iiinova — where your digital self keeps evolving

Shane Liddelow @liddelowsa.bsky.social · 05/08/2026

Exciting paper alert. Bravo to @borderbiologist.bsky.social and everyone who worked on the paper.

Shane Liddelow @liddelowsa.bsky.social · 10/07/2026

Just a short walk from outside the poster hall to inside the poster hall at #FENS2026 🫠 On the plus side: getting my steps in for extra patatas bravas later 😬

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Shane Liddelow @liddelowsa.bsky.social · 29/06/2026

One to watch, and one to join! New lab alert. Go A Prof Prakash!

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Melissa Cooper, PhD @melcooperphd.bsky.social · 04/05/2026

Interested in finding your own astrocyte networks? The plasmid is now available on Addgene! www.addgene.org/252501/ Check out how we implemented it in this paper, published in Nature: www.nature.com/articles/s41... Need extra guidance? Watch this space for a more detailed protocol paper soon!

nature.com

Astrocytes connect specific brain regions through plastic networks - Nature

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

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Shane Liddelow @liddelowsa.bsky.social · 18/05/2026

Sorry all, some gliaseq datasets went down over the weekend. They should be up and functioning again soon (if not already). Please do reach out if there are additional bugs. MORE data coming soon!

static.klipy.com

David Rose: And For That I Am Apologetic

ALT: David Rose: And For That I Am Apologetic

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Melissa Cooper, PhD @melcooperphd.bsky.social · 22/04/2026

Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!

nature.com

Astrocytes connect specific brain regions through plastic networks - Nature

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

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Charleston Conference on Alzheimer's Disease (CCAD) @the-ccad.bsky.social · 07/04/2026

Congratulations Melissa Cooper, PhD of NYU Langone Health, a 2026 New Vision Research Awardee! Her $100K grant will fund “Astrocyte Networks in Alzheimer’s Disease” exploring how brain cell networks drive disease and reveal new therapies. #CCAD2026 #AlzheimersResearch

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Mariko Bennett @nachoriko.bsky.social · 24/03/2026

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

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Shane Liddelow @liddelowsa.bsky.social · 02/12/2025

Read about one of the fantastic postdocs in the lab - @pryprk.bsky.social. Thanks to The Scientist for running this exciting series! Priya is on the job market atm - so keep your eyes peeled for exciting things to come from her lab soon! :-)

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Shane Liddelow @liddelowsa.bsky.social · 19/11/2025

#SfN #SocietyForGlia #Astrocytes ENDING STRONG in Astrocyte land here in San Diego. Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions. See you in 2026!

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Shane Liddelow @liddelowsa.bsky.social · 19/11/2025

#SfN25 #SocietyForGlia #Astrocytes penultimate astrocyte sessions for 2025 - let's do this!

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Shane Liddelow @liddelowsa.bsky.social · 18/11/2025

#SfN #SocietyForGlia STARTING NOW! Ending strong with the last www.liddelowlab.com presentations of the week. @pryprk.bsky.social talking about a world first mouse model for XDP... and OLIGODENDROCYTES! @melcooperphd.bsky.social presenting on astrocyte networks in the mouse forebrain.

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Shane Liddelow @liddelowsa.bsky.social · 18/11/2025

#SfN25 #SocietyForGlia #Astrocytes IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time! as always, apologies to those I have missed - please comment below with more sessions and presentations!

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Shane Liddelow @liddelowsa.bsky.social · 17/11/2025

IT'S A BUSY AFTERNOON FOR THE LAB! @mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?) @liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity

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NYULH Neuroscience @nyulhneuro.bsky.social · 17/11/2025

It's a packed day for our researchers at #SfN25. Come say hi!

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Shane Liddelow @liddelowsa.bsky.social · 17/11/2025

#SfN25 #SocietyForGlia #Astrocytes Monday is a BUSY day - see you all out there! (apologies for anyone's presentation I missed - please comment below with details)

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Shane Liddelow @liddelowsa.bsky.social · 16/11/2025

#SocietyForGlia #SfN25 #Astrocytes Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see. Apologies again for anyone I missed - please link your presentations below

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Shane Liddelow @liddelowsa.bsky.social · 15/11/2025

#SocietyForGlia #SfN25 #Astrocytes Astrocyte presentation round up for Day 1. Sorry if I missed anyone, please comment below with others! See you about the conference

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Shane Liddelow @liddelowsa.bsky.social · 15/11/2025

#SfN25 #SocietyForGlia #Astrocytes @borderbiologist.bsky.social presenting now! Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!

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Priya Prakash @pryprk.bsky.social · 13/11/2025

Very happy to have contributed to this new review on Lewy body dementia in @thelancetneuro.bsky.social led by Sonja W. Scholz. We highlight the latest advances in genetics and pathology. @liddelowsa.bsky.social Check it out! www.sciencedirect.com/science/arti...

sciencedirect.com

Advances in the genetics and pathology of Lewy body dementia

Lewy body dementia is a heterogeneous disease that is underdiagnosed and poorly understood. Pathologically, Lewy body dementia is characterised by the…

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oZgun Gokce @gokcegroup.bsky.social · 11/11/2025

In case you were wondering what to do with precisely 150 minutes of your existence @sfn.org #SfN25 #SanDiego. Join our mini-symposium Single-Cell Multiomics in CNS Injury and Recovery. Guaranteed to contain many glial cells and at least a neuron. I am Co-chairing with Naomi Habib

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Shane Liddelow @liddelowsa.bsky.social · 10/11/2025

@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below. Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social. (1/2)

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Wendy Xin @droligo.bsky.social · 29/10/2025

If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!

