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Cassandra Hayne

@cassandrahayne.bsky.social
2.5K followers 963 following 106 posts

RNA Biochemist, leads the Hayne Lab at UChicago. haynelab.com Views are my own (she/her)

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Cassandra Hayne @cassandrahayne.bsky.social · 19/09/2026
In a world where we ’could’ just hop on zoom or read a paper online, how cool is it that hundreds of people with shared scientific interests fly across the world to get together and share their latest published and unpublished data to move the field forward. Excited for #tRNA2026!
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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 11/09/2026
ASBMB is excited to announce the Future of Discovery Program and ASBMB Impact Fund, two new initiatives that will expand travel award support for graduate students and postdoctoral fellows attending the ASBMB Annual Meeting. Learn more & apply: www.asbmb.org/asbmb-today/... #ASBMB2027
Promotional graphic for the ASBMB Annual Meeting 2027 in Boston, April 3–6. White text on a blue and teal background with a DNA helix illustration reads: “ASBMB expands graduate student and postdoc travel awards.” ASBMB Annual Meeting ’27 branding appears at the top with “Molecular Bioscience.”
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Drummond Lab @drummondlab.bsky.social · 08/09/2026
We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Join us! apply.interfolio.com/191981 bcmb.uchicago.edu
A picture of the University of Chicago campus, with downtown Chicago in the distance and Lake Michigan on the horizon. The campus's central quad is pictured, a classical collegiate quad with paths and old trees and stone architecture. It's really pretty and I love it.
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Cassandra Hayne @cassandrahayne.bsky.social · 02/09/2026
The Department of Biochemistry and Molecular Biology at #UChicago is looking for a new junior faculty member to join us. If you or someone you know would be a good fit, please apply or encourage them to apply! apply.interfolio.com/191981
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Lauren Palmer @laurenpalmer.bsky.social · 28/08/2026
Our new paper shows AstR is required to activate ornithine catabolism for A. baumannii to compete with the microbiota in the gut reservoir Led by fantastic first authors John Geary and Xiaomei Ren! 🥳
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Cassandra Hayne @cassandrahayne.bsky.social · 25/05/2026
Looking forward to sharing this story in person at #RNASociety on Friday! I'm giving a talk at the RNA and Disease session and Liza will have a poster (ID 528) on Friday evening.
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Cassandra Hayne @cassandrahayne.bsky.social · 25/05/2026
🚨The lab's first research paper is In Press at JBC! Congrats Liza and Magda!! Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization - Journal of Biological Chemistry www.jbc.org/article/S002...
jbc.org
Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization
The Target of EGR1 (TOE1) gene encodes the TOE1 deadenylase, which is essential for the maturation of Pol-II transcribed snRNAs in humans. Over a dozen missense mutations in the TOE1 gene have been li...
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John Peters @peterslab-ur.bsky.social · 02/04/2026
1/8 I am excited to share a new paper from the education side of the lab. There is a lot of anxiety that genAI tools will jeopardize learning gains from homework assignments. Using Bloom's Taxonomy, we analyzed where genAI succeeds and where it struggles. journals.plos.org/plosone/arti...
journals.plos.org
Designing life science assessments in the era of generative artificial intelligence
Generative artificial intelligence (GAI) algorithms have the potential to reshape education. Though GAI may help democratize access to education, it also presents many challenges for educators. Alread...
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Junior RNA scientists @jrrnascientists.bsky.social · 27/03/2026
Heads up all Junior RNA Scientists - March 31st is the deadline for poster abstract submission and early bird registration for the 2026 Annual RNA Society Meeting in Montreal! Don't miss out, we have an exciting panel and fun events planned!
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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 24/03/2026
As a child, @phosphotig.bsky.social dreamed of being an astronaut, but her curiosity led her to scientific research. Now, she leads her own lab at UNC-Chapel Hill, & studies oxidative stress to find better therapies for triple-negative breast cancer. #WomensHistoryMonth www.asbmb.org/asbmb-today/...
asbmb.org
Learning, leading and lifting others
Tigist Tamir’s journey from aspiring astronaut in Ethiopia to cancer researcher at the University of North Carolina highlights the power of mentorship, persistence and curiosity in shaping a scientifi...
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I-75 Scientist @flscitriguy.bsky.social · 19/03/2026
NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...
grants.nih.gov
NOT-GM-26-002: Notice of NIGMS Participation in PA-25-422 "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)"
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of NIGMS Participation in PA-25-422
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Abby Buchwalter @abbybuch.bsky.social · 19/03/2026
A piece of good news for basic scientists in training!
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Cassandra Hayne @cassandrahayne.bsky.social · 17/03/2026
Got my first conference attendee scam. Assume they targeted names on the website for: #RNASociety See lots more of this lately.
Hello Dr. 

