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phoeberice.bsky.social

@phoeberice.bsky.social
94 followers 44 following 92 posts

Interested in mobile DNA, molecular machines, structural biology

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Reposted by @phoeberice.bsky.social
Quanta Magazine @quantamagazine.org · 23/09/2026
“Jumping genes” can cut and paste themselves into new locations in the genome. But they’re more than parasites or genetic junk. www.quantamagazine.org/how-virus-li…
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Nicolas Hénin @nicolashenin.net · 17/09/2026
Nice campaign by the Norwegian Consumer Council about the declining lifespan of products. Enjoy!
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phoeberice.bsky.social @phoeberice.bsky.social · 17/09/2026
Postdoctoral fellowship to come to U Chicago biologicalsciences.uchicago.edu/research/chi...
biologicalsciences.uchicago.edu
Chicago Fellows
The Chicago Fellows Program is an internationally competitive postdoctoral fellowship program to support the career advancement of truly exceptional and creative scientists in the biological and biome...
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Artologica aka Michele Banks @artologica.net · 14/09/2026
Attention #sciart people! The ASM agar art contest is open. Deadline is October 21 🧪🧫
asm.org
ASM Agar Art Contest | Contest Details
Have you ever seen art created in a petri dish using living, growing microorganisms? That's agar art! ASM's annual Agar Art Contest is a chance for you to use science to show off your creative skills.
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Drummond Lab @drummondlab.bsky.social · 08/09/2026
We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Join us! apply.interfolio.com/191981 bcmb.uchicago.edu
A picture of the University of Chicago campus, with downtown Chicago in the distance and Lake Michigan on the horizon. The campus's central quad is pictured, a classical collegiate quad with paths and old trees and stone architecture. It's really pretty and I love it.
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Jay Troyer @gr8flbluejay.bsky.social · 07/09/2026
Criselda Vasquez, American, The New American Gothic, 2017, oil on canvas, 72 x 48 in, private collection The artist's father, portrayed in the painting, was kidnapped by ICE on 31 March 2026
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phoeberice.bsky.social @phoeberice.bsky.social · 07/09/2026
A walk in the windy city today
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phoeberice.bsky.social @phoeberice.bsky.social · 03/09/2026
Interesting - would love to know exactly what those small S recombinases are doing!
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Elle Cordova @ellecordova.bsky.social · 03/09/2026
Rough Draft vs Final Draft
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Cassandra Hayne @cassandrahayne.bsky.social · 02/09/2026
The Department of Biochemistry and Molecular Biology at #UChicago is looking for a new junior faculty member to join us. If you or someone you know would be a good fit, please apply or encourage them to apply! apply.interfolio.com/191981
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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phoeberice.bsky.social @phoeberice.bsky.social · 01/09/2026
Deeply saddened by news of the passing of our friend and colleague Nancy Schwartz. Beyond her scientific accomplishments, her tireless efforts in providing training opportunities for generations of young scientists were simply amazing. Shoes that I fear cannot be filled.
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Mike Keesey @tmkeesey.bsky.social · 30/08/2026
We are getting VERY close 13,000 silhouettes! www.phylopic.org/images
phylopic.org
All Silhouette Images on PhyloPic
Browse all the free silhouette images in PhyloPic.
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uchichemistry.bsky.social @uchichemistry.bsky.social · 28/08/2026
We’re hiring! The University of Chicago Department of Chemistry is seeking a Senior Instructional Professor to join our instructional team. academicjobs.uchicago.edu/positions/19...
academicjobs.uchicago.edu
Academic Jobs | The University of Chicago
The University of Chicago is a private, nondenominational, culturally rich and ethnically diverse coeducational research university located in Hyde Park, Chicago.
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phoeberice.bsky.social @phoeberice.bsky.social · 27/08/2026
We're all disgusted - but where is the incentive for honesty in these catalogs? At the very least, labs that paid for falsely advertised antibodies should get their money back! www.nature.com/articles/d41...
nature.com
More than 18,000 questionable images found in antibody catalogues of 15 companies
Science sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.
