Reposted by Pablo Ivan NikelInternational Microbiology Literacy Initiative - IMiLI @imili-micro.bsky.social · 06/09/2026¿Por qué la cuajada, el kimchi y la kombucha interesan a los científicos? ¡Porque tu intestino alberga TRILLONES de microorganismos! Los probióticos aportan microorganismos beneficiosos. Los prebióticos los alimentan. Los simbióticos hacen ambas cosas. grupos.eez.csic.es/imili/wp-con... 013
Reposted by Pablo Ivan NikelWeizmann Institute of Science @weizmann.ac.il · 31/08/2026We, the Weizmann Institute of Science community, deeply mourn the passing of Prof. Ada Yonath - Nobel Laureate and a Model of Scientific Perseverance. May her memory be a blessing. bit.ly/ada-yonath-eng 110645
Reposted by Pablo Ivan NikelTom Ellis @proftomellis.bsky.social · 31/07/2026Our lab’s latest on synthetic genomics “Synthetic Combinatorial Minimisation of Cell Cycle Control” is up now on BioRxiv - covering ambitious yeast #synbio cell cycle work led by Anastasiya Malyshava and co-supervised by Matteo Barberis. 1119
Reposted by Pablo Ivan NikelCarboNcare @carboncare-project.eu · 28/07/2026Hello! We are a new @scienceinnovation.ec.europa.eu project building bacteria that only grow by making methanol-based chemicals instead of releasing CO2. 🌬️🦠 📈 Follow our journey and learn more at carboncare-project.eu Eight partners, six countries, one goal: Fermentation 2.0. #microsky 🧪 275
Reposted by Pablo Ivan NikelLars Dietrich @laahrs.bsky.social · 28/06/2026Phenazine Pride #PrideMonth #bacterial_pigments Agar art by Marina Smiley 0359
Pablo Ivan Nikel @pabnik.bsky.social · 23/06/2026PntAB & SthA of #Pseudomonas are a flexible transhydrogenase system, supporting energy balance, acetate assimilation & formate tolerance, impacting redox-intensive & C1 metabolic engineering @michelepartipilo.bsky.social @labnikel.bsky.social @cp-cellsystems.bsky.social www.cell.com/cell-systems...cell.com 0105
Pablo Ivan Nikel @pabnik.bsky.social · 11/06/2026Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida by Javier Hernández @labnikel.bsky.social #SyntheticBiology #MetabolicEngineering #GeneticCircuit #OpenAccess academic.oup.com/nar/article/... @narjournal.bsky.socialacademic.oup.comCascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putidaAbstract. Genetic circuits for model bacteria often perform poorly in non-canonical hosts, limiting the deployment of regulatory programs in industrially r 1158
Reposted by Pablo Ivan NikelSeán Ferrick @seanferrick.bsky.social · 01/06/2026Happy Pride Month! LGBTQIA+ lives are increasingly at risk in 2026, but you'll probably see the usual 'things are better/acceptance has increased/stop shoving it in our faces' No. Love loud, continue to fight, support queer art and businesses, and stand up for your trans siblings :)static.klipy.comElmo's Rainbow Pride CelebrationALT: Elmo's Rainbow Pride Celebration 1018931
Pablo Ivan Nikel @pabnik.bsky.social · 30/03/2026#Pseudomonas vancouverensis as a platform for one-carbon (#C1) assimilation and #polyhydroxyalkanoate accumulation, led by Emil C. Ørsted @labnikel.bsky.social #Biotechnology #MetabolicEngineering #SynBio www.sciencedirect.com/science/arti...sciencedirect.comPseudomonas vancouverensis as a platform for one-carbon (C1) assimilation and polyhydroxyalkanoate accumulationMetabolic engineering calls for new bacterial chassis that combine robust metabolic and physiological traits with genetic tractability. We developed P… 092
Reposted by Pablo Ivan NikelNatural Product Reports @natprodreports.rsc.org · 13/03/2026🔓Check out the #OpenAccess review by @pabnik.bsky.social & co. @labnikel.bsky.social in our latest issue exploring emergent strategies and methods for isolating, creating & characterizing enzymes optimized for bioproduction #natprod Read in full on our website🔽pubs.rsc.orgAccelerating enzyme discovery and engineering with high-throughput screeningCovering: up to August 2024 Enzymes play an essential role in synthesizing value-added chemicals with high specificity and selectivity. Since enzymes utilize substrates derived from renewable… 056
Reposted by Pablo Ivan NikelAmelia Rotaru @ameliarotaru.bsky.social · 12/03/2026💫 I am recruiting a postdoctoral candidate for a 3-year position starting in summer 2026 to work on the role of extracellular RNA (eRNA) in interspecies interactions. 1410
Pablo Ivan Nikel @pabnik.bsky.social · 26/02/2026Very sad news about the passing of Prof. Jeff Cole. Jeff was a central figure for biotechnology in Europe who inspired generations of researchers. R.I.P.🕊️ 061
Reposted by Pablo Ivan NikelMicrobial Biotechnology (MBT) @microbiotech.bsky.social · 29/01/2026#MicroSky: Plasmid vectors still underpin molecular biology, but convenience shouldn’t trump design. De Lorenzo & Martínez revisit copy number, selection & stability, and explores modular AI-assisted vector design for robust synthetic biology across the microbial world. doi.org/10.1111/1751... 0166