We are pleased to confirm your participation in Montreal, QC, Canada  – May 2026.


Kindly share your intended check-in and check-out dates so that we can proceed with reserving your accommodation at our partner hotel.

Please note that our reservations are flexible, and any modifications can be made up to 14 days before your arrival date. For more details about our reservation policies, please visit the link below.

We look forward to your confirmation at your earliest convenience.

Best regards,
Reservations Team


Our Team Available for any assistance or inquires 24/7.
Our contact information :
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Cassandra Hayne @cassandrahayne.bsky.social · 06/03/2026
I was on Capitol Hill today with @asbmb.bsky.social urging lawmakers to support strong federal investment in scientific research and training. Also to support : predictable and sustained funding. #ASBMBAdvocates #ScienceServesUsAll
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Anita Corbett @acorbe2.bsky.social · 06/03/2026
Folks from @rnasociety.bsky.social advocating for basic science research funding #ASBMBAdvocates @uwmadisonrna.bsky.social @cassandrahayne.bsky.social
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Jeremy Berg @jeremymberg.bsky.social · 05/03/2026
New and competitive renewal awards Fewer than 40 new awards were made in the past week, compared to over 100 the previous week. 5/9
A line graph showing the number of NIH new and competitive renewal awards funded in fiscal year 2026 compared to fiscal years 2020-2025. The fiscal year 2026 curve lies below the other curves and appears to be flattening out somewhat. A total of 840 awards have been made in fiscal year 2026.
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Jeremy Berg @jeremymberg.bsky.social · 05/03/2026
This flattening may be due to the apportionment issue covered in the recent Nature story. www.nature.com/articles/d41... 3/9
nature.com
White House stalls release of approved US science budgets
The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.
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Jeremy Berg @jeremymberg.bsky.social · 05/03/2026
All projects The fiscal year 2026 appears to be flattening out a bit in the past week. 2/9
A line graph showing the number of NIH projects funded in fiscal year 2026 compared to fiscal years 2020-2025. The fiscal year 2026 curve lies below the other curves and appears to be flattening out somewhat.
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Rebecca Berlow @berlowlab.bsky.social · 24/01/2026
New preprint alert! We share some of our recent insights about sequence similarity in IDP protein families and find that conservative substitutions in well-conserved binding motifs of the CITED proteins have big impacts on their ensembles and functions. Take a look! www.biorxiv.org/content/10.6...
biorxiv.org
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eLife @elife.bsky.social · 28/12/2025
A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV
The commitments in the SAFE Labs Handbook.
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Chrystal Starbird @drstarbird.bsky.social · 08/12/2025
www.statnews.com/2025/12/08/t...
statnews.com
NIH shut out hundreds of young scientists from funding to start their own labs
Special Report: The NIH has shut out hundreds of young scientists from funding to start their own labs.
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Ariane Briegel @arianebriegel.bsky.social · 18/11/2025
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
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Erin Green @erinrgreen.bsky.social · 04/10/2025
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
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Molly Schumer @mollyschumer.bsky.social · 29/09/2025
What are people using for calling m6A from pacbio revio data? This is for analysis of fiberseq library. Any suggestions appreciated, we are newbies with m6A analysis!
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MagnoliaBouton @magnoliabouton.bsky.social · 25/08/2025
Listed are some of the many NIH research training programs that were terminated! Together, these programs supported thousands of trainees, whose careers are now in limbo. Such a great loss for discovery and innovation. We must protect our next generation of scientists! #HandsOffNIH #ProtectScience
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Harmit Singh Malik @harmitmalik.bsky.social · 23/08/2025
It bears repeating that nearly the entire US enterprise in science and technology has been irreversibly gutted. This is shocking. All this loss has occurred without any real benefit to the average US citizen. Except we now have the biggest, best funded secret police force perhaps ever. Yay for us!
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Cassandra Hayne @cassandrahayne.bsky.social · 23/08/2025
I’ve had a lab for less than 3yrs. In that time the costs of many science reagents have grown faster than inflation. I ordered an antibody today that I paid $383 for in 2023- today with a good promotion, I paid $467. Tariffs on top of that. Other easy examples: Grids are up about 30% Gloves up 25%
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27 UNIHTED @27unihted.bsky.social · 22/08/2025
A joint statement with @savehealthresearch.bsky.social on the supreme courts decision today that will pave the way for hundreds of millions of dollars in NIH grant terminations. We are heartbroken and stand with the extramural community during this devastating time.
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Gregg Gonsalves @gregggonsalves.bsky.social · 21/08/2025
There is no solace for NIH funded researchers in this Supreme Court decision. Grants that were ripped away on dubious grounds, restored by a reasonable judge are now again terminated by an out-of-control Supreme Court. Labs will shutter, people will lose jobs. www.reuters.com/world/us/us-...
reuters.com
US Supreme Court lets Trump cut diversity-related NIH grants
The U.S. Supreme Court let President Donald Trump's administration on Thursday proceed with sweeping cuts to National Institutes of Health grants for research related to racial minorities or LGBT people, part of his crackdown on diversity, equity and inclusion initiatives and transgender identity.
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Journal of Cell Science @jcellsci.bsky.social · 15/08/2025
Why would anyone want to be a scientist? Check out our new Essay from Martin Schwartz: journals.biologists.com/jcs/article/...
Screenshot of Essay from Martin Schwartz on 'Why would anyone want to be a scientist'. An anniversary article from The Company of Biologists published in Journal of Cell Science.