A flyer displaying the same information as written in the post, with two images of two astrocytes around a blood vessel and one newly formed oligodendrocyte, along with logs our sponsors Avantor and Plasmidsaurus.

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Gonçalo Castelo-Branco @gocastelobranco.bsky.social · 05/11/2025

Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com www.nature.com/articles/s41...

nature.com

Spatial dynamics of brain development and neuroinflammation - Nature

A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 02/11/2025

Oligodendrocytes support functional development of subcortical premotor neurons and navigation www.biorxiv.org/content/10.1101/202…

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Shane Liddelow @liddelowsa.bsky.social · 24/10/2025

We've been doing some amazing stuff outside the astrocyte realm. Check out our latest Oligo investigation led by @pryprk.bsky.social !

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The Transmitter @thetransmitter.bsky.social · 04/09/2025

Astrocyte networks are much larger than previously thought, which “flips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social. By @callimcflurry.bsky.social #neuroskyence www.thetransmitter.org/astrocytes/a...

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Shane Liddelow @liddelowsa.bsky.social · 03/09/2025

Great story in the @thetransmitter.bsky.social today by @callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks. Read the story here: www.thetransmitter.org/astrocytes/a... Read the preprint here: www.biorxiv.org/content/10.1...

thetransmitter.org

Astrocyte networks span large swaths of brain

The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.

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Shane Liddelow @liddelowsa.bsky.social · 18/08/2025

A fantastic time with an excellent group of trainees at the @neurochemistry.org Advanced School. Let the conference begin!

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Shane Liddelow @liddelowsa.bsky.social · 15/08/2025

are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social? LAST WEEK TO APPLY to be a SPiNES speaker for our next season. Details and apply here: med.nyu.edu/departments-... COME AND WOW US!

media.tenor.com

a black and white photo of a crowd of people standing and sitting in chairs .

ALT: a black and white photo of a crowd of people standing and sitting in chairs .

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Shane Liddelow @liddelowsa.bsky.social · 13/08/2025

The American Society for Neurochemistry (ASN) and the International Society for Neurochemistry (ISN) are hosting a discussion on autism, with clinical, research, family, & pharma perspectives. August 17, 2025 2-4 PM Hunter College, West Room 714 FREE Registration recommended: lnkd.in/dJY7hp-b

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Shane Liddelow @liddelowsa.bsky.social · 13/08/2025

#GliaPapers #GliaAugust2025 @wiley.com AUGUST COVER Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)

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bioRxivpreprint @biorxivpreprint.bsky.social · 22/07/2025

Astrocytes connect specific brain regions through plastic gap junctional networks www.biorxiv.org/content/10.1101/202…

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Shane Liddelow @liddelowsa.bsky.social · 22/07/2025

fantastic work from @melcooperphd.bsky.social - what are these beautiful networks doing in our brains?

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Shane Liddelow @liddelowsa.bsky.social · 18/07/2025

Was a lot of fun working on this piece with Ben Clayton for @annualreviews.bsky.social Reactive astrocyte heterogeneity is a thoroughly exciting and complicated problem... lots of exciting discoveries in recent years. www.annualreviews.org/content/jour...

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Shane Liddelow @liddelowsa.bsky.social · 11/07/2025

On now, last session of #Glia2025, and last presenter from the lab. S26 | Exploring glial diversity using single cell and spatial genomics @mrodea.bsky.social 10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain

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Shane Liddelow @liddelowsa.bsky.social · 09/07/2025

#glia2025 Liddelow Lab presentations start today! PS2 | Poster Session II Wednesday, 9 July 2025, 13:00 - 16:00 Room: Hall Garden Level T11-059B Understanding specific neuron-astrocyte interactions in neuroinflammation @sciencelemon92.bsky.social www.liddelowlab.com/francesco-li...

liddelowlab.com

Francesco Limone — Liddelow Lab

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Shane Liddelow @liddelowsa.bsky.social · 03/07/2025

#GliaPapers #GliaJuly2025 JULY COVER Stochastically labeled astrocytes (cyan) and Müller glia (magenta) contacting blood vessels (orange) and neural cell bodies and axons bundles (green) in a mouse retina. (see Holden, JM, et al, doi.org/10.1002/glia...)

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Shane Liddelow @liddelowsa.bsky.social · 30/06/2025

Thanks @analog-ashley.bsky.social and @thetransmitter.bsky.social - this was a fun piece to chat about. Lots of exciting astrocyte work coming out of labs the world over. Watch this space for new insights soon!

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Shane Liddelow @liddelowsa.bsky.social · 30/06/2025

Strong recommend. Great new PI, excellent institute and resources. Exciting questions to research!

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Shane Liddelow @liddelowsa.bsky.social · 15/06/2025

Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_... #Neuroscience #Postdoc #ResearchOpportunity

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Shane Liddelow @liddelowsa.bsky.social · 05/06/2025

#GliaPapers #GliaJune2025 JUNE COVER Mouse oligodendroglia (O4+ in green and nuclei in white) co-cultured with primary microglia (not shown in this image) after exposure to corticosterone.(See Madeira et al, doi.org/10.1002/glia...)

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Shane Liddelow @liddelowsa.bsky.social · 20/05/2025

Congratulations to @pryprk.bsky.social on this fantastic piece of work!

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Shane Liddelow @liddelowsa.bsky.social · 19/05/2025

SOLD OUT! @pintofscience.us is killing it with their preparations... next time we'll need a bigger bar! Looking forward to seeing everyone in two sleeps!

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Shane Liddelow @liddelowsa.bsky.social · 13/05/2025

come see me make a fool of myself while discussing neuroscience with a pint in my hand! ... its going to be fine right... right?!

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