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Matt Pratt

@mattrpratt.bsky.social
272 followers 392 following 27 posts

Professor of Chemistry at University of Southern California; www.theprattlab.com; glycoscience, protein aggregation, neurodegeneration

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Reposted by Matt Pratt
Kimberly Beatty @beattylab.bsky.social · 28/09/2026
Please share: OHSU is hiring an Assistant Prof. in the Dept. of Chemical Physiology & Biochemistry. We are looking for a chemical biologist who will apply novel chemical tools in physiological systems. Apply online: www.ohsu.edu/human-resour... (Job # 2026-41667).
ohsu.edu
OHSU Faculty, Physician and Academic Jobs in Oregon
Find higher education faculty, physician and research jobs and build your academic health career at OHSU in Portland, Oregon.
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Senator Patty Murray @murray.senate.gov · 21/09/2026
Breast cancer patients shouldn’t be denied hope of a new lifesaving treatment because Russ Vought thinks women’s health research is woke. I will fight this plan tooth and nail.
nytimes.com
White House Moves to Take Control of N.I.H. Grants
Federal officials are drafting an executive order that would place grants under review by an outside panel, the latest effort to redirect billions of dollars in research spending.
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Maja Köhn @mkoehn.bsky.social · 09/09/2026
From detection of new PTMs (Chu Wang), diverse approaches to target protein aggregation (Mi Hee Lim) to new photocage designs (Peter Kele) and target ID of new electrophiles (Yimon Aye): #EMBOChemBio offers to learn from different areas and amazing methods to inspire own research! #ChemBio #ChemSky
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Allison Gill @muellershewrote.com · 11/09/2026
Okay everyone. Here’s the YouTube interview with @jimmykimmel.com and @jamestalarico.bsky.social You know what to do. Watch it. Share it. Donate. Bury them. youtu.be/WLDE9LrGpNk?...
youtu.be
Jimmy Kimmel’s Interview with James Talarico That the FCC Doesn’t Want You To See
YouTube video by Jimmy Kimmel Live
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Jeremy Baskin @jeremybaskin.bsky.social · 04/09/2026
Come be my colleague! Cornell Chemistry & Chemical Biology is hiring TWO tenure-track faculty: assistant professor in chemical biology and open rank in quantum materials. Applications due Oct 15 — academicjobsonline.org/ajo/jobs/32602 #chemjobs
academicjobsonline.org
Cornell University, Chemistry and Chemical Biology
Job #AJO32602, WDR-00061091 Assistant Professor/Open Rank Professor - Chemistry and Chemical Biology, Cornell University (Ithaca, NY), Chemistry and Chemical Biology, Cornell University, Ithaca, New Y...
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Matt Pratt @mattrpratt.bsky.social · 04/09/2026
@tommorelloofficial.bsky.social We are celebrating your former band mate and Nobel winner Carolyn Bertozzi’s 60th birthday in October. Over 300 people will be in attendance at Stanford. I am a former student of her’s, and a happy birthday message from you would be amazing to include.
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Samuel A. Myers' lab @samyers-lab.bsky.social · 01/09/2026
OGT complexes....
static.klipy.com
Homer Simpson Drools with Anticipation
ALT: Homer Simpson Drools with Anticipation
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Jenna Norton @jenna-m-norton.bsky.social · 26/08/2026
Russell Vought’s OMB is inexplicably removing comments on the federal financial assistance proposed rule that mention how NIH research saved the life of Vought’s own daughter. Impeachvought.com
impeachvought.com
Impeach Vought
We are current and former federal workers from across the government. We have witnessed first-hand the harm Russell Vought has inflicted on American communities. We are urging Congress to act now to p...
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 30/07/2026
“If the government hadn’t funded research into desert lizard venom, we wouldn’t know about semaglutide…If research scientists hadn’t studied how bees optimize nectar foraging within a colony, we wouldn’t have the algorithm that assigns internet traffic” www.publicnotice.co/p/michael-kr...
publicnotice.co
The new "science golden age" looks suspiciously like a grift
Trump wants to run scientific research like his family business.
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 24/07/2026
@dereklowe.bsky.social on point with no sugar coating 👏 👏 👏 www.science.org/content/blog...
science.org
The Assault On Science Funding Continues
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Matt Pratt @mattrpratt.bsky.social · 14/06/2026
Climate change acutely focused on the exterior of my plane this morning @ 172F.