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Anthony Vecchiarelli @cellforganized.bsky.social · 26/08/2026
My MCDB Dept is hiring, again! Assistant Professor Faculty Search. Please Repost! Applications Due Oct 1st We welcome applications from all areas of cellular/molecular biology in prokaryotes, plants, and animals. More information can be found HERE: jobs.sciencecareers.org/job/679540/a...
jobs.sciencecareers.org
Assistant Professor - Ann Arbor, Michigan job with University of Michigan - Molecular, Cellular and Developmental Biology | 679540
UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS   The Department of Molecular, Cellular, and Developmental B...
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phoeberice.bsky.social @phoeberice.bsky.social · 25/08/2026
This is funny ... but ... many students, especially ones who aren't native speakers of English, stress out over these nuances. So useful!
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phoeberice.bsky.social @phoeberice.bsky.social · 24/08/2026
In what way does this make America great???
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Ákos T Kovács @evolvedbiofilm.bsky.social · 21/08/2026
Bacterial nanotubes extend from a tubeosome organelle to establish an intercellular bridge bioRxiv by @mkguria24.bsky.social et al from Sigal Ben-Yehuda www.biorxiv.org/content/10.6...
biorxiv.org
Bacterial nanotubes extend from a tubeosome organelle to establish an intercellular bridge
Bacterial nanotubes are widespread intercellular membranous bridges mediating molecular exchange among neighboring cells, yet their formation and dynamics remain largely unexplored. By combining live-...
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Karolin Luger @nucleosomepolice.bsky.social · 19/08/2026
upcoming @hhmi-science.bsky.social competitions y'all!
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Mark O. Martin @markowenmartin.bsky.social · 13/08/2026
Perspective is critical. Eukaryocentrism and humancentric views are so limiting.
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Kihara Laboratory @kiharalab.bsky.social · 13/08/2026
📢 New paper in Current Protocols! 🧬 We present practical protocols for ComplexModeler and CryoZeta, deep learning tools for modeling protein–DNA/RNA complexes from cryo-EM maps, freely available through EMSuite. 🔬💻 📄 doi.org/10.1002/cpz1... em.kiharalab.org
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phoeberice.bsky.social @phoeberice.bsky.social · 12/08/2026
Yikes! And Chicago has had so much rain that the grass in the parks is emerald green at a time when it when it is usually turning a bit crispy.
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Ran Blekhman @blekhman.bsky.social · 09/08/2026
Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9zv3rj...
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Bryan Dickinson @chembiobryan.bsky.social · 11/08/2026
Big faculty search in chemical biology, campus-wide, at University of Chicago! Come be my colleague! This is a special place! apply.interfolio.com/190752
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Landon Getz @landongetz.bsky.social · 06/08/2026
DNA glycosylases are repair enzymes, essential to all cellular life. They find chemically damaged bases and remove them so DNA can be repaired. Today in Nature Microbiology, we show bacteria have repeatedly repurposed them into antiviral immune systems 🧵 www.nature.com/articles/s41...
nature.com
Antiviral defence is a conserved function of diverse bacterial DNA glycosylases - Nature Microbiology
DNA glycosylases, typically used for DNA repair, can also protect bacteria against phages that would otherwise evade host immunity by incorporating modified bases into their genomes.
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 05/08/2026
A hierarchical regulatory cascade defines the temporal window of natural transformation in Staphylococcus aureus www.biorxiv.org/content/10.64898/20…
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Craig Kaplan @triggerloop.bsky.social · 03/08/2026
This is extremely cool and makes scientific sense. Anti-retrotransposon editing as precursor to mechanism for antibody diversification
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Nucleic Acids Research @narjournal.bsky.social · 31/07/2026
📣NAR is recruiting a new Executive Editor!📣Seeking an established researcher with expertise in RNA biology and translation mechanisms to help shape the journal's scientific direction, oversee peer review, and support its growth. Apply by 30 Sept 2026: academic.oup.com/nar/pages/ex...
