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Pablo J. Sáez

@pjsaez.bsky.social
1.7K followers 519 following 292 posts

Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat. I love to study how cells walk & talk. PI of the @cellcommlab.bsky.social #CellMigration #CellComm #calciumsignaling #organelles 🧪🔬

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Reposted by Pablo J. Sáez
Jean Léon Maître @maitrejl.bsky.social · 6h
📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr
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Nobel Prize @nobelprize.org · 05/10/2026
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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Reposted by Pablo J. Sáez
Michael Way @drmichaelway.bsky.social · 02/10/2026
Looking for a PhD? @crick.ac.uk PhD applications for next year are open. 4 year program with lots of outstanding projects on offer. If you are interested in viral host interactions, cytoskeleton, cell bio, live cell imaging - see Way lab project + video. plz repost www.crick.ac.uk/careers-and-...
crick.ac.uk
PhD student positions
PhD projects for the 2027 Crick PhD programme.
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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 02/10/2026
Happy #FluorescenceFriday. Single immune cell migration is fascinating. But these cells can also behave like a coordinated collective, like 🐝 from a hive. I captured some embryonic myeloid cells (🔴) displaying swarming behaviour in a migrating ectoderm cell sheet (🔵), like neutrophils in our body!
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Reposted by Pablo J. Sáez
Filipe De Vadder @filipedevadder.bsky.social · 30/09/2026
🚨PREPRINT ALERT How different are males and females? In physiology we mostly treat that as a fixed property of a species, something to control for. In mice, we found it is not fixed at all. It depends on what the animal ate while growing up.
biorxiv.org
Juvenile protein restriction compresses sexual dimorphism in mice
Sexual dimorphism is canonically understood as a fixed adult trait, scaled by gonadal hormones at puberty, but whether its magnitude is shaped earlier in life by juvenile nutrition during the post-wea...
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Reposted by Pablo J. Sáez
Elena Scarpa & The Squeezable Cells Lab @squeezycellslab.bsky.social · 29/09/2026
Call for abstracts: the UK Cell Motility Club is back! Keynote speaker : Caren Norden 🐠 Fantastic early career talk opportunity and lovely community! Register here: forms.cloud.microsoft/e/zNNCMfD5jF
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Reposted by Pablo J. Sáez
FocalPlane @focalplane.bsky.social · 30/09/2026
While we’ve heard that watching cell blebs (like watching larva lamps) can be relaxing, we think that @ankita13jha.bsky.social’s talk from our #CellMigration webinar will leave you feeling excited about #science & running to your #microscope! Full video @ focalplane.biologists.com/2026/09/25/f...
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Pablo J. Sáez @pjsaez.bsky.social · 30/09/2026
Two cakes...two "last pieces"... I guess only @isabel-stoetzel.bsky.social will understand, bc I don't 😅🤷🏽‍♂️
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Reposted by Pablo J. Sáez
Saez-Rodriguez Group @saezlab.bsky.social · 29/09/2026
Happy to see the peer-reviewed version of SpaCEy now out: 📄 Published paper: www.nature.com/articles/s41... 💻 Code: github.com/saezlab/SpaCEy
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026
Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share
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Pablo J. Sáez @pjsaez.bsky.social · 28/09/2026
If you would be reading one of my papers before publication, you would be _loving_ it 😜
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Pablo J. Sáez @pjsaez.bsky.social · 26/09/2026
Happy to come back to Turku anytime soon for a longer visit ;)
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Pablo J. Sáez @pjsaez.bsky.social · 25/09/2026
Andy's @aaandmoore.bsky.social diplomacy in his engagement are a example of composure. I would have become at least like The Merovingian in The Matrix... @christlet.bsky.social, if this bs doesn't change, then what the next round will look like: The Nikon competition for AI hallucination?
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Reposted by Pablo J. Sáez
Isabel Stötzel @isabel-stoetzel.bsky.social · 25/09/2026
What a fantastic visitor! Thanks Pablo @pjsaez.bsky.social @cellcommlab.bsky.social for visiting Turku (organised by @mattilalab.bsky.social )! Especially, it was a pleasure to hear your experiences and thoughts during the career/science session. Thanks for taking the time and sharing your opinion!
