age acceleration to worse cognitive performance. More research is needed to establish epigenetic aging tools as premature cognitive aging biomarkers.
bpsgos.org
Epigenetic aging and cognitive performance in general and psychiatric populations: a systematic review and narrative synthesis
Epigenetic aging and age-related cognitive decline both show substantial variability across individuals. While a potential link between the two is increasingly studied in both general and psychiatric…
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 13/04/2026
Attending the 5th Annual Suicide Research Symposium this week (lnkd.in/gpRjbxDw)? Don't miss the presentation by our brilliant PhD student Valeria Arredondo on Wed, April 15th, on the methylomics/transcriptomics of suicide/bipolar disorder (teaser: long non-coding RNAs!!). #suicide #bipolardisorder
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Reposted by Gabriel R. Fries, Ph.D.
Erik Reinbergs @ereinbergs.bsky.social · 10/04/2026
Still time to register for the Suicide Research Symposium next week! It's such a good conference and it's free so check it out! Yours truly will be moderating the session on DBT and the session on youth and young adult risk screening! www.suicideresearchsymposium.com #suicideprevention #DBT
suicideresearchsymposium.com
SRS 2026
We are delighted to announce that the fifth annual Suicide Research Symposium will be taking place April 15-17, 2026. Like previous years, this Symposium will be free and take place virtually. This will be a place where you have the opportunity to: Present recent research findings Stay informed
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 07/04/2026
New publication alert! 🚨 We analyzed the shared genetic architecture of suicide attempt (SA) and ideation (SI) across 13 traits using large-scale GWAS. We found shared loci implicating neurodevelopmental, immune, and metabolic pathways, with distinct signatures for SA vs SI. doi.org/10.1016/j.eu...
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Reposted by Gabriel R. Fries, Ph.D.
Rethink Mental Illness @rethinkcharity.bsky.social · 30/03/2026
Bipolar is one of the most common mental health diagnoses but still remains hugely misunderstood. For #WorldBipolarDay, we want that to change.
This illustration is titled "This World Bipolar Day, we're thinking of anyone who..." and shows a person in the center with various challenges depicted around: problems with sleep, no energy to face the day, side effects from medication, stigma at work, struggling to find words, and difficulty concentrating.
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 27/03/2026
Interesting results with careful assessment of genetic influence and multiple confounding variables on DNA methylation in a clinical trial for psychotherapy. Wonderful work, @kirahoeffler.bsky.social and colleagues!
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Reposted by Gabriel R. Fries, Ph.D.
Marija Kundakovic @kundakoviclab.bsky.social · 15/03/2026
Extremely excited to give a #TEDx talk on perimenopause & mental health at #TEDxFordhamUniversity on March 26! now.fordham.edu/university-n... If you're interested in attending in person, here's the link to register: fordham.edu/tedx/ Can't wait! 😎 ❤️‍🔥 #WomensHealth @fordham.edu
now.fordham.edu
TEDxFordham University Returns to Illuminate the Ideas Shaping Our Shared Future
Making an impact on the world starts with bold ideas, and at Fordham, those ideas come from a diverse mix of voices, from a reality television star to a philosophy
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 16/02/2026
Excited and honored to share that I’ve received the 2026 Gerald L. Klerman Young Investigator Award from DBSA! This recognition means a great deal and reflects the incredible mentors, collaborators, trainees, and research participants who make our work possible. www.dbsalliance.org/about/gerald...
dbsalliance.org
2026 Klerman Award Winners - Depression and Bipolar Support Alliance
Gabriel R. Fries, PhD | 2026 Young Investigator Award Gabriel R. Fries, PhD, is an Assistant Professor in the Faillace Department of Psychiatry and Behavioral Sciences at McGovern Medical School … Con...
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Reposted by Gabriel R. Fries, Ph.D.