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 31/05/2026
Excellent, concise summary of the threats of recent OMB proposal and suggested action items. DEADLINE TO SUBMIT PUBLIC COMMENTS IS JULY 13, 2026 AT 11:59 PM EASTERN TIME elizabethginexi.substack.com/p/what-we-ne...
elizabethginexi.substack.com
What We Need to do NEXT: OMB’s Proposed Federal Financial Assistance Rule (OMB-2026-0034)
What OMB’s Proposed Federal Financial Assistance Rule Means in Practice
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GlycoNet @glyconet.bsky.social · 31/03/2026
Congratulations to GlycoNet Investigator Dr. Matthew Macauley on receiving the Horace S. Isbell Award, recognizing his contributions to carbohydrate (sugar) research. Read more: canadianglycomics.ca/glyconet-inves… #Glycotime #Glycoscience
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Luke Lavis @rhodamine110.bsky.social · 24/03/2026
The best two years you can spend before graduate school! Get the hands of a 4th-year grad student contributing to Open Science: bit.ly/47mU5xx Or join an interdisciplinary AI/biology team (don't worry, the AI still needs you to do the actual experiments): bit.ly/4taqzni Both at Janelia!
bit.ly
Research Technician - Tool Translation Team
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Summary: We are seeking a chemist to join the Tool Translation Team, "...
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Keri Backus @keribackus.bsky.social · 06/02/2026
Excited to share our new paper and lipid- and protein-directed photocatalytic labeling method (POCA) just out in @natchembio.nature.com. tinyurl.com/2kcxuvvv. Big congrats to first author Andrew Becker and the whole team for launching our lab into the wild world of singlet oxygen interactomics.
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Noam Ross @noamross.net · 02/02/2026
NSF GRFP applicants (and mentors): Was your application Returned Without Review and deemed ineligible despite fitting in the allowed topics? 1) Write NSF 2) Write your Congressperson 3) CC us at grfp@grant-witness.us so we can compile + follow up Details and template at grant-witness.us/grfp-letter
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Balyn Zaro @balynzaro.bsky.social · 06/01/2026
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines. www.biorxiv.org/content/10.6...
biorxiv.org
Ninhydrin as a covalent warhead for chemical proteomic-enabled discovery and selective engagement of reactive arginines
Covalent molecules have emerged as next-generation therapeutics and as powerful tools for perturbing fundamental biological processes. Chemical proteomic methods to screen for reactive proteinaceous a...
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Dmitry Eremin @dmeremin.bsky.social · 27/09/2025
🚨 3 weeks to go! 🚨 Join us for the 2nd LA Mass Spec Day 🧪✨ 📅 Oct 17, 10am–5pm 📍 UCLA South Bay Campus Plenary talks • Contributed talks • Posters • Networking 👉 Register: lnkd.in/gFdW9rfG 👉 Abstracts: lnkd.in/gb-Qq7d5
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Matt Pratt @mattrpratt.bsky.social · 08/09/2025
media.tenor.com
a cartoon robot is drinking from a bottle with a brown label
ALT: a cartoon robot is drinking from a bottle with a brown label
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Scripps Research @scripps.edu · 13/08/2025
Congrats to Benjamin Cravatt on receiving the 2025 Tetrahedron Prize for Creativity in Bioorganic & Medicinal Chemistry from @elsevierconnect.bsky.social, honoring his pioneering activity-based protein profiling (ABPP) to study and target disease-relevant proteins.
magazine.scripps.edu
Benjamin Cravatt awarded Tetrahedron Prize for Creativity - Scripps Research Magazine
Benjamin Cravatt, the Norton B. Gilula Chair in Biology and Chemistry at Scripps Research, will receive the 2025 Tetrahedron Prize for Creativity in Bioorganic and Medicinal Chemistry. Established in ...
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Fleur Ferguson @fleurmferguson.bsky.social · 11/08/2025
Excited to share our latest work developing molecular glue degraders of ZBTB11, now out in @natchembio.nature.com www.nature.com/articles/s41...
nature.com
ZBTB11 depletion targets metabolic vulnerabilities in KRAS inhibitor-resistant PDAC - Nature Chemical Biology
Depletion of a transcriptional factor ZBTB11 using molecular glue degraders can overcome oxidative-phosphorylation-mediated KRAS inhibitor resistance in pancreatic ductal adenocarcinoma with low acute...
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Leslie Rissler @ljrissler.bsky.social · 08/08/2025
“This Executive Order is nothing short of obscene," said Ranking Member Zoe Lofgren (D-CA). "In what world does Donald Trump think that Americans want political appointees – who, need I remind the President, are unelected bureaucrats – making decisions on what science gets funded?”
democrats-science.house.gov
Ranking Member Lofgren Calls Trump Out for Corrupt Executive Order Requiring Political Appointees to Approve Federal Grants | House Committee on Science, Space and Technology
The House Committee on Science, Space and Technology
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Max Kozlov @maxkozlov.bsky.social · 31/07/2025
The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.