Reposted by Pablo Ivan NikelVictor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 27/01/2026How do you react when your favorite microbe is renamed by taxonomists who are completely outside your field—and who ignore the community that actually works with it? Here is our clear answer re the case of Pseudomonas putida KT2440 👉🏻 journals.asm.org/doi/10.1128/...journals.asm.orgThe disputed identity of Pseudomonas putida KT2440: when taxonomists rename your favorite microbe | mBioNames matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad... 23314
Pablo Ivan Nikel @pabnik.bsky.social · 27/01/2026Should an iconic #bacterial #chassis be renamed without community consensus? Our @mbio.bsky.social #article vindicates the established identity of #Pseudomonas putida KT2440 & argues for continuity, community practice & common sense in naming · @vdlorenzo.bsky.social journals.asm.org/doi/10.1128/...journals.asm.orgThe disputed identity of Pseudomonas putida KT2440: when taxonomists rename your favorite microbe | mBioNames matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad... 1176
Reposted by Pablo Ivan NikelKen Timmis @kentimmis.bsky.social · 16/12/2025this is also a contribution to the Scientists' Warning to Humanity series @scientistswarning.bsky.social 001
Reposted by Pablo Ivan NikelKen Timmis @kentimmis.bsky.social · 16/12/2025Happy to post our latest paper: doi.org/10.1111/1751... Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are... 1129
Reposted by Pablo Ivan NikelKen Timmis @kentimmis.bsky.social · 07/12/2025Microbes determine the health of all other organisms and that of the planet. They were our ancestors and are our cousins. They are life and sustain it. Microbes are life, the biological core of One Health and Health in All Policies url: academic.oup.com/microlife/ar...academic.oup.comMicrobes are life, the biological core of One Health and Health in All PoliciesThe World Health Organization (WHO) is promoting the operative concept of “Health in All Policies” (HiAP; https://iris.who.int/bitstream/handle/10665/11263 022
Reposted by Pablo Ivan Nikel🌈 Dr Ross Brooks @rossbrooks.co.uk · 07/11/2025So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️⚧️🔭🏳️🌈🚆 Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏 lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️lgbtplushistorymonth.co.ukLGBT+ History Month 2026 - LGBT+ History MonthIf you’d like to donate to support our work, click here to donate via PayPal. Free Schools Presentation For 2026 we are able to offer free LGBT+ History Month presentations for secondary schools, prid... 24112
Pablo Ivan Nikel @pabnik.bsky.social · 03/11/2025Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑 www.nature.com/articles/s41... 23315
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 22/08/2025🚨 New paper in mBio! We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10.... Here’s a teaser of how we did it 🧵👇1/5journals.asm.orgSynthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway | mBioSoluble C1 feedstocks, such as formate and methanol, have gained attention as sustainable substrates for biotechnology, with the potential to reduce greenhouse gas emissions and reliance on sugar-based resources. Despite their promise, the metabolic ... 21710
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 08/10/20253/4 Our perspective lays out: 1️⃣ A blueprint for designing next-gen synthetic C1 microbes 2️⃣ A roadmap for engineering P. putida into an autotrophic chassis 3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams 📊 Together, these steps connect design → engineering → sustainability. 111
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 08/10/2025🚀 Thrilled to share our new Nature Communications article: “A blueprint for designing the next-generation of synthetic C1 microbes” We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts. 🔗 www.nature.com/articles/s41... A short 🧵1/4nature.comA blueprint for designing the next-generation of synthetic C1 microbes - Nature CommunicationsSynthetic one-carbon assimilation could contribute to a more sustainable and circular carbon economy, but much work in this field has focused on model microorganisms. Here the authors provide their perspective on the potential value of non-model microbes, and how that potential could be realised. 187