The first few lines are: It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection. But, strange even to myself, I not only don't question the unfavorable risk-to-reward ratio but consider myself astonishingly lucky to be a scientist. There are three fundamental pleasures that have sustained me through 50 years of this madness.
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TanentzapfLab @tanentzapflab.bsky.social · 08/08/2025
I think a good rule of thumb is to spend at least as much time thinking about your data as you did obtaining it. It's common for people to spend a lot less time thinking than doing which gives rise to all kinds of problems.
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Jeremy Berg @jeremymberg.bsky.social · 08/08/2025
New Notice about No-Cost Extensions... grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-142: Update: No-Cost Extension Functionality in eRA
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Update: No-Cost Extension Functionality in eRA NOT-OD-25-142. NIH
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Ryan Marino, MD @ryanmarino.bsky.social · 15/07/2025
There’s a nonzero chance you will die from a cancer that could have been curable because people who couldn’t pass 7th grade biology and are scared of things like “mRNA” and “riboflavin” and “walkable cities” decided to make their ignorance everybody else’s problem
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Denis Wirtz @deniswirtz.bsky.social · 14/07/2025
Grant terminations have grabbed the headlines and have seen legal action, but even more damaging to the US research enterprise has been the massive decrease in number of research grants issued by federal agencies NIH has seen a decrease of 57% in the number of awards & 63% in value compared to FY24
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 25/06/2025
A big thanks to NC Sen. Thom Tillis for being the first signature on this bipartisan letter urging the Senate to maintain a strong commitment to funding for NIH in the Labor, Health and Human Services, and Education FY 2026 Appropriations bill. Is your Senator here? www.aamc.org/research/adh...
text in the link
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Karolin Luger @nucleosomepolice.bsky.social · 03/06/2025
Please share widely with friends, family, and foes. You can read it for free without a subscription. www.nytimes.com/2025/06/03/u...
nytimes.com
U.S. Scientists Warn That Trump’s Cuts Will Set Off a Brain Drain
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Don Moynihan @donmoyn.bsky.social · 27/05/2025
*International students represent about 15% of all higher ed students. *They subsidize US students, so expect domestic student costs to increase *Trump complains about tariffs but he is destroying an industry where the US is a huge net exporter www.nytimes.com/2025/05/23/u...
Higher education is, effectively, a major American export — and one where the foreign students consuming it do so in American communities, also spending money on housing, groceries and books there. More than 1.1 million international students contributed about $43 billion to the U.S. economy during the 2023-24 academic year, most of it on tuition and housing, according to an analysis by NAFSA, a nonprofit association of international educators.
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Cassandra Hayne @cassandrahayne.bsky.social · 27/05/2025
Excited to be headed to San Diego for my first *in person* RNA Society meeting. ☀️ Looking forward to great science and time with great scientists. See you there #RNASociety #RNASky
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Max Kozlov @maxkozlov.bsky.social · 21/05/2025
Who's calling the shots at NIH? Sworn testimonies and internal e-mails reveal for the first time the breadth of DOGE's control over the world's largest public biomedical funder. DOGE has provided lists of hundreds of grants to cut, and DOGE is now reviewing ALL NIH awards before they're released
nature.com
NIH killed grants on orders from Elon Musk’s DOGE
Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.
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Jeremy Berg @jeremymberg.bsky.social · 20/05/2025
New Forbes story about the economic consequences of science cuts. www.forbes.com/sites/johndr... Thoughtful and thorough analysis. 1/n