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Matt Pratt @mattrpratt.bsky.social · 31/07/2025
35 non airport-only visits
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Meg Tirrell @megtirrell.bsky.social · 29/07/2025
A major NIH grant to study ways to restore hearing was terminated by the Trump administration bc it was awarded through a DEI initiative—to a researcher who qualified bc of his own hearing loss www.cnn.com/2025/07/29/h... @manorlaboratory.bsky.social
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Don Moynihan @donmoyn.bsky.social · 29/07/2025
This piece in Science: *confirms that the push for multi-year funding is coming from White House, against NIH wishes *White House is deliberately slowing spending already appropriated to then cut it via rescission www.science.org/content/arti...
NIH also faces a more immediate threat: the loss of money it has already been awarded. Trump policies have slowed agency spending so much that Berg estimates the agency is at least $6 billion behind in its spending. As a result, a large portion of its $49 billion budget could go back to the U.S. Department of the Treasury when the fiscal year ends on 30 September.

In principle the administration could claw back the money in a so-called rescission, like the one that recently cut billions from global health and public broadcasting. In their 25 July letter to the Office of Management and Budget (OMB), the 14 Republican senators wrote that “suspension of these appropriated funds – whether formally withheld or functionally delayed — could threaten Americans’ ability to access better treatments and limit our nation’s leadership in biomedical science.”
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GlycoNet @glyconet.bsky.social · 10/07/2025
🧬Power your research with GlycoNet Integrated Services’ Molecular Glycobiology node at the ‪@ualberta.bsky.social‬ Offering: Custom cell & mouse models (CRISPR, transgenics) Siglec-Fc protein production Cell engineering & expert support Explore more services: canadianglycomics.ca/services/
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Ben Schumann @drglycoben.bsky.social · 25/06/2025
🔥 Job alert! We are looking for an enthusiastic PhD candidate in the new Chemical Glycobiology Lab at @tudresden.bsky.social! Master in Chem or similar, experience in organic chem including chemoenzymatic, and most importantly: enthusiasm! Deadline 8th July: www.verw.tu-dresden.de/StellAus/ste...
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Matt Pratt @mattrpratt.bsky.social · 24/06/2025
Humans don't reproduce long enough to put evolutionary pressure against amyloids. Other animals? We find older-living animals (whales, crocs, etc.) have synuclein that is less prone to aggregation (in vitro) than shorter-lived animals, independent of evolutionary distance: shorturl.at/MtgcR
chemistry-europe.onlinelibrary.wiley.com
α‐Synuclein Sequences from Long‐Lived Animals Display Generally Diminished Aggregation Compared to Shorter‐Lived Animals Including Humans.
The overall process of protein aggregation from soluble species to amyloid fibrils is toxic to neurons and can propagate along neuronal connections in ways that potentially explain the pathological p...
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@LaBonneLaB @labonnelab.bsky.social · 03/06/2025
Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post. www.washingtonpost.com/opinions/202...
washingtonpost.com
Opinion | Universities and the government: Which needs the other more?
From public health to high-tech innovation, universities are the workhorses of national progress.
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Wajahat Ali @wajali.bsky.social · 19/05/2025
This should be bigger news, no? www.yahoo.com/news/trump-s...
yahoo.com
Trump slashed US cancer research by 31 percent: Senate report
US President Donald Trump's administration cut cancer research funding by 31 percent in the first three months of 2025 compared to the same period last year, according to a Senate report released Tues...
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Aaron Rupar @atrupar.com · 14/05/2025
DeLAURO: Are you planning to break the law by impounding appropriated funds? RFK Jr: If you appropriate the funds, I'm going to spend them D: We have! You're cutting the NIH by $18b. Congress appropriated those funds. How can you justify cutting billions from the biomedical research budget?
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Sam Stein @samsteindc.bsky.social · 13/05/2025
Bernie Sanders' office has put out a report this morning on Trump's NIH cuts: "Trump officials effectively cut $2.7 billion in [NIH] funding in the first three months of 2025 – including a 31 percent cut to cancer research through March, compared to the same timeframe last year."
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Science Magazine @science.org · 09/05/2025
Exclusive: National Science Foundation staff were told today that the agency’s 37 divisions—across all eight directorates—are being abolished and the number of programs within those divisions will be drastically reduced.
scim.ag
Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions
Changes seen as a response to presidential directives on what research to fund
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Shannon Macauley @macauleylab.bsky.social · 05/05/2025
Amplifying this. NIH money not used by end of summer is gone. I've had a new R01 pending for months now, the award is prepared (according to ERA commons), what steps are left before the NOGA and funds released? Feel like many grants are being slow rolled before they are then not funded.
