Complement component 1q (C1q), the initiator of the classical complement cascade, mediates synaptic elimination in development and disease, yet the triggers for its deposition on synapses remain uncle...

UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...

UK Glia 2026, Bristol. Unites researchers across career stages to explore glial biology, brain physiology, neurodegeneration and neuropsychiatric disorders.

UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...

In this review, we discuss the development and maturation of inhibitory neurons and astrocytes and how early developmental activity in the brain might promote the interactions between these cell type...

UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...

The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.

Hyperpolarised 129Xe Nuclear Magnetic Resonance (NMR) Spectroscopic Brain Oximetry

Employing pharmacology, genetics and all-optical approaches in zebrafish, Braaker et al. find that neuronal activity influences the growth of myelin sheaths along axons by signaling through metabotrop...

In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to involve isolation of the central ner...

Hematopoietic stem cell transplant is the gold standard for treatment of globoid cell leukodystrophy, also called Krabbe disease. Aisenberg et al. define the molecular signature of disease-associated ...

Remyelination, the process by which axons are re-encased in myelin after injury, is a critical step in restoring brain function, yet the dynamics from initial injury to repair remain poorly characteri...

The astrocytes that cover the brain and spinal cord and protect it from intruders lack the signature star shape and have a distinct genetic marker.

Research Associate in Multimodal Neuroimaging and Physiological Modelling

The astrocytes that cover the brain and spinal cord and protect it from intruders lack the signature star shape and have a distinct genetic marker.

The astrocytes that cover the brain and spinal cord and protect it from intruders lack the signature star shape and have a distinct genetic marker.

What is the UK Glia network? The UK Glia network has been founded by a group of scientists representing all fields of glia research. Our primary goal is to create a community for glia researchers work...

Glial cells are fundamental for the pathophysiology of all neurological disorders. Astrocytes, the primary homeostatic cells of the central nervous system (CNS), exhibit species-specific characteristi...

Join us at the Keystone Symposia on Neural-Immune Interactions: A Systems-Wide Perspective on Whole Organism Physiology, June 2025, in Whistler, with field leaders!

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Hasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...

Normal aging alters brain functions and phenotypes. However, it is not well understood how astrocytes are impacted by aging, nor how they contribute to neuronal dysfunction and disease risk as organis...