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Kevin Corbett

@kevincorbett.bsky.social
118 followers 10 following 4 posts

UCSD, bacteria, meiosis

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Kevin Corbett @kevincorbett.bsky.social · 04/09/2026
I'm thrilled to share that UCSD Biological Sciences has launched an open-rank search for a transformational researcher, with a particular focus on structural biology/cryoelectron microscopy! Come to UCSD and enjoy our fantastic research community, world-class facilities 🔬, and pretty good weather 🌴🏖️
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Reposted by Kevin Corbett
Hajime Murakami @alhajijoker.bsky.social · 08/07/2026
Happy to share the first preprint from our lab, led by @arrosan.bsky.social, in collaboration with @ccb-lab.bsky.social. We identify a conserved cohesin-interacting motif in Red1 required for its recruitment, DSB formation, and Mek1 activation. www.biorxiv.org/content/10.6... #meiosis #recombination
biorxiv.org
Cohesin–axis interaction via a conserved Red1 motif promotes domain-specific DSB formation and Mek1 activation
Faithful chromosome segregation during meiosis I requires tight control of interhomolog recombination. In budding yeast, the meiotic chromosome axis, built on Rec8-containing cohesin together with Red...
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Kevin Corbett @kevincorbett.bsky.social · 11/04/2026
Congrats to Chase Morgan @phagemorgan.bsky.social and the phage team!
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Kevin Corbett @kevincorbett.bsky.social · 30/12/2025
Congratulations to Doi Basu @dwaipayanbasu.bsky.social for publishing his first first-author paper from the lab! The cryoEM structure of a tubulin-like protein from bacteriophage Goslar forms "microtubules" with nine protofilaments! authors.elsevier.com/a/1mM253SNvc...
authors.elsevier.com
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Reposted by Kevin Corbett
Biswajit Pradhan @bislightyear.bsky.social · 02/12/2024
Happy to see our research on SMC Wadjet published in Molecular Cell. We showed DNA loop extrusion (LE) by a bacterial SMC, confirming LE is conserved across all life forms. Wadjet's LE activity is crucial for recognizing and restricting foreign plasmids, serving as a defense mechanism. 🧬🔬🧪
Graphical abstract showing the loop extrusion mechanism of the Wadjet complex, which selectively cleaves circular DNA while leaving linear DNA unaffected.
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Reposted by Kevin Corbett
bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 22/11/2024
Structural diversity and oligomerization of bacterial ubiquitin-like proteins www.biorxiv.org/content/10.1101/202…
biorxiv.org
Structural diversity and oligomerization of bacterial ubiquitin-like proteins https://www.biorxiv.org/content/10.1101/2024.11.21.623966v1
Bacteria possess a variety of operons with homology to eukaryotic ubiquitination pathways that encod
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Reposted by Kevin Corbett
bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 22/11/2024
Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway www.biorxiv.org/content/10.1101/202…
biorxiv.org
Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway https://www.biorxiv.org/content/10.1101/2024.11.21.623953v1
Ubiquitination is a fundamental and highly conserved protein post-translational modification pathway
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