Society for Neuroscience @sfn.org · 13/02/2026
Looking for advice on navigating these unprecedented, challenging times in neuroscience research? Attend this Meet-the-Expert webinar to learn how to seek funding, maintain a work-life balance, and more. Register now🔗: vist.ly/4rg6g #neurosky #neuroskyence #academicchatter
SfN Neuronline logo. Webinar series: Meet-the-Expert. No Pain, No Gain: Advice for Turbulent Times in Neuroscience Research. Wednesday, February 25, 1–2 p.m. EST. Cheryl L. Stucky, PhD.
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 11/02/2026
Nice to see a secondary analysis of our hippocampal DNAm data (GEO: GSE129428). Ohi et al. show that 🧠 hippocampus-derived methylation risk scores are significantly associated with #bipolardisorder in 🩸 blood, pointing to cross-tissue epigenetic signatures: onlinelibrary.wiley.com/doi/10.1111/...
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Reposted by Gabriel R. Fries, Ph.D.
Biological Psychiatry @biologicalpsych.bsky.social · 03/02/2026
"Genomic research on suicidality in Latin America is growing but remains fragmented and underpowered. Increasing representative sampling, implementing ancestry-aware methods, and fostering collaborations are essential to advance research and inform prevention strategies in these populations."
biologicalpsychiatryjournal.com
Genomic Studies of Suicidal Thoughts and Behaviors in Latin American Populations: A Systematic Review
Suicide is a leading cause of death globally, with disproportionately rising rates in Latin America. Despite increasing global interest in the biology of suicidal behavior, Latin American and…
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 30/01/2026
Why do some individuals with serious mental illness experience earlier age-related decline? 🧬 Our new paper in @npp-journal.bsky.social investigates the role of premature biological aging ⌛ in SMI and what it means for future treatments. Check it out here: www.nature.com/articles/s41...
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 19/01/2026
Very excited to share our latest 📖 publication from the Latin American Genomics Consortium Suicide Working Group, now in press in @biologicalpsych.bsky.social, where we systematically review genomic 🧬 studies of suicidality in Latin American populations: linkinghub.elsevier.com/retrieve/pii...
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 15/01/2026
Congrats to all new #ACNP Associate Members, and special shoutout to my friend/Science hero @drsarahsperry.bsky.social 🥳🥳
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 04/12/2025
Grades are posted, and our Neurobiology and Neuroanatomy course is officially done for the semester!!! 🥳 🧠 @uthealthhouston.bsky.social
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 11/11/2025
Honored to have been part of the 2025 International Summit on Suicide Research in beautiful Boston. #suicide #epigenetics #art
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Dr Georgina Hosang @drhosang.bsky.social · 10/11/2025
📢 calling colleagues to participate or help with recruitment for study on #depression experienced by #neurodivergent young people Specifically: 👩‍👧‍👦Parents/carers 💼Mental health professionals See poster @ehayashibara.bsky.social @qmul-wiph.bsky.social @qmulpsychiatry.bsky.social
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 07/11/2025
🚨New publication alert! We tested the use of blood bulk or L1CAM (of putative 🧠 origin) extracellular vesicles (EVs) to identify #miRNA signatures in #bipolardisorder. Lots of lessons learned and key insights into the use of EVs for biomarker discovery: www.tandfonline.com/doi/full/10....
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Guillaume Bourque @guilbourque.bsky.social · 09/10/2025
🚨 New paper alert on telomeres! 🚨 Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 09/09/2025
Good news deserves to be celebrated! 🥳 Happy to share that our lab was recently awarded 1) a Pilot grant from @mcgovernpeds.bsky.social and 2) a CaDRE award from UTHealth Psychiatry to develop novel in vitro neuronal models to investigate mechanisms linked to suicide and bipolar disorder 🧠🔬
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 14/08/2025
Updated lab photo from our Department’s Annual Behavioral Health Research Day @uthealthhouston.bsky.social
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Neuropsychopharmacology @npp-journal.bsky.social · 24/07/2025
Are you an international (outside the US) scientist looking to attend the annual @acnporg.bsky.social meeting in January?🌎 Then see below for an opportunity to join us for #ACNP2026 in the Bahamas 😎🏖️👇
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 17/06/2025
Latin America has experienced an increase in suicide rate, contrasting with a global decline. We review possible reasons for this here: www.sciencedirect.com/science/arti... Led by Dr. Brenda Cabrera-Mendoza and @renatopolimanti.bsky.social, 1st publication from the LAGC Suicide Working Group.