forbes.com
Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually
Economists find public R&D drives U.S. productivity growth — and pays for itself
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Cassandra Hayne @cassandrahayne.bsky.social · 21/05/2025
Congrats Max, Stephanie et al!
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Anita Devineni @anitadevineni.bsky.social · 21/05/2025
ICYMI: The FDA wants to restrict access to Covid vaccines, even though they are safe, effective, and have saved millions of lives. Even ppl in high-risk jobs wouldn't get access. We can push back by submitting public comments here: www.regulations.gov/commenton/FD... www.nytimes.com/2025/05/20/h...
nytimes.com
F.D.A. Poised to Restrict Access to Covid Vaccines
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Kara McKinley @karalmckinley.bsky.social · 16/05/2025
Thinking of this post today
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Stand Up for Science! @standupforscience.net · 10/05/2025
HAPPY 75th, NSF! We’re celebrating this milestone by highlighting some of NSF’s most transformative accomplishments—innovations that have shaped our world and continue to drive progress in health, technology, the environment, and beyond. Read on 🧵(1/11):
A chocolate cake with red and white decorations and lit candles shaped as the number 75. Bold text reads: ‘The NSF Turns 75 Today. What has it done over the past 7 decades?’ The background is a celebratory red with a spray-paint texture.
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The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 05/05/2025
I updated the Resources page of my blog, and made it easier to find, so that you can more easily find go-to content....
thebumblingbiochemist.com
Resources
Skip to: Some key links • Key blog pages & uploads • Posts & videos by date & topic • Key database and software links • Techniques I use a lot • Downloadable guides • Laboratory cheat sheets • Other l...
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Colm Atkins, PhD @atkinscolm.bsky.social · 02/05/2025
Welp, it begins. Sigma Aldrich.
To maintain our operational integrity and continue delivering the service and quality our customers rely on, we have made the decision to implement a tariff surcharge. This temporary surcharge is in lieu of a tariff cost passthrough and protects our customers from experiencing the full impact of the broad tariff rates, some of which are very high. By leveraging a surcharge, we retain flexibility to adjust or remove the surcharge if the situation changes in the coming weeks or months.

Effective May 5, the surcharge will be applied to product orders shipped to locations in the United States which reflects the tariffs' broader impacts on our overall global supply chain processes, including production and procurement costs in addition to any direct costs on products. This charge will appear as a separate line item on quotes and invoices.
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Katie Mack @astrokatie.com · 30/04/2025
I could be wrong about this but I really think most Americans do not want to be forced to “do their own research” about food & drug & product safety and would rather that the government agencies that have been sorting that all out for them for decades not be obliterated in the name of “efficiency.”
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Maya Emmons-Bell @maya-emmonsbell.bsky.social · 30/04/2025
At first glance, it looks like most terminated grants from the NIH are R01s, which are awarded to established scientists to fund the work of their labs. The next most common grant category is the F31, a training grant supporting the professional development of outstanding graduate students.
bar plot showing the distribution of cancelled grants across NIH activity codes.
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Jeremy Berg @jeremymberg.bsky.social · 01/05/2025
Science article with perspectives from NIH insiders www.science.org/content/arti... 1/n
science.org
NIH insiders: Trump is ‘dismantling and destroying everything’
After just 100 days, agency scientists say U.S. health institutes are demoralized and have lost essential staff and funding
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