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Melody Schreiber @melodyschreiber.com · 06/05/2025
This is a great piece. Bhattacharya insisted that the reporter not "write about rumors" because "it spreads panic.” Hours later, those very leads were confirmed. www.science.org/content/arti...
science.org
‘It’s been a tough period’: NIH’s new director speaks with Science
Jay Bhattacharya discusses staff morale, grant cuts, and “rumors”
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Geoff Hutchison @geoffhutchison.net · 06/05/2025
The AAU, the APLU, and ACE and a bunch of named universities (including @cmu.edu) filed a challenge to the arbitrary cut of indirect costs at the National Science Foundation (As I write two NSF proposals...) #SaveNSF #SaveScience www.aau.edu/newsroom/pre...
aau.edu
Statement of AAU, the APLU, and ACE Regarding their Legal Challenge to the National Science Foundation’s Cut to Critical Research That Strengthens America | Association of American Universities (AAU)
This is a statement of the Association of American Universities, Association of Public & Land-Grant Universities, and American Council on Education regarding their legal challenge to the administratio...
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Matt Pratt @mattrpratt.bsky.social · 06/05/2025
Heard this story in person from @laurakiessling.bsky.social at a conference and glad to see it out. I really love approaches where I get to say to myself “man I wish I had thought of that”…simple and elegant.
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 06/05/2025
The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n
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Dan Garisto @dangaristo.bsky.social · 01/05/2025
BREAKING: NSF has frozen all grant funding, as of yesterday. It's unclear when they will resume funding awards, or why the pause has been put in place. www.nature.com/articles/d41...
nature.com
Exclusive: NSF stops awarding new grants and funding existing ones
US science funder also plans to screen grant applications for compliance with ‘agency priorities’.
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Ardem Patapoutian @ardemp.bskyverified.social · 03/05/2025
The president is recommending a 40% cut to next year’s NIH budget. This would be disastrous for our nation’s health and economy. Please contact your representatives, especially if they are Republicans, and tell them why this cannot happen. An easy option: 5calls.org
5calls.org
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
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Charles Logan @charleswlogan.bsky.social · 02/05/2025
FYI: The Spencer Foundation, Kapor Foundation, The William T. Grant Foundation, and the Alfred P. Sloan Foundation have collaborated to offer $25K rapid response grants. "This rapid response bridge funding opportunity is for scholars and teams whose grants have recently been cancelled by NSF."
spencer.org
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
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Gregg Gonsalves @gregggonsalves.bsky.social · 01/05/2025
I am late to this but @lastweektonight.com is doing better journalism on the Trump-induced crisis in American public health than most other "real" mainstream media outlets. Watch it, all of it. #RFKMustGo. youtu.be/8H34jcpEsFs?...
youtu.be
RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)
YouTube video by LastWeekTonight
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All In with Chris Hayes @allinwithchris.bsky.social · 24/04/2025
"So who voted for this? I personally don't remember Donald Trump's campaign promise to cut breast cancer research and to make menopause harder for American women,” says Chris Hayes on the Trump admin gutting the first and largest women’s health study.
youtube.com
‘Who voted for this?’: Trump guts first and largest women’s health study
YouTube video by MSNBC
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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025
ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n
media.tenor.com
the word alert is in a purple circle
ALT: the word alert is in a purple circle
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Gabriel Bosslet @gbosslet.bsky.social · 23/04/2025
Well the NIH has cancelled the Women's Health Initiative, the largest study of women in history It has been running continuously since 1991 and has provided massive key knowledge about diseases in women Unreal www.science.org/content/arti...
science.org
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
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Iain Wilson @iainwilsonwien.bsky.social · 22/04/2025
Nick Riley receives one of the Biochemical Society Early Career Research Awards for 2026. Congratulations to @nmriley.bsky.social www.biochemistry.org/grants-and-a...
biochemistry.org
Past Award Winners
Past Award Winners
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Matt Pratt @mattrpratt.bsky.social · 18/04/2025
I'm struggling...
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Roger Freedman @rogerfreedman.bsky.social · 16/04/2025
Kudos to Seth Rogen for speaking truth to power! 🧪
independent.co.uk
Seth Rogen’s Trump joke cut by awards ceremony
Actor’s cut joke made co-presenter Edward Norton ‘uncomfortable’
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steveusdin.bsky.social @steveusdin.bsky.social · 17/04/2025
The leaked Trump administration 2026 HHS budget is sickening. If enacted, it will destroy American science. NIH budget slashed by 40%. The 15% overhead for universities baked into law. Ill-conceived reorganization of NIH institutes.
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