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FocalPlane @focalplane.bsky.social · 25/09/2026
ICYMI: the recording of our second webinar on emergent models and quantitative analysis of cell migration is now available. 🔬🎥Check it out to see talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social focalplane.biologists.com/2026/09/25/f...
focalplane.biologists.com
FocalPlane features... cell migration recordings with Ankita Jha, Raphaël Clément and Katrina Velle - FocalPlane
FocalPlane features... cell migration recordings with Ankita Jha, Raphaël Clément and Katrina Velle - News
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Pablo J. Sáez @pjsaez.bsky.social · 25/09/2026
Thanks @isabel-stoetzel.bsky.social it was great to visit you all ! Especial tks to @mattilalab.bsky.social for the invitation, & the great Turku community for discussions that could go for hours ;) @johannaivaska.bsky.social @alankolab.bsky.social @ivaskalab.bsky.social @guijacquemet.bsky.social
ilalab.bsky.social
Bluesky
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Valeria Venturini @valeriaventurini.bsky.social · 22/09/2026
In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫 Here all the info ibecbarcelona.eu/predoctoral-...
ibecbarcelona.eu
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Pablo J. Sáez @pjsaez.bsky.social · 21/09/2026
If I ever manage to make an optotool, however unlikely, I'll call it OptoBad !! (And request to have a similar graphical abstract)
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Pablo J. Sáez @pjsaez.bsky.social · 21/09/2026
Duh, is the best graphical abstract you have ever seen about opto tools? 😉
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Jan Lammerding - Lab @lammerdinglab.bsky.social · 21/09/2026
Looking for a faculty position combining research in fundamental cell and molecular biology with therapeutic discovery? Join our amazing faculty at the @weillinstitute.bsky.social at Cornell University in Ithaca, New York. academicjobsonline.org/ajo/jobs/32657 Apply by Nov. 15! Please share!
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Pablo J. Sáez @pjsaez.bsky.social · 20/09/2026
#CellCommunication + #CalciumSignaling What else can you ask for?
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Pablo J. Sáez @pjsaez.bsky.social · 19/09/2026
I couldn't miss it. It was great to see you get such a recognition, kudos again Sara ! Also I had a lot of fun with @katemiro.bsky.social, as always 😉
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Pablo J. Sáez @pjsaez.bsky.social · 18/09/2026
#Mechanobiology rules! Today, it's not only Chile's independence day🇨🇱😋 ...but also Sara Wickström @sarawickstrom.bsky.social is getting the Körber Prize 👏🏽👏🏽👏🏽 for being a "curiosity's junkie" 😂 Of note, Kate photobombing is top @katemiro.bsky.social @focalplane.bsky.social @koerber-ip.bsky.social
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Pablo J. Sáez @pjsaez.bsky.social · 16/09/2026
Wanna see blebs dancing & new models of #CellMigration? Join us tomorrow to see the great talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social Thu 17 Sep. at 15:00 BST / 16:00 CEST Register: focalplane.biologists.com/2026/09/03/f... @focalplane.bsky.social
nt.bsky.social
Bluesky
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FocalPlane @focalplane.bsky.social · 15/09/2026
Don’t miss the second webinar in our new series on cell migration, featuring talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social. 🗓️Thursday 17 September at 15:00 BST For more info and to register: focalplane.biologists.com/2026/09/03/f...