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 13/06/2025
Could premature aging help explain the variability in Alzheimer's risk in bipolar disorder (BD)? Excited to share our latest findings on the link between epigenetic aging and amyloid biomarkers in BD, now published in the American J of Geriatric Psychiatry: www.ajgponline.org/article/S106...
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Maya Schumer! @mayaschumer.bsky.social · 26/05/2025
I recently—for the first time—spoke openly & honestly about my 11+year journey w/ #BipolarDisorder +chronic su!cidality on my friend @UmaRChatterjee podcast @AChatWithUma. Grateful to Uma for creating the opportunity for me to speak truth to stigma. Check out Part 1! (part 2 coming this week!)
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Jamie Hanson @jamielarsh.bsky.social · 23/05/2025
Biological age prediction in schizophrenia using brain MRI, gut microbiome and blood data www.sciencedirect.com/science/arti...
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 12/05/2025
I had a very nice conversation last week with João Freitas on the topic of Epigenetics, Psychiatry, and the Future of Mental Health. 🧠🧪 Check out my interview 🎙️ on the Mind Body Science Podcast here: YouTube: www.youtube.com/watch?v=ubIc... Spotify: open.spotify.com/episode/54HO...
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 08/05/2025
Time to say goodbye to one of my first mentees, Rohit Jha, who is brilliantly graduating from Rice University this week. Rohit led many of our studies with a lot of creativity and enthusiasm, and I'm very grateful for what he has done for our lab over the last 3+ years. We will miss you, Rohit! 👨‍🎓
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 28/04/2025
Final leg of the 🇨🇦 tour was in Hamilton: a visit and talk at the beautiful McMaster University and St. Joseph's (plus seeing really good friends!). So excited to learn of the work they have been doing.
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 27/04/2025
Loved learning more about the awesome work @robynmcquaid.bsky.social and Ayeila Daneshmend are doing on the #epigenetics of #suicide #SOBP2025
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 26/04/2025
SOBP just reminded me of the amazing work being done by Dr. Patricia Silveira's lab at McGill University!
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 25/04/2025
The first day of the annual meeting of the Society of Biological Psychiatry was a success (and a lot of fun)!
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 23/04/2025
Exciting day 2 of the 🇨🇦 tour: Metabolic Psychiatry in Severe Mental Illness Meeting at the beautiful Hart House, UofT @uoft.bsky.social
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 23/04/2025
Day 1 of the 🇨🇦 tour: productive visit and talk @camhnews.bsky.social Loved visiting the UoT campus, as well. Thank you, Dr. Erica Vieira, for hosting me!
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 10/04/2025
🚨 New preprint from our lab explores a potential biological mechanism underlying the heterogeneity in Alzheimer's disease 🧠 risk among individuals with bipolar disorder. Check it out here: www.medrxiv.org/content/10.1... #bipolardisorder #Alzheimers #aging #amyloid #epigenetics
medrxiv.org
Association between epigenetic aging acceleration and amyloid biomarkers in bipolar disorder
Objectives Bipolar disorder (BD) has been associated with an elevated risk of Alzheimer’s Disease (AD). We assessed AD biomarkers in BD and tested whether epigenetic aging (EA) acceleration is a poten...
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Reposted by Gabriel R. Fries, Ph.D.
ACNP @acnporg.bsky.social · 31/03/2025
ACNP Travel Award Applications open TODAY for the ACNP 64th Annual Meeting: January 12-15, 2026, Nassau, Bahamas. Deadline to Submit is May 8, 2025, at 5:00 pm Central. acnp.org/annual-meet... #ACNP2026 #travelawards
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Reposted by Gabriel R. Fries, Ph.D.
