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Quantitative microscopy of microorganisms increasingly produces large, multidimensional datasets, yet their analysis often depends on fragmented workflows spanning file conversion, segmentation, quali...

The slow growth displayed by Mycobacterium tuberculosis has been historically associated with pathogen’s persistence and drug tolerance. Unexpectedly, here the authors identify a rare subpopulation of...

Here, the authors report metabolic activation as a potential antimicrobial strategy against Mycobacterium tuberculosis. They show that supra-physiological activation of L-histidine biosynthesis r...

This review presents a comprehensive overview of Type IV Secretion Systems (T4SSs), focusing on their structural, functional, and evolutionary diversity ac

Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

Noise in bacterial stress responses is often dismissed as mere randomness. While true stochasticity exists, much variation reflects hidden variables—cell state, history, and microenvironment—that are ...

Names matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad...

Working for us We’re always looking for talented and motivated people to work as part of our close-knit team. Roles range from editorial to production, marketing to event co-ordination, HR to accounts...

Sterol-rich microdomain accumulation at the MCV is crucial for Mm-induced damage and infection in D. discoideum and BV-2 cells.

Here, the authors show that Mycobacterium tuberculosis manipulates lipid metabolism to overcome host restriction, by remodelling its lipidome and utilising host lipids as an alternative phosphate sour...

Developing effective accessible vaccines to end tuberculosis worldwide. Combining immunoengineering, molecular microbiology & systems biology at MIT.

Developmental biology

We are looking for an enthusiastic and motivated PhD candidate to join Dr. Catalin Bunduc’s team in the Molecular Microbiology Section of the Amsterdam Institute for Life and Environment (A-LIFE).