focalplane.biologists.com
FocalPlane features... cell migration webinar 2 - FocalPlane
FocalPlane features... cell migration webinar 2 - News
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Seema Grewal @seemagrewal.bsky.social · 16/09/2026
Working on #cellmigration? Join us online tomorrow for the second webinar in our series, hosted by @pjsaez.bsky.social and @valeriaventurini.bsky.social
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Pablo J. Sáez @pjsaez.bsky.social · 15/09/2026
Relieved to remember that after 1 M versions + last minute changes somehow, somewhere there is light @ the end of the tunnel... Grateful for the work of my @cellcommlab.bsky.social Whenever is ready we'll post it to receive comments from the community 😉 Tks 4 existing @biorxivpreprint.bsky.social 🧪🔬
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Pablo J. Sáez @pjsaez.bsky.social · 14/09/2026
I use it every single semester for my lectures. It's a beautiful experiment that never gets old... Thanks for that @baym.lol , Tami and Roy
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Reposted by Pablo J. Sáez
Journal of Cell Biology @jcb.org · 11/09/2026
Gourkanti et al. @neal-lab.bsky.social show that the rhomboid protease Rhbdl2 restrains #macrophage recruitment & wound repair in #zebrafish, positioning Rhbdl2 as a potential brake on macrophage-driven repair rupress.org/jcb/article/... #Migration #motility #Immunology
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Teresa Rayon @trayon.bsky.social · 12/09/2026
‼️ Postdoc position open. We study how protein metabolism controls time. If you’re excited by this question, we’d love to hear from you! We’re looking for a motivated & collaborative researcher with a strong track record. 📅 30 September 2026 📢 Please share Apply here 👇👇
babraham.current-vacancies.com
Postdoctoral Research Scientist - Babraham
The lab investigates the molecular mechanisms that control biological timing in mouse and human stem cells (Azzi & Rayon, Curr Opinions 2024; Nakanoh et al., Dev Cell 2026). The central aim of this ex...
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FocalPlane @focalplane.bsky.social · 10/09/2026
📢One week to go! Join us on Thursday 17 September at 15:00 BST (UTC+1) for our webinar on new models for studying cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. You’ll hear talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social.
focalplane.biologists.com
FocalPlane features... cell migration webinar 2 - FocalPlane
FocalPlane features... cell migration webinar 2 - News
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Max-Planck-Gesellschaft @maxplanck.de · 09/09/2026
We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack
Call for independent Max Planck Research Groups
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Triangle Cytoskeleton Meeting @tricytomeet.bsky.social · 04/09/2026
LAST CALL FOR POSTER ABSTRACTS! We are just over 2 weeks away from the 2026 Triangle Cytoskeleton Meeting at the William and Ida Friday Center on Sept. 21st. Submit your abstract by Monday, Sept. 7th for the opportunity to present a poster. Registrations will remain open until Sept. 14th.
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Pablo J. Sáez @pjsaez.bsky.social · 07/09/2026
hahaha if you are ready ! we can have a chat, any time ;)
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Pablo J. Sáez @pjsaez.bsky.social · 07/09/2026
Wow !! Congratulations @anhhle2702.bsky.social !!
static.klipy.com
Fire Elmo
ALT: Fire Elmo
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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 07/09/2026
Very happy to share my postdoc paper is out now in @natcellbio.nature.com titled "Tissue flow acts as a guidance cue for immune cell polarization and directional migration". If you love imaging and immune cells, this is for you! #microscopymonday www.nature.com/articles/s41... A 🧵: 1/n
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Tamas Nagy @tamasnagy.com · 06/09/2026
Even with all the advancements in automated cell tracking getting us to 90%+ accuracy...that's still a lot of broken tracks over long movies! Our brains are pretty good at this so I made Vizsla 🐕, a little @napari.org plugin, to help you fix your tracks manually. 👉 pypi.org/project/napa...
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Pablo J. Sáez @pjsaez.bsky.social · 06/09/2026
This is why we love #CellMigratuon ! This beautiful story is now out, very interesting role for RhoA and also the cover, Neutrophils on the 'Rho'ad Congrats to all authors, especially to former colleagues and friends Full @science.org www.science.org/doi/10.1126/...
science.org
Adaptive motility enables neutrophils to rapidly navigate confined capillaries
Neutrophils maintain migration speed in confined capillaries through adaptive actomyosin remodeling.
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Katrina Velle @katrinavelle.bsky.social · 03/09/2026
I'm very excited to be included in this lineup! Thanks @pjsaez.bsky.social and @valeriaventurini.bsky.social for organizing!
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FocalPlane @focalplane.bsky.social · 03/09/2026
We are excited to invite you to the second webinar in our cell migration series. In this webinar, we focus on new models for studying cell migration with talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social. More info⤵️: focalplane.biologists.com/2026/09/03/f...