Jamie Hanson @jamielarsh.bsky.social · 25/03/2025
A cross-generational methylomic signature of infant maltreatment in newborn rhesus macaques www.sciencedirect.com/science/arti...
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Reposted by Gabriel R. Fries, Ph.D.
Marija Kundakovic @kundakoviclab.bsky.social · 11/03/2025
My lab is hiring 2 postdocs on an NIH-funded grant characterizing molecular & cellular changes in the human brain across menopausal transition. Other neuroepigenomics projects are also available. We plan to hire a wet lab scientist and a bioinformatician. Please RT! kundakoviclab.com More info 👇
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International Society for Bipolar Disorders @isbd4.bsky.social · 10/03/2025
Join our Early & Mid-Career Committee as they launch its Community of Practice on Tuesday, March 25th. This online event is for early & mid-career people working in the field of #bipolardisorder. Don't miss your chance to connect with others in the field! Register here: forms.gle/cobckZRdVK14...
forms.gle
ISBD Early Mid-Career Community of Practice Event Registration
Please complete the fields below to register for the ISBD Community of Practice Virtual Launch Event on March 25th, 2025. Please note, space for each event is limited and will be allocated on a first...
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 28/02/2025
🚨The @isbd4.bsky.social EMCC will host an online event to launch its 'Community of Practice' on Tuesday, March 25th, 2025. The event is free and open to all, but we require those who will attend to complete a registration form by Thursday, March 20th at 5:00PM EDT: docs.google.com/forms/d/e/1F...
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Reposted by Gabriel R. Fries, Ph.D.
Andrew McIntosh @mcintosh2001.bsky.social · 24/02/2025
Many thanks to all of the collaborators and funders (esp @wellcometrust.bsky.social & @ukri.org) who made this DNA methylome-wide study of antidepressant exposure possible www.nature.com/articles/s41...
nature.com
Insights from a methylome-wide association study of antidepressant exposure - Nature Communications
The mechanism of currently prescribed antidepressants is incompletely understood. Here, the study identifies associations between antidepressant use and DNA methylation, highlighting shared signals ac...
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Jordan Smoller @jorsmo.bsky.social · 10/02/2025
Lithium wins for treatment of bipolar depression Real-world effectiveness of pharmacological maintenance treatment of bipolar depression: a within-subject analysis in a Swedish nationwide cohort - The Lancet Psychiatry www.thelancet.com/journals/lan...
thelancet.com
Real-world effectiveness of pharmacological maintenance treatment of bipolar depression: a within-subject analysis in a Swedish nationwide cohort
Since medications are typically started when depressive symptoms re-emerge, all treatments might appear less effective than they actually are when the reference is non-use of medication. Lithium was t...
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Dr. Sarah Sperry @drsarahsperry.bsky.social · 07/01/2025
So proud of @julialsmith.bsky.social!!! Her first, first-author pub is now online!!! 🎉🥳 A quick 🧵: intensity/frequency of cannabis use and levels of alcohol and substance use impairment prospectively predicted higher SI in bipolar disorder
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Rodrigo Duarte, PhD @3rduarte.bsky.social · 13/12/2024
Ei! Você é pesquisador(a) brasileiro(a) e quer fazer doutorado ou pós-doc em um país de língua inglesa, mas não sabe por onde começar? Me manda uma mensagem! Talvez eu possa te ajudar. 😊
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Gabriel R. Fries, Ph.D. @friesgabriel.bsky.social · 18/12/2024
Farewell lunch to celebrate the months we had Iago Santos with our lab @uthealthhouston.bsky.social. With funding from @agenciafapesp.bsky.social, Iago (originally from Diego Rovaris' lab at USP) quickly became an expert in epigenetic analyses and a true asset to our lab. We'll miss you in Houston 🤠
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