Pablo Ivan Nikel @pabnik.bsky.social · 03/10/2025A blueprint for designing the next-generation of #synthetic C1 #microbes @natureportfolio.nature.com / We outline how to engineer non-canonical hosts, apply modeling & C1-inducible promoters & integrate sustainability metrics for carbon-efficient #biomanufacturing www.nature.com/articles/s41...nature.comA blueprint for designing the next-generation of synthetic C1 microbes - Nature CommunicationsSynthetic one-carbon assimilation could contribute to a more sustainable and circular carbon economy, but much work in this field has focused on model microorganisms. Here the authors provide their perspective on the potential value of non-model microbes, and how that potential could be realised. 063
Pablo Ivan Nikel @pabnik.bsky.social · 24/09/2025The very 1st #Course on #SynBio & #Metabolic #Engineering of #Pseudomonas at Cold Spring Harbor Asia successfully completed in Suzhou, #China! Excellent group of students & lecturers, w/time for culture, food & stand-up paddling alongside the science—thanks to all who participated & stay tuned 4+! 0102
Reposted by Pablo Ivan NikelInternational Microbiology Literacy Initiative - IMiLI @imili-micro.bsky.social · 23/09/2025Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org 11815
Reposted by Pablo Ivan NikelVictor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 24/09/2025Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.socialbiorxiv.orgSynthetic Horizontal Gene Transfer for Ecosystem RestorationRestoring endangered ecosystems has become a pressing issue as the effects of global warming continue to harm existing communities. Over the last decade, several studies have suggested the use of synt... 193
Reposted by Pablo Ivan NikelAndreas P.M. Weber 🌾🌱🧬 @apmweber.bsky.social · 03/09/2025We are deeply saddened by the news that Andrew D. Hanson (@adhansonlab.bsky.social) is no longer with us. He was an exceptional scientist, mentor, and leader in multiple fields. He constantly reminded us that over-promising would backfire. Rest in peace, Andrew. 32317
Pablo Ivan Nikel @pabnik.bsky.social · 02/09/2025Delighted to join #MetabolicEngineering as Associate Editor w/Sang Yup Lee, Jay Keasling, I. Borodina, C. Maranas & C. Wittmann. I'll handle submissions in #SyntheticMetabolism, #Pseudomonas, #SynBio, new-to-nature #bioproduction & #EnvironmentalBiotechnology! 080
Pablo Ivan Nikel @pabnik.bsky.social · 21/08/2025Saying goodbye to Elio Schaechter, a titan of the #Microbiology field. Farewell Elio! 241
Pablo Ivan Nikel @pabnik.bsky.social · 21/08/2025#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio journals.asm.org/doi/10.1128/...journals.asm.orgSynthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway | mBioSoluble C1 feedstocks, such as formate and methanol, have gained attention as sustainable substrates for biotechnology, with the potential to reduce greenhouse gas emissions and reliance on sugar-based resources. Despite their promise, the metabolic ... 0125
Reposted by Pablo Ivan NikelSEVA Plasmids @sevaplasmids.bsky.social · 16/07/2025🔍Problems with synthetic C1 metabolism? The @pabnik.bsky.social group identifies seven major barriers limiting its deployment in microorganisms and proposes specific strategies to overcome each of them. Check out their paper 👉https://doi.org/10.1093/femsre/fuaf011 043
Reposted by Pablo Ivan NikelTOLERATE EU Project @tolerateeu.bsky.social · 15/07/2025📍 Milan | TODAY! Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges 🕦 15 July | 11:30–13:00 | Tower Lounge 🔗 femsmicro.org ▶️ youtu.be/0-bhcMpjJ_c #TolerateEUProject 142
Pablo Ivan Nikel @pabnik.bsky.social · 13/07/2025Looking forward to see old MicroFriends and make some new ones at #FEMS2025! 070
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 09/07/2025Check out our newest article led by @oscarpuiggene.bsky.social ! 051
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 09/07/2025The 5th edition of the #Pseudomonas grass roots meeting will take place on the 27th/28th of October 2025 in Denmark. This year, our group at DTU Biosustain will host 2 exciting days of networking, exchanging ideas and learning for early career-stage scientists working with Pseudomonas. 👇 122
Reposted by Pablo Ivan NikelSEVA Plasmids @sevaplasmids.bsky.social · 09/07/2025🧬 The language of SEVA expands! The group of @pabnik.bsky.social use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria. 👉 doi.org/10.1016/j.ym...doi.orgRedirecting 001
Pablo Ivan Nikel @pabnik.bsky.social · 09/07/2025🚨 Due to popular demand, the deadline to apply for the @cshlnews.bsky.social course Advanced #SynBio & #Metabolic #Engineering of #Pseudomonas is extended to July 22! #PhD students & #postdocs welcome! 📍Suzhou, China 📅 Sept 7–21 🔗Apply now: csh-asia.org?content/2642 010