FocalPlane features... emergent models and quantitative analysis of cell migration
Thursday 17 September, 15:00-16:30 BST (UTC+1) 
Organised by Organised by Pablo J. Sáez and Valeria Venturini
FocalPlane logo
Picture of Ankita Jha (National Institutes of Health, USA)
Decoding bleb driven signaling in cancer disease progression
Picture of Raphaël Clément (L’Institut de Biologie du Développement de Marseille (IBDM), France)
Navigating without neurons or muscles: Locomotion in Trichoplax
Picture of Katrina Velle (University of Massachusetts Dartmouth, USA)
Naegleria amoebae seek confinement and crawl persistently through narrow spaces
#FocalPlaneFeatures
focalplane.biologists.com
Image of Naegleria.
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Pablo J. Sáez @pjsaez.bsky.social · 02/09/2026
Another year is gone & I grow old and proud of the work of my team @cellcommlab.bsky.social To celebrate the 6th labversary, we did the best we can do: we submitted...now to cross fingers & to press F5. OK, to celebrate we also had pizza as tradition dictates ;) #CellMigration & pizza lovers 🧪🔬
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Pablo J. Sáez @pjsaez.bsky.social · 26/08/2026
Hi Ankita, I sent you an email. Did you get it? Pls let me know 😉
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Pablo J. Sáez @pjsaez.bsky.social · 19/08/2026
Blebbing cell under confinement?
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Caetano Reis e Sousa @reisesousalab.bsky.social · 19/08/2026
Hope you enjoy this short piece, which came out yesterday. Some thoughts I’ve been musing on for a while about why adaptive immunity evolved. Read it for free at rdcu.be/fAO5P
rdcu.be
Why adaptive immunity?
Nature Reviews Immunology - Adaptive immunity is indispensable to vertebrates, yet most living organisms defend themselves perfectly well without it. Here, I ask why somatically diversified antigen...
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Isabella Backman @izzybackman.bsky.social · 19/08/2026
For @science.org , I wrote about brain-eating amoeba 🦠 and fascinating new research led by @katrinavelle.bsky.social which could help explain how the usually harmless pond-dweller ends up in the brain. www.science.org/content/arti...
science.org
‘Brain-eating amoeba’ appears to love crawling into narrow spaces
Claustrophilic behavior may help Naegleria fowleri find food—and accidentally travel up the human nasal cavity
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Pablo J. Sáez @pjsaez.bsky.social · 18/08/2026
#cytoskeleton So, there is a small (very small) 9-aa motif that is an evolutionary conserved anchor to actin. It's named: short linear actin filament-binding motif (SFM), and it's *the same* found in LifeAct ! Full: www.nature.com/articles/s41... @natcellbio.nature.com @cellclub.bsky.social 🧪🔬
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Ivan Zanoni @lozanzi.bsky.social · 14/08/2026
#DAMPsPower!! Excited to share the 💥new 💥 review @ Science Immunology that @marcodigioia & I wrote about the immunological activities played by host-derived oxidized lipids in controlling infections & tumorigenesis! doi.org/10.1126/scii...
doi.org
Regulation of inflammation by oxidized lipids
Lipids generated by oxidative stress and their effects on immunity and cancer are reviewed.
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Biozentrum, University of Basel @biozentrum.unibas.ch · 10/08/2026
Ready for the next step in your scientific career? Apply now for a fully funded Biozentrum PhD Fellowship and explore a wide range of research fields before choosing your PhD lab. 🧪 Applications for the current call are open until October 18, 2026. More information 👇
biozentrum.unibas.ch
Biozentrum PhD Fellowships
Share your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the sought after B...
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Journal of Cell Science @jcellsci.bsky.social · 05/08/2026
We invite you to submit your latest research to our upcoming special issue: Proteostasis. This issue will be coordinated by two of our Academic Editors: Pedro Carvalho and Tamotsu Yoshimori. journals.biologists.com/jcs/pages/pr...
Call for paper | Special Issue
Proteostasis
Editors: Pedro Carvalho and Tamotsu Yoshimori
Submission deadline: 2 November 2026 
Journal of Cell Science logo
Confocal microscopy image of A549 cells stably expressing RFFL–EGFP (cyan), labelled for mitochondria (stained with MitoTracker Red CMXRos; orange) and lipid droplets (stained with HCS LipidTOX; green). This image looks a little like two owl eyes!
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Pablo J. Sáez @pjsaez.bsky.social · 05/08/2026
Nice work! It'll go directly to the reference list of a review we are writing. Thanks for letting our sentence go from pure speculation to new knowledge 👌🏽
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