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Jeremy Berg @jeremymberg.bsky.social · 24/07/2026
@dereklowe.bsky.social lets loose again (and I am still here for it). www.science.org/content/blog... 1/2
science.org
The Assault On Science Funding Continues
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phoeberice.bsky.social @phoeberice.bsky.social · 22/07/2026
Thank you! Our medically-biased system left me completely ignorant of such fascinating organelles!
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phoeberice.bsky.social @phoeberice.bsky.social · 22/07/2026
Great memories of that museum from my youth! love the design.
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Miloš Tišma @tismaa.bsky.social · 21/07/2026
I'm happy to share the first paper from my postdoc work: www.biorxiv.org/content/10.6... How does RecA find one homologous sequence in an entire chromosome -and what turns that encounter into a repair-competent one? We find that DNA topology is the gatekeeper !! 1/10
biorxiv.org
Chromosome topology gates productive RecA homology search
In homologous recombination, DNA repair depends on recombinase filaments finding homologous templates on chromosomes whose topology is continually remodeled by replication and transcription. How dynam...
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Ryan Marino, MD @ryanmarino.bsky.social · 27/08/2025
CDC is no longer surveilling outbreaks caused by campylobacter, cyclospora, listeria, shigella, vibrio and Yersinia. What could go wrong?
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phoeberice.bsky.social @phoeberice.bsky.social · 08/07/2026
I certainly agree about using AI to fake understanding of somebody's work! But ... some students get astoundingly anxious about composing email to profs. We could be more pro-active in explaining the "obvious" (e.g. how to strike a balance between Victorian formality and teenage slang).
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phoeberice.bsky.social @phoeberice.bsky.social · 02/07/2026
My apartment building's idea of recycling, sigh.
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phoeberice.bsky.social @phoeberice.bsky.social · 29/06/2026
Go Sarah! A good argument in support of stable funding for basic science. And great to see one of the Rice lab's first undergraduates doing such cool stuff.
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David Ho @davidho.bsky.social · 23/06/2026
This amount would fund the US National Science Foundation for a decade. 🧪
apnews.com
Pentagon seeks $80 billion from Congress for Iran war
The Pentagon has told lawmakers it needs roughly $80 billion, mostly to cover the cost of the war in Iran.
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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 16/06/2026
Barbara McClintock was born #OTD in 1902. 🧪 🌽 McClintock, who spent most of her career at Cold Spring Harbor Laboratory, won a Basic Medical Research Lasker in 1981 for the discovery of transposons, genetic elements that can move from one location to another: ow.ly/hVNI50Jvkql #WomenInSTEM
Barbara McClintock in her later years, wearing a purple sweater and beige jacket, holding a multicolored ear of corn outdoors near greenery.Barbara McClintock in her later years conversing with a student in a dense cornfield.A black and white photograph of a young Barbara McClintock in a lab coat working with microscope slides and a microscope in a vintage laboratory setting.
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Pablo Ivan Nikel @pabnik.bsky.social · 11/06/2026
Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida by Javier Hernández @labnikel.bsky.social #SyntheticBiology #MetabolicEngineering #GeneticCircuit #OpenAccess academic.oup.com/nar/article/... @narjournal.bsky.social
academic.oup.com
Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida
Abstract. Genetic circuits for model bacteria often perform poorly in non-canonical hosts, limiting the deployment of regulatory programs in industrially r
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The EMBO Journal @embojournal.org · 10/06/2026
CapK is a bacterial DNA damage-activated kinase that phosphorylates transcriptional repressor CapS to control adjacently-encoded anti-phage immune pathway genes in response to a universal stress signal, DNA damage @kevincorbett.bsky.social and colleagues link.springer.com/article/10.1...
link.springer.com
A DNA damage-activated kinase phosphorylates a transcriptional repressor to control bacterial immune pathway expression - The EMBO Journal
Bacteria encode numerous stress-response pathways that protect their hosts against both internal and external threats. A key question is how these pathways are regulated, especially anti-phage immune ...
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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 06/06/2026
Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com​​​​​​​​​​​​​​​​ 🌐 search.foldseek.com/folddisco
nature.com
Structural motif search across the protein universe with Folddisco - Nature Biotechnology
Folddisco enables protein structural motif search in million scale databases.
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Michael D. Green, PhD @michaeldgreen.phd · 28/05/2026
President of MIT not mincing words today in @statnews.com www.statnews.com/2026/05/27/s...
So let me say it as clearly as I can: Without basic scientific research, supported by the kind of farsighted public investment that allows large-scale, undirected, curiosity-driven inquiry, the scientific pipeline will run dry.
In daily life, people may not feel the effects right away, or even in 10 years. But we will feel it. And when someone we love needs therapies that could have emerged but didn't or when other countries now
investing in science can launch new science-based industries or run their societies on vast resources of fusion energy or reap the benefits of quantum computing power or advanced medical breakthroughs, America will wish it sustained its leadership in scientific research here and now.
Sally Kornbluth is the president of MIT.
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Didier Mazel @amazeld.bsky.social · 28/05/2026
A great opportunity! www.linkedin.com/pulse/join-u...
linkedin.com
Join us in Paris: Systems and Synthetic Biology x AI and health - Inserm Tenuring Position and Starting Package
I'm delighted to announce that we - ELiS Lab / Inserm U1338 at the nascent Paris Biofoundry and the Computational, Quantitative, Synthetic Biology Dept. at the Sorbonne Université - are recruiting an ...
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phoeberice.bsky.social @phoeberice.bsky.social · 26/05/2026
And it is coming from people who rail against "regulations" when up for election. Malicious, wasteful micromanagement.
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Rémi Fronzes @fronzeslab.bsky.social · 26/05/2026
New preprint. In S. sanguinis, a C5a peptidase-like protease (ScpH) polymerizes along eDNA, turning it into a catalytic biofilm scaffold. Great work from @robinanger.bsky.social in our lab, with Pelicic lab @lcbofficiel.bsky.social www.biorxiv.org/content/10.6...
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phoeberice.bsky.social @phoeberice.bsky.social · 26/05/2026
Doesn't it depend on whether RNA or protein levels were measured?
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Cassandra Hayne @cassandrahayne.bsky.social · 25/05/2026
🚨The lab's first research paper is In Press at JBC! Congrats Liza and Magda!! Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization - Journal of Biological Chemistry www.jbc.org/article/S002...
jbc.org
Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization
The Target of EGR1 (TOE1) gene encodes the TOE1 deadenylase, which is essential for the maturation of Pol-II transcribed snRNAs in humans. Over a dozen missense mutations in the TOE1 gene have been li...
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Karolin Luger @nucleosomepolice.bsky.social · 18/05/2026
Out today - structure of the human HIRA histone chaperone complex bound to nucleosomes. Ever wondered how nucleosomes are assembled in the wake of transcription? It takes a 'hulk of a protein complex'. Work by the amazing Wei Tian weetian558.bsky.social. www.biorxiv.org/content/10.6... 🧵
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ARC Tracker @arc-tracker.bsky.social · 08/05/2026
This isn’t the ARC, but I can easily imagine it happening to an ARC scheme: The Government cancelled the Australia’s Economic Accelerator scheme, **including the round of submitted proposals currently under review**. Absolutely gutting for researchers involved. Enraging, and outrageous!
innovationaus.com
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phoeberice.bsky.social @phoeberice.bsky.social · 05/05/2026
Dear Hive Mind, If we wanted to insert a 50-60 bp DNA sequence into a safe spot (or perhaps several different safe spots) in the E. coli chromosome, what would be the simplest / most straightfoward approach these days? Not a big problem if we need a marker that stays there too. Thanks!
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