Dementia Researcher Salon Debate - Biomedical vs Social Care Research

Fragile X Syndrome (FXS) is a common inherited neurodevelopmental condition, resulting from loss of Fragile X Messenger Ribonuclear Protein (FMRP). Rodent models of FXS display cellular hyperexcitabil...

The study of life, from molecules to populations. Includes biochemistry and virology

The balance between excitatory and inhibitory neurotransmission is fundamental for normal brain function, yet the adaptation of individual neurons to disrupted excitatory-inhibitory balance is not wel...

Longitudinal neuroimaging of participants with planned arm amputations shows that the cortical body map remains stable after amputation, with no evidence of hand or face reorganization, thus challengi...

Neuroscience; Molecular Biology; Developmental Biology

The principal layer architecture of the sensory cortex is altered with aging. The authors show that overall thinning of the primary somatosensory cortex is driven by deep layer degeneration but that l...

Grant rejection is part of every researcher’s journey — and it never stops, no matter your career stage. In this episode of the Dementia Researcher Podcast, host Dr Fiona McLean (Alzheimer’...

McGeachan et al. observe oligomeric tau in synapses from individuals with progressive supranuclear palsy and provide evidence that tau pathology may spread through the brain via synapses.

Ossenkoppele, Coomans and colleagues analyzed the tau PET data of 12,048 individuals from 42 cohorts worldwide. They found that age, amyloid-β status, presence of an APOE ε4 allele and female sex are ...

A cohort study of over 15,000 US adults found that the lifetime risk of developing dementia from ages 55 to 95 is 42%, with the highest risk in APOE ε4 carriers, women and Black adults, and projected ...

Edinburgh couple hope for treatment for rare neurological condition progressive supranuclear palsy.

A person aged 75 to 80 is less likely to have dementia today compared to someone of the same age several decades ago, a University of Queensland study has found.

What does it take to be a neuroscientist, editor, advocate, and public communicator all at once? In this interview, Professor Tara Spires-Jones shares her journey from studying synapses to shaping sci...

Adult female fruit flies proved less sensitive to disturbances of their circadian system through experimental disruptions of a peptide in their brains (green). Image credit: Eva Scholz-Carlson, Indian...

Genomic Imprinting Meeting will take place in Valencia, a dazzling city that beautifully blends history, art, and modernity, creating a captivating atmosphere for everyone who visits. Its historic cen...