Pablo Ivan Nikel @pabnik.bsky.social · 07/07/2025Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social www.sciencedirect.com/science/arti...sciencedirect.comSystematic engineering of synthetic serine cycles in Pseudomonas putida uncovers emergent topologies for methanol assimilationThe urgent need for a circular carbon economy has driven research into sustainable substrates, including one-carbon (C1) compounds. The non-pathogenic… 072
Reposted by Pablo Ivan NikelTOLERATE EU Project @tolerateeu.bsky.social · 30/06/2025Today, the #TOLERATEProject held its 1st Review Meeting (M1–M18) with PO & PM highlighting our progress, innovation & first results. A key step to shape the road ahead! 🔬🌱💦 Learn more: tolerate-eu-project.com #HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture 022
Reposted by Pablo Ivan NikelTOLERATE EU Project @tolerateeu.bsky.social · 01/07/2025🌱⚖️ Is EU law keeping up with agri-food innovation? Our latest TOLERATE article explores how outdated GMO/NGT rules could hinder progress. Thanks to Mirta Alessandrini & Francesco Montanari for their legal insights. 👉 Read more: tolerate-eu-project.com/tolerate-agr...tolerate-eu-project.comTOLERATE - Agri-food Science & Law Join Forces Against Climate ChangeResurrecting Ancient Genes with Synthetic Biology to Tackle Modern Challenges - Cyprus Institute of Neurology & GeneticsSetting the scene Agriculture has been the most important source of sustenance for mankind for thousands of years. However, current farming practices are often singled out as key drivers of climate ch... 001
Reposted by Pablo Ivan Nikellabnikel.bsky.social @labnikel.bsky.social · 23/06/2025Back from an inspiring week at #ME16 in our home #Copenhagen! 🌍 Engaging talks, exciting science, and amazing connections — we’re full of new ideas! 🎉 Big congrats to @giusifav.bsky.social for winning a poster award 🏆 🙌 And proud to have our PI @pabnik.bsky.social as co-chair of the event! 142
Pablo Ivan Nikel @pabnik.bsky.social · 22/06/2025Wrapping up a fantastic #ME16 #Copenhagen — a success by all measures! Honored to co-chair the meeting w/I. Borodina, M. Chang, A. Mirończuk, C. Vickers, V. Šťovíček, Y. Zhou, M. Köpke & M. Herrgård & to work w/an outstanding team of colleagues, engaging communities & topics all around the world 0121
Pablo Ivan Nikel @pabnik.bsky.social · 09/06/2025Happy to host @kunjapur.bsky.social as a sabbatical #professor at DTU Biosustain, supported by Otto Mønsteds Fond! We share a passion for using #SynBio to engineer #microbes with non-natural building blocks for advanced #biotechology. He’s in #Europe — drop a line to connect & discuss cool #Science! 1151
Reposted by Pablo Ivan NikelPatricia Bernal @pbernalt6ss.eurosky.social · 12/05/2025Great science @pabnik.bsky.social and collaborators!! 072
Reposted by Pablo Ivan NikelAndrew D Hanson @adhansonlab.bsky.social · 16/04/2025#SyntheticBiology postdoctoral position in our group in University of Florida's Horticultural Sciences department. Work is directed evolution to improve enzymes that underlie important crop traits ⬇️ 054
Reposted by Pablo Ivan NikelSheila I. Jensen @sheilaijensen.bsky.social · 08/04/20251/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles. www.nature.com/articles/s41...nature.comHigh-efficiency water use and process performance for bioproduction of trans-cinnamic acid - Scientific ReportsScientific Reports - High-efficiency water use and process performance for bioproduction of trans-cinnamic acid 183
Reposted by Pablo Ivan NikelCecilia G. Flocco @ceciliaflocco.bsky.social · 04/04/2025The #SynMicro Group was est. just last year, with Markus Pötter & myself elected as its first speakers. We were fortunate to welcome @pabnik.bsky.social as our invited speaker, alongside outstanding short lectures from Anna C. Ngo, Tim Stoltmann, Laura da Silva Amorim and Daniel Stukenberg. 2/n 151
Pablo Ivan Nikel @pabnik.bsky.social · 02/04/2025Genetic dissection of cyclic di-GMP signalling in #Pseudomonas aeruginosa via systematic diguanylate cyclase disruption—led by Roman di Martino & Daniel Volke @labnikel.bsky.social @microbiotech.bsky.social #OpenAccess enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....enviromicro-journals.onlinelibrary.wiley.comGenetic Dissection of Cyclic di‐GMP Signalling in Pseudomonas aeruginosa via Systematic Diguanylate Cyclase DisruptionAll 32 diguanylate cyclase (DGC)-encoding genes of P. aeruginosa PA14 were interrupted by premature STOP codons, introduced through a multiplexed cytosine base-editor. The synthesis of c-di-GMP was i... 0104
Reposted by Pablo Ivan NikelCecilia G. Flocco @ceciliaflocco.bsky.social · 24/03/20252/n If you are at #vaam2025, come join us for the Inaugural Symposium of the brand new #Synthetic #Microbiology Group, featuring @pabnik.bsky.social Center for Biosustainability DTU and a line up of rising stars ✨ #microsky @leibniz-dsmz.bsky.social programme.conventus.de/vaam-2